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NIH funding notice PAR-16-176

NCI Clinical and Translational Exploratory/Developmental Studies (R21)

Closed on January 24, 2018.

Posted
April 8, 2016
Close date
January 24, 2018
Activity codes
Not stated on the notice page
Institutes taking part
Not stated on the notice page

Read the notice on Grants.gov ยท NIH Guide page

The notices it replaced

Its page was not saved, so the notices it replaced are not known.

Who won it before

133 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $26,381,056 in first-year total cost, median $201,459.

Most frequent study sections

  1. Special Emphasis Panel[ZCA1 TCRB-V (M2)]8
  2. Special Emphasis Panel[ZCA1 SRB-1 (M2)]7
  3. Special Emphasis Panel[ZCA1 SRB-P (M2)]7
  4. Special Emphasis Panel[ZCA1 TCRB-J (J1)]7
  5. Special Emphasis Panel[ZCA1 SRB-A (O1)]6

Most frequent institutions

  1. UNIVERSITY OF TX MD ANDERSON CAN CTR8
  2. JOHNS HOPKINS UNIVERSITY4
  3. SLOAN-KETTERING INST CAN RESEARCH4
  4. BAYLOR COLLEGE OF MEDICINE3
  5. DANA-FARBER CANCER INST3
Competing awards under PAR-16-176 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2018Deciphering the metagenome-encoded pathway and domain structure for Palmerolide biosynthesis1R21CA205932-01A1BAKER, BILL JCHAIN, PATRICK S. G.MURRAY, ALISON ELIZABETHDESERT RESEARCH INSTITUTE, NV$325,324ZCA1
2018The role germline polymorphisms on ALL susceptibility1R21CA229922-01DUPUY, ADAM J.UNIVERSITY OF IOWA, IA$265,350ZCA1
2018Identifying novel regulatory activities on the surface of protein kinases1R21CA223347-01LUNDBLAD, VICTORIASALK INSTITUTE FOR BIOLOGICAL STUDIES, CA$251,082ZCA1
2018Validation of Siglec-6 as a novel target for cancer immunotherapy1R21CA229961-01MUTHUSAMY, NATARAJANRADER, CHRISTOPHSCRIPPS FLORIDA, FL$246,464ZCA1
2018Epigenomic Biomarkers to Manage Thyroid Nodule Overdiagnosis and Overtreatment1R21CA223367-01HAHN, MARIAYIM, JOHN HBECKMAN RESEARCH INSTITUTE/CITY OF HOPE, CA$242,633ZCA1
2018Identification of genomic drivers of brain metastases in renal cell carcinoma1R21CA220253-01A1BRASTIANOS, PRISCILLA KALIOPICARTER, SCOTTCHOUEIRI, TONIMASSACHUSETTS GENERAL HOSPITAL, MA$239,041ZCA1
2018Rpl22-Like1 as a Novel Prognostic Marker in Colorectal Cancer1R21CA216825-01A1WIEST, DAVID L.RESEARCH INST OF FOX CHASE CAN CTR, PA$238,815ZCA1
2018Development of molecular probes to investigate and drug the oncogenic Wnt/?-catenin/BCL9/B9L transcriptional complex1R21CA221683-01CARRASCO, RUBEN DDANA-FARBER CANCER INST, MA$229,576ZCA1
2018Identification of Plasma- and Exosome-Based Protein Biomarkers for Early Detection of Pancreatic Cancer Using SOMAscan Technology1R21CA218960-01A1LIBERMANN, TOWIA A.BETH ISRAEL DEACONESS MEDICAL CENTER, MA$228,375ZCA1
2018MALAT1 Depletion as a Therapeutic Strategy in Chronic Myelomonocytic Leukemia (CMML)1R21CA216757-01A1PADRON, ERICH. LEE MOFFITT CANCER CTR & RES INST, FL$224,460ZCA1
