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NIH funding notice PAR-17-094

Maximizing Investigators' Research Award (R35)

Closed on May 17, 2019.

Posted
December 21, 2016
Close date
May 17, 2019
Activity codes
R35
Institutes taking part
NIGMS

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

Its page names no earlier notice: it is new, or it does not say.

Replaced by PAR-19-367.

Who won it before

490 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $209,111,973 in first-year total cost, median $399,982.

Most frequent study sections

  1. Special Emphasis Panel[ZRG1 CB-J (55)]127
  2. Special Emphasis Panel[ZRG1 CB-B (55)]82
  3. Special Emphasis Panel[ZRG1 CB-Y (55)]68
  4. Special Emphasis Panel[ZRG1 CB-K (55)]65
  5. Special Emphasis Panel[ZRG1 CB-Q (55)]32

Most frequent institutions

  1. UNIVERSITY OF MICHIGAN AT ANN ARBOR21
  2. STANFORD UNIVERSITY15
  3. UNIV OF NORTH CAROLINA CHAPEL HILL13
  4. UNIVERSITY OF CALIFORNIA BERKELEY13
  5. UNIVERSITY OF WISCONSIN-MADISON13
Competing awards under PAR-17-094 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2020Chromosome organization and function in time and space: meiosis, mitosis and E.coli1R35GM136322-01KLECKNER, NANCY EHARVARD UNIVERSITY, MA$1,054,274ZRG1
2020Molecular and cellular mechanisms regulating actin dynamics1R35GM134895-01GOODE, BRUCE LBRANDEIS UNIVERSITY, MA$898,344ZRG1
2020Dissecting the Mechanisms of Regulation and Quality Control in Ribosome Assembly and the Consequences of their Failure1R35GM136323-01KARBSTEIN, KATRINSCRIPPS FLORIDA, FL$868,507ZRG1
2020Wnt Signaling and Vertebrate embryogenesis1R35GM134953-01HE, XIBOSTON CHILDREN'S HOSPITAL, MA$835,056ZRG1
2020Mining Actinomycetal Genomes for Natural Product Discovery and Biosynthesis1R35GM134954-01SHEN, BENSCRIPPS FLORIDA, FL$795,502ZRG1
2020Embryonic Emergence of Heterochromatin and Nuclear Supervision of Mitochondrial Genetics1R35GM136324-01O'FARRELL, PATRICK HUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$781,319ZRG1
2020The Mechanism and Regulation of Cytoplasmic and Ciliary Dyneins1R35GM136414-01YILDIZ, AHMETUNIVERSITY OF CALIFORNIA BERKELEY, CA$763,611ZRG1
2020Multiplex Imaging of Signaling Pathways in Cell Motility1R35GM136226-01HODGSON, LOUISALBERT EINSTEIN COLLEGE OF MEDICINE, NY$721,979ZRG1
2020Group II Intron and Related Reverse Transcriptases1R35GM136216-01LAMBOWITZ, ALAN M.UNIVERSITY OF TEXAS AT AUSTIN, TX$704,545ZRG1
2020Mechanisms of Cell Regulation and Manipulation by the Ubiquitin System1R35GM136325-01HOCHSTRASSER, MARK WYALE UNIVERSITY, CT$681,130ZRG1
2020DNA Damage & DNA Replication: a Complex Relationship1R35GM136278-01PETRINI, JOHN HJSLOAN-KETTERING INST CAN RESEARCH, NY$654,008ZRG1
2020Ribonucleoprotein Biogenesis and Epigenetic Gene Regulation1R35GM136435-01MATERA, A. GREGORYUNIV OF NORTH CAROLINA CHAPEL HILL, NC$652,834ZRG1
2020Regulation of proliferation and differentiation in the male germ line adult stem cell lineage1R35GM136433-01FULLER, MARGARET TSTANFORD UNIVERSITY, CA$641,756ZRG1
2020Mechanisms of Post-transcriptional Gene Regulation by PTB and Rbfox Proteins1R35GM136426-01BLACK, DOUGLAS LUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$636,492ZRG1
2020Photoredox Catalysis Applications in Organometallics and Chemical Biology1R35GM134897-01MACMILLAN, DAVID WPRINCETON UNIVERSITY, NJ$634,804ZRG1
2020Structure and Function of Pentameric Ligand-Gated Ion Channels1R35GM134896-01CHAKRAPANI, SUDHACASE WESTERN RESERVE UNIVERSITY, OH$617,925ZRG1
2020Control of actin filament networks by Arp2/3 complex and its regulators1R35GM136319-01NOLEN, BRADLEY JUNIVERSITY OF OREGON, OR$611,994ZRG1
2020Cytoskeleton, Nucleus and Integrin Recycling in Cell Migration1R35GM136403-01GUNDERSEN, GREGG GCOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$604,757ZRG1
