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NIH funding notice PAR-18-207

NIBIB Trailblazer Award for New and Early Stage Investigators (R21 Clinical Trial Optional)

Closed on January 7, 2020.

Posted
November 17, 2017
Close date
January 7, 2020
Activity codes
Not stated on the notice page
Institutes taking part
Not stated on the notice page

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

Its page was not saved, so the notices it replaced are not known.

Who won it before

93 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $26,967,719 in first-year total cost, median $228,836.

Most frequent study sections

  1. Imaging Technology Development Study Section[ITD]8
  2. Biomedical Computing and Health Informatics Study Section[BCHI]7
  3. Bioengineering, Technology and Surgical Sciences Study Section[BTSS]6
  4. Instrumentation and Systems Development Study Section[ISD]6
  5. Bioengineering of Neuroscience, Vision and Low Vision Technologies Study Section[BNVT]5

Most frequent institutions

  1. STANFORD UNIVERSITY5
  2. BOSTON UNIVERSITY (CHARLES RIVER CAMPUS)4
  3. UNIVERSITY OF CALIFORNIA, SAN DIEGO4
  4. TEXAS ENGINEERING EXPERIMENT STATION3
  5. UNIVERSITY OF CALIFORNIA AT DAVIS3
Competing awards under PAR-18-207 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2020Machine learning for fast motion compensated quantitative abdominal DCE-MRI1R21EB029627-01KURUGOL, SILABOSTON CHILDREN'S HOSPITAL, MA$708,000EITA
2020A Soft Robotic Sleeve to Enable Safer and Easier Colonoscopy Procedures1R21EB029154-01AIHARA, HIROYUKIRUSSO, SHEILABOSTON UNIVERSITY (CHARLES RIVER CAMPUS), MA$682,685BTSS
2020Imaging of Metabolic Bone Response due to Localized Mechanical Loading1R21EB030180-01KOGAN, FELIKSSTANFORD UNIVERSITY, CA$630,800EITA
2020Tension-Sensitive Drug Release System to Enhance Targeting Selectivity1R21EB029677-01CHEN, YUNJOHNS HOPKINS UNIVERSITY, MD$609,641GDD
2020Enabling advanced endovascular beating-heart procedures through soft robotics1R21EB028363-01A1RANZANI, TOMMASOBOSTON UNIVERSITY (CHARLES RIVER CAMPUS), MA$607,730BTSS
2020BehaviorSight: Privacy enhancing wearable system to detect health risk behaviors in real-time.1R21EB030305-01ALSHURAFA, NABILNORTHWESTERN UNIVERSITY AT CHICAGO, IL$606,713ZRG1
20203D printed resonant-enhanced sensors (PRES) for total joint arthroplasties1R21EB029563-01KONG, YONG LINUNIVERSITY OF UTAH, UT$605,800ISD
2020ULTRASOUND AS A MECHANOTHERAPY FOR ENDOTHELIAL CELL DYSFUNCTION1R21EB028960-01PEDRIGI, RYAN MICHAELUNIVERSITY OF NEBRASKA LINCOLN, NE$602,769AICS
2020Mechanical Augmentation of the Diaphragm for End-Stage Respiratory Failure1R21EB028414-01A1ROCHE, ELLEN T.MASSACHUSETTS INSTITUTE OF TECHNOLOGY, MA$602,618BTSS
2020Novel Multi-Depth Two-Photon Microscope for Measuring Neuronal Network Plasticity1R21EB029139-01A1SHTRAHMAN, MATTHEWUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$591,330ZRG1
2020Refreshable Biosensors for Continuous Renal Function Monitoring1R21EB029064-01A1TIAN, LIMEITEXAS ENGINEERING EXPERIMENT STATION, TX$589,100ISD
2020In Silico Mapping of the Heart-Brain Embolus Transport Pathway for Stroke1R21EB029736-01MUKHERJEE, DEBANJANUNIVERSITY OF COLORADO, CO$584,301BCHI
2020MRI-Controllable Microscale Electronics for Minimally-Invasive Wireless Bio-Sensors and Bio-Actuators1R21EB030244-01MONGE, MANUELUNIVERSITY OF SOUTHERN CALIFORNIA, CA$574,410ITD
2020A New J-Resolved MRSI Framework for Whole-Brain Simultaneous Metabolite and Neurotransmitter Mapping1R21EB029076-01A1LAM, FANUNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN, IL$565,546EITN
