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NIH funding notice PAR-18-433

NIBIB Exploratory/Developmental Research Grant Program (R21) (Clinical Trial Optional)

Closed on May 7, 2021.

Posted
December 15, 2017
Close date
May 7, 2021
Activity codes
Not stated on the notice page
Institutes taking part
Not stated on the notice page

Read the notice on Grants.gov ยท NIH Guide page

The notices it replaced

Its page was not saved, so the notices it replaced are not known.

Who won it before

97 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $24,933,068 in first-year total cost, median $226,779.

Most frequent study sections

  1. Imaging Technology Development Study Section[ITD]17
  2. Imaging Probes and Contrast Agents Study Section[IPCA]9
  3. Nanotechnology Study Section[NANO]9
  4. Emerging Imaging Technologies and Applications Study Section[EITA]7
  5. Biomaterials and Biointerfaces Study Section[BMBI]6

Most frequent institutions

  1. MASSACHUSETTS GENERAL HOSPITAL4
  2. NEW YORK UNIVERSITY SCHOOL OF MEDICINE4
  3. UNIVERSITY OF PENNSYLVANIA4
  4. JOHNS HOPKINS UNIVERSITY3
  5. UNIVERSITY OF CALIFORNIA LOS ANGELES3
Competing awards under PAR-18-433 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2022MRI-Based Regional Assessment of Cerebral Metabolism Via 3D Quantitative BOLD1R21EB031364-01A1WEHRLI, FELIX WUNIVERSITY OF PENNSYLVANIA, PA$243,750EITN
2022Multiplexed electronic counting of scarce protein targets using nucleic acid nanoparticles1R21EB032640-01AFONIN, KIRILL AAKSIMENTIEV, ALEKSEIWANUNU, MENIUNIVERSITY OF NORTH CAROLINA CHARLOTTE, NC$243,311NANO
2022RetroDecoys: Temporally-regulated and cell type selective technology for transcriptional control1R21EB031393-01A1SHIPMAN, SETH LAWLERJ. DAVID GLADSTONE INSTITUTES, CA$236,250CMT
2022Dynamic Nuclear Polarization of Aerosols - A Novel Approach for Imaging Water Vapor and Enabling Lung Imaging1R21EB031336-01A1ALON, LEEORJERSCHOW, ALEXEJNEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY$226,626ITD
2022Novel optogenetic tool for noninvasive neuronal inhibition1R21EB032609-01GOMELSKY, MARKSUN, QIAN-QUANUNIVERSITY OF WYOMING, WY$180,625MNG
2021Causal connectivity along the spinal cord using high-resolution 7T fMRI1R21EB031211-01BARRY, ROBERT LMASSACHUSETTS GENERAL HOSPITAL, MA$462,000CTIS
2021Multiplexed device for rapid coagulopathy testing1R21EB031982-01HARDIN, CHARLES COREYMUNN, LANCE L.MASSACHUSETTS GENERAL HOSPITAL, MA$462,000ZRG1
2021iPPSIS: implanted Passive Pressure Sensor Interrogated with (ultra)-Sound1R21EB031545-01LINDSEY, BROOKS DMYERS, DAVID RICHARDEMORY UNIVERSITY, GA$450,081BNVT
2021Dual Energy CT-enabled Asymptomatic Pulmonary Embolism Detection on Non-contrast CT1R21EB031939-01WU, DUFANMASSACHUSETTS GENERAL HOSPITAL, MA$448,656EITA
2021Method for assessing women's perceptions of their appearance in the context of breast cancer care1R21EB031317-01MARKEY, MIA KUNIVERSITY OF TEXAS AT AUSTIN, TX$432,988NRCS