2020Deciphering molecular details of cellular sugar transport and their roles in disease1R35GM135175-01ABRAMSON, JEFFREY SUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$602,657ZRG1
2020Building and shaping narrow epithelial tubes in C. elegans1R35GM136315-01SUNDARAM, MEERAUNIVERSITY OF PENNSYLVANIA, PA$602,201ZRG1
2020Phosphoinositide Signaling in the Cytosol and Nucleus1R35GM134955-01ANDERSON, RICHARD A.UNIVERSITY OF WISCONSIN-MADISON, WI$599,490ZRG1
2020Accurate Molecular Decision Making during Protein Biogenesis1R35GM136321-01SHAN, SHU-OUCALIFORNIA INSTITUTE OF TECHNOLOGY, CA$595,794ZRG1
2020The molecular mechanisms and functional significance of gene positioning1R35GM136419-01BRICKNER, JASON HAYSNORTHWESTERN UNIVERSITY, IL$594,543ZRG1
2020Macrophage Phenotypes and Tissue Repair1R35GM136228-01KOH, TIMOTHY JUNIVERSITY OF ILLINOIS AT CHICAGO, IL$590,382ZRG1
2020Regulation and Role of Phosphatidate Phosphatase in Lipid Metabolism1R35GM136128-01CARMAN, GEORGE M.RUTGERS, THE STATE UNIV OF N.J., NJ$587,290ZRG1
2020Epigenetic regulations of DNA and histone methylation and deMethylation: Structures and Mechanisms1R35GM134744-01CHENG, XIAODONGUNIVERSITY OF TX MD ANDERSON CAN CTR, TX$584,820ZRG1
2020Molecular and Cellular Dynamics in Mammalian Signal Transduction1R35GM136392-01AHN, NATALIE G.UNIVERSITY OF COLORADO, CO$575,251ZRG1
2020Genetic and Molecular Dissection of Wnt Pathway Activation1R35GM136233-01AHMED, YASMATHDARTMOUTH COLLEGE, NH$571,426ZRG1
2020Spatial Organization and Regulation of Bacterial Cellular Processes1R35GM136436-01XIAO, JIEJOHNS HOPKINS UNIVERSITY, MD$567,672ZRG1
2020Emergent mechanics of mammalian chromosome segregation1R35GM136420-01DUMONT, SOPHIEUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$567,440ZRG1
2020Reconstitution and biophysical study of chromosome segregation machinery1R35GM134842-01ASBURY, CHARLESUNIVERSITY OF WASHINGTON, WA$558,492ZRG1
2020Dissecting the impact of RNA on DNA replication and chromatin structure1R35GM134918-01SMITH, DUNCAN JNEW YORK UNIVERSITY, NY$550,793ZRG1
2020Integrative Genomic Analyses of Human Evolution and Adaptation in Africa1R35GM134957-01TISHKOFF, SARAH ANNEUNIVERSITY OF PENNSYLVANIA, PA$546,220ZRG1
2020Molecular basis of recognition in the Immunological Synapse1R35GM136357-01FISER, ANDRASALBERT EINSTEIN COLLEGE OF MEDICINE, NY$544,916ZRG1
2020In vivo regulation of the extracellular matrix1R35GM136236-01FAY, DAVID SUNIVERSITY OF WYOMING, WY$536,174ZRG1
2020Vibrational Spectroscopic Imaging to Unveil Hidden Signatures in Living Systems1R35GM136223-01CHENG, JI-XINBOSTON UNIVERSITY (CHARLES RIVER CAMPUS), MA$535,971ZRG1
2020Structure and Mechanism of G-proteins and cell adhesion proteins in regulation of cell growth and motility1R35GM134962-01CAMPBELL, SHARON LUNIV OF NORTH CAROLINA CHAPEL HILL, NC$532,801ZRG1
2020Mechanisms of Helicases, Translocases and SSB Proteins involved in Genome Maintenance1R35GM136632-01LOHMAN, TIMOTHY MWASHINGTON UNIVERSITY, MO$527,645ZRG1
2020Understanding the Evolution, Biology, and Molecular Mechanism of Argonaute Proteins1R35GM136275-01ZAMORE, PHILLIP DUNIV OF MASSACHUSETTS MED SCH WORCESTER, MA$509,771ZRG1
2020Integrative NMR and biophysical studies of fibrillar protein assemblies in health and disease1R35GM136431-01BAUM, JEAN SRUTGERS, THE STATE UNIV OF N.J., NJ$506,439ZRG1
2020Actin filament mechanics and branched network turnover1R35GM136656-01DE LA CRUZ, ENRIQUE MYALE UNIVERSITY, CT$503,021ZRG1
2020Molecular mechanisms that regulate vesicle formation and transport1R35GM134865-01AUDHYA, ANJONUNIVERSITY OF WISCONSIN-MADISON, WI$497,564ZRG1
2020Metabolic and purinergic immune regulation1R35GM136429-01JUNGER, WOLFGANG GBETH ISRAEL DEACONESS MEDICAL CENTER, MA$497,500ZRG1
2020A genetically encoded toolset to decipher the biology of post-translational modifications in the mammalian proteome1R35GM136437-01CHATTERJEE, ABHISHEKBOSTON COLLEGE, MA$489,524ZRG1
