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NIH funding notice PAR-18-434

Synthetic Biology for Engineering Applications (R01) (Clinical Trial Optional)

Closed on January 7, 2021.

Posted
December 15, 2017
Close date
January 7, 2021
Activity codes
Not stated on the notice page
Institutes taking part
Not stated on the notice page

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

Its page was not saved, so the notices it replaced are not known.

Who won it before

21 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $11,553,153 in first-year total cost, median $428,141.

Most frequent study sections

  1. Cellular and Molecular Technologies Study Section[CMT]11
  2. Genomics, Computational Biology and Technology Study Section[GCAT]2
  3. Modeling and Analysis of Biological Systems Study Section[MABS]2
  4. Cellular and Molecular Immunology - A Study Section[CMIA]1
  5. Developmental Therapeutics Study Section[DT]1

Most frequent institutions

  1. BOSTON UNIVERSITY (CHARLES RIVER CAMPUS)4
  2. MASSACHUSETTS INSTITUTE OF TECHNOLOGY2
  3. RICE UNIVERSITY2
  4. UNIVERSITY OF TEXAS AT AUSTIN2
  5. CALIFORNIA INSTITUTE OF TECHNOLOGY1
Competing awards under PAR-18-434 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2021Semi-synthetic, magneto-photonic circuit for non-invasive control of cellular function1R01EB031936-01GILAD, ASSAF AHOCHGESCHWENDER, UTE HCENTRAL MICHIGAN UNIVERSITY, MI$2,026,634CMT
2021A high-performance and versatile technology for precision microbiome engineering1R01EB031935-01STERNBERG, SAMUEL HENRYWANG, HARRIS HCOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$688,498GCAT
2021Synthetic gene sensors and effectors to redirect organoid development1R01EB030946-01BELTA, CALINKEMP, MELISSA LAMBETHWEISS, RONMASSACHUSETTS INSTITUTE OF TECHNOLOGY, MA$682,610ZRG1
2021Evolution and optimization of synthetic <READ/WRITE> function from and into cells using genetic programming1R01EB030565-01BANZHAF, WOLFGANGGILAD, ASSAF AMICHIGAN STATE UNIVERSITY, MI$579,888CMT
2021Directed evolution of a sequence-specific targeting technology for therapeutic gene delivery to the human genome.1R01EB031124-01OWENS, JESSE BRUCEUNIVERSITY OF HAWAII AT MANOA, HI$574,713GDD
2021Programmable gene integration and cell engineering with CRISPR-directed integrases1R01EB031957-01ABUDAYYEH, OMAR OGOOTENBERG, JONATHAN SAMUELMASSACHUSETTS INSTITUTE OF TECHNOLOGY, MA$568,123TAG
2021Targeted control of self-transmissible plasmids by using engineered interfering plasmids1R01EB031869-01YOU, LINGCHONGDUKE UNIVERSITY, NC$428,141MABS
2021Synthetic epigenetic circuits: tunable cell fate switches controlled by dynamic and combinatorial inputs1R01CA253017-01A1BARBOSA DE ALMEIDA, RICARDO AUGUSTOLIM, WENDELL AUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$413,916CMT
2021Multiplexed and Logical Control of the Mammalian Transcriptome Using Cas131R01EB031904-01WONG, WILSONBOSTON UNIVERSITY (CHARLES RIVER CAMPUS), MA$396,889CMT
2021A synthetic signaling pathway engineering platform for creating precision cell-based sense-and-response devices1R01EB032272-01BASHOR, CALEBRICE UNIVERSITY, TX$344,920CMT
2021Engineering mammalian gene activity sensor-actuator devices1R01EB030030-01A1SEGATORI, LAURARICE UNIVERSITY, TX$339,400CMT
2020Synthetic toolkit for precision gene expression control and signal processing in mammalian cells1R01EB029483-01KHALIL, AHMAD SAMIRBOSTON UNIVERSITY (CHARLES RIVER CAMPUS), MA$704,349CMT
2020Cell targeting with synthetic sense-and-respond protease circuits1R01EB030015-01ELOWITZ, MICHAEL BCALIFORNIA INSTITUTE OF TECHNOLOGY, CA$602,432CMT
2020Engineering S. typhimurium for metastatic colorectal cancer1R01EB029750-01A1DANINO, TALCOLUMBIA UNIV NEW YORK MORNINGSIDE, NY$346,661DT
2020Directed evolution of polymerases that can read and write extremely long sequences1R01EB027202-01A1ELLINGTON, ANDREW DUNIVERSITY OF TEXAS AT AUSTIN, TX$329,742GCAT
2020Development of a mechanosensitive synthetic cell for mediating intercellular communication.1R01EB030031-01LIU, ALLEN PO-CHIHUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$270,490CMT
2019ePACE: an automated system for high-throughput, closed-loop control of continuