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NIH funding notice PAR-15-079

Cutting-Edge Basic Research Awards (CEBRA) (R21)

Closed on December 20, 2017.

Posted
January 8, 2015
Close date
December 20, 2017
Activity codes
R21
Institutes taking part
NIDA

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

  1. Reissues: PAR-12-086 Cutting-Edge Basic Research Awards (CEBRA) (R21)
  2. 2 steps back: PAR-09-222 Cutting-Edge Basic Research Awards (CEBRA) (R21)
  3. 3 steps back: PAR-06-209 Cutting-Edge Basic Research Awards (CEBRA) (R21)
  4. 4 steps back: PAR-03-017

Replaced by PAR-18-437.

Who won it before

61 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $11,884,726 in first-year total cost, median $193,340.

Most frequent study sections

  1. Special Emphasis Panel[ZDA1 JXR-G (09)]9
  2. Special Emphasis Panel[ZDA1 SXC-E (10)]9
  3. Special Emphasis Panel[ZDA1 JXR-D (12)]7
  4. Special Emphasis Panel[ZDA1 SXT-P (06)]7
  5. Special Emphasis Panel[ZDA1 GXM-A (13)]6

Most frequent institutions

  1. YALE UNIVERSITY4
  2. WASHINGTON UNIVERSITY3
  3. CALIFORNIA INSTITUTE OF TECHNOLOGY2
  4. SCRIPPS FLORIDA2
  5. SCRIPPS RESEARCH INSTITUTE, THE2
Competing awards under PAR-15-079 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2019Supramolecular Nanovaccines for Opioid Use Disorders1R21DA047138-01RALEIGH, MICHAEL DENNISRUDRA, JAIWASHINGTON UNIVERSITY, MO$193,057ZDA1
2018Application of intein-based chemical methods to directly manipulate neuronal histone modifications in rodent models of addiction1R21DA044767-01A1DAVID-SHTERNBERG, YAEL EMAZE, IAN S.ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY$230,626ZDA1
2018Measure Mu-opioid Receptor Desensitization in vivo1R21DA047133-01WEY, HSIAO-YINGMASSACHUSETTS GENERAL HOSPITAL, MA$205,079ZDA1
2018Light activated CRISPR epigenome editing in cocaine abuse1R21DA046227-01LOBO, MARY KAYUNIVERSITY OF MARYLAND BALTIMORE, MD$202,369ZDA1
2018Deep learning-based image analysis for assessing real-time smoking risk1R21DA047131-01MCCLERNON, FRANCIS JOSEPHDUKE UNIVERSITY, NC$200,208ZDA1
2018Bile acid signaling as a pharmacological target for the treatment of cocaine abuse1R21DA043960-01A1FLYNN, CHARLES RGALLI, AURELIOUNIVERSITY OF ALABAMA AT BIRMINGHAM, AL$195,885ZDA1
2018Trans-Synaptic Luminescent Opsins:Developing pathway-, cell type-, and synapse-specific optogenetics1R21DA047108-01HUANG, YANHUA HUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$195,625ZDA1
2018FGF21 and Drug Abuse1R21DA044766-01A1BIDLACK, JEAN MUNIVERSITY OF ROCHESTER, NY$192,500ZDA1
2018Imaging the monoaminergic midbrain and cognitive control in cocaine addiction1R21DA044749-01A1LI, CHIANG-SHAN RAYYALE UNIVERSITY, CT$183,750ZDA1
2018Imaging the behaviorally evoked neural ensemble dynamics of the locus coeruleus in healthy and addicted brains1R21DA046183-01SCHNITZER, MARK JSTANFORD UNIVERSITY, CA$176,488ZDA1