2020Nanoscale programing of cellular and physiological phenotypes1R35GM134864-01DOKHOLYAN, NIKOLAYPENNSYLVANIA STATE UNIV HERSHEY MED CTR, PA$477,979ZRG1
2020Determining how cell growth triggers cell division1R35GM134858-01SKOTHEIM, JAN MSTANFORD UNIVERSITY, CA$477,208ZRG1
2020Assembly Mechanisms of RNA-Protein Complexes for Genetic Control1R35GM136351-01WOODSON, SARAH A.JOHNS HOPKINS UNIVERSITY, MD$473,342ZRG1
2020New Catalytic Methods for the Synthesis of Complex Molecules1R35GM136330-01NICEWICZ, DAVID AUNIV OF NORTH CAROLINA CHAPEL HILL, NC$461,821ZRG1
2020A novel epigenetic mechanism in early embryogenesis1R35GM136346-01XIAO, ZHUO ANDREWYALE UNIVERSITY, CT$459,966ZRG1
2020Prions in the bacterial domain of life1R35GM136247-01HOCHSCHILD, ANNHARVARD MEDICAL SCHOOL, MA$454,260ZRG1
2020Fluorescence tools that illuminate biology and inspire translation1R35GM134963-01SCHEPARTZ, ALANNAUNIVERSITY OF CALIFORNIA BERKELEY, CA$453,649ZRG1
2020Molecular Mechanisms of Cell Cycle Control1R35GM136280-01BENANTI, JENNIFER AUNIV OF MASSACHUSETTS MED SCH WORCESTER, MA$452,453ZRG1
2020Development and Application of Nicotinic Acetylcholine Receptor Targeted Peptides for Biomedical Research1R35GM136430-01MCINTOSH, J MICHAELUNIVERSITY OF UTAH, UT$449,875ZRG1
2020Synthetic genetic systems for rapid biomolecular evolution in vivo1R35GM136297-01LIU, CHANG CUNIVERSITY OF CALIFORNIA-IRVINE, CA$441,794ZRG1
2020Mitochondrial respiratory chain disease mechanistic and therapeutic modeling1R35GM134863-01FALK, MARNI JCHILDREN'S HOSP OF PHILADELPHIA, PA$440,109ZRG1
2020Biochemical Investigations of Sugar-Modifying Enzymes1R35GM134643-01HOLDEN, HAZEL M.UNIVERSITY OF WISCONSIN-MADISON, WI$437,349ZRG1
2020Evolutionary and functional genomics of genetic novelties and expression adaptation in Drosophila1R35GM134930-01BEGUN, DAVID JUNIVERSITY OF CALIFORNIA AT DAVIS, CA$432,849ZRG1
2020Advanced approaches to protein structure prediction1R35GM136422-01ZHANG, YANGUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$431,776ZRG1
2020Control of Stem Cell Dynamics by a Niche at Steady-State and During Aging1R35GM136270-01DINARDO, STEPHEN FRANCISUNIVERSITY OF PENNSYLVANIA, PA$429,521ZRG1
2020Analytical pipelines for data and model integration: finding informed pathways for antimicrobial resistance control1R35GM134934-01LANZAS, CRISTINANORTH CAROLINA STATE UNIVERSITY RALEIGH, NC$427,994ZRG1
2020Structural Biology of the DNA Replication Stress Response1R35GM136401-01EICHMAN, BRANDT FVANDERBILT UNIVERSITY, TN$427,471ZRG1
2020Protein Mechanics Regulating Endocytic Clathrin Coat Nucleation1R35GM134855-01TRAUB, LINTON M.UNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$425,913ZRG1
2020Molecular mechanisms of neuronal plasticity1R35GM136363-01BLAU, JUSTINNEW YORK UNIVERSITY, NY$425,416ZRG1
2020Robust ultra-high sensitivity proteomic technologies for limited samples1R35GM136421-01IVANOV, ALEXANDER R.NORTHEASTERN UNIVERSITY, MA$424,032ZRG1
2020Molecular pathways connecting sleep, stress, metabolism and longevity1R35GM136237-01YOUNG, MICHAEL WARRENROCKEFELLER UNIVERSITY, NY$423,750ZRG1
2020Structure and Function of Protein Disorder in Membrane Trafficking and Organization1R35GM136686-01ELIEZER, DAVIDWEILL MEDICAL COLL OF CORNELL UNIV, NY$422,817ZRG1
2020Posttranslational Regulation of Cell Growth and Stress Responses1R35GM134883-01YU, YONGHAOUT SOUTHWESTERN MEDICAL CENTER, TX$421,951ZRG1
2020Regulation of gene expression by chromatin remodeling enzymes1R35GM136393-01IMBALZANO, ANTHONY NUNIV OF MASSACHUSETTS MED SCH WORCESTER, MA$420,427ZRG1
2020Specialized post-transcriptional mechanisms of gene expression in quiescence1R35GM134944-01VASUDEVAN, SHOBHAMASSACHUSETTS GENERAL HOSPITAL, MA$420,000ZRG1
2020Following mRNA from birth to death at single-molecule resolution1R35GM136296-01SINGER, ROBERT HALBERT EINSTEIN COLLEGE OF MEDICINE, NY$419,584ZRG1