2021Paper-COVID - Platform for High-throughput SARS-CoV-2 Screening and Contact Tracing1R21EB031466-01ERICKSON, DAVID CARLCORNELL UNIVERSITY, NY$432,028ZRG1
2021Multi-target suppression of pro-inflammatory cytokines using engineered targeted ribonucleases1R21EB032019-01MICHEL, SARAH LWILSON, GERALD M.UNIVERSITY OF MARYLAND BALTIMORE, MD$424,875GDD
2021A Rapid and Sensitive Technology for Direct Sensing of Intact SARS-CoV-2 Virions Using Designer DNA Nanostructure Probes and a Smartphone Fluorimeter1R21EB031310-01CUNNINGHAM, BRIAN T.WANG, XINGUNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN, IL$422,226NANO
2021Towards a Convenient, Point-of-Care Device for Screening and Surveillance of Aortic Aneurysms1R21EB029376-01A1MUKKAMALA, RAMAKRISHNAUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$410,344BCHI
2021Design and evaluation of a multivalent nanobody construct for prevention or treatment of SARS-CoV-21R21EB031597-01CHAMPION, JULIEGEORGIA INSTITUTE OF TECHNOLOGY, GA$397,382NANO
2021Development of a platform to non-invasively assess microvascular endothelial dysfunction at the bedside in COVID-19 patients throughout intensive care.1R21EB031261-01BUSCH, DAVID RICHARDUT SOUTHWESTERN MEDICAL CENTER, TX$385,726IGIS
2021A Feasibility Study of a High-Throughput Live-Cell Microscopy Design for Visualizing Viral Particle Action and Nano-Carrier Delivery Performance1R21EB031374-01YANG, HAWPRINCETON UNIVERSITY, NJ$363,354CMT
2021Development and Deployment of an Electrochemical Antigen Testing System for SARS-CoV-21R21EB031235-01KELLEY, SHANA OUNIVERSITY OF TORONTO, ON$295,888ZRG1
2021Zwitterionic Dendrimer-modified PEG for Protein Conjugation1R21EB032240-01CHENG, CHONGWU, YUNSTATE UNIVERSITY OF NEW YORK AT BUFFALO, NY$236,912ZRG1
2021Near Infrared Light Activated Adhesives for Nerve Repair1R21EB030798-01REGE, KAUSHALARIZONA STATE UNIVERSITY-TEMPE CAMPUS, AZ$236,458BMBI
2021Multifunctional Nanoprobe for Early Appraisal of Immunotherapeutic Efficacy1R21EB030171-01A1MORRISSEY, JEREMIAH JSINGAMANENI, SRIKANTHWASHINGTON UNIVERSITY, MO$236,250CBSS
2021A Complete Metal Artifact Reduced MRI Exam for Neuroimaging1R21EB030123-01A1KOCH, KEVIN MNENCKA, ANDREW SMEDICAL COLLEGE OF WISCONSIN, WI$234,000ZRG1
2021Flexible Piezoelectric Array for Cardiovascular MonitoringDuring Cardiac Arrest1R21EB032056-01ZHANG, XIAOJINGDARTMOUTH COLLEGE, NH$232,061ZRG1
2021Gas microbubbles as a hyperpolarized-xenon carrier and as a contrast agent for MRI1R21EB031319-01BRANCA, ROSA TAMARAUNIV OF NORTH CAROLINA CHAPEL HILL, NC$225,891IPCA
2021CRISPRa induced expression of native MRI reporter proteins1R21EB032110-01SHAPIRO, ERIKMICHIGAN STATE UNIVERSITY, MI$222,962EITA
2021Development of radiological clips having ultrasound identification1R21EB030743-01A1OELZE, MICHAEL L.UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN, IL$222,139ITD
2021Positronium lifetime imaging using TOF PET1R21EB032101-01QI, JINYIUNIVERSITY OF CALIFORNIA AT DAVIS, CA$221,250ITD
2021Non-resonance Electron Spin Imaging1R21EB030228-01A1TSEYTLIN, MARKWEST VIRGINIA UNIVERSITY, WV$218,954ITD
