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NIH funding notice PAR-16-041

Drug Discovery For Nervous System Disorders (R01)

Closed on January 7, 2019.

Posted
November 24, 2015
Close date
January 7, 2019
Activity codes
Not stated on the notice page
Institutes taking part
Not stated on the notice page

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

Its page was not saved, so the notices it replaced are not known.

Who won it before

19 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $12,952,048 in first-year total cost, median $534,125.

Most frequent study sections

  1. Drug Discovery for the Nervous System Study Section[DDNS]17
  2. Drug Discovery for the Nervous System Study Section[DDNS-R]1
  3. Special Emphasis Panel[ZRG1 MDCN-G (05)]1

Most frequent institutions

  1. UNIVERSITY OF CALIFORNIA, SAN DIEGO2
  2. VANDERBILT UNIVERSITY2
  3. ALBANY COLLEGE OF PHARMACY1
  4. BRIGHAM AND WOMEN'S HOSPITAL1
  5. J. DAVID GLADSTONE INSTITUTES1
Competing awards under PAR-16-041 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2019Identification and Development of Tau-Lowering Small-Molecule Drugs1R56AG060631-01A1MUCKE, LENNARTJ. DAVID GLADSTONE INSTITUTES, CA$1,703,867DDNS
2019Discovery of mGlu receptor PAMs for treatment of schizophrenia1R01MH119673-01CONN, P JEFFREYVANDERBILT UNIVERSITY, TN$752,218DDNS
2019Novel Protein Aggregation Inhibitors and Upper Motor Neuron Stabilizers for ALS and other Neurodegenerative Diseases1R01AG061708-01A1OZDINLER, PEMBE HANDESILVERMAN, RICHARD BNORTHWESTERN UNIVERSITY AT CHICAGO, IL$671,753DDNS
2019High Throughput screen to identify "first of their kind" activators of ADCY101R01AG061290-01BUCK, JOCHENLEVIN, LONNY RWEILL MEDICAL COLL OF CORNELL UNIV, NY$566,037DDNS
2019Discovery and development of novel glycine transporter-2 inhibitors for the treatment of neuropathic pain1R01DA048879-01CIOFFI, CHRISTOPHER L.VANDENBERG, ROBERT JOHNALBANY COLLEGE OF PHARMACY, NY$534,125DDNS
2019Antisense Oligonucleotides targeting APP to prevent neurodegeneration in models of Down Syndrome and Alzheimer's disease1R01AG061151-01MOBLEY, WILLIAM CUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$463,515DDNS
2019Hyperphosphorylated tau aggregation-based Alzheimer’s disease early drug discovery1R01AG062435-01KUO, MIN-HAOMICHIGAN STATE UNIVERSITY, MI$431,676DDNS
2019Structural Determinants of Allosteric Modulation of Brain GPCRs1R01DA046138-01A1MEILER, JENSVANDERBILT UNIVERSITY, TN$394,756DDNS
2019A Brain Penetrating Bi-functional Transferrin Receptor Antibody-TNF-alpha Decoy Receptor Fusion Protein for Alzheimer's Disease1R01AG062840-01A1SUMBRIA, RACHITAKECK GRADUATE INST OF APPLIED LIFE SCIS, CA$390,183DDNS
2019Antisense Oligonucleotides for Targeting Nonsense-mediated mRNA Decay in Frontotemporal Dementia1R01AG064069-01NGUYEN, ANDREW D.SAINT LOUIS UNIVERSITY, MO$375,403DDNS
2018AD Immunotherapy with a Novel CDC-Mutant Anti-Pyroglutamate-3 Abeta Antibody to Avoid Vascular Side Effects1RF1AG058657-01LEMERE, CYNTHIA ABRIGHAM AND WOMEN'S HOSPITAL, MA$2,151,385DDNS
2018Impact of Physical Activity on Striatal Reinnervation in a Nonhuman Primate Model of Parkinson's Disease1R56AG059284-01DAADI, MARCELTEXAS BIOMEDICAL RESEARCH INSTITUTE, TX$710,357DDNS
2018Treating Alzheimer's disease by reducing brain insulin resistance with incretin receptor agonists1R01AG057658-01COLE, GREGORY MTALBOT, KONRADUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$682,885DDNS
2018Treating with Gamma-Secretase Modulators to Prevent Neurodegeneration in Mouse Models of Down Syndrome and Alzheimer Disease1R01AG055523-01A1MOBLEY, WILLIAM CUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$499,198DDNS
2018Regulation of Exosome Secretion as a novel therapeutic approach for Alzheimer's Disease1R01AG059799-01ROJAS, CAMILOSLUSHER, BARBARA STAUCHTSUKAMOTO, TAKASHIJOHNS HOPKINS UNIVERSITY, MD$492,421DDNS
2018Development of Attenuated Furoxans as Novel Therapies for Alzheimer's Disease1R01AG057598-01SCHIEFER, ISAAC TUNIVERSITY OF TOLEDO HEALTH SCI CAMPUS, OH$383,750DDNS
2017Pain drugs based on nicotinic receptor subtype antagonists1R01DA041454-01A1GEE, KELVIN W.UNIVERSITY OF CALIFORNIA-IRVINE, CA$790,424DDNS
2017Estrogen therapy and APOE4 risk in Alzheimer's tested in female EFAD mice1R01AG057008-01LADU, MARY JOTHATCHER, GREGORY R. JUNIVERSITY OF ILLINOIS AT CHICAGO, IL$578,095ZRG1
2017Effects of glycomacropeptide on memory and Alzheimer-related neuropathology1R01AG054562-01MCDONALD, MICHAEL PUNIVERSITY OF TENNESSEE HEALTH SCI CTR, TN$380,000DDNS

Data: Grants.gov's daily extract and NIH's notice pages and award files, in ScienceGraph release conductgrants-2026-11-09-0.1.0. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.

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