2020New Synthetic Methods Enabled by Excited-State Redox Chemistry1R35GM134893-01KNOWLES, ROBERT RPRINCETON UNIVERSITY, NJ$419,493ZRG1
2020New catalytic methods for the rapid synthesis of N-unprotected chiral aziridines and amines1R35GM136373-01KURTI, LASZLORICE UNIVERSITY, TX$417,924ZRG1
2020Cell Fate Decisions in Epithelial Stem Cell Lineages1R35GM136348-01NYSTUL, TODDUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$417,466ZRG1
2020Cuproproteins for Redox Biology1R35GM136644-01CULOTTA, VALERIA CJOHNS HOPKINS UNIVERSITY, MD$414,288ZRG1
2020Probing transcriptional activation at the molecular level1R35GM136356-01MAPP, ANNA K.UNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$410,170ZRG1
2020Decoding the mechanisms of cell-cell fusion1R35GM136316-01CHEN, ELIZABETH HUT SOUTHWESTERN MEDICAL CENTER, TX$408,334ZRG1
2020Novel computational approaches to predict drug response and combination effects1R35GM136375-01XIE, YANGUT SOUTHWESTERN MEDICAL CENTER, TX$408,229ZRG1
2020Selective Nitrogen Atom Transfer for Applications in Biomedical Sciences1R35GM134926-01XU, HAOBRANDEIS UNIVERSITY, MA$406,250ZRG1
2020Molecular Probes for Biomembrane Recognition1R35GM136212-01SMITH, BRADLEY DUNIVERSITY OF NOTRE DAME, IN$405,709ZRG1
2020Membrane signaling protein modulation by lipids and drugs1R35GM136387-01ROSENBAUM, DANIELUT SOUTHWESTERN MEDICAL CENTER, TX$404,427ZRG1
2020Structural and functional understanding of bacterial defense and viral counter defense1R35GM134867-01WIEDENHEFT, BLAKE AMONTANA STATE UNIVERSITY - BOZEMAN, MT$404,074ZRG1
2020Exploring Wnt-Fzd signaling specificities1R35GM134961-01WILLERT, KARL HUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$403,819ZRG1
2020Metabolic signals regulating cell growth versus survival1R35GM136370-01TU, BENJAMIN PUT SOUTHWESTERN MEDICAL CENTER, TX$400,384ZRG1
2020Spatiotemporal interrogation of molecular mechanobiololgy at the cell-cell interface with nanotechnology tools1R35GM134948-01JUN, YOUNG-WOOKUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$399,963ZRG1
2020Structural biology of DNA damage response in chromatin1R35GM136262-01MER, GEORGESMAYO CLINIC ROCHESTER, MN$397,500ZRG1
2020Structural Studies of Nonribosomal Peptide Synthesis1R35GM136235-01GULICK, ANDREW MSTATE UNIVERSITY OF NEW YORK AT BUFFALO, NY$395,613ZRG1
2020Studies on Enzyme Activation and Novel Modes of Inhibition1R35GM134881-01RICHARD, JOHN PSTATE UNIVERSITY OF NEW YORK AT BUFFALO, NY$395,543ZRG1
2020Modeling mechanisms in cytokinesis, cell polarization and motility1R35GM136372-01VAVYLONIS, DIMITRIOSLEHIGH UNIVERSITY, PA$394,841ZRG1
2020Maintenance and Repair of the C. elegans Skin1R35GM134970-01CHISHOLM, ANDREW DUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$393,750ZRG1
2020Defining the Complosome in Human Cells, Tissues and Disease States1R35GM136352-01ATKINSON, JOHNWASHINGTON UNIVERSITY, MO$393,436ZRG1
2020Immune perception of bacterial pathogens in plants1R35GM136402-01COAKER, GITTA LAURELUNIVERSITY OF CALIFORNIA AT DAVIS, CA$392,500ZRG1
2020Molecular Basis of Centromere Specification and Inheritance1R35GM134920-01LI, FEINEW YORK UNIVERSITY, NY$392,150ZRG1
2020Unfolded protein response in the model species Arabidopsis thaliana1R35GM136637-01BRANDIZZI, FEDERICAMICHIGAN STATE UNIVERSITY, MI$391,250ZRG1
2020Structure prediction and in silico screening of protein-peptide interactions1R35GM136409-01ZOU, XIAOQINUNIVERSITY OF MISSOURI-COLUMBIA, MO$391,207ZRG1
2020Advances in bioanalysis1R35GM136334-01DOVICHI, NORMAN JUNIVERSITY OF NOTRE DAME, IN$390,417ZRG1
2020Molecular Mechanisms of Motility Deduced from in Vitro Reconstituted Microtubule- and Actin-Based Motor Complexes1R35GM136288-01TRYBUS, KATHLEEN MUNIVERSITY OF VERMONT & ST AGRIC COLLEGE, VT$390,000ZRG1
2020Inter- and intracellular mechanisms of circadian regulation1R35GM136400-01SOMERS, DAVID EOHIO STATE UNIVERSITY, OH$390,000ZRG1
