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NIH funding notice PAR-18-419

NIDDK Mentored Research Scientist Development Award (K01-No Independent Clinical Trials)

Closed on January 7, 2021.

Posted
November 29, 2017
Close date
January 7, 2021
Activity codes
Not stated on the notice page
Institutes taking part
Not stated on the notice page

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

Its page was not saved, so the notices it replaced are not known.

Who won it before

103 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $13,936,680 in first-year total cost, median $140,863.

Most frequent study sections

  1. Diabetes, Endocrinology and Metabolic Diseases B Study Section[DDK-B]38
  2. Digestive Diseases and Nutrition C Study Section[DDK-C]29
  3. Kidney, Urologic and Hematologic Diseases D Study Section[DDK-D]27
  4. Special Emphasis Panel[ZDK1 GRB-7 (M1)]2
  5. Special Emphasis Panel[ZDK1 GRB-G (M1)]2

Most frequent institutions

  1. BAYLOR COLLEGE OF MEDICINE5
  2. YALE UNIVERSITY5
  3. BOSTON CHILDREN'S HOSPITAL4
  4. COLUMBIA UNIVERSITY HEALTH SCIENCES4
  5. DUKE UNIVERSITY4
Competing awards under PAR-18-419 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2022The Role of Thyroglobulin in Thyroid Hormone Synthesis1K01DK125448-01A1CITTERIO, CINTIA E.UNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$117,115DDK
2021The role of local iron homeostasis in inflammatory bowel disease1K01DK128308-01BESSMAN, NICHOLAS J.RBHS-NEW JERSEY MEDICAL SCHOOL, NJ$177,809DDK
2021Long-term effectiveness of BPH/LUTS pharmacological therapies and using machine learning based predictive analytics to tailor treatment.1K01DK129405-01LANGSTON, MARVIN EPOLIANKAISER FOUNDATION RESEARCH INSTITUTE, CA$160,347DDK
2021Implementation research to improve the uptake of influenza vaccination in CKD1K01DK125616-01A1ISHIGAMI, JUNICHIJOHNS HOPKINS UNIVERSITY, MD$157,800ZDK1
2021Blocking Latent TGF-β2 Activation as a Therapeutic Strategy for Renal Fibrosis1K01DK124443-01A1LE, VIET QUOCBOSTON CHILDREN'S HOSPITAL, MA$155,346DDK
2021Mechanisms of Flow-driven Transcriptional Control of Hematopoietic Stem Cell Development by YAP1K01DK129409-01SUGDEN, WADE WILLIAMBOSTON CHILDREN'S HOSPITAL, MA$155,346ZDK1
2021Role of Small Extracellular Vesicles in Beta Cell Failure and Autoimmunity in Type 1 Diabetes Mellitus1K01DK129208-01JAVEED, NAUREENMAYO CLINIC ROCHESTER, MN$154,569DDK
2021Regulation of Hepatobiliary Bile Acid Homeostasis in Neonatal Obstructive Cholestasis1K01DK129408-01GUTHRIE, GREGORYBAYLOR COLLEGE OF MEDICINE, TX$154,423DDK
2021Characterization of the Role of Nemo-like Kinase in Normal and Diamond Blackfan Anemia Models of Erythropoiesis.1K01DK123140-01A1WILKES, MARK CHRISTOPHERSTANFORD UNIVERSITY, CA$153,888DDK
2021Iron and Pregnancy: Regulatory Mechanisms and Adverse Outcomes1K01DK127004-01SANGKHAE, VEENAUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$153,305DDK
2021Epigenetic regulation in therapeutic human pancreatic beta cell proliferation1K01DK128378-01KARAKOSE-BALIOGLU, ESRAICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY$152,916DDK
2021Multi-level Factors that Influence Dialysis Facilities' Assessments of Patient Suitability for Transplantation1K01DK128384-01WILK, ADAM STEVENEMORY UNIVERSITY, GA$152,452DDK
2021Mechanisms for the regulation of novel lipids in vivo1K01DK128075-01SANTORO, ANNABETH ISRAEL DEACONESS MEDICAL CENTER, MA$152,236DDK
2021Investigation into the role of autophagy protease ATG4A in normal and impaired erythropoiesis1K01DK128126-01STOLLA, MASSIEL CHAVEZUNIVERSITY OF WASHINGTON, WA$149,514DDK
