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NIH funding notice PAR-15-340

NCI Exploratory/Developmental Research Grant Program (NCI Omnibus R21)

Closed on November 10, 2015.

Posted
September 1, 2015
Close date
November 10, 2015
Activity codes
Not stated on the notice page
Institutes taking part
Not stated on the notice page

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

Its page was not saved, so the notices it replaced are not known.

Who won it before

78 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $15,611,348 in first-year total cost, median $200,644.

Most frequent study sections

  1. Special Emphasis Panel[ZCA1 SRB-X (M1)]9
  2. Special Emphasis Panel[ZCA1 RTRB-F (M1)]8
  3. Special Emphasis Panel[ZCA1 SRB-2 (M1)]8
  4. Special Emphasis Panel[ZCA1 SRB-J (M1)]8
  5. Special Emphasis Panel[ZCA1 RTRB-E (M1)]7

Most frequent institutions

  1. BAYLOR COLLEGE OF MEDICINE3
  2. SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE3
  3. UNIVERSITY OF PITTSBURGH AT PITTSBURGH3
  4. CASE WESTERN RESERVE UNIVERSITY2
  5. GEORGETOWN UNIVERSITY2
Competing awards under PAR-15-340 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2016Sh3gl2 and chemosensitivity of bladder cancer1R21CA198722-01A1ADAM, ROSALYN MBOSTON CHILDREN'S HOSPITAL, MA$282,050ZCA1
2016Development of circulating biomarker for lung cancer1R21CA198558-01A1HUANG, QIHONGWISTAR INSTITUTE, PA$266,623ZCA1
2016Oncogene Addiction Biomarkers for a KRAS Therapy1R21CA201707-01A1POWIS, GARTHSANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE, CA$254,475ZCA1
2016Identification of the molecular mechanism of miR-211 and its target genes in melanocytes and pigmented melanoma senescence and apoptosis1R21CA202197-01A1PERERA, RANJAN JOSEPHSANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE, CA$254,475ZCA1
2016Evaluating the Effect of the Breast Density Legislation on Supplemental Screening1R21CA209442-01HENDERSON, LOUISEUNIV OF NORTH CAROLINA CHAPEL HILL, NC$248,710ZCA1
2016Targeting Beta-Adrenergic Signaling to Control GVH and GVL Responses1R21CA202358-01A1CAO, XUEFANGROSWELL PARK CANCER INSTITUTE CORP, NY$245,900ZCA1
2016New methods to address dilemmas in mixed recurrent-event and panel-count data1R21CA198641-01A1ZHU, LIANGUNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON, TX$240,361ZCA1
2016Kinase Dependent Chemotherapy Resistance Mechanisms in Small Cell Lung Cancer1R21CA209121-01KERN, JEFFREY ANATIONAL JEWISH HEALTH, CO$237,381ZCA1
2016Mechanism of Ikaros Tumor Suppression in progenitor B cell leukemia1R21CA209229-01FRIETZE, SETH ESCHJERVEN, HILDEUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$235,196ZCA1
2016A Question Prompt List to Promote Communication in Genomic Medicine1R21CA201827-01A1O'NEILL, SUZANNE C.GEORGETOWN UNIVERSITY, DC$233,416ZCA1
2016Systematic Programmed Illumination (sPI) of Hospital Rooms to Prevent/Reduce Cancer-Related Fatigue During Hematopoeitic Stem Cell Transplantation for Multiple Myeloma1R21CA209419-01REDD, WILLIAM HICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY$233,051ZCA1
2016The role of IL-27 cytokine in hepatocellular carcinoma (HCC) development1R21CA202396-01A1KOLTSOVA, EKATERINARESEARCH INST OF FOX CHASE CAN CTR, PA$232,943ZCA1
2016Phase II Trial of Nicotinamide Riboside for Relief of Taxane-Induced Sensory Neuropathy1R21CA208968-01HAMMOND, DONNA LTHOMAS, ALEXANDRAUNIVERSITY OF IOWA, IA$232,181ZCA1
2016Prostate Specific Membrane Antigen Targeted Photoacoustic Imaging for Prostate Cancer1R21CA202199-01A1BOCTOR, EMAD MCHEN, YINGJOHNS HOPKINS UNIVERSITY, MD$227,205ZCA1