2021Frequency domain diffuse optical spectroscopy and diffuse correlation spectroscopy for assessing inspiratory muscle metabolism in mechanically ventilated patients1R21EB031250-01ROBLYER, DARREN MICHAELBOSTON UNIVERSITY (CHARLES RIVER CAMPUS), MA$215,000ITD
2021A novel design platform for diaCEST agents1R21EB031367-01KOVACS, ZOLTANUT SOUTHWESTERN MEDICAL CENTER, TX$204,844IPCA
2021Renally clearable ytterbium nanoparticle contrast agents for spectral photon counting computed tomography1R21EB030373-01A1CORMODE, DAVID PETERUNIVERSITY OF PENNSYLVANIA, PA$203,125ZRG1
2021Tumor casting hydrogels for interventional radiology treatment of hepatocellular carcinoma1R21EB029556-01A1CORMODE, DAVID PETERUNIVERSITY OF PENNSYLVANIA, PA$203,020IGIS
2021Development of fluorinated dyes for deeper tissue photoacoustic imaging with phase changing nanodroplets1R21EB030805-01A1BOUCHARD, RICHARD R.SOKOLOV, KONSTANTIN VUNIVERSITY OF TX MD ANDERSON CAN CTR, TX$202,500IPCA
2021Diagnosis of low-grade glial tumors using 11C glutamine isotopomers1R21EB030899-01A1VILLANUEVA-MEYER, JAVIERWILSON, DAVID MUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$201,875ZRG1
2021Synthetic mucus for local therapeutic delivery1R21EB030834-01DUNCAN, GREGGMAISEL, KATHARINAUNIV OF MARYLAND, COLLEGE PARK, MD$193,125BMBI
2021Next-Generation Cardiovascular MRI powered by Artificial Intelligence1R21EB030806-01A1COSSAIRT, OLIVER STRIDESKATSAGGELOS, AGGELOS KKIM, DANIELNORTHWESTERN UNIVERSITY AT CHICAGO, IL$189,806ITD
2021Electrical spectral imaging using magnetic resonance methods1R21EB030858-01A1SADLEIR, ROSALIND JARIZONA STATE UNIVERSITY-TEMPE CAMPUS, AZ$187,186ITD
2021Biodegradable microfuses to enable the safe and compliant long-term interval dosing of 5HT2A agonists1R21EB031454-01A1WALKER, GLENN MADISONWERFEL, THOMAS AUNIVERSITY OF MISSISSIPPI, MS$182,500GDD
2021Develop Multiphoton Magnetic Resonance Imaging1R21EB030157-01A1LIU, CHUNLEIUNIVERSITY OF CALIFORNIA BERKELEY, CA$179,154ITD
2021Nanoparticle-based optical magnetometer for room-temperature magnetoencephalography1R21EB029541-01A1HUANG, SHU-WEIUNIVERSITY OF COLORADO, CO$175,408EITN
2020Transcranial Photoacoustic Imaging Using a Virtual Array1R21EB027981-01A1JING, YUNPENNSYLVANIA STATE UNIVERSITY, THE, PA$455,226ITD
2020Gastric Electrical Slow Wave Functional MRI of the Human Brain1R21EB030009-01PEKAR, JAMES J.HUGO W. MOSER RES INST KENNEDY KRIEGER, MD$445,924CTIS
2020Quantitative Cardiac Sodium MRI1R21EB029168-01AXEL, LEONMADELIN, GUILLAUMENEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY$432,528EITA
2020Mapping the sociotechnical ecosystem of precision medicine1R21EB026290-01A1PLATT, JODYN ELIZABETHUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$425,385BCHI
2020Enzyme-enabled hyperpolarized 13C MRI for antibody-targeted imaging1R21EB029083-01A1KAO, JOSEPH PAO YUNGMAYER, DIRKUNIVERSITY OF MARYLAND BALTIMORE, MD$424,875IPCA
2020Paper-Analytical Device for Saliva Biomarker Diagnostics1R21EB030349-01HENRY, CHARLES SCOLORADO STATE UNIVERSITY, CO$371,319ISD
