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NIH funding notice PAR-17-245

Research Projects to Enhance Applicability of Mammalian Models for Translational Research (R01)

Closed on March 12, 2020.

Posted
April 3, 2017
Close date
March 12, 2020
Activity codes
Not stated on the notice page
Institutes taking part
Not stated on the notice page

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

Its page was not saved, so the notices it replaced are not known.

Who won it before

33 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $18,039,293 in first-year total cost, median $557,766.

Most frequent study sections

  1. Special Emphasis Panel[ZRG1 OTC-C (56)]15
  2. Special Emphasis Panel[ZRG1 OTC-J (55)]10
  3. Special Emphasis Panel[ZRG1 OTC-N (55)]7
  4. Radiation Therapeutics and Biology Study Section[RTB]1

Most frequent institutions

  1. UNIVERSITY OF CALIFORNIA, SAN FRANCISCO3
  2. JOHNS HOPKINS UNIVERSITY2
  3. SLOAN-KETTERING INST CAN RESEARCH2
  4. UNIV OF MASSACHUSETTS MED SCH WORCESTER2
  5. UNIVERSITY OF TX MD ANDERSON CAN CTR2
Competing awards under PAR-17-245 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2021Leveraging canine spontaneous cancer to optimize the power of blood biopsy1R01CA255319-01KARLSSON, ELINORLONDON, CHERYL AUNIV OF MASSACHUSETTS MED SCH WORCESTER, MA$645,307ZRG1
2021Radiogenomic Credentialing of Head and Neck Cancer Models1R01CA243456-01A1SESHADRI, MUKUNDROSWELL PARK CANCER INSTITUTE CORP, NY$623,637ZRG1
2021Modeling myelodysplasia1R01CA253981-01A1GRIMES, H. LEIGHTONHALENE, STEPHANIECINCINNATI CHILDRENS HOSP MED CTR, OH$614,181ZRG1
2021Visualizing tumor heterogeneity in an immune intact and autochthonous mouse model of breast cancer1R01CA255372-01SNYDER, JOSHUA CLAIRDUKE UNIVERSITY, NC$365,458ZRG1
2020Mouse models of Kras-mutant colorectal cancer1R01CA246653-01A1HAIGIS, KEVINDANA-FARBER CANCER INST, MA$646,021ZRG1
2020Novel Transgenic Mouse Models Addressing Outstanding Translational Barriers in Antibody-Based Therapeutics1R01CA244327-01A1BOURNAZOS, STYLIANOSROCKEFELLER UNIVERSITY, NY$633,648ZRG1
2020Development of Advanced Preclinical Models for Pediatric Solid Tumors1R01CA243555-01A1HAUSSLER, DAVID HSWEET-CORDERO, ERIC ALEJANDROUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$616,057ZRG1
2020Advancing Precision Oncology in a Humanized, Fully Autologous Mouse Model1R01CA248277-01FIELDS, RYAN CFLAVELL, RICHARD AWASHINGTON UNIVERSITY, MO$612,841ZRG1
2020Expansion of Tumoroid Models for Precise Treatment of the Rectal Cancer Patient1R37CA248289-01SMITH, JESSE JOSHUASLOAN-KETTERING INST CAN RESEARCH, NY$611,246ZRG1
2020Rapid ex vivo biosensor cultures to assess dependencies in gastroesophageal cancer1R01CA248280-01BOEHM, JESSE SAMUELBROAD INSTITUTE, INC., MA$566,213ZRG1
2020Developing translationally-relevant genetically engineered mouse models of lung adenocarcinoma for investigations in cancer immunology1R01CA237037-01A1JOSHI, NIKHILYALE UNIVERSITY, CT$557,766ZRG1
2020Improving hepatocellular carcinoma mouse modeling by understanding the malignant potential and biology of liver cell subpopulations1R01CA251928-01ZHU, HAOUT SOUTHWESTERN MEDICAL CENTER, TX$542,616ZRG1
2020Modeling the Glioblastoma Microenvironment to Uncover Progression Mechanisms and Therapeutic Targets1R01CA247905-01BRAT, DANIEL JNORTHWESTERN UNIVERSITY AT CHICAGO, IL$522,787ZRG1
2020Rapid and flexible precision oncology mouse models of epithelial malignancies epithelial malignancies1R01CA233944-01A1LOWE, SCOTT W.SLOAN-KETTERING INST CAN RESEARCH, NY$488,090ZRG1