2018Mechanisms of action of dual compound oncogenic PIK3CA mutations1R21CA223789-01A1SCALTRITI, MAURIZIOSLOAN-KETTERING INST CAN RESEARCH, NY$224,068ZCA1
2018Modulating the DNA methylation program through UHRF1 antagonism1R21CA216673-01A1FRYE, STEPHEN VERNONSTRAHL, BRIAN DUNIV OF NORTH CAROLINA CHAPEL HILL, NC$223,654ZCA1
2018Patient-Specific Mutation-Derived Tumor Neoantigens as Targets for Cancer Immunotherapy in Smoldering Multiple Myeloma1R21CA223953-01PAREKH, SAMIRICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY$221,198ZCA1
2018Utility of RAS mimetics to block oncogenic signaling in colorectal cancer1R21CA227963-01REDDY, E PREMKUMARICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY$221,198ZCA1
2018Biomarkers of taxane chemotherapy response/resistance in prostate cancer1R21CA216800-01A1GIANNAKAKOU, PARASKEVIWEILL MEDICAL COLL OF CORNELL UNIV, NY$221,198ZCA1
2018Targeting of TCF4 PARylation in the vascular niche to obliterate chemoresistant hepatocarcinoma cells1R21CA230098-01CAO, ZHONGWEIICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY$221,198ZCA1
2018Image-Guided Drug Delivery and Treatment for GIST1R21CA223270-01CHOI, HAK SOOMASSACHUSETTS GENERAL HOSPITAL, MA$219,893ZCA1
2018Targeting chemoresistance in ovarian cancer1R21CA222425-01A1STORZ, PETERMAYO CLINIC JACKSONVILLE, FL$219,491ZCA1
2018A novel genetic pathway for survival of B-lymphoblastic leukemia-initiating cells1R21CA209298-01A1LI, SHAOGUANGUNIV OF MASSACHUSETTS MED SCH WORCESTER, MA$218,588ZCA1
2018Translational development studies of a novel combination therapy for castration-resistant prostate cancer1R21CA218774-01A1DENG, YIBINLU, JUNXUANPENNSYLVANIA STATE UNIV HERSHEY MED CTR, PA$214,380ZCA1
2018Imaging cell death in a preclinical rat model with metastatic osteosarcoma1R21CA229582-01GABRIELSON, KATHLEEN LOUISEJOHNS HOPKINS UNIVERSITY, MD$213,694ZCA1
2018Targeting Nodal/TGF-Beta pathway to inhibit invasion and growth of retinoblastoma1R21CA229919-01ASNAGHI, LAURAEBERHART, CHARLES GJOHNS HOPKINS UNIVERSITY, MD$213,694ZCA1
2018A pre-clinical x-ray/optical tomography-guided radiation research platform for pancreatic cancer1R21CA223403-01TRAN, PHUOC T.WANG, KEN KANG-HSINJOHNS HOPKINS UNIVERSITY, MD$213,667ZCA1
2018Role of MTF1 in ovarian cancer1R21CA216585-01A1YUE, JUNMINGUNIVERSITY OF TENNESSEE HEALTH SCI CTR, TN$213,180ZCA1
2018A novel N-Ras pathway driving DCIS to basal-like breast cancer1R21CA226567-01CHANG, ERIC CBAYLOR COLLEGE OF MEDICINE, TX$212,055ZCA1
2018Learning radiomic signatures to early predict response of rectal cancer patients to neoadjuvant chemoradiation therapy1R21CA223358-01FAN, YONGUNIVERSITY OF PENNSYLVANIA, PA$210,105ZCA1
2018Treating high grade intraepithelial lesions of the anus with photodynamic therapy1R21CA223366-01A1BEN-JOSEF, EDGARBUSCH, THERESA MUNIVERSITY OF PENNSYLVANIA, PA$210,105ZCA1
2018Preclinical safety and efficacy assessment of a novel PCNA inhibitor for prostate cancer therapy1R21CA223049-01DONG, ZHONGYUNUNIVERSITY OF CINCINNATI, OH$208,854ZCA1