2020Next-Generation Ultrasound Localization Microscopy1R21EB030072-01SONG, PENGFEIUNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN, IL$565,346ITD
2020A Transfer Learning Framework for Creating Subject-Specific Musculoskeletal Models of the Hand1R21EB030068-01NICHOLS, JENNIFER A.UNIVERSITY OF FLORIDA, FL$560,939MRS
2020Decoding inner speech: An AI approach to transcribing thoughts via EEG & EMG1R21EB029607-01A1CORTES-BRIONES, JOSE AYALE UNIVERSITY, CT$523,600BCHI
2020Development of Molecular Microbubble Probes and Ultrasound-Guidance in Immunotherapeutic Strategies1R21EB029046-01A1EL KAFFAS, AHMEDSTANFORD UNIVERSITY, CA$315,823IGIS
2020Activity-Based Aptamers as Bioimaging Tools for Probing Organics, Inorganics, and Enzymes1R21EB029548-01IZGU, ENVER CRUTGERS, THE STATE UNIV OF N.J., NJ$306,754EBIT
2020Understanding the relationships between FUS-BBB opening, neuroinflammation and the neurovascular response1R21EB030173-01ANGOLANO, CLEIDETODD, NICHOLAS E.BRIGHAM AND WOMEN'S HOSPITAL, MA$301,319IGIS
2020Fine-grained spatial information extraction for radiology reports1R21EB029575-01ROBERTS, KIRK EDWARDUNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON, TX$271,250BCHI
2020Passive antennas for improved image quality in transcranial MR-guided focused ultrasound1R21EB029639-01YAN, XINQIANGVANDERBILT UNIVERSITY MEDICAL CENTER, TN$266,890ITD
2020Label-free measurement of blood lipids with hyperspectral short-wave infrared spatial frequency domain imaging to improve cardiovascular disease risk prediction and treatment monitoring1R21EB030197-01ROBLYER, DARREN MICHAELBOSTON UNIVERSITY (CHARLES RIVER CAMPUS), MA$266,712ISD
2020The Development of Radiolabeled Positional isomers of [11C]Pyruvate for Imaging Cancer Metabolism1R21EB029649-01A1KELLY, JAMESWEILL MEDICAL COLL OF CORNELL UNIV, NY$251,397IPCA
2020Development of a wound-on-chip model to study stromal-epithelial interactions during tissue repair1R21EB028491-01A1EYCKMANS, JEROENBOSTON UNIVERSITY (CHARLES RIVER CAMPUS), MA$247,500MTE
2020Data-driven Head Motion Correction in PET Imaging Using Deep Learning1R21EB028954-01LU, YIHUANONOFREY, JOHN AARONYALE UNIVERSITY, CT$243,150ITD
2020Breast Cancer Detection and Imaging using Analyzer-less X-ray Interferometry1R21EB029026-01A1DEY, JOYONILOUISIANA STATE UNIV A&M COL BATON ROUGE, LA$243,128ITD
2020Chimeric Antigen Receptor (CAR) Directed T-regulatory Cell Therapy for Aortic Aneurysm1R21EB029614-01OSKOWITZ, ADAMUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$241,876BTSS
2020Development and Validation of a Robust and Modular Host: Guest-based Pretargeting Platform1R21EB027982-01A1HOUGHTON, JACOBSTATE UNIVERSITY NEW YORK STONY BROOK, NY$239,250IPCA
2020Histotripsy as a novel limb salvage treatment and immunotherapy for osteosarcoma1R21EB030182-01TUOHY, JOANNEVIRGINIA POLYTECHNIC INST AND ST UNIV, VA$237,547IGIS
2020De novo design of generalizable allosteric modulators and peptide ligands for G protein coupled receptors1R21EB028342-01A1BAHL, CHRISTOPHER DAVIDINSTITUTE FOR PROTEIN INNOVATION, INC., MA$232,750MSFD
2020The Nanoneedle Net: A flexible and transparent 3D nanoelectrode array for mapping intracellular dendritic dynamics at the cortical surface1R21EB029740-01JAYANT, KRISHNAPURDUE UNIVERSITY, IN$226,824BNVT
2020Harnessing the biophysics of multivalent nanoparticle adhesion to control cell targeting and internalization1R21EB027883-01A1HAUN, JERED BRACKSTONUNIVERSITY OF CALIFORNIA-IRVINE, CA$224,790NANO