2018Allosteric regulation and phosphorylation homeostasis of PEA-15 in protection of brain microvascular endothelial cells against methamphetamine and HIV-1 Tat1R21DA046223-01WEI, YUFENGNEW JERSEY CITY UNIVERSITY, NJ$143,355ZDA1
2017Effects of a G protein-biased mu opioid receptor agonist PZM21 in primates1R21DA044775-01KO, MEI-CHUANWAKE FOREST UNIVERSITY HEALTH SCIENCES, NC$219,436ZDA1
2017Syringe Injectable Electronics Platform for Chronic Mapping and Modulation of Neural Circuits in Addiction1R21DA043985-01LIEBER, CHARLES MHARVARD UNIVERSITY, MA$211,250ZDA1
2017Imaging Synaptic Density in the Cocaine-Addicted Brain In Vivo using 11C UCB J PET1R21DA044005-01MALISON, ROBERT TYALE UNIVERSITY, CT$209,375ZDA1
2017Neurobiology of care giving in opioid dependent mothers1R21DA043983-01A1LANGLEBEN, DANIEL DUNIVERSITY OF PENNSYLVANIA, PA$206,528ZDA1
2017Addiction, Gender and Endocrine Disruptors1R21DA042599-01A1LYNCH, WENDY JEANRISSMAN, EMILIE F.NORTH CAROLINA STATE UNIVERSITY RALEIGH, NC$203,397ZDA1
2017Neural circuit impacts of hallucinogens1R21DA041857-01A1JI, DAOYUNBAYLOR COLLEGE OF MEDICINE, TX$198,125ZDA1
2017Explore in vivo functional connectivity at cellular resolution in drugged brains1R21DA044007-01A1GUO, SUUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$198,125ZDA1
2017Does GPR119 mediate the beneficial metabolic effects of THC?1R21DA044004-01MACKIE, KENNETHTRUSTEES OF INDIANA UNIVERSITY, IN$196,406ZDA1
2017Microglia and Opioid Withdrawal1R21DA044757-01NEUMAIER, JOHN FUNIVERSITY OF WASHINGTON, WA$193,750ZDA1
2017Nanoprobes for neurotransmitter-sensitive molecular fMRI in addiction research1R21DA044748-01JASANOFF, ALANMASSACHUSETTS INSTITUTE OF TECHNOLOGY, MA$193,375ZDA1
2017Robotics may help unravel the biological determinants of substance use disorders: studies in zebrafish1R21DA042558-01A1PORFIRI, MAURIZIONEW YORK UNIVERSITY, NY$173,125ZDA1
2017Optical montoring of modulatory neurotransmitter levels using new infrared nanonsensors1R21DA044010-01A1WILBRECHT, LINDA EUNIVERSITY OF CALIFORNIA BERKELEY, CA$138,395ZDA1
2017Nanoparticle-Mesenchymal Stem Cell conjugates for cell therapy in drug addiction1R21DA043959-01POPOVTZER, RACHELAYADID, GAL MOSHEBAR-ILAN UNIVERSITY$102,340ZDA1
2016Enzympharmacotherapy for attenuating nicotine's psychoactive effects1R21DA041839-01A1JANDA, KIMSCRIPPS RESEARCH INSTITUTE, THE, CA$240,625ZDA1
2016Causally connecting neural activity to behavior with caged compounds1R21DA041725-01NICOLA, SALEEM MALBERT EINSTEIN COLLEGE OF MEDICINE, INC, NY$208,750ZDA1
2016The Unlearning of Stimulus-Outcome Associations through Intracortical Microstimulation1R21DA041791-01WALLIS, JONI DUNIVERSITY OF CALIFORNIA BERKELEY, CA$195,465ZDA1
2016A Novel Mechanism for Decreasing Opioid Reward1R21DA042584-01HOHMANN, ANDREA GRACEREBEC, GEORGE VINCENTTRUSTEES OF INDIANA UNIVERSITY, IN$195,156ZDA1