2020Theoretical and Experimental Studies of the Population and Evolutionary Dynamics of Bacteria and Bacteriophage.1R35GM136407-01LEVIN, BRUCE RICHARDEMORY UNIVERSITY, GA$390,000ZRG1
2020The impact of natural selection and population structure on human genomic variation1R35GM136290-01COOP, GRAHAMUNIVERSITY OF CALIFORNIA AT DAVIS, CA$389,770ZRG1
2020Quorum sensing in Pseudomonas aeruginosa1R35GM136218-01GREENBERG, EVERETT PUNIVERSITY OF WASHINGTON, WA$388,750ZRG1
2020Contact-dependent signaling and DNA transposition in Burkholderia1R35GM136533-01COTTER, PEGGY AUNIV OF NORTH CAROLINA CHAPEL HILL, NC$388,750ZRG1
2020Mechanisms of Asymmetric Cell Division During Female Meiosis1R35GM136241-01MCNALLY, FRANCIS JUNIVERSITY OF CALIFORNIA AT DAVIS, CA$388,107ZRG1
2020Activities of yeast Ccr4-Not transcription factor complex1R35GM136353-01REESE, JOSEPH CPENNSYLVANIA STATE UNIVERSITY, THE, PA$387,297ZRG1
2020Regulation and Function of Integrated Stress Response1R35GM136331-01WEK, RONALD CINDIANA UNIVERSITY INDIANAPOLIS, IN$386,355ZRG1
2020Defining the Role of Aminoacyl-tRNA Synthetases in Human Health and Disease1R35GM136441-01ANTONELLIS, ANTHONYUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$385,624ZRG1
2020A model of repair: intercellular signaling and self-organization in plant regeneration1R35GM136362-01BIRNBAUM, KENNETH DAVIDNEW YORK UNIVERSITY, NY$385,584ZRG1
2020Signaling Mechanisms that Control Chromosome Segregation during Female Meiosis1R35GM136340-01SCHINDLER, KAREN ARUTGERS, THE STATE UNIV OF N.J., NJ$385,331ZRG1
2020Cellular and molecular mechanisms controlling sepsis-induced immunoparalyses state1R35GM134880-01BADOVINAC, VLADIMIR PUNIVERSITY OF IOWA, IA$385,226ZRG1
2020Molecular Tools to Illuminate Copper Transport and Homeostasis1R35GM136404-01FAHRNI, CHRISTOPH JGEORGIA INSTITUTE OF TECHNOLOGY, GA$385,115ZRG1
2020Auxin Response Factors as a model of transcriptional control1R35GM136338-01STRADER, LUCIADUKE UNIVERSITY, NC$383,120ZRG1
2020Translational Metabolomics in Critical Care1R35GM136312-01STRINGER, KATHLEEN AUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$382,707ZRG1
2020Developing novel technologies that ensure privacy and security in biomedical data science research1R35GM134927-01VAIDYA, JAIDEEPRUTGERS THE STATE UNIV OF NJ NEWARK, NJ$382,108ZRG1
2020Actin cytoskeleton from nucleus to organism1R35GM136384-01SOKAC, ANNAUNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN, IL$382,036ZRG1
2020Chromosome breakage, pairing and replication: impacts on cell fate and function1R35GM136389-01GOLIC, KENT GUNIVERSITY OF UTAH, UT$381,250ZRG1
2020Mechanisms of BER in Genomic Integrity and Epigenetic Regulation1R35GM136225-01DROHAT, ALEX CUNIVERSITY OF MARYLAND BALTIMORE, MD$380,493ZRG1
2020Coordinated Cytoskeletal Dynamics and Membrane Remodeling in Cellular Shape Change1R35GM135160-01GUPTON, STEPHANIEUNIV OF NORTH CAROLINA CHAPEL HILL, NC$380,281ZRG1
2020Functional causality in regulating cell morphogenesis1R35GM136428-01DANUSER, GAUDENZUT SOUTHWESTERN MEDICAL CENTER, TX$377,554ZRG1
2020Metal-Catalyzed Reactions for Organic Synthesis1R35GM136332-01SANFORD, MELANIE S.UNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$377,431ZRG1
2020Cross-kingdom RNA communications between plant and fungal pathogens1R35GM136379-01JIN, HAILINGUNIVERSITY OF CALIFORNIA RIVERSIDE, CA$377,219ZRG1
2020Regulation of the Native Protein Landscape by Molecular Chaperones1R35GM136660-01FREEMAN, BRIAN CUNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN, IL$376,865ZRG1
2020Chemical Biology Studies of the Dynamics and Inhibition of Peptidoglycan Biosynthesis1R35GM136365-01VANNIEUWENHZE, MICHAEL STRUSTEES OF INDIANA UNIVERSITY, IN$375,579ZRG1
2020Rare-event simulation and analysis for elucidating mechanisms of development and disease1R35GM136381-01DINNER, AARONUNIVERSITY OF CHICAGO, IL$375,065ZRG1