2018Lipidomics-based biomarkers for risk of progression in early prostate cancer1R21CA223527-01DAVIS, JOHNTHOMPSON, TIMOTHY CHARLESUNIVERSITY OF TX MD ANDERSON CAN CTR, TX$208,800ZCA1
2018Co-targeting PDAC tumor cells and the microenvironment to succeed in EGFR/ErbB2-targeted therapy1R21CA223102-01YU, DIHUAUNIVERSITY OF TX MD ANDERSON CAN CTR, TX$208,800ZCA1
2018Manual Therapy for Fibrosis-related Late Effect Dysphagia in Head and Neck Cancer Survivors: The MANTLE Trial1R21CA226200-01HUTCHESON, KATHERINE ARNOLDUNIVERSITY OF TX MD ANDERSON CAN CTR, TX$208,800ZCA1
2018Collateral Deletions Expose Targetable Metabolic Vulnerabilities in the PTEN locus1R21CA226301-01MULLER, FLORIANUNIVERSITY OF TX MD ANDERSON CAN CTR, TX$208,800ZCA1
2018Identification and Targeting of Chemotherapy Refractory Small Cell Lung Cancer1R21CA226322-01DOWLATI, AFSHINCASE WESTERN RESERVE UNIVERSITY, OH$208,800ZCA1
2018Biological and Functional Significance of Lymphoma-Associated Macrophages in the Pathophysiology of Mantle Cell Lymphoma1R21CA222438-01A1FORD, RICHARD JUNIVERSITY OF TX MD ANDERSON CAN CTR, TX$208,800ZCA1
2018Co-operative roles for YAP1 and UCHL5 in cancer progression and therapy1R21CA231654-01RAI, KUNALUNIVERSITY OF TX MD ANDERSON CAN CTR, TX$208,800ZCA1
2018Targeting the MUC1-C Oncoprotein in Colitis-Associated Colorectal Cancer1R21CA229716-01KUFE, DONALD W.DANA-FARBER CANCER INST, MA$207,757ZCA1
2018Clonal Expansion of HTLV-1-Infected Cells and Adult T Cell Leukemia1R21CA216660-01A1GIAM, CHOU-ZENHENRY M. JACKSON FDN FOR THE ADV MIL/MED, MD$205,591ZCA1
2018A novel target to overcome chemoresistance in breast cancer1R21CA223389-01RINCON, MERCEDESUNIVERSITY OF VERMONT & ST AGRIC COLLEGE, VT$203,580ZCA1
2018Targeting IL-33 to boost immunotherapy of cancer1R21CA216574-01A1LU, BINFENGUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$203,580ZCA1
2018Development of a novel antiangiogenic drug for colon cancer by targeting neuropeptide Y receptors1R21CA216763-01A1SARKAR, CHANDRANIOHIO STATE UNIVERSITY, OH$203,363ZCA1
2018Analysis of HCC CTC Phenotype for Liver Transplant Candidate Selection1R21CA216807-01A1AGOPIAN, VATCHEUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$203,254ZCA1
2018Validation of a genomic signature that predicts for sub-optimal debulking of epithelial ovarian cancer1R21CA218973-01A1BIRRER, MICHAELUNIVERSITY OF ALABAMA AT BIRMINGHAM, AL$203,042ZCA1
2018Exploiting Drug Addiction to Improve the Efficacy of MAPK Pathway Targeted Therapy in BRAF and NRAS Mutant Melanoma1R21CA215910-01A1LO, ROGER SUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$202,819ZCA1
2018Explore Epithelial Mesenchymal Transition (EMT) in a Cooperative Model of Metastasis in Renal Cell Carcinoma1R21CA216770-01A1WU, LILYUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$202,819ZCA1