2020Intra-operative 4-D soft tissue perfusion using no gantry rotation (IPEN)1R21EB029049-01TAGUCHI, KATSUYUKIJOHNS HOPKINS UNIVERSITY, MD$276,363ITD
2020Novel in-vivo ultrasound-based point-of-care instrument to assess myopia level and progression1R21EB028084-01A1MAMOU, JONATHANRIVERSIDE RESEARCH INSTITUTE, NY$273,595EITA
2020FAIR-CT: a practical approach to enable ultra-low dose CT for longitudinal disease and treatment monitoring1R21EB029179-01NOO, FREDERICYIN, ZHYEUNIVERSITY OF UTAH, UT$265,345EITA
2020Exploration of Ultrasound-Activated Bubbles as a Switchable MRI Contrast Agent1R21EB030208-01SEIBERLICH, NICOLEUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$250,439EITA
2020A scalable non-intrusive image annotation method using eye tracking for training deep learning models in radiology1R21EB028367-01A1TASDIZEN, TOLGAUNIVERSITY OF UTAH, UT$243,364EITA
2020Exploiting Melanin Synthesis to Improve Tumor Detection with Multispectral Optoacoustic Tomography and Optical Guided Surgery1R21EB028062-01A1PAGEL, MARK DAVIDUNIVERSITY OF TX MD ANDERSON CAN CTR, TX$243,000IPCA
2020Quasi-ideal photon counting x-ray CT with multi-energy inter-pixel coincidence counter (MEICC)1R21EB029739-01TAGUCHI, KATSUYUKIJOHNS HOPKINS UNIVERSITY, MD$238,568ITD
2020"FLEXIBLE LIGHT FIELD 3D ENDOSCOPY1R21EB028375-01A1GAO, LIANGUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$234,000ITD
2020Novel 3D printed microneedle patches for detection of viral infections1R21EB029682-01LAKSHMANANE, PREMKUMARTIAN, SHAOMINUNIV OF NORTH CAROLINA CHAPEL HILL, NC$233,250BMBI
2020HyPET: A Hybrid TOF, DOI PET Detector for a Prostate Specific Imaging System1R21EB028420-01A1MIYAOKA, ROBERT SUNIVERSITY OF WASHINGTON, WA$224,073ITD
2020Structured chromatic light sheet microscopy1R21EB029599-01LIANG, RONGGUANGUNIVERSITY OF ARIZONA, AZ$220,670ISD
2020Hybrid-nanomaterials for non-genetic optical stimulation of excitable cells1R21EB029164-01A1COHEN-KARNI, TZAHICARNEGIE-MELLON UNIVERSITY, PA$218,312NANO
2020Bioresorbable RF Coils For Post-Surgical Monitoring by MRI1R21EB027881-01A1DOES, MARK DVANDERBILT UNIVERSITY, TN$215,290ITD
2020Enabling Continuous in vivo Metabolic Monitoring with Microencapsulated SERS Assays1R21EB028973-01MCSHANE, MIKETEXAS ENGINEERING EXPERIMENT STATION, TX$213,445NANO
2020Quadri-nuclear MRI to Study Brain Energy Metabolism1R21EB027263-01A1BROWN, RYANMADELIN, GUILLAUMENEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY$211,875ITD
2020The Role of C-Flip in Mediating Pro-Survival Macrophages in the Foreign Body Response1R21EB029261-01A1BRYANT, STEPHANIE JJANSSEN, WILLIAMUNIVERSITY OF COLORADO, CO$211,132BMBI
2020Small Molecule GPCR Ligands for Oncologic Imaging1R21EB028302-01A1ROGERS, BUCK E.XU, JINBINWASHINGTON UNIVERSITY, MO$196,771IPCA
2020Engineered Antibodies as PET Probes for Monitoring Immunotherapy Responses1R21EB029650-01EDWARDS, WILSON BARRYKOHANBASH, GARYUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$195,625IPCA