2021The Role of MCP-1 in Tubular-to-Glomerular Crosstalk in Proteinuric Kidney Disease1K01DK124357-01A1BONDI, CORRY DOMINICUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$149,223DDK
2021Neurocircuits linking thermoregulation and feeding1K01DK126793-01DEEM, JENNIFER DEZETUNIVERSITY OF WASHINGTON, WA$149,028DDK
2021Microbiota-sourced purines in gut health and disease1K01DK129410-01LEE, JOSEPH SCOTTUNIVERSITY OF COLORADO DENVER, CO$148,921DDK
2021Defining the renal urothelium progenitor and its regulation during development and repair1K01DK126991-01A1JACKSON, ASHLEY R.RESEARCH INST NATIONWIDE CHILDREN'S HOSP, OH$146,795DDK
2021Contrasting roles for neutrophils and macrophages during acute pyelonephritis1K01DK128379-01RUIZ ROSADO, JUAN DE DIOSRESEARCH INST NATIONWIDE CHILDREN'S HOSP, OH$145,068DDK
2021Unraveling the role of osteocytes in metabolic dysfunction associated with obesity1K01DK129404-01DOLE, NEHAUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$142,399DDK
2021Role of GPR56 in glomerular endothelial cell injury in early diabetic kidney disease1K01DK125614-01A1FU, JIAICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY$140,475DDK
2021Osteopontin: A Novel Mediator of prostatic inflammation and fibrosis1K01DK127150-01POPOVICS, PETRAUNIVERSITY OF WISCONSIN-MADISON, WI$138,880ZDK1
2021The role of enteroendocrine cell differentiation in the success of bariatric surgery1K01DK129367-01KIM, KI SUKUNIVERSITY OF COLORADO DENVER, CO$135,541ZDK1
2021Therapeutic Mechanisms of Placental Stem Cell-Based Therapy in Necrotizing Enterocolitis1K01DK125633-01A1WEIS, VICTORIAWAKE FOREST UNIVERSITY HEALTH SCIENCES, NC$135,530DDK
2021Adipose-Specific Phosphatidic Acid Phosphatase Activity of Lipin 1 Regulates Systemic Insulin Sensitivity1K01DK126990-01A1LUTKEWITTE, ANDREWWASHINGTON UNIVERSITY, MO$131,079DDK
2021Glucagon and insulin act cooperatively in the regulation of prandial hepatic glycogen metabolism1K01DK129417-01CAPOZZI, MEGANDUKE UNIVERSITY, NC$129,864DDK
2021Acyl-CoA synthetase-mediated regulation of lipid homeostasis1K01DK128226-01ALVES-BEZERRA, MICHELEBAYLOR COLLEGE OF MEDICINE, TX$127,187DDK
2021Enteroendocrine Regulation of Intestinal Metabolism1K01DK125341-01A1MCCAULEY, HEATHER ACINCINNATI CHILDRENS HOSP MED CTR, OH$127,049DDK
2021Enteroendocrine cells sense gut bacteria and activate a gut-brain pathway1K01DK125527-01A1YE, LIHUADUKE UNIVERSITY, NC$126,892DDK
2021The Intestinal Mycobiome and IBD1K01DK125526-01A1DI MARTINO, LUCACASE WESTERN RESERVE UNIVERSITY, OH$123,270DDK
2021The role of Syndecan-2 in hematopoietic stem cell maintenance and regeneration1K01DK126989-01A1TERMINI, CHRISTINA MARIEUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$123,108DDK
2021Adipocyte mitochondrial distress drives the intercommunication between white and brown adipose tissues1K01DK125447-01A1AN, YUUT SOUTHWESTERN MEDICAL CENTER, TX$122,764DDK
2021Investigating the mechanisms of erythroid lineage commitment in hematopoietic stem and multipotent progenitor populations1K01DK120780-01A1KANG, YOON ACOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$121,235DDK
2021Niemann-Pick C liver-specific proteostasis and pathology1K01DK124450-01A1SCHULTZ, MARK LOUISUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$121,022DDK
2021Therapeutic mechanisms of L. lactis-mediated wound repair1K01DK127007-01A1JONES, RHEINALLT MELFYNEMORY UNIVERSITY, GA$115,347ZDK1
2021Potential activation of Disease susceptibility genes by Enhancer Release and Retargeting1K01DK126987-01A1OH, SOOHWANUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$115,073DDK
2021Novel Mechanisms Regulating Renal Perfusion and Kidney Redox Biology: Role in Salt Sensitive Hypertension1K01DK126792-01WU, JING O.MEDICAL COLLEGE OF WISCONSIN, WI$106,102DDK