2018Selectively Targeting a PI3K subunit to overcome temozolomide resistance and treat recurrent glioblastoma1R21CA216768-01A1SHENG, ZHIVIRGINIA POLYTECHNIC INST AND ST UNIV, VA$202,343ZCA1
2018Development of a CF10 Predictive Gene Signature in CRC Organoids.1R21CA218933-01A1GMEINER, WILLIAM H.WAKE FOREST UNIVERSITY HEALTH SCIENCES, NC$202,275ZCA1
2018PET imaging of the tumor microenvironment for cancer detection1R21CA219899-01A1WADAS, THADDEUS J.WAKE FOREST UNIVERSITY HEALTH SCIENCES, NC$202,275ZCA1
2018The abscopal effect of nanosecond electric pulse tumor ablation and its enhancement for metastatic breast cancer1R21CA229939-01GUO, SIQIOLD DOMINION UNIVERSITY, VA$202,275ZCA1
2018Systems biology dissection of the road to T cell exhaustion within the tumor microenvironment to identify novel targets for tumor immunotherapy1R21CA216616-01A1HILL, ANN BOREGON HEALTH & SCIENCE UNIVERSITY, OR$200,970ZCA1
2018Determining how autophagy mediates resistance to cancer therapies1R21CA222455-01A1THOMAS, GEORGE VICTOROREGON HEALTH & SCIENCE UNIVERSITY, OR$200,970ZCA1
2018Exploiting chemoimmunotherapy strategies with genetically-engineered gd T cells1R21CA223300-01A1GOLDSMITH, KELLY CSPENCER, H TRENTEMORY UNIVERSITY, GA$200,637ZCA1
2018PSMA - Targeted Small-Molecule Drug Conjugates1R21CA223121-01A1BERKMAN, CLIFFORDWASHINGTON STATE UNIVERSITY, WA$199,665ZCA1
2018Novel molecular probes for imaging colorectal cancer1R21CA216657-01A1GRAY, BRIAN DAVIDLIU, ZHONGLINUNIVERSITY OF ARIZONA, AZ$199,183ZCA1
2018Targeting Musashi-2 (MSI2) regulation of EGFR and HER2 in lung cancer1R21CA223394-01A1BOUMBER, YANISRESEARCH INST OF FOX CHASE CAN CTR, PA$199,013ZCA1
2018AR-V7 Acetylation in Castration Resistant Prostate Cancer1R21CA223119-01A1LIU, WANGUOLSU HEALTH SCIENCES CENTER, LA$198,781ZCA1
2018An Exploratory Phase 1B Study to Assess the Effects of Merestinib on Bone Metastases in Subjects with Metastatic Breast Cancer1R21CA226489-01COHEN, ADAM LWELM, ALANA LUNIVERSITY OF UTAH, UT$198,686ZCA1
2018Identifying outcome mediators of calorie restriction mimetic use in renal cancer1R21CA223126-01NORIAN, LYSE AUNIVERSITY OF ALABAMA AT BIRMINGHAM, AL$193,793ZCA1
2018Novel ODC Inhibitor Phaseolotoxin in Neuroblastoma1R21CA216867-01A1BACHMANN, ANDRE SMICHIGAN STATE UNIVERSITY, MI$193,750ZCA1
2018Treatment of Acute Myeloid Leukemia with C2-Set Domain-Specific CD33 Antibodies1R21CA223409-01A1WALTER, ROLAND BRUNOFRED HUTCHINSON CANCER RESEARCH CENTER, WA$191,400ZCA1
2018Selective Androgen Receptor Modulators for the Treatment of Prostate Cancer1R21CA230138-01NELSON, PETER SFRED HUTCHINSON CANCER RESEARCH CENTER, WA$191,400ZCA1
2018Accurate Determination of Dose to Mobile Organs at Risk in Hypofractionated Ablative Radiotherapy for Locally Advanced Pancreatic Cancer1R21CA223304-01A1MAGERAS, GIKAS SSLOAN-KETTERING INST CAN RESEARCH, NY$189,706ZCA1
2018Molecular and Imaging Assessment of Fallopian Tube Health1R21CA229707-01BARTON, JENNIFER KEHLETUNIVERSITY OF ARIZONA, AZ$188,966ZCA1