2020The Role of Secondary Interactions Relevant to Biological Reductions of Small Molecules1R35GM136360-01SZYMCZAK, NATHANIEL KOLNIKUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$373,731ZRG1
2020MIRA: Uncover Design Rules for Interaction and Assembly of Nature’s Molecular Machines1R35GM136411-01HAN, SONGIUNIVERSITY OF CALIFORNIA SANTA BARBARA, CA$373,539ZRG1
2020Leveraging Next-Generation Directed Evolution Platforms and Chemical Control of Proteostasis to Deliver Robust Biotechnologies and Illuminate Roles of Chaperone Networks in Protein Evolution1R35GM136354-01SHOULDERS, MATTHEW DONALDMASSACHUSETTS INSTITUTE OF TECHNOLOGY, MA$373,099ZRG1
2020Mechanisms of Spliceosome Assembly and Regulation1R35GM136261-01HOSKINS, AARON ANDREWUNIVERSITY OF WISCONSIN-MADISON, WI$371,971ZRG1
2020Analysis and engineering of cell signaling1R35GM136309-01SARKAR, CASIMUNIVERSITY OF MINNESOTA, MN$371,393ZRG1
2020Mechanisms of Human DNA Double-Strand Break Repair via Quantitative Single-Molecule Imaging1R35GM134947-01ROTHENBERG, ELINEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY$369,369ZRG1
2020Chromatin regulation of TCR locus V(D)J recombination1R35GM136284-01KRANGEL, MICHAEL SDUKE UNIVERSITY, NC$368,466ZRG1
2020Robust and efficient statistical inference methods for genomics1R35GM134922-01SONG, YUN SUNIVERSITY OF CALIFORNIA BERKELEY, CA$367,909ZRG1
2020Biochemistry, biology and diversity of Fic domains1R35GM134945-01ORTH, KIMUT SOUTHWESTERN MEDICAL CENTER, TX$367,219ZRG1
2020Yeast as a gateway to conquering protein misfolding diseases.1R35GM136229-01LIEBMAN, SUSAN WUNIVERSITY OF NEVADA RENO, NV$366,000ZRG1
2020Regulation of cell function by mechanical properties of biopolymer networks and lipid bilayers1R35GM136259-01JANMEY, PAUL AUNIVERSITY OF PENNSYLVANIA, PA$363,897ZRG1
2020Catalytic Oxidations for Pharmaceutical Synthesis1R35GM134929-01STAHL, SHANNON SUNIVERSITY OF WISCONSIN-MADISON, WI$363,331ZRG1
2020Characterizing the molecular mechanisms of centriole duplication, growth and maturation1R35GM136265-01ROGERS, GREGORY CHARLESUNIVERSITY OF ARIZONA, AZ$361,277ZRG1
2020Diet and Germline Progenitors1R35GM134876-01HUBBARD, E. JANE ALBERTNEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY$360,682ZRG1
2020Molecular Basis of Gene Regulation by Polycomb Repressive Complex 21R35GM136308-01LIU, XINUT SOUTHWESTERN MEDICAL CENTER, TX$359,251ZRG1
2020Molecular Biophysics of Mitochondrial Membranes1R35GM136415-01KIRICHOK, YURIYUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$357,691ZRG1
2020Mechanisms and functions of Shoc2-transduced cellular signals1R35GM136295-01GALPERIN, EMILIAUNIVERSITY OF KENTUCKY, KY$357,319ZRG1
2020New Methods and Strategies for the Synthesis and Selective Derivatization of Natural Products1R35GM136341-01NAGORNY, PAVELUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$356,719ZRG1
2020Understanding how heme and iron are metabolized by anaerobic commensal bacteria and host-microbiome communities1R35GM136390-01DUBOIS, JENNIFER LMONTANA STATE UNIVERSITY - BOZEMAN, MT$356,537ZRG1
2020Visualizing hierarchical processing of photic input to the circadian clock in vivo1R35GM136661-01DAVIDSON, ALEC JMOREHOUSE SCHOOL OF MEDICINE, GA$355,000ZRG1
2020Dynamics of the cellular interactome1R35GM136255-01BRUCE, JAMES EDWARDUNIVERSITY OF WASHINGTON, WA$353,710ZRG1
2020Molecular Mechanisms Underlying E-cadherin Mechanotransduction1R35GM136291-01DEMALI, KRIS AUNIVERSITY OF IOWA, IA$353,228ZRG1
2020Regulation of cellular plasticity and regeneration in Drosophila spermatogenesis1R35GM136665-01MATUNIS, ERIKA LJOHNS HOPKINS UNIVERSITY, MD$351,585ZRG1
2020Mechanisms of Spatial Organization in the Cytoplasm1R35GM136302-01GRIFFIN, ERIK EDARTMOUTH COLLEGE, NH$351,368ZRG1
2020Developing chemical-proteomic tools to investigate cysteine oxidation1R35GM134964-01WEERAPANA, ERANTHIEBOSTON COLLEGE, MA$349,518ZRG1