2020Adhesive Transient Strain Sensors for Monitoring Post-Cardiotomy Hemodynamics1R21EB028418-01A1HALBREINER, MICHAEL SCOTTALLEGHENY-SINGER RESEARCH INSTITUTE, PA$221,740BTSS
2020Imaging enzyme activity by Overhauser-enhanced MRI1R21EB028553-01A1DRIESSCHAERT, BENOITWEST VIRGINIA UNIVERSITY, WV$218,640EBIT
2020Photodynamic Priming for Bidirectional Modulation of Drug Transport Across the Blood-Brain Tumor Barrier1R21EB028508-01A1HUANG, HUANG CHIAOUNIV OF MARYLAND, COLLEGE PARK, MD$203,530IGIS
2020Generating morphogen gradients to engineer human integumentary organoids1R21EB028970-01A1ABACI, HASAN ERBILCOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$202,500MTE
2020Improving Biomaterial Implant Tolerance with Damage-Associated Molecular Pathway (DAMP) Molecule Attachment1R21EB028971-01A1EWALD, SARAH E.GRIFFIN, DONALD RICHIERIUNIVERSITY OF VIRGINIA, VA$197,978BMBI
2020Novel Protease-Activatable Tracers for Targeted Imaging of Chemerin Receptor in Inflammation1R21EB027871-01A1TAVAKOLI, SINAUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$195,625IPCA
2020Task-aware and Autonomous Robotic C-arm Servoing for Flouroscopy-guided Interventions1R21EB028505-01A1UNBERATH, MATHIASJOHNS HOPKINS UNIVERSITY, MD$193,784IGIS
2020Chemical tools to decode nuclear lamina-ome1R21EB028425-01A1LI, BINGBINGOREGON HEALTH & SCIENCE UNIVERSITY, OR$192,500NCSD
2020Nanoparticle-mediated Histotripsy (NMH) for Noninvasive and Targeted Ablation of Metastatic Breast Cancer1R21EB027979-01A1VLAISAVLJEVICH, ELIVIRGINIA POLYTECHNIC INST AND ST UNIV, VA$190,371NANO
2020Novel Quantitative MRI Techniques for the Assessment of Cardiac Fibrosis without Gadolinium Contrast1R21EB028369-01A1AKCAKAYA, MEHMETUNIVERSITY OF MINNESOTA, MN$187,319ZRG1
2020A Closed Loop Control System with Live Cells in the Loop1R21EB028489-01A1SORRENTINO, FRANCESCOUNIVERSITY OF NEW MEXICO, NM$180,040ISD
2020Single-Shot Quantitative X-ray Imaging for Interventional Procedures1R21EB030080-01WANG, ADAM SSTANFORD UNIVERSITY, CA$157,700ITD
2020Development of An Optoelectronically Active Bioink1R21EB030257-01YU, CUNJIANGUNIVERSITY OF HOUSTON, TX$107,759BMBI
2019Delivery of Precision Acoustic Fields to Penetrating Neural Implants to Improve Longevity and Performance of the Neural Interface1R21EB028055-01TIRKO, NATASHA NOELACTUATED MEDICAL, INC., PA$328,373BNVT
2019Leveraging Artificial-Intelligence to Profile and Enhance Phenotypic Plasticity for Second Injury Prevention: An Innovative Precision Medicine Platform to Revolutionize Injury Care1R21EB027865-01KIEFER, ADAMUNIV OF NORTH CAROLINA CHAPEL HILL, NC$326,700BCHI
2019Enabling Technology for a Biomimetic Artificial Retinal Chemical Synapse Chip1R21EB028069-01SAGGERE, LAXMANUNIVERSITY OF ILLINOIS AT CHICAGO, IL$324,005BNVT
2019Aptamer-Modified POSH Inhibitor Micelles as a Novel Leukemia Treatment Modality1R21EB026560-01A1DANIELS, MARK A.ULERY, BRET DANIELUNIVERSITY OF MISSOURI-COLUMBIA, MO$298,013DMP
2019Wave-Cam: A novel micro-radar imaging array for non-rigid motion estimation in hybrid medical imaging1R21EB027250-01A1LINDSAY, CLIFFORDUNIV OF MASSACHUSETTS MED SCH WORCESTER, MA$280,629CTIS
2019Non-invasive Estimation of the Arterial Input Function in PET Studies using Whole-Body Physiological Models1R21EB026759-01A1GALLEZOT, JEAN-DOMINIQUEYALE UNIVERSITY, CT$251,250ITD
2019Molecularly targeted photothermal ablation to enhance the therapeutic efficacy of immunomodulatory therapies in hepatocellular carcinoma1R21EB026089-01A1SHETH, RAHUL ANILUNIVERSITY OF TX MD ANDERSON CAN CTR, TX$240,000RTB