2018Opportunities for targeted therapies generated by APOBEC3A activity in acute myeloid leukemia1R21CA230065-01WEITZMAN, MATTHEW D.CHILDREN'S HOSP OF PHILADELPHIA, PA$187,050ZCA1
2018Slow-cycling cells, therapy resistance and clinical implications in prostate cancer1R21CA218635-01A1TANG, DEAN G.ROSWELL PARK CANCER INSTITUTE CORP, NY$186,833ZCA1
2018Lymph liquid biopsy in cancer1R21CA230059-01GALANZHA, EKATERINA I.UNIV OF ARKANSAS FOR MED SCIS, AR$184,875ZCA1
2018Clinical Evaluation of an Implantable Lab-in-a-patient microdevice that measures in-situ response to therapies in advanced ovarian cancer1R21CA216796-01A1JONAS, OLIVERBRIGHAM AND WOMEN'S HOSPITAL, MA$183,736ZCA1
2018Immunomodulation by dietary protein restriction1R21CA221942-01A1PILI, ROBERTOINDIANA UNIVERSITY INDIANAPOLIS, IN$183,372ZCA1
2018Targeting the IL-6 - SPINK1 regulatory axis in ovarian clear cell carcinoma1R21CA226302-01RADISKY, EVETTE SMAYO CLINIC JACKSONVILLE, FL$183,322ZCA1
2018Targeting aberrant promoter DNA methylation for anticancer therapy1R21CA229727-01SHEN, LANLANBAYLOR COLLEGE OF MEDICINE, TX$182,700ZCA1
2018Adipose stromal cell targeting: a new approach to breast cancer treatment1R21CA216745-01A1KOLONIN, MIKHAIL GUENO, NAOTO T.UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON, TX$182,479ZCA1
2018Exploiting the immune microenvironment for radiotargeted destruction of leptomeningeal metastases1R21CA223325-01A1MINEA, RADUUNIVERSITY OF SOUTHERN CALIFORNIA, CA$179,438ZCA1
2018A genomewide discovery of chemoresistance-associated noncoding RNAs in human cancers1R21CA226303-01HE, TONG-CHUANUNIVERSITY OF CHICAGO, IL$176,175ZCA1
2018Type III Collagen as a suppressor of breast cancer progression and metastasis1R21CA216552-01A1VOLK, SUSAN WUNIVERSITY OF PENNSYLVANIA, PA$175,088ZCA1
2018Deployable Endoluminal Ultrasound Phased Array for Precision Treatment of Pancreatic Cancer1R21CA230120-01DIEDERICH, CHRIS JOHNUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$174,091ZCA1
2018Targeted Inhibition in Triple Negative Breast Cancer1R21CA229930-01NASSAR, NICOLASCINCINNATI CHILDRENS HOSP MED CTR, OH$172,913ZCA1
2018Ceramide Nanoliposomes in Combination with Focused Ultrasound for Treating Breast Cancer1R21CA230088-01KESTER, MARKPRICE, RICHARD J.UNIVERSITY OF VIRGINIA, VA$171,520ZCA1
2018Understanding the one-two punch: biomarkers of clinical response to a novel compensatory drug combination for metastatic TNBC1R21CA229951-01RADOVICH, MILANINDIANA UNIVERSITY INDIANAPOLIS, IN$171,281ZCA1
2018Targeted proteomics to aid in the management of patients with stage IA lung adeno1R21CA223335-01BORGIA, JEFFREY A.RUSH UNIVERSITY MEDICAL CENTER, IL$170,738ZCA1
2018DESI-MS detection of positive margins in kidney cancer1R21CA229933-01BROOKS, JAMES D.ZARE, RICHARD NSTANFORD UNIVERSITY, CA$170,738ZCA1
2018Contrast Enhanced Ultrasound Identification of Sentinel Nodes in Esophageal Cancer1R21CA218946-01A1LIU, JI-BINLOREN, DAVID ETHOMAS JEFFERSON UNIVERSITY, PA$169,650ZCA1