2016New approaches to target protein intramolecular interactions1R21CA208363-01CHEN, JIANDONGH. LEE MOFFITT CANCER CTR & RES INST, FL$224,460ZCA1
2016Acupressure Intervention to Improve Fatigue and Physical Functioning of Chinese Immigrant Breast Cancer Survivors1R21CA209213-01WANG, JUDY HUEI-YUGEORGETOWN UNIVERSITY, DC$219,496ZCA1
2016Follow-up care and preventive service use among survivors of adolescent and young adult cancer.1R21CA198042-01A1CHAO, CHUN R.KAISER FOUNDATION RESEARCH INSTITUTE, CA$217,666ZCA1
2016Using DNA methylation markers to improve the predictive accuracy and utility of needle biopsiesfor determining prostate cancer aggressiveness1R21CA201865-01A1GILL, INDERBIRLIANG, GANGNINGUNIVERSITY OF SOUTHERN CALIFORNIA, CA$215,325ZCA1
2016In vivo imaging of tumor heterogeneity generation from endogenous single cells1R21CA209012-01FRASER, SCOTT EUNIVERSITY OF SOUTHERN CALIFORNIA, CA$215,325ZCA1
2016Identifying epigenetic targets of c-myc oncogene1R21CA205172-01A1WU, SONGZONG, WEI-XINGRUTGERS, THE STATE UNIV OF N.J., NJ$214,082ZCA1
2016PSGL-1, a New Player in the Immune Checkpoint Landscape1R21CA209627-01BRADLEY, LINDA MAC PHERSONSANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE, CA$212,063ZCA1
2016Molecular Pathways of Interleukin-13 in Cutaneous T-cell Lymphoma1R21CA209107-01FUSCHIOTTI, PATRIZIAUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$211,603ZCA1
2016CMV infection and NK-cell therapy for multiple myeloma1R21CA197527-01A1REZVANI, KATYSIMPSON, RICHARD JUNIVERSITY OF HOUSTON, TX$211,261ZCA1
2016Systemic delivery of miR-29 for basal-like breast cancer treatment1R21CA209045-01SHU, DANXU, RENUNIVERSITY OF KENTUCKY, KY$211,076ZCA1
2016Identifying the biosynthesis of a potent cytotoxic agent Lasonolide A1R21CA209189-01WANG, GUOJUNFLORIDA ATLANTIC UNIVERSITY, FL$209,674ZCA1
2016Overcoming Primary Ibrutinib Resistance in Mantle Cell Lymphoma Using Patient-Derived Models and Molecular Profiling1R21CA202104-01A1WANG, MICHAELUNIVERSITY OF TX MD ANDERSON CAN CTR, TX$208,800ZCA1
2016Assessing deformable image registration in the lung using hyperpolarized-gas MRI1R21CA195317-01A1CAI, JINGMILLER, G. WILSONDUKE UNIVERSITY, NC$207,860ZCA1
2016New mechanisms of breast cancer metastasis and loss of estrogen receptor driven by 14-3-31R21CA198041-01A1LIN, WEEI-CHINBAYLOR COLLEGE OF MEDICINE, TX$206,843ZCA1
2016ESTABLISHING A CONDITIONAL TELOMERASE KNOCK-IN ALLELE IN A HAPLOID CANCER CELL LINE TO IDENTIFY REGULATORS OF ALT THROUGH GENETIC FORWARD SCREENS1R21CA198701-01A1SAHIN, ERGUNBAYLOR COLLEGE OF MEDICINE, TX$206,843ZCA1
2016Targeting B cell activating factor receptor (BAFF-R) as a novel therapeutic strategy for drug resistant Acute Lymphoblastic Leukemia (ALL)1R21CA201775-01A1PARAMESWARAN, RESHMICASE WESTERN RESERVE UNIVERSITY, OH$206,843ZCA1
2016Mechanisms underlying the protective effect of exercise and weight maintenance on metastatic progression in breast cancer1R21CA209144-01ROGERS, CONNIE JPENNSYLVANIA STATE UNIVERSITY, THE, PA$205,146ZCA1
2016Identifying insulin resistance biomarkers and metabolomic signature as predictors of precursors to pancreatic cancer1R21CA209366-01SCHMIDT, CHRISTIAN MAXIMILLIANZHANG, JIANJUNINDIANA UNIVERSITY INDIANAPOLIS, IN$203,906ZCA1
2016Using the Collaborative Cross for Model Studies of Intestinal Cancer1R21CA202496-01A1SIRACUSA, LINDA DTHOMAS JEFFERSON UNIVERSITY, PA$203,580ZCA1
2016A dedicated two dimensional antiscatter grid for CBCT in radiation therapy1R21CA198462-01A1ALTUNBAS, CEMUNIVERSITY OF COLORADO DENVER, CO$202,928ZCA1