2021Circadian Control of Pancreatic Beta-cell Maturation by Dec11K01DK129442-01ALVAREZ, JUAN RHARVARD UNIVERSITY, MA$102,718DDK
2020Impact of Aspirin on the Gut Microbiome and Mucosal Microenvironment1K01DK120742-01A1DREW, DAVID AMASSACHUSETTS GENERAL HOSPITAL, MA$159,720DDK
2020Deciphering the role of miR-33 in central regulation of feeding behavior1K01DK120794-01A1PRICE, NATHANYALE UNIVERSITY, CT$155,346DDK
2020Role of noncoding RNA decay in glucose homeostasis1K01DK121861-01A1PIROUZ, MEHDIBOSTON CHILDREN'S HOSPITAL, MA$155,346DDK
2020Endothelial lipid droplet turnover and regulation of metabolic function1K01DK124441-01BOUTAGY, NABILYALE UNIVERSITY, CT$154,374DDK
2020Physiologic stress and sexual orientation disparities in risk for type 2 diabetes among women1K01DK123193-01A1VANKIM, NICOLE AUNIVERSITY OF MASSACHUSETTS AMHERST, MA$154,143DDK
2020Contribution of CMV-specific T cells to chronic kidney rejection1K01DK123196-01A1HIGDON, LAURENSTANFORD UNIVERSITY, CA$154,083ZDK1
2020Lipid dysregulation of immune mediated intestinal epithelial healing1K01DK121934-01A1MCALESTER, ANDREA ALYSSABAYLOR COLLEGE OF MEDICINE, TX$153,883DDK
2020Removal of apoptotic cells during acute kidney injury1K01DK123497-01MORIOKA, SHOUNIVERSITY OF VIRGINIA, VA$153,791DDK
2020Investigating CD4 T regulatory cells during rapid cystogenesis1K01DK119375-01A1ZIMMERMAN, KURT AUNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR, OK$153,165DDK
2020Metabolic And Spatial Competition For Dietary Fiber Between Commensal And Pathogenic Gut Microbes1K01DK124445-01PATNODE, MICHAEL LWASHINGTON UNIVERSITY, MO$152,599DDK
2020The role of the Hippo Pathway in gastric homeostasis and metaplasia1K01DK120800-01A1WILLET, SPENCER GAFFNEYWASHINGTON UNIVERSITY, MO$152,453DDK
2020Dissecting Viscerosensory Pathways Controlling Feeding Behavior1K01DK124245-01CAMPOS, CARLOS AUNIVERSITY OF WASHINGTON, WA$151,069DDK
2020Novel mechanisms of redox signaling in acute kidney injury1K01DK123194-01SREELATHA, ANJUUT SOUTHWESTERN MEDICAL CENTER, TX$150,526DDK
2020Air pollution and health disparities in liver disease and cancer1K01DK125612-01VOPHAM, TRANGFRED HUTCHINSON CANCER RESEARCH CENTER, WA$150,389DDK
2020The role of vascular endothelium in BAT expansion and remodeling1K01DK125608-01SHAMSI, FARNAZJOSLIN DIABETES CENTER, MA$150,293DDK
2020Molecular mechanism of Sickle Cell Hepatic Crisis1K01DK125617-01PRADHAN-SUNDD, TIRTHADIPAUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$148,399DDK
2020The neural underpinnings of disinhibited eating behavior in adolescents with and without obesity1K01DK120562-01A1SHAPIRO, ALLISON LIVIA BUTIUNIVERSITY OF COLORADO DENVER, CO$147,338DDK
2020Biobehavioral Effects of Inhibitory Control on Eating and Diet Behaviors Among Adolescents1K01DK124435-01MASON, TYLERUNIVERSITY OF SOUTHERN CALIFORNIA, CA$147,142DDK
2020Antioxidant regulation of intestinal homeostasis and disease1K01DK123495-01SHORT, SARAH PALMERVANDERBILT UNIVERSITY MEDICAL CENTER, TN$146,793ZDK1
2020Gastrointestinal Cues Influence Metabolic Control of Regulatory T cell Function1K01DK124358-01BAMIDELE, ADEBOWALE OMAYO CLINIC ROCHESTER, MN$145,821DDK
2020Influence of genetic variation, genetic ancestry, and obesity on gestational diabetes mellitus risk1K01DK120631-01A1GIRI, AYUSHVANDERBILT UNIVERSITY MEDICAL CENTER, TN$141,758DDK
2020Glycophagy in liver and skeletal muscle insulin sensitivity and energy metabolism1K01DK125258-01HEDEN, TIMOTHY D.UNIVERSITY OF MINNESOTA, MN$140,863DDK
2020S1P as regulator of neonatal mucosal immune development and injury1K01DK125606-01RUSCONI, BRIGIDA AGNESEWASHINGTON UNIVERSITY, MO$136,922DDK