2018Exploring potential biomarkers predictive of response to ATR and CHK1 inhibitors1R21CA226317-01ZHANG, JUNRANOHIO STATE UNIVERSITY, OH$169,650ZCA1
2018OTUB1 as a Novel Therapeutic Target in Kidney Cancer by Deubiquitinating HIF2alpha1R21CA223675-01ZHANG, QINGUNIV OF NORTH CAROLINA CHAPEL HILL, NC$169,106ZCA1
2018Therapeutic potential of neutrophil protease inhibitors in colon cancer1R21CA216685-01A1OH, YOUNGMANVIRGINIA COMMONWEALTH UNIVERSITY, VA$168,563ZCA1
2018Genetically Modified Natural Killer Cells for Cancer Immunotherapy1R21CA216652-01A1MORIARITY, BRANDEN SUNIVERSITY OF MINNESOTA, MN$167,476ZCA1
2018NOVEL PAN-RALGEF INHIBITORS TO BLOCK PANCREATIC CANCER.1R21CA216722-01A1CLARK, GEOFFREY J.UNIVERSITY OF LOUISVILLE, KY$167,475ZCA1
2018Evaluation of IRAK4 As A Novel Therapeutic Target in Colorectal Cancer1R21CA223112-01LIM, KIAN HWASHINGTON UNIVERSITY, MO$165,844ZCA1
2018NCI Clinical and Translational Exploratory/ Developmental Studies1R21CA223371-01ZHENG, GUANGRONGUNIVERSITY OF FLORIDA, FL$165,844ZCA1
2018Investigation of a lectibody targeting tumor-associated oligomannose glycans1R21CA216447-01A1MATOBA, NOBUYUKIUNIVERSITY OF LOUISVILLE, KY$165,555ZCA1
2018Mastl, a novel therapeutic target in Colon Cancer1R21CA216746-01A1DHAWAN, PUNITAUNIVERSITY OF NEBRASKA MEDICAL CENTER, NE$165,391ZCA1
2018Identifying Therapeutic Vulnerabilities of c-MYC-driven Small Cell Lung Cancer1R21CA216504-01A1OLIVER, TRUDY GALEUNIVERSITY OF UTAH, UT$165,300ZCA1
2018New Strategy for Pancreatic Cancer Therapy1R21CA223429-01SOLHEIM, JOYCE CUNIVERSITY OF NEBRASKA MEDICAL CENTER, NE$165,210ZCA1
2018Clinical Evaluation of Primary Sampling Scatter Correction for Chest Tomosynthesis1R21CA216780-01A1LEE, YUEH ZUNIV OF NORTH CAROLINA CHAPEL HILL, NC$164,065ZCA1
2018Targeting MCJ/DNAJC15 and the mitochondrial electron transport chain in acute myeloid leukemia1R21CA223439-01DEGREGORI, JAMES VUNIVERSITY OF COLORADO DENVER, CO$163,459ZCA1
2018Discovery of Novel Drug Targets for Breast Cancer1R21CA222763-01FENG, XUUNIVERSITY OF ALABAMA AT BIRMINGHAM, AL$161,494ZCA1
2018Discovering adenosine kinase inhibitor targets in human neuroblastoma1R21CA218764-01A1LAN, MICHAEL SLSU HEALTH SCIENCES CENTER, LA$158,775ZCA1
2018A Chemopreventive Strategy Based on Edible MicroRNAs Produced in Plants1R21CA223353-01VANCE, VICKIUNIVERSITY OF SOUTH CAROLINA AT COLUMBIA, SC$156,514ZCA1
2018A DRUGGABLE CHROMATIN MODIFIER PATHWAY IN HCC1R21CA229927-01GUPTA, ROMIWAJAPEYEE, NARENDRAYALE UNIVERSITY, CT$103,485ZCA1
2018Analysis of T-cell antigen diversity by deep sequencing1R21CA226321-01HOLT, ROBERT ANDREWBRITISH COLUMBIA CANCER AGENCY, BC$29,235ZCA1
2017Discovery of Predictive Biomarkers for Cancer Therapies using Synthetic Lethality1R21CA218778-01SAMBUCETTI, LIDIA CSINHA, SUBARNASRI INTERNATIONAL, CA$277,285ZCA1
2017Candidate Gene Resequencing of Germline Multiple Myeloma1R21CA209533-01A1JOSEPH, VIJAISLOAN-KETTERING INST CAN RESEARCH, NY$256,165ZCA1