2020A Novel Adenoviral-Permissive, Immunocompetent Hamster Model to Evaluate Oncolytic Adenoviral Therapy for Glioblastoma1R01CA247970-01LANG, FREDERICK FUNIVERSITY OF TX MD ANDERSON CAN CTR, TX$454,473ZRG1
2020Myeloid cells and radiation-induced memory deficits in rodent glioma model: sex and age effects1R01CA246722-01A1GUPTA, NALINROSI, SUSANNAUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$370,054RTB
2020Development of novel metastatic mouse models that recapitulate the major immune contexts of human colon cancer1R01CA233983-01A1JACKS, TYLER E.MASSACHUSETTS INSTITUTE OF TECHNOLOGY, MA$332,226ZRG1
2019In Vivo Base Editing for Precision Oncology Models1R01CA229773-01A1DOW, LUKAS EDWARDWEILL MEDICAL COLL OF CORNELL UNIV, NY$646,960ZRG1
2019Mouse modeling of HPV infection1R01CA233486-01HUNG, CHIEN-FURODEN, RICHARD BRUCEJOHNS HOPKINS UNIVERSITY, MD$596,869ZRG1
2019Development of Novel Spontaneous HPV Cervicovaginal Carcinoma Models for Cancer Immunotherapy1R01CA237067-01WU, TZYY-CHOOUJOHNS HOPKINS UNIVERSITY, MD$596,869ZRG1
2019Polymerase-mediated ultramutagenesis and carcinogenesis in mice1R01CA237405-01CASTRILLON, DIEGO HUT SOUTHWESTERN MEDICAL CENTER, TX$552,634ZRG1
2019Highly penetrant and immunogenic mouse models of non-viral HCC that are suitable for evaluation of immune checkpoint inhibitors1R01CA234128-01KARIN, MICHAELUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$550,740ZRG1
2019Modeling Factors Associated with Risk of High-Grade Serous Carcinoma in Mice1R01CA226756-01A1CHO, KATHLEEN R.UNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$533,016ZRG1
2019Developing and credentialing patient-derived xenograft models to advance therapeutic approaches for chronic myelomonocytic leukemia1R37CA234021-01A1PADRON, ERICH. LEE MOFFITT CANCER CTR & RES INST, FL$514,636ZRG1
2019Conditionally Reprogrammed Cell Model for Castration-Resistant Prostate Cancer (CRPC)1R01CA222148-01A1LIU, XUEFENGGEORGETOWN UNIVERSITY, DC$493,219ZRG1
2019Definition of Immune Infiltrate Phenotype and DNA Damage Response Deficits Across Diverse Murine Mammary Carcinomas1R01CA239235-01BARCELLOS-HOFF, MARY HELENUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$486,710ZRG1
2019Credentialing a Genetically Engineered Clinically-Relevant Mouse Model of Multiple Myeloma1R01CA234181-01CHESI, MARTAMAYO CLINIC ARIZONA, AZ$379,725ZRG1
2018Transforming family dogs into a powerful and accessible model for human cancer1R37CA218570-01A1KARLSSON, ELINORUNIV OF MASSACHUSETTS MED SCH WORCESTER, MA$687,174ZRG1
2018Advancing treatment outcomes in malignant glioma by integrating immunotherapy and standard of care using genetically engineered mice that recapitulate molecular feature of human glioma1R01CA229784-01BOUSSIOTIS, VASSILIKI ACHAREST, ALAINBETH ISRAEL DEACONESS MEDICAL CENTER, MA$667,694ZRG1
2018Translational Applications in an Animal Model of Pancreatic Cystic Neoplasm and Cancer1R01CA218004-01A1MAITRA, ANIRBANUNIVERSITY OF TX MD ANDERSON CAN CTR, TX$597,598ZRG1
2018Development and Application of a Porcine Model of Pancreatic Cancer1R01CA222907-01A1CARLSON, MARK AUNIVERSITY OF NEBRASKA MEDICAL CENTER, NE$568,591ZRG1
2018Mammalian models for integrated metabolic and molecular profiling of malignant glioma1R01CA227089-01A1GRAEBER, THOMAS GNATHANSON, DAVID A.UNIVERSITY OF CALIFORNIA LOS ANGELES, CA$553,813ZRG1
2018Enhancing the dog as a model for human cancers: from genome sequence towards clinical trials.1R01CA225755-01A1LINDBLAD-TOH, KERSTINUPPSALA UNIVERSITY$410,424ZRG1

Data: Grants.gov's daily extract and NIH's notice pages and award files, in ScienceGraph release conductgrants-2026-11-09-0.1.0. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.

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