2019Point-of-Care Quantitation of Sputum Neutrophil Elastase Activity in Chronic Airway Disease1R21EB028485-01HALL, DREW ALEXANDERO'DONOGHUE, ANTHONY JOHNUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$236,250ISD
2019PET-enabled Dual-energy CT1R21EB027346-01A1WANG, GUOBAOUNIVERSITY OF CALIFORNIA AT DAVIS, CA$235,500BMIT
2019Mobile Device-Based Congestion Prediction for Reducing Hospitalizations in Patients with Concomitant Heart Failure and Atrial Fibrillation1R21EB027276-01A1SAEED, MOHAMMEDUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$235,127BTSS
2019PSMA activatable MRI contrast agents to improve the detection of prostate cancer1R21EB028348-01LOENING, ANDREAS MARKUSSTANFORD UNIVERSITY, CA$234,816ZRG1
2019Painting Vasculature with Photosensitive Liposomes1R21EB027812-01A1ZOLDAN, JANETAUNIVERSITY OF TEXAS AT AUSTIN, TX$233,655BMBI
2019Input encoding in T-cell receptor signaling1R21EB027327-01KUEH, HAO YUANUNIVERSITY OF WASHINGTON, WA$233,250MABS
2019Tumor-targeted delivery and cell internalization of theranostic gadolinium nanoparticles for image-guided nanoparticle-enhanced radiation therapy1R21EB026553-01A1LIU, WUSTANFORD UNIVERSITY, CA$230,298RTB
2019Deep Learning and Fluid Dynamics Based Phenotyping of Expiratory Central Airway Collapse1R21EB027891-01BHATT, SURYA P.RAGHAV, VRISHANKUNIVERSITY OF ALABAMA AT BIRMINGHAM, AL$226,659BMIT
2019Expanding the Therapeutic Potential of the Alpha Emitter Radium-2231R21EB027282-01A1WILSON, JUSTIN JCORNELL UNIVERSITY, NY$223,112IPCA
2019Novel ultra-fast photodetectors for near reconstruction-less time-of-flight positron emission tomography1R21EB028398-01ARIÑO ESTRADA, GERARDUNIVERSITY OF CALIFORNIA AT DAVIS, CA$222,808ITD
2019Recording central blood flow velocity waveform by conformal ultrasonic devices1R21EB027303-01A1XU, SHENGUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$220,222HM
2019Automated, model-guided phenotyping to identify metabolite/gene/microbe interactions1R21EB027396-01JENSEN, PAUL ANTHONYUNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN, IL$219,161MABS
2019Content-based MR-TRUS Fusion without Tracking1R21EB028001-01YAN, PINGKUNRENSSELAER POLYTECHNIC INSTITUTE, NY$217,513BMIT
2019Autonomous Pain Recognition in Non-Verbal and Critically Ill Patients1R21EB027344-01RASHIDI, PARISAUNIVERSITY OF FLORIDA, FL$215,635BCHI
2019Super resolution label-free imaging in highly scattering bone1R21EB027802-01MORTENSEN, LUKE J.UNIVERSITY OF GEORGIA, GA$213,000CMT
2019Modeling atypical hemolytic uremic syndrome with hydrogel-based microvasculature-on-chip technologies1R21EB028519-01CHONAT, SATHEESHQIU, YONGZHIEMORY UNIVERSITY, GA$209,462HT
2019Estimating Trajectory of Recovery in Cardiac Rehabilitation using Mobile Health Technology and Personalized Machine Learning1R21EB028486-01MORTAZAVI, BOBAK JACKTEXAS ENGINEERING EXPERIMENT STATION, TX$208,632CICS
2019Parallel Selective Capture of Single Circulating Melanoma Cells and Integrated On-Chip Determination of Mutational Status1R21EB028583-01ANAND, ROBBYN KIMBERLYIOWA STATE UNIVERSITY, IA$208,313EBIT
2019Automated MRI-based 3D Contractility (Strain) Analysis for Detecting Subclinical Cardiotoxicity in Breast Cancer Patients Undergoing Chemotherapy1R21EB028063-01KAR, JULIAUNIVERSITY OF SOUTH ALABAMA, AL$208,194BCHI
2019Development of Methods for Precise MR-guided Hyperthermia Delivery for Targeted Cancer Therapies1R21EB026018-01A1OZHINSKY, EUGENEUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$200,313MEDI