2020A PET Radiotracer for Diagnostic and Theranostics Imaging in Lyme Disease1R21EB030275-01QIU, WEIGANGZEGLIS, BRIAN MATTHEWHUNTER COLLEGE, NY$195,000IPCA
2020Single-molecule counting of circular RNAs using phage nanoparticles as surrogates1R21EB028958-01CAO, BINRUIUNIVERSITY OF OKLAHOMA, OK$189,469NANO
2020Flexible bioelectronic sensors for non-contact detection of obstruction in pediatric vascular shunts1R21EB028399-01A1MENG, ELLISUNIVERSITY OF SOUTHERN CALIFORNIA, CA$178,082BTSS
2019Focal ultrasound-mediated nonthermal ablation of brain tumors1R21EB027506-01PORTER, TYRONEBOSTON UNIVERSITY (CHARLES RIVER CAMPUS), MA$269,662ZRG1
2019Development of BBB Permeable PD-L1 PET Imaging Agents1R21EB027872-01A1CAI, ZHENGXINYALE UNIVERSITY, CT$251,250IPCA
2019Auxetic Ventricular Support Device for Chronic Myocardial Infarction1R21EB028520-01COSTA, KEVIN DXU, JUNQIAN GORDONICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY$247,442BTSS
2019Acousto-optic modulated interferometric DCS (iDCS) operating at 1064 nm1R21EB028626-01FRANCESCHINI, MARIA ANGELAMASSACHUSETTS GENERAL HOSPITAL, MA$247,400ZRG1
2019Measuring Tumor Acidosis with PET/MRI Contrast Agents1R21EB027197-01A1PAGEL, MARK DAVIDUNIVERSITY OF TX MD ANDERSON CAN CTR, TX$240,000CMIP
2019Computer Vision-Based Navigation System for High-Precision Orthopedic Trauma Surgery1R21EB028330-01SIEWERDSEN, JEFFREY HJOHNS HOPKINS UNIVERSITY, MD$238,182IGIS
2019Building and Validating a Novel Fluidic Model of the Small Intestine1R21EB028041-01MARCH, JOHN CCORNELL UNIVERSITY, NY$235,500GMPB
2019Novel microscale purification methods for complete microfluidic production of high molar activity PET radiotracers1R21EB024243-01A1VAN DAM, ROBERT MICHAELUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$234,000CMIP
2019Developing Database and Software infrastructure for Quantitative Radiologic Analysis of Lumbar Radiculopathy1R21EB026665-01A1MACYSZYN, LUKEUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$234,000BDMA
2019Enhanced megavoltage imaging for radiotherapy by light-field imaging of scintillators1R21EB028103-01LA RIVIERE, PATRICK JEANWIERSMA, RODNEYUNIVERSITY OF CHICAGO, IL$231,236BMIT
2019Photoacoustic-imaging-guided intravascular sonothrombolysis1R21EB027304-01A1JIANG, XIAONINGYAO, JUNJIENORTH CAROLINA STATE UNIVERSITY RALEIGH, NC$228,655BMIT
2019Artery-on-a-chip with perivascular adipose tissue for pressure myography1R21EB028466-01MORSS CLYNE, ALISA SUNIV OF MARYLAND, COLLEGE PARK, MD$226,779CMT
2019Ultrasound-Activated Piezoelectric P(VDF-TrFE) Nanoparticles for Electric Ablation of Cancer Cells1R21EB027857-01A1CAI, WEIBOWANG, XUDONGUNIVERSITY OF WISCONSIN-MADISON, WI$225,900NANO
2019Reliable Miniature Implantable Connectors with High Channel Density for Advanced Neural-Interface Applications1R21EB028079-01JUDY, JACK WUNIVERSITY OF FLORIDA, FL$222,814BNVT
2019Real-time non-intrusive workload monitoring-Integration of human factors in surgery training and assessment1R21EB026177-01A1YU, DENNYPURDUE UNIVERSITY, IN$221,595BCHI
