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NIH funding notice PAR-18-175

Pilot Clinical Trials for the Spectrum of Alzheimers Disease and Age-related Cognitive Decline (R01 Clinical Trial Optional)

Closed on July 26, 2018.

Posted
November 1, 2017
Close date
July 26, 2018
Activity codes
Not stated on the notice page
Institutes taking part
Not stated on the notice page

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

Its page was not saved, so the notices it replaced are not known.

Who won it before

20 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $36,601,494 in first-year total cost, median $763,493.

Most frequent study sections

  1. Special Emphasis Panel[ZRG1 BBBP-Z (55)]20

Most frequent institutions

  1. BETH ISRAEL DEACONESS MEDICAL CENTER2
  2. UNIVERSITY OF KANSAS MEDICAL CENTER2
  3. UNIVERSITY OF KENTUCKY2
  4. COGNITION THERAPEUTICS, INC.1
  5. EMORY UNIVERSITY1
Competing awards under PAR-18-175 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2019US POINTER Neuroimaging Ancillary Study1R01AG062689-01LANDAU, SUSAN MUNIVERSITY OF CALIFORNIA BERKELEY, CA$11,343,101ZRG1
2019A Seamless Phase 2A-B Randomized Double Blind Placebo Controlled Trial to Evaluate the Efficacy and Safety of PQ 912 in Patients with Early Alzheimer's Disease1R01AG061146-01FELDMAN, HOWARDUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$5,279,327ZRG1
2019A Pilot Electroencephalography (EEG) Study to Evaluate the Effect of CT1812 Treatment on Synaptic Activity in Subjects with Mild to Moderate Alzheimerʼs Disease1RF1AG058710-01A1CAGGIANO, ANTHONY OCOGNITION THERAPEUTICS, INC., PA$3,300,642ZRG1
2019Phase 2 Randomized, Double-Blind, Placebo-Controlled Clinical Trial of T3D-959 in Mild to Moderate Alzheimer's Disease Subjects1R01AG061122-01DIDSBURY, JOHNT3D THERAPEUTICS, INC., NC$2,292,799ZRG1
2019A randomized, double blind, placebo-controlled study to evaluate the impact of Nilotinib treatment on safety, tolerability, pharmacokinetics and biomarkers in Dementia with Lewy Bodies (DLB)1R01AG062463-01MOUSSA, CHARBELGEORGETOWN UNIVERSITY, DC$1,417,321ZRG1
2019First-in-human SAD & MAD trials for MW151, a novel Alzheimer's disease drug candidate that attenuates proinflammatory cytokine dysregulation1R01AG061898-01VAN ELDIK, LINDA JWATTERSON, DANIEL MARTINUNIVERSITY OF KENTUCKY, KY$1,403,277ZRG1
2019Efficacy of Adapted Tai Ji Quan to Slow Cognitive Decline in Older Adults1R01AG059546-01A1LI, FUZHONGOREGON RESEARCH INSTITUTE, OR$782,329ZRG1
2019Evaluating the disease-modifying potential of a sleep intervention for Alzheimer's Disease outcomes1R01AG062673-01DENBURG, NATALIE LUNIVERSITY OF IOWA, IA$768,747ZRG1
2019Primary Prevention of Alzheimer's disease: Examining the effects of cognitive behavioral therapy on cognitive function and amyloid-beta in older adults with symptoms of insomnia1R01AG058530-01A1SIENGSUKON, CATHERINE FUNIVERSITY OF KANSAS MEDICAL CENTER, KS$763,979ZRG1
2019Safety and modulation of ABCC9 pathways by nicorandil for the treatment of hippocampal sclerosis of aging (SMArT–HS)1R01AG061111-01JICHA, GREGORY ANELSON, PETER T.UNIVERSITY OF KENTUCKY, KY$763,006ZRG1
2019A Novel Computerized Cognitive Stress Test Designed for Clinical Trials in Early Alzheimer's: Relationship with Multimodal Imaging Biomarkers in Diverse Cultural Groups1R01AG061106-01LOEWENSTEIN, DAVIDUNIVERSITY OF MIAMI SCHOOL OF MEDICINE, FL$748,976ZRG1
2019(-)-Phenserine inhibition of neuronal death in Alzheimer’s disease and developing brain-labeled plasma exosomes assays as biomarkers for a phenserine phase 1b ascending dose trial1R01AG062687-01BALLARD, CLIVESCHNEIDER, LON SUNIVERSITY OF SOUTHERN CALIFORNIA, CA$725,263ZRG1
2019Validation and Mechanistic Interrogation of Metabolism Targeting for AD1R01AG060733-01A1SULLIVAN, DEBRA KSWERDLOW, RUSSELL H.UNIVERSITY OF KANSAS MEDICAL CENTER, KS$721,830ZRG1
2019Reducing African Americans' Alzheimer's Disease Risk Through Exercise (RAATE)1R01AG062200-01CARMICHAEL, OWEN T.NEWTON, ROBERT LEELSU PENNINGTON BIOMEDICAL RESEARCH CTR, LA$715,602ZRG1
2019Reducing Risk of Dementia through De-prescribing (R2D2)1R01AG061452-01CAMPBELL, NOLL L.PURDUE UNIVERSITY, IN$691,971ZRG1
2019Gamma Induction for Amyloid Clearance in Alzheimer’s Disease1R01AG060981-01SANTARNECCHI, EMILIANOBETH ISRAEL DEACONESS MEDICAL CENTER, MA$649,289ZRG1
2019Partnered Rhythmic Rehabilitation for Enhanced Motor-Cognition in Prodromal Alzheimer's Disease1R01AG062691-01HACKNEY, MADELEINE EVEEMORY UNIVERSITY, GA$628,597ZRG1
2019Influence of Strategy Training on Disability for Older Adults with Mild Cognitive Impairment1R01AG056351-01A1RODAKOWSKI, JULEENUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$619,155ZRG1
2019Treating hyperexcitability in Alzheimer’s disease with levetiracetam to improve brain function and cognition1R01AG060987-01SHAFI, MOUHSINBETH ISRAEL DEACONESS MEDICAL CENTER, MA$571,143ZRG1
2018A Randomized Controlled Trial of Electroconvulsive Therapy plus Usual Care versus Simulated-ECT plus Usual Care for the Acute Management of Severe Agitation in Alzheimer's Dementia (ECT-AD)1R01AG061100-01FORESTER, BRENT PETERPETRIDES, GEORGIOSMCLEAN HOSPITAL, MA$2,415,140ZRG1

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PAR-18-175: Pilot Clinical Trials for the Spectrum of Alzheimers Disease and Age-related Cognitive Decline (R01 Clinical Trial Optional) | ScienceDex | ConductScience