2019Reversible block of nerve conduction using low frequency alternating currents1R21EB028469-01YOSHIDA, KENINDIANA UNIVERSITY INDIANAPOLIS, IN$196,875BNVT
2019Anti-catabolic drug anchored cationic exosomes for cartilage targeting and repair1R21EB028385-01BAJPAYEE, AMBIKA GOELNORTHEASTERN UNIVERSITY, MA$196,250SBSR
2019A novel drug loading method to protect neural cells from oxidative stress induced by a hypoxic/ischemic inflammatory environment1R21EB026723-01A1LAMPE, KYLE J.UNIVERSITY OF VIRGINIA, VA$195,825GDD
2019Liquid Crystal Elastomer as a Dynamic Treatment of Incontinence in Women1R21EB028547-01WARE, TAYLOR HUNIVERSITY OF TEXAS DALLAS, TX$193,820BMBI
2019An Ultra-Thin Molecular Imaging Skin for Intraoperative Imaging of Microscopic Residual Disease in Cancer1R21EB027238-01ANWAR, MEKHAILUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$192,456BMIT
2019Just-In-Time Fall Prevention: Development of an mHealth Intervention for Persons with Multiple Sclerosis1R21EB027852-01MCGINNIS, RYAN S.UNIVERSITY OF VERMONT & ST AGRIC COLLEGE, VT$190,538BCHI
2019Modeling heterogeneity of a cancer-signaling cascade using biomimetic cells1R21EB025938-01A1TAN, CHEEMENGUNIVERSITY OF CALIFORNIA AT DAVIS, CA$188,347MABS
2019Development and Validation of Mechanically Compliant Wearable Monitoring Systems for Swallowing Function and Disorders1R21EB026099-01A1LEE, CHI HWANMALANDRAKI, GEORGIAPURDUE UNIVERSITY, IN$187,825MFSR
2019Multiplex single-cell analysis of intracellular protein signaling dynamics1R21EB025393-01A1XUE, MINUNIVERSITY OF CALIFORNIA RIVERSIDE, CA$185,038EBIT
2019Histotripsy for collagenous tissues: a novel therapeutic approach to tendon injury1R21EB027886-01SIMON, JULIANNAVIDT, MEGHAN ELISEPENNSYLVANIA STATE UNIVERSITY, THE, PA$182,783BMIT
2019A wireless fully-passive miniaturized patient-tailored pacemaker1R21EB028396-01BLAIN CHRISTEN, JENNIFER MNIKKHAH, MEHDIARIZONA STATE UNIVERSITY-TEMPE CAMPUS, AZ$181,792CICS
2019Direct 3D Reconstruction Methods for Electrical Impedance Tomography for Stroke Imaging1R21EB028064-01HAMILTON, SARAH JMARQUETTE UNIVERSITY, WI$152,334NOIT
2019Genetic engineering RGD-containing siRNA protein carrier1R21EB026564-01A1LIU, HONG YANDOTQUANT, LLC, WA$132,000DT
2019Model Driven Construction of Dual-switch Selection Gene Drives to Combat Drug Resistance1R21EB026617-01A1PRITCHARD, JUSTINPENNSYLVANIA STATE UNIVERSITY, THE, PA$79,930MABS
2018Data-Driven Shape Analysis for Quantitative Severity Stratification in Patients with Metopic Craniosynostosis1R21EB026061-01A1GOLDSTEIN, JESSE AARONKAVAN, LADISLAVUNIVERSITY OF UTAH, UT$317,513MTE
2018An artery-on-a-chip system containing blood outgrowth endothelium as a model of vaso-occlusion and drug testing in sickle cell disease1R21EB025945-01A1JAIN, ABHISHEKTEXAS ENGINEERING EXPERIMENT STATION, TX$228,836HM
2018Engineering synthetic proteins for electron transfer based ultrafast sensing of membrane potentials1R21EB027407-01DISCHER, BOHDANAUNIVERSITY OF PENNSYLVANIA, PA$197,139BBM
2018Multimodal Probing of Neural Activity Using Transparent Microelectrode Arrays1R21EB026180-01A1KUZUM, DUYGUUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$196,250BNVT
2018A Coordination Chemistry Approach to High-Field EPR Imaging1R21EB027293-01ZADROZNY, JOSEPH MCOLORADO STATE UNIVERSITY, CO$167,806CMIP
2018Single cell magnetic microscopy with multicolor superparamagnetic probes.1R21EB027405-01ACOSTA, VICTOR MARCELUNIVERSITY OF NEW MEXICO, NM$145,698ISD

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