2020Protein-Induced Self-Assembly and Disassembly of Nanostructures Based on Oligo1R35GM136395-01THAYUMANAVAN, SANKARANUNIVERSITY OF MASSACHUSETTS AMHERST, MA$339,798ZRG1
2020MECHANISMS OF ARSENIC TRANSPORT AND BIOTRANSFORMATIONS1R35GM136211-01ROSEN, BARRY P.FLORIDA INTERNATIONAL UNIVERSITY, FL$339,632ZRG1
2020Regulation of the cell proliferation by CRL ubiquitin ligases1R35GM136250-01PAGANO, MICHELENEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY$339,000ZRG1
2020Metallacycle-mediated coupling in stereoselective synthesis1R35GM134725-01MICALIZIO, GLENN CDARTMOUTH COLLEGE, NH$338,250ZRG1
2020Phage Lysis1R35GM136396-01YOUNG, RYLAND FLETCHERTEXAS A&M AGRILIFE RESEARCH, TX$335,916ZRG1
2020Dynamics of the Bacterial Ribosome and Proteome1R35GM136412-01WILLIAMSON, JAMES RSCRIPPS RESEARCH INSTITUTE, THE, CA$333,860ZRG1
2020Genomic reprogramming in the early embryo1R35GM136298-01HARRISON, MELISSAUNIVERSITY OF WISCONSIN-MADISON, WI$327,657ZRG1
2020Mechanisms of nuclear size regulation1R35GM134885-01LEVY, DANIEL LEONUNIVERSITY OF WYOMING, WY$325,584ZRG1
2020Role of iRhoms and ADAM17 in EGFR and TNFalpha signaling1R35GM134907-01BLOBEL, CARL PETERHOSPITAL FOR SPECIAL SURGERY, NY$323,456ZRG1
2020Redox Regulation of Cysteine-Dependent Peroxidases and Signal Transduction Pathways1R35GM135179-01POOLE, LESLIE BWAKE FOREST UNIVERSITY HEALTH SCIENCES, NC$320,554ZRG1
2020Spatial control of membrane traffic by septin GTPases1R35GM136337-01SPILIOTIS, ELIAS TDREXEL UNIVERSITY, PA$316,824ZRG1
2020Contextual Factors and Psychological Mechanisms that Support or Disrupt Biomedical Career Pathways1R35GM136263-01LINNENBRINK-GARCIA, LISAMICHIGAN STATE UNIVERSITY, MI$314,704ZRG1
2020New Cooperative Catalysis Concepts for Asymmetric Synthesis1R35GM136440-01SCHEIDT, KARL ANORTHWESTERN UNIVERSITY, IL$314,085ZRG1
2020Structural/functional characterization of TGFβ superfamily signaling and regulation1R35GM134923-01THOMPSON, THOMAS BUNIVERSITY OF CINCINNATI, OH$312,530ZRG1
2020Regulation and Physiological Roles of Translational Fidelity1R35GM136213-01LING, JIQIANGUNIV OF MARYLAND, COLLEGE PARK, MD$305,874ZRG1
2020Beyond the tubulin code: Understanding how subunit diversity regulates the formation and function of microtubules1R35GM136253-01MOORE, JEFFREY KYLEUNIVERSITY OF COLORADO DENVER, CO$301,931ZRG1
2020Local and global regulation of bacterial growth1R35GM136221-01GOLEY, ERIN DJOHNS HOPKINS UNIVERSITY, MD$301,573ZRG1
2020Uncovering new approaches to manipulate and probe biochemical processes with spatial and temporal precision.1R35GM136367-01TUCKER, CHANDRA LUNIVERSITY OF COLORADO DENVER, CO$299,957ZRG1
2020Mechanisms of Copper Transport and Catalysis1R35GM136239-01BLACKBURN, NINIAN JOREGON HEALTH & SCIENCE UNIVERSITY, OR$299,673ZRG1
2020Role of sumoylation during stress signaling responses1R35GM136234-01GARDNER, RICHARD GEORGEUNIVERSITY OF WASHINGTON, WA$297,013ZRG1
2020tRNA in codon usage1R35GM134931-01HOU, YA-MINGTHOMAS JEFFERSON UNIVERSITY, PA$291,505ZRG1
2020Dissecting the mechanism of cell migration at the systems level1R35GM136345-01WANG, YU-LICARNEGIE-MELLON UNIVERSITY, PA$275,685ZRG1
2020Mechanism of Dmc1-mediated Meiotic Recombination in Budding Yeast1R35GM134942-01BISHOP, DOUGLAS KUNIVERSITY OF CHICAGO, IL$273,777ZRG1
2020Pharmacophore-Directed  Retrosynthesis Applied to Bioactive Natural Products Informing Mechanism of Action Studies1R35GM134910-01ROMO, DANIELBAYLOR UNIVERSITY, TX$273,570ZRG1
2020Structure-guided antibody targeting of pre-selected epitopes in amyloidogenic aggregates1R35GM136300-01TESSIER, PETER MUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$269,727ZRG1
2020GTPase Regulation of the Golgi Complex1R35GM136258-01FROMME, J CHRISTOPHERCORNELL UNIVERSITY, NY$265,107ZRG1
2020Redox Cofactor Diversity in Enzymatic Superfamilies1R35GM136294-01ELLIOTT, SEAN JBOSTON UNIVERSITY (CHARLES RIVER CAMPUS), MA$264,482ZRG1
2020GPCR anterograde trafficking1R35GM136397-01WU, GUANGYUAUGUSTA UNIVERSITY, GA$243,880ZRG1