2016Discovering and Characterizing Novel Pregnancy-Associated Cancers1R21CA208793-01CRUMP, CASEYSIEH, WEIVASUNDQUIST, KRISTINAICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY$202,673ZCA1
2016Structural Analysis of Cancerous Inhibitor of PP2A (CIP2A)1R21CA201944-01A1XU, WENQINGUNIVERSITY OF WASHINGTON, WA$201,623ZCA1
2016Development of DNA Polymerase θ Inhibitors for Precision Medicine in BRCA Deficient Cancers1R21CA209281-01POMERANTZ, RICHARD TTEMPLE UNIV OF THE COMMONWEALTH, PA$201,144ZCA1
2016Dim light at night alters pancreatic cell signaling and predisposes to pancreatic adenocarcinoma1R21CA202745-01A1NELSON, RANDY J.OHIO STATE UNIVERSITY, OH$200,970ZCA1
2016SFK-inhibitor enhancement of ATRA-mediated differentiation of APL1R21CA201831-01A1REDNER, ROBERT LUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$200,970ZCA1
2016Targeting cytokine mediated CREB activation in pancreatic cancer1R21CA209536-01NAGATHIHALLI, NAGARAJ S.UNIVERSITY OF MIAMI SCHOOL OF MEDICINE, FL$200,318ZCA1
2016Unlocking the Therapeutic Potential of Retinoic Acid in Acute Myeloid Leukemia1R21CA202488-01A1SWORDS, RONAN THOMASUNIVERSITY OF MIAMI SCHOOL OF MEDICINE, FL$200,318ZCA1
2016Heat shock proteins and modulation of immune responses1R21CA208833-01BINDER, ROBERT JUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$200,030ZCA1
2016Identification of Long Non-coding RNAs as Novel Biomarkers for Heterogeneous Glioblastomas1R21CA209345-01CHENG, SHI-YUANZHANG, WEINORTHWESTERN UNIVERSITY AT CHICAGO, IL$199,629ZCA1
2016Validation of FOXM1 as a new therapeutic target in high-risk myeloma1R21CA187388-01A1JANZ, SIEGFRIEDUNIVERSITY OF IOWA, IA$199,013ZCA1
2016Re-sensitizing ER-Alpha Mutant Breast Cancer Cells to Hormonal Therapy1R21CA209154-01LI, RONGUNIVERSITY OF TEXAS HLTH SCIENCE CENTER, TX$199,013ZCA1
2016A novel oncogenic driver in Ewing sarcoma1R21CA202485-01A1SHIIO, YUZURUUNIVERSITY OF TEXAS HLTH SCIENCE CENTER, TX$199,013ZCA1
2016p16 mechanisms in melanoma1R21CA201757-01A1GROSSMAN, DOUGLASUNIVERSITY OF UTAH, UT$197,055ZCA1
2016Recruitment of melanoma-specific CD4+ T cells1R21CA209551-01WILLIAMS, MATTHEW AUNIVERSITY OF UTAH, UT$197,055ZCA1
2016Role of TFIIS.h in regulation of p53 responsive apoptosis and tumor suppression1R21CA201889-01A1LU, HUATULANE UNIVERSITY OF LOUISIANA, LA$196,403ZCA1
2016The role of KIF2C/AURKA signaling in cilia loss and progression of glioblastoma.1R21CA208875-01PUGACHEVA, ELENA NIKOLAEVNAWEST VIRGINIA UNIVERSITY, WV$195,750ZCA1
2016Preventing postpartum smoking relapse: a twitter-enabled supportive intervention1R21CA198036-01A1WEN, KUANG-YIRESEARCH INST OF FOX CHASE CAN CTR, PA$194,119ZCA1
2016Diet-dependent regulation of DCIS progression1R21CA197896-01A1PORTER, WESTON WTEXAS A&M AGRILIFE RESEARCH, TX$193,793ZCA1
2016Altered mitochondria-ER signaling as a cause of chemotherapy resistance1R21CA198430-01A1HOGARTY, MICHAEL DCHILDREN'S HOSP OF PHILADELPHIA, PA$193,314ZCA1
2016Biophysical and Mechanistic Determinants for Cancer Cell Import of Hydrocarbon-Stapled Peptides1R21CA209358-01WALENSKY, LOREN DAVIDDANA-FARBER CANCER INST, MA$190,313ZCA1
2016High Throughput Mechanical Modulatory Assay for Breast Cancer Drug Testing1R21CA210126-01AGAH, MASOUDVIRGINIA POLYTECHNIC INST AND ST UNIV, VA$186,775ZCA1
2016Targeting the glucocorticoid receptor in enzalutamide resistant prostate cancer1R21CA202122-01A1GARABEDIAN, MICHAEL J.NEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY$184,331ZCA1
2016Regulating centrosome homeostasis through the UPS1R21CA202200-01A1PAGANO, MICHELENEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY$184,331ZCA1