2017Overcoming immune suppression in cancer by targeting PSGL-1 in T cells used for adoptive transfer1R21CA216678-01BRADLEY, LINDA MAC PHERSONSANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE, CA$254,475ZCA1
2017Metabolomic Strategies to Identify Biomarkers of Chemoprevention in FAP Patients1R21CA217130-01NEKLASON, DEBORAH WOODSAMADDER, NILOY JEWELUNIVERSITY OF UTAH, UT$232,227ZCA1
2017Imaging VEGFR-1 in early metastatic lesions1R21CA216761-01BACKER, JOSEPH MLEWIS, JASON S.SLOAN-KETTERING INST CAN RESEARCH, NY$229,436ZCA1
2017Applying Chemical Biology to Target Deubiquitinating Enzymes in Lung Cancer1R21CA218787-01HAURA, ERIC B.H. LEE MOFFITT CANCER CTR & RES INST, FL$224,460ZCA1
2017Assessing the role of the DNA repair landscape in immune checkpoint therapy1R21CA216595-01SWEASY, JOANN B.YALE UNIVERSITY, CT$218,588ZCA1
2017Integrative genomic biomarkers for predicting response to immunotherapy in melanoma patients1R21CA218950-01HALABAN, RUTHYALE UNIVERSITY, CT$218,588ZCA1
2017Methylome characterization of bronchial epithelial projenitor cells1R21CA209436-01A1SPIVACK, SIMON DVIJG, JANALBERT EINSTEIN COLLEGE OF MEDICINE, INC, NY$216,172ZCA1
2017Prior-image-based CT reconstruction for low-dose lung cancer screening1R21CA219608-01STAYMAN, JOSEPH WEBSTERJOHNS HOPKINS UNIVERSITY, MD$213,368ZCA1
2017Inhibition of Stromal-Derived DKK3 to Enhance the Response of Pancreatic Cancer to Immunotherapy1R21CA218495-01HWANG, ROSA F.UNIVERSITY OF TX MD ANDERSON CAN CTR, TX$208,800ZCA1
2017Targeting VCAM1-a4b1 Signaling to Ameliorate Pulmonary Osteosarcoma Metastasis1R21CA218790-01HUANG, ALEX YEE-CHENCASE WESTERN RESERVE UNIVERSITY, OH$208,637ZCA1
2017Proteomics of Metastatic and Non-Metastatic Uveal Melanoma1R21CA209500-01A1CRABB, JOHN WCLEVELAND CLINIC LERNER COM-CWRU, OH$206,843ZCA1
2017RANK PATHWAY AND MAMMOGRAPHIC DENSITY IN MID-LIFE WOMEN1R21CA216515-01TORIOLA, ADETUNJI TWASHINGTON UNIVERSITY, MO$204,466ZCA1
2017Integrative signaling to increase efficacy of targeted therapies for triple negative breast cancer1R21CA218498-01MERAJVER, SOFIA DIANASOELLNER, MATTHEW BUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$203,580ZCA1
2017In vivo anti-PD1 gene therapy1R21CA204036-01A1LIEBER, ANDRE MICHAELUNIVERSITY OF WASHINGTON, WA$202,112ZCA1
2017Mammographic Density and Metabolic Genotyping for Predicting Cancer Prognosis1R21CA208938-01A1CHEN, JEON-HORSU, MIN-YING L.UNIVERSITY OF CALIFORNIA-IRVINE, CA$201,623ZCA1
2017Mechanism-based approach to combine histone deacetylase inhibitors with PARP inhibitors for therapy in AML1R21CA208937-01A1RASSOOL, FEYRUZ VIRGILIAUNIVERSITY OF MARYLAND BALTIMORE, MD$201,459ZCA1
2017Selective inhibition of Notch1 and ERBB3 by novel neutralizing antibodies to treat melanoma1R21CA218504-01BEDOGNI, BARBARAUNIVERSITY OF MIAMI SCHOOL OF MEDICINE, FL$201,459ZCA1
