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NIH funding notice PAR-16-229

Metabolic Reprogramming to Improve Immunotherapy (R21)

Closed on September 7, 2019.

Posted
May 6, 2016
Close date
September 7, 2019
Activity codes
Not stated on the notice page
Institutes taking part
Not stated on the notice page

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

Its page was not saved, so the notices it replaced are not known.

Who won it before

7 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $1,517,523 in first-year total cost, median $208,581.

Most frequent study sections

  1. Special Emphasis Panel[ZRG1 OTC-Y (55)]6
  2. Special Emphasis Panel[ZRG1 OTC-X (55)]1

Most frequent institutions

  1. UNIVERSITY OF CALIFORNIA LOS ANGELES2
  2. BETH ISRAEL DEACONESS MEDICAL CENTER1
  3. MASSACHUSETTS GENERAL HOSPITAL1
  4. SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE1
  5. UNIVERSITY OF ALABAMA AT BIRMINGHAM1
Competing awards under PAR-16-229 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2020Modulation of metabolism in TILs by the checkpoint inhibitor PSGL-11R21CA249353-01BRADLEY, LINDA MAC PHERSONSANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE, CA$273,488ZRG1
2020Optical control of T cell metabolism1R21CA242843-01A1KIM, MINSOOWOJTOVICH, ANDREW PHILLIPUNIVERSITY OF ROCHESTER, NY$215,985ZRG1
2019Target metabolic vulnerabilities of MDSCs to enhance cancer immunotherapy1R21CA227588-01A1ZHENG, BINMASSACHUSETTS GENERAL HOSPITAL, MA$208,581ZRG1
2019Targeting metabolic checkpoints in the tumor microenvironment to boost efficacy of anti-CTLA-41R21CA230475-01A1SHI, LEWIS ZHICHANGUNIVERSITY OF ALABAMA AT BIRMINGHAM, AL$193,793ZRG1
2018Directed Purinergic Signaling as Immunotherapy in Leukemia1R21CA221702-01A1AVIGAN, DAVID E.ROBSON, SIMON C.BETH ISRAEL DEACONESS MEDICAL CENTER, MA$228,375ZRG1
2018Metabolic MRI for quantifying aerobic glycolysis and immune function in gliomas1R21CA223757-01ELLINGSON, BENJAMIN M.UNIVERSITY OF CALIFORNIA LOS ANGELES, CA$202,204ZRG1
2018Role of ARID2 in the Regulation of Immune Checkpoint1R21CA228400-01SHUAI, KEUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$195,097ZRG1

Data: Grants.gov's daily extract and NIH's notice pages and award files, in ScienceGraph release conductgrants-2026-11-09-0.1.0. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.

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