2016Optical platform to image neuronal and vascular effects of cocaine in awake rodents1R21DA042597-01DU, CONGWUPAN, YINGTIANSTATE UNIVERSITY NEW YORK STONY BROOK, NY$195,071ZDA1
2016Lipidomics analysis of identified single neurons in the adult rodent brain1R21DA041776-01PIOMELLI, DANIELEUNIVERSITY OF CALIFORNIA-IRVINE, CA$193,125ZDA1
2016Quantitative Neurovascular Imaging for Drug Abuse Research1R21DA042583-01SRIDHAR, SRINIVASNORTHEASTERN UNIVERSITY, MA$193,125ZDA1
2016In vivo imaging of dynamic structural plasticity driving morphine conditioned place preference1R21DA042581-01HAN, EDWARD BINGMORON-CONCEPCION, JOSE AWASHINGTON UNIVERSITY, MO$190,625ZDA1
2016Technology for Identification of Epiproteomes in Tissue Samples1R21DA041822-01TACKETT, ALANUNIV OF ARKANSAS FOR MED SCIS, AR$186,250ZDA1
2016Cell-type Specific Psychostimulant Effects on the Neuronal Translatome1R21DA040454-01A1NAIRN, ANGUS C.YALE UNIVERSITY, CT$183,750ZDA1
2015Cocaine abuse and plasticity in the lateral hypothalamus1R21DA040458-01 · under PAR-12-086SANNA, PIETRO PSCRIPPS RESEARCH INSTITUTE, THE, CA$247,175ZDA1
2015A transgenic model of opioid tolerance and drug discovery1R21DA040406-01 · under PAR-12-086GRILL, BROCKMARTEMYANOV, KIRILL A.SCRIPPS FLORIDA, FL$240,000ZDA1
2015Dynamic Contrast-Enhanced MRI to Measure Blood-Brain Barrier Permeability in Substance Abusers1R21DA040436-01 · under PAR-12-086COMER, SANDRA DNEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC, NY$213,761ZDA1
2015Impact of Cannabinoid Use on HIV-related Brain Alterations in Young Adults1R21DA037667-01A1 · under PAR-12-086FENNEMA-NOTESTINE, CHRISTINENICHOLS, SHARON LUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$193,750ZDA1
2015Optogenetic Toolbox for Studying Regulators of G-Protein Signaling in Addiction1R21DA040434-01 · under PAR-12-086CHOW, BRIAN YUNIVERSITY OF PENNSYLVANIA, PA$193,340ZDA1
2015A novel RNA-guided platform for dissecting cannabinoid signaling in reward circuit development1R21DA038447-01A1 · under PAR-12-086GUO, SUUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$192,424ZDA1
2015High throughput multicompartment culture chambers to develop neurocircuit models of addiction risk1R21DA039686-01 · under PAR-12-086HART, RONALD PPANG, ZHIPING P.ZAHN, JEFFREY DRUTGERS, THE STATE UNIV OF N.J., NJ$191,622ZDA1
2015A novel approach for identifying addiction vulnerability in animals.1R21DA037728-01A1 · under PAR-12-086GEWIRTZ, JONATHANHARRIS, ANDREW CHARLESUNIVERSITY OF MINNESOTA, MN$191,495ZDA1
2015Flexible and inducible gene knockdown in rat neurons: BDNF and drug addiction1R21DA039681-01 · under PAR-12-086WONG-RILEY, MARGARET TTMEDICAL COLLEGE OF WISCONSIN, WI$191,250ZDA1
2015Beta-ketoamphetamines: Window to the Neurotoxic Mechanisms of Methamphetamine1R21DA039667-01 · under PAR-12-086KUHN, DONALD MWAYNE STATE UNIVERSITY, MI$190,938ZDA1
2015Preserving opioid analgesia using a novel adenosinergic approach1R21DA040305-01 · under PAR-12-086SALVEMINI, DANIELASAINT LOUIS UNIVERSITY, MO$189,375ZDA1
2015Development of a rat model of cannabis smoke self-administration1R21DA039701-01 · under PAR-12-086MAURER, ANDREW PORTERSETLOW, BARRYUNIVERSITY OF FLORIDA, FL$187,500ZDA1
2015Exploring nucleocytoplasmic IEG mRNA export in striatal neuron subpopulations1R21DA037736-01A1 · under PAR-12-086KEEFE, KRISTEN AUNIVERSITY OF UTAH, UT$186,250ZDA1
2015Theranostic Pain Nanomedicines: imaging inflammation, reducing pain and need for opioids1R21DA039621-01 · under PAR-12-086JANJIC, JELENA MDUQUESNE UNIVERSITY, PA$165,000ZDA1
2014Neurodevelopmental impact of prenatal exposure to prescription pain medication1R21DA036376-01A1 · under PAR-12-086MILLER, COURTNEY ASCRIPPS FLORIDA, FL$236,250ZDA1
2014GLP-1 Receptors and Psychostimulant Addiction1R21DA035588-01A1 · under PAR-12-086GALLI, AURELIOSTANWOOD, GREGG DVANDERBILT UNIVERSITY, TN$235,125ZDA1
2014Menthol as a chaperone for nicotonic receptors1R21DA037743-01 · under PAR-12-086LESTER, HENRY A.CALIFORNIA INSTITUTE OF TECHNOLOGY, CA$208,125ZDA1
2014Probing the circadian clock in zebrafish larvae with in situ single cell transcri1R21DA038468-01 · under PAR-12-086CAI, LONGCALIFORNIA INSTITUTE OF TECHNOLOGY, CA$208,125ZDA1
2014Using Control Systems to Predict Individualized Dynamics of Nicotine Cravings1R21DA038467-01 · under PAR-12-086MUJICA-PARODI, LILIANNE RSTATE UNIVERSITY NEW YORK STONY BROOK, NY$206,543ZDA1
2014Optogenetic Targeting of mGluR5 Receptor Signaling1R21DA037741-01 · under PAR-12-086OLIVE, M. FOSTERARIZONA STATE UNIVERSITY-TEMPE CAMPUS, AZ$192,865ZDA1
2014Long noncoding RNAs and chromatin regulation in cocaine addiction1R21DA035592-01A1 · under PAR-12-086WAHLESTEDT, CLAES ROBERTUNIVERSITY OF MIAMI SCHOOL OF MEDICINE, FL$191,875ZDA1
2014Heroin Addiction: Predicting Vulnerability & Identification of a Novel Treatment1R21DA035608-01A1 · under PAR-12-086LEVENSON, ROBERTPENNSYLVANIA STATE UNIV HERSHEY MED CTR, PA$191,250ZDA1
2014DEVELOPMENT OF A NOVEL APPROACH TO STUDY ALTERNATIVE TRANSLATION IN THE CNS1R21DA038458-01 · under PAR-12-086DOUGHERTY, JOSEPH DWASHINGTON UNIVERSITY, MO$190,625ZDA1
2014Drug repurposing study for tobacco dependence treatment using zebrafish1R21DA035546-01A1 · under PAR-12-086KLEE, ERIC WMAYO CLINIC ROCHESTER, MN$184,152ZDA1
2014A role for vitamin D in drug addiction1R21DA037657-01 · under PAR-12-086DILEONE, RALPH JYALE UNIVERSITY, CT$177,375ZDA1
2014Theory of Resurgence of Cocaine Seeking1R21DA037725-01 · under PAR-12-086SHAHAN, TIMOTHY AUTAH STATE UNIVERSITY, UT$173,550ZDA1
2014Opposing Roles of Distinct Output Projections From Prefrontal Cortex1R21DA037744-01 · under PAR-12-086SMITH, RACHEL JMEDICAL UNIVERSITY OF SOUTH CAROLINA, SC$170,475ZDA1

Data: Grants.gov's daily extract and NIH's notice pages and award files, in ScienceGraph release conductgrants-2026-11-09-0.1.0. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.

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