2017Targeting DNA Base Excision Repair in Acute Myeloid Leukemias1R21CA216551-01LLOYD, R. STEPHENOREGON HEALTH & SCIENCE UNIVERSITY, OR$200,970ZCA1
2017Directing Cancer Immunotherapy with Real-Time ImmunoPET1R21CA216648-01VIOLA, NERISSA THERESEWEI, WEI-ZENWAYNE STATE UNIVERSITY, MI$200,970ZCA1
2017Image-guided Dosimetry for Injectable Brachytherapy based on Elastin-like Polypeptide Nanoparticles1R21CA218940-01CAI, JINGYIN, FANG-FANGDUKE UNIVERSITY, NC$200,107ZCA1
2017Immunotherapeutic Approaches Targeting the MUC1-C Oncoprotein in Triple-Negative Breast Cancer1R21CA216553-01KUFE, DONALD W.DANA-FARBER CANCER INST, MA$199,501ZCA1
2017Novel model to study PDAC using normal human pancreatic tissue1R21CA218968-01WANG, PEIUNIVERSITY OF TEXAS HLTH SCIENCE CENTER, TX$199,013ZCA1
2017Development of personalized surgical algorithms for muscle-invasive bladder cancer patients1R21CA218976-01ABBOSH, PHILIPRESEARCH INST OF FOX CHASE CAN CTR, PA$199,013ZCA1
2017A germline variant that predicts and modulates the response of melanoma to immunotherapy1R21CA209309-01A1OSMAN, IMANNEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY$198,103ZCA1
2017Improving the radiation therapeutic ratio by inhibiting proinflammatory cytokines1R21CA205660-01A1KIM, JAE HOHENRY FORD HEALTH SYSTEM, MI$195,859ZCA1
2017Using Single Cell Analysis to identify therapeutic vulnerabilities in leptomeningeal melanoma metastases1R21CA216756-01FORSYTH, PETER ALEXANDERSMALLEY, KEIRANH. LEE MOFFITT CANCER CTR & RES INST, FL$187,050ZCA1
2017Sphingosine-1-phosphate receptor subtype 3 in oncogenic K-Ras mutant-driven lung adenocarcinoma1R21CA216650-01LEE, MENQ-JERWAYNE STATE UNIVERSITY, MI$179,988ZCA1
2017Understanding Uncertainties in Radiomics Studies1R21CA216572-01COURT, LAURENCE EUNIVERSITY OF TX MD ANDERSON CAN CTR, TX$174,000ZCA1
2017Specific induction of lethal autophagy in triple-negative breast cancer cells1R21CA208475-01A1CONNELL, TERRY D.STATE UNIVERSITY OF NEW YORK AT BUFFALO, NY$173,456ZCA1
2017Targeting cell metabolism for preventing and treating metastatic colon cancer1R21CA216604-01JIN, SHENGKAN VICTORRBHS-ROBERT WOOD JOHNSON MEDICAL SCHOOL, NJ$172,913ZCA1
2017De facto Target of Histone Deacetylase Inhibitors1R21CA215591-01SUN, ZHENGBAYLOR COLLEGE OF MEDICINE, TX$172,369ZCA1
2017Engineering Machinery Molecules to Visualize and Actuate Immunotherapy1R21CA209629-01A1WANG, YINGXIAOUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$168,563ZCA1
2017Memantine for Prevention of Cognitive Late Effects in Pediatric Patients Receiving Cranial Radiation Therapy for Low Grade Glioma1R21CA218625-01CONKLIN, HEATHER MST. JUDE CHILDREN'S RESEARCH HOSPITAL, TN$156,165ZCA1

Data: Grants.gov's daily extract and NIH's notice pages and award files, in ScienceGraph release conductgrants-2026-11-09-0.1.0. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.

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Your academic CV and NIH biosketch

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