2020Defining the role of non-clock genes in circadian physiology and pathophysiology1K01DK125602-01GUAN, DONGYINUNIVERSITY OF PENNSYLVANIA, PA$132,456DDK
2020Mesenchymal regulation of fetal intestinal development and adult regeneration1K01DK125639-01MCCARTHY, NEILDANA-FARBER CANCER INST, MA$132,180DDK
2020Immune and developmental actions of the maternal microbial metabolites on the hypothalamus1K01DK121734-01A1JASAREVIC, ELDINUNIVERSITY OF MARYLAND BALTIMORE, MD$132,024DDK
2020Role of the COP9 Signalosome (CSN) in kidney disease and hypertension1K01DK120790-01A1CORNELIUS, RYAN JOREGON HEALTH & SCIENCE UNIVERSITY, OR$131,219DDK
2020Development and Validation of Computational Algorithms to Assess Kidney Health in Electronic Health Records1K01DK120784-01A1OZRAZGAT BASLANTI, TEZCANUNIVERSITY OF FLORIDA, FL$130,488DDK
2020Renal Pericytes as a Target for Angiotensin II Signaling in Hypertension1K01DK121737-01A1NELSON, JONATHAN WOREGON HEALTH & SCIENCE UNIVERSITY, OR$129,037DDK
2020Identifying the role of serotonin receptor 4 and trefoil factor 3 in intestinal wound repair1K01DK123195-01ENGEVIK, MELINDA ANNEBAYLOR COLLEGE OF MEDICINE, TX$123,648DDK
2020PRDM16 regulation of metabolism in the intestinal stem cell niche1K01DK116922-01A1STINE, RACHEL RAEBURN WEBSTERUNIVERSITY OF PENNSYLVANIA, PA$120,362DDK
2020Neuronal pathways regulating metabolic adaptation1K01DK123197-01HRVATIN, SINISAHARVARD MEDICAL SCHOOL, MA$116,293DDK
2020Advanced Glycation Endproducts, RAGE/DIAPH1 Signaling and Metabolic Dysfunction1K01DK120782-01A1RUIZ, HENRY HNEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY$110,455DDK
2020Role of Muscle Ketone Metabolism in Mediating the Metabolic Benefits of Weight Loss1K01DK125609-01WILLIAMS, ASHLEY SILBERMANDUKE UNIVERSITY, NC$103,020DDK
2020Role of the ubiquitin Ligase adaptor FBXL13 on Salt-sensitive hypertension1K01DK123192-01A1ARES-SARMIENTO, GUSTAVO RHENRY FORD HEALTH SYSTEM, MI$71,750DDK
2020Predicting Urinary Continence Status with Sacral Neuromodulation and Botulinum Toxin Treatments1K01DK121866-01A1HOKANSON, JAMES ARTHURDUKE UNIVERSITY, NC$22,825DDK
2019Fetal Programming of Growth and Obesity: A Metabolomics Approach1K01DK120807-01ZHU, YEYIKAISER FOUNDATION RESEARCH INSTITUTE, CA$163,997DDK
2019The Comparative Effectiveness and Safety of Second-line Therapy in Patients with Type 2 Diabetes1K01DK121825-01SHIN, JUNG-IMJOHNS HOPKINS UNIVERSITY, MD$158,508ZDK1
2019Melanin-concentrating hormone and the neural regulation of feeding1K01DK118000-01A1NOBLE, EMILY ELIZABETHUNIVERSITY OF SOUTHERN CALIFORNIA, CA$157,971DDK
2019IRE1beta links the gut microbiota and epithelial differentiation to protect against colitis1K01DK119414-01GREY, MICHAEL JBOSTON CHILDREN'S HOSPITAL, MA$156,276DDK
2019Direct measurement of 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1) enzyme levels in obesity using a novel positron emissiontomography radioligand1K01DK118005-01A1BINI, JASONYALE UNIVERSITY, CT$155,346DDK
2019Human milk metabolomics and microbe-host interactions associated with pediatric obesity1K01DK115632-01A1LEMAS, DOMINICK JOSEPHUNIVERSITY OF FLORIDA, FL$152,333DDK
2019Advanced sequencing as a novel diagnostic tool to discover strain-level variation and function of mucosal-adherent bacteria contributing to IBD1K01DK119582-01A1WANG, JEREMY RUNIV OF NORTH CAROLINA CHAPEL HILL, NC$152,091DDK
2019Regulation of neural function by astrocyte insulin and IGF-1 receptor signaling1K01DK120740-01CAI, WEIKANGJOSLIN DIABETES CENTER, MA$148,394DDK
2019Evidence of the burden of diabetes, gaps in the diabetes cascade-of-care and the impact of care and treatment on diabetes outcomes in HIV-positive and HIV-negative patients in South Africa1K01DK116929-01A1BRENNAN, ALANA TERESABOSTON UNIVERSITY MEDICAL CAMPUS, MA$148,200DDK
2019Glucocorticoid and circadian clock coregulation of insulin sensitivity and metabolism1K01DK121875-01QUATTROCELLI, MATTIANORTHWESTERN UNIVERSITY AT CHICAGO, IL$144,352DDK
2019Neuropathic vs. inflammatory pain in chronic pancreatitis: can unique biomarkers be identified to guide mechanistic approaches to pain treatment?1K01DK120737-01SALOMAN, JAMI LYNNUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$138,350DDK
2019The role of Myosin Vb in hepatocyte protein trafficking1K01DK121869-01ENGEVIK, AMY CVANDERBILT UNIVERSITY MEDICAL CENTER, TN$134,963DDK
2019TOX4 integrates hormone signaling on hepatic glucose and lipid metabolism1K01DK123199-01WANG, LIHENGCOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$132,450DDK
2019Rare variant analysis of glomerulonephritis1K01DK119549-01NA, YOUNGJICOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$132,342ZDK1
2019Gut cell plasticity during diabetes treatment1K01DK121873-01MCKIMPSON, WENDY MARIECOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$132,290DDK
2019Secreted Micropeptides in the Regulation of Metabolic Homeostasis1K01DK116926-01A1BOOKOUT, ANGIE LYNNUT SOUTHWESTERN MEDICAL CENTER, TX$123,972DDK
2019Interactions of Intestinal Epithelial Cells, The Innate Immune System and Gut Microbiota During Dysbiosis1K01DK121864-01NEFF, CHARLES PRESTONUNIVERSITY OF COLORADO DENVER, CO$123,084DDK
2019Targeting macrophage persistence to prevent the AKI-to-CKD transition1K01DK120783-01XU, LEYUANYALE UNIVERSITY, CT$122,173DDK
2019Enhancer Codes with Ligand Mediated Gene Regulation and Chromatin Architecture1K01DK121871-01NAIR, SREEJITH JANARDHANANUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$119,706DDK
2019A TAP63 TRANSCRIPTIONAL AXIS CONTRIBUTES TO THE SEXUAL DIMORPHISM IN POMC NEURON FUNCTIONS AND ENERGY HOMEOSTASIS1K01DK119471-01A1WANG, CHUNMEIBAYLOR COLLEGE OF MEDICINE, TX$118,242DDK
2019The Role of Intrinsic and Extrinsic Factors in Megakaryocytic-Erythroid Progenitor Lineage Commitment1K01DK120798-01SCANLON, VANESSA M.YALE UNIVERSITY, CT$116,567DDK
2019HuR as a Regulator of Skeletal Muscle Metabolism1K01DK116914-01A1WARFEL, JAYCOB DALTONLSU PENNINGTON BIOMEDICAL RESEARCH CTR, LA$114,036DDK
2019Deregulation of Long Noncoding RNA in the Pathogenesis of Autosomal Dominant Polycystic Kidney Disease1K01DK116934-01A1ABOUDEHEN, KARAMUNIVERSITY OF MINNESOTA, MN$110,027DDK
2019The Role of DDX41 in Inherited Myelodysplastic Syndromes1K01DK121733-01CHLON, TIMOTHY MICHAELCINCINNATI CHILDRENS HOSP MED CTR, OH$109,495DDK
2019Early and Transient Activation of Fibroblasts Promotes Tubule Repair after Acute Kidney Injury1K01DK116816-01A1ZHOU, DONGUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$91,309DDK
2019A role of chromatin remodeling complexes in beta cell dysfunction1K01DK120808-01A1WEI, ZONGSALK INSTITUTE FOR BIOLOGICAL STUDIES, CA$25,674DDK
2018Impact of mitochondrial dynamics on the development of renal cysts in Tuberous Sclerosis Complex (TSC)1K01DK116819-01A1LAM, HILAIRE COLLETTABRIGHAM AND WOMEN'S HOSPITAL, MA$157,459DDK
2018See-ing the 4D Nucleome: Enhancer Cooperativity in Phase Separated Structures1K01DK119687-01MELUZZI, DARIOUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$119,706DDK
2018Myeloid lineage activation and reprogramming in metabolic dysfunction1K01DK116928-01A1MUIR, LINDSEY ALLISONUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$93,758DDK

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PAR-18-419: NIDDK Mentored Research Scientist Development Award (K01-No Independent Clinical Trials) | ScienceDex | ConductScience