2016Repurposing statins to enhance efficacy of BCL-2 antagonists in blood cancer1R21CA209341-01FRUMAN, DAVID ALEXANDERUNIVERSITY OF CALIFORNIA-IRVINE, CA$178,474ZCA1
2016Prevention of radiation-induced neurocognitive dysfunction by induced adult neural stem cell1R21CA202785-01A1KAI, MIHOKOJOHNS HOPKINS UNIVERSITY, MD$177,353ZCA1
2016Immunological manipulation of resistance to molecularly targeted inhibitors1R21CA209375-01TURK, MARY JODARTMOUTH COLLEGE, NH$176,175ZCA1
2016Augmented homologous recombination as a mechanism of acquired temozolomide resistance in glioblastoma1R21CA202403-01A1BURMA, SANDEEPUT SOUTHWESTERN MEDICAL CENTER, TX$176,131ZCA1
2016Deciphering Autophagy-Dependent Secretion In Cancer Via Proximity-Based Biotinylation1R21CA201849-01A1DEBNATH, JAYANTAUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$172,369ZCA1
2016ALK causes TGF-beta insensitivity in lung cancer cells1R21CA209007-01FENG, XIN-HUABAYLOR COLLEGE OF MEDICINE, TX$172,369ZCA1
2016Repurposing Anti-cancer Drugs to Prevent Growth of Osteosarcoma Metastases1R21CA209304-01GREENFIELD, EDWARD M.CASE WESTERN RESERVE UNIVERSITY, OH$172,369ZCA1
2016MicroRNAs Modulate Therapy Resistance in Prostate Cancer1R21CA202404-01A1NADIMINTY, NAGALAKSHMIUNIVERSITY OF CALIFORNIA AT DAVIS, CA$170,738ZCA1
2016Targeting MMP-9 for breast cancer therapy (R21 CA205471 Resubmission)1R21CA205471-01A1RADISKY, EVETTE SMAYO CLINIC JACKSONVILLE, FL$170,408ZCA1
2016HSC-Independent Mechanisms Underlying JMML1R21CA202296-01A1CHAN, REBECCA J.YODER, MERVIN C.INDIANA UNIVERSITY INDIANAPOLIS, IN$169,650ZCA1
2016Using zebrafish to study the role of six1a/b and microRNA-30a in rhabdomyosarcoma (RMS) initiation and progression1R21CA201809-01A1ARTINGER, KRISTINFORD, HEIDE L.UNIVERSITY OF COLORADO DENVER, CO$169,106ZCA1
2016Trace element supplementation to enhance calcium-mediated suppression of human colon adenoma growth1R21CA201782-01A1VARANI, JAMESUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$168,563ZCA1
2016Inhibiting Basal Cell Carcinoma By Promoting Cellular Differentiation1R21CA209166-01WONG, SUNNY YUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$168,563ZCA1
2016Neurotensin in Fibrolamellar Liver Cancer1R21CA201867-01A1RIEHLE, KIMBERLY JUNIVERSITY OF WASHINGTON, WA$168,019ZCA1
2016Role of SETBP1 in adult Ph+ acute lymphoblastic leukemia1R21CA209183-01PERROTTI, DANILOUNIVERSITY OF MARYLAND BALTIMORE, MD$167,475ZCA1
2016Delineating roles for a novel tri-protein complex (TRIM44) in the multiple myeloma stem cell niche1R21CA202212-01A1MCCARTY, NAMIUNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON, TX$167,475ZCA1
2016The Role of hnRNP L in Non-Small Cell Lung Cancer1R21CA201195-01A1PARK, MARGARET AMYVIRGINIA COMMONWEALTH UNIVERSITY, VA$165,844ZCA1
2016Bifunctional ligand development for targeted Positron Emission Tomography (PET) using Zirconium-891R21CA201999-01A1LEWIS, JASON S.SLOAN-KETTERING INST CAN RESEARCH, NY$161,344ZCA1
2016PRMT1-mediated metabolic reprogramming in leukemia progression1R21CA202390-01A1KLUG, CHRISTOPHERZHAO, XINYANGUNIVERSITY OF ALABAMA AT BIRMINGHAM, AL$159,863ZCA1
2016Gene-Gene Interactions and Their Functional Roles in Prostate Cancer Aggressiveness1R21CA202417-01A1LIN, HUI-YILSU HEALTH SCIENCES CENTER, LA$147,791ZCA1
2016Stem Cell-Adrenomedullin Therapy for Cancer Linked Lymphedema1R21CA201940-01A1HU, MICKEY C-TSTANFORD UNIVERSITY, CA$74,569ZCA1

Data: Grants.gov's daily extract and NIH's notice pages and award files, in ScienceGraph release conductgrants-2026-11-09-0.1.0. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.

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