2020New methods for computational modeling of RNA structures1R35GM134919-01CHEN, SHI-JIEUNIVERSITY OF MISSOURI-COLUMBIA, MO$240,392ZRG1
2020Illuminating the gene regulation underlying meiotic differentiation1R35GM134886-01BRAR, GLORIA ANNUNIVERSITY OF CALIFORNIA BERKELEY, CA$238,968ZRG1
2020Data Science Guided Organic Reaction Development1R35GM136271-01SIGMAN, MATTHEW SUNIVERSITY OF UTAH, UT$224,532ZRG1
2020Evolutionary innovations from host-microbe interactions1R35GM134936-01ELDE, NELS C.UNIVERSITY OF UTAH, UT$221,189ZRG1
2020Roles for Mismatch Repair Proteins in Maintaining Genome Stability1R35GM134872-01ALANI, ERIC E.CORNELL UNIVERSITY, NY$214,351ZRG1
2020Genomic Diversity and the Architectures of Adaptation and Incompatibility1R35GM136306-01POOL, JOHN EUNIVERSITY OF WISCONSIN-MADISON, WI$214,320ZRG1
2020Expanding the chemical biological tools for the detection and regulation of human and bacterial proteases1R35GM136286-01WOLAN, DENNIS WILLIAMSCRIPPS RESEARCH INSTITUTE, THE, CA$213,000ZRG1
2020Systematic elucidation of calcineurin phosphatase signaling in humans1R35GM136243-01CYERT, MARTHA S.STANFORD UNIVERSITY, CA$210,657ZRG1
2020Defining Genome Stability Mechanisms and their Regulation by SUMO and Ubiquitin1R35GM136273-01BODDY, MICHAEL NSCRIPPS RESEARCH INSTITUTE, THE, CA$201,166ZRG1
2020C. elegans gastrulation: A model for understanding apical constriction mechanisms1R35GM134838-01GOLDSTEIN, ROBERT PUNIV OF NORTH CAROLINA CHAPEL HILL, NC$179,432ZRG1
2020Mechanisms of Nuclear Migration1R35GM134859-01STARR, DANIEL AUNIVERSITY OF CALIFORNIA AT DAVIS, CA$152,408ZRG1
2020The functional organization of mammalian membranes1R35GM134949-01LEVENTAL, ILYAUNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON, TX$37,453ZRG1
2020Molecular mechanisms of nucleic acid machines1R35GM136313-01ENEMARK, ERICST. JUDE CHILDREN'S RESEARCH HOSPITAL, TN$22,534ZRG1
2019Genetic control of developmental timing1R35GM131741-01AMBROS, VICTORUNIV OF MASSACHUSETTS MED SCH WORCESTER, MA$857,178ZRG1
2019Functional Analysis of Epigenetic Complexes1R35GM131743-01KINGSTON, ROBERTMASSACHUSETTS GENERAL HOSPITAL, MA$772,993ZRG1
2019Probing the Function of Long Non-Coding RNAs in Differentiation1R35GM131833-01SPECTOR, DAVID LCOLD SPRING HARBOR LABORATORY, NY$768,000ZRG1
2019The mechanism and regulation of autophagy1R35GM131919-01KLIONSKY, DANIEL J.UNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$766,506ZRG1
2019Mechanisms of Ion Channels in Calcium Signaling1R35GM131921-01LONG, STEPHEN BARSTOWSLOAN-KETTERING INST CAN RESEARCH, NY$762,138ZRG1
2019Interrogating Protein Methyltransferases with Integrated Approaches1R35GM131858-01LUO, MINKUISLOAN-KETTERING INST CAN RESEARCH, NY$747,912ZRG1
2019Single-molecule visualization and mechanisms of DNA recombination and intersecting DNA transactions1R35GM131900-01KOWALCZYKOWSKI, STEPHEN CHARLESUNIVERSITY OF CALIFORNIA AT DAVIS, CA$746,558ZRG1
2019Designer Molecular Probes for Biomedical Applications1R35GM131907-01DMOCHOWSKI, IVAN JULIANUNIVERSITY OF PENNSYLVANIA, PA$727,444ZRG1
2019Molecular Basis for Membrane Lipid Homeostasis1R35GM131715-01REINISCH, KARIN MYALE UNIVERSITY, CT$727,054ZRG1
2019Systems-to-structure approaches for defining mitochondrial protein function1R35GM131795-01PAGLIARINI, DAVID JMORGRIDGE INSTITUTE FOR RESEARCH, INC., WI$702,082ZRG1
2019Polarity, growth, and morphogenesis of epithelia1R35GM130388-01BILDER, DAVIDUNIVERSITY OF CALIFORNIA BERKELEY, CA$697,649ZRG1
2019Regulation of cytokinesis1R35GM131799-01GOULD, KATHLEEN LVANDERBILT UNIVERSITY, TN$696,982ZRG1

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Data: Grants.gov's daily extract and NIH's notice pages and award files, in ScienceGraph release conductgrants-2026-11-09-0.1.0. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.

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