2019Microstructured Intestinal Retentive Devices for Sustained Oral Delivery1R21EB026073-01A1BETTINGER, CHRISTOPHER JOHNCARNEGIE-MELLON UNIVERSITY, PA$212,087BMBI
2019Low-complexity decoupling of multi-frequency arrays for magnetic resonance imaging and spectroscopy using operational amplifiers1R21EB028516-01WRIGHT, STEVEN MTEXAS ENGINEERING EXPERIMENT STATION, TX$211,682ITD
2019Development of Multi-Compartment MR-Fingerprinting for Subvoxel Estimation of Quantitative Tissue Biomarkers1R21EB027241-01A1ASSLAENDER, JAKOBKNOLL, FLORIANNEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY$209,851ITD
2019Suppressing Radiotherapy-Induced Metastasis in Aggressive Breast Cancers via 'On-Demand' siRNA Delivery from Responsive Polymer Nanoparticles1R21EB028108-01SULLIVAN, MILLICENT OUNIVERSITY OF DELAWARE, DE$197,067NANO
2019Zwitterionic Polypeptide-protein Conjugation for the Safe and Efficient Delivery of Therapeutic Enzymes1R21EB027843-01JIANG, SHAOYIUNIVERSITY OF WASHINGTON, WA$194,375GDD
2019Employing Novel Porcine Models of Orthotopic Pancreatic Cancer to Evaluate Histotripsy Based Tumor Ablation Strategies1R21EB028429-01ALLEN, IRVING CVIRGINIA POLYTECHNIC INST AND ST UNIV, VA$194,262IGIS
2019Targeted nanoprobes for multiplexed 19F-MRI of macrophage polarization markers1R21EB026667-01A1LOUIE, ANGELIQUE YUNIVERSITY OF CALIFORNIA AT DAVIS, CA$188,874CMIP
2019Nonlinear Photoacoustic Response from Functionalized Gold and Metal Oxide Nanostructures1R21EB027319-01CHA, JENNIFER NGOODWIN, ANDREW PMURRAY, TODDUNIVERSITY OF COLORADO, CO$184,417NANO
2019Epigenetic regulation of macrophage response to biomaterial implants1R21EB027840-01DOWNING, TIMOTHY LAMONTLIU, WENDYUNIVERSITY OF CALIFORNIA-IRVINE, CA$180,075BMBI
2019Mirror image DNA circuitry for complex microRNA analysis in live cells1R21EB027855-01SCZEPANSKI, JONATHAN THOMASTEXAS A&M UNIVERSITY, TX$177,861CMT
2019A Kilohertz-Frequency, Continuous-Wave Transcranial Magnetic Stimulator to Increase the Dynamic Range of Subthreshold Neuromodulation1R21EB028075-01A1IVRY, RICHARDUNIVERSITY OF CALIFORNIA BERKELEY, CA$123,752ZRG1
2018Demonstrate Efficacy of Low-Intensity-Ultrasound in Improving Microfracture Outcomes.1R21EB025921-01A1SUBRAMANIAN, ANURADHAUNIVERSITY OF ALABAMA IN HUNTSVILLE, AL$231,910MTE
2018A molecular probe for high-resolution dual imaging of temperature and oxygen in vivo1R21EB027397-01VINOGRADOV, SERGEIUNIVERSITY OF PENNSYLVANIA, PA$219,111CMT
2018Real-time ultrasonic visualization and feedback for focused ultrasound therapy1R21EB023403-01A1OELZE, MICHAEL L.UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN, IL$216,449BMIT
2018Adding MRE to DTI for free1R21EB026238-01A1KLATT, DIETERUNIVERSITY OF ILLINOIS AT CHICAGO, IL$211,425BMIT

Data: Grants.gov's daily extract and NIH's notice pages and award files, in ScienceGraph release conductgrants-2026-11-09-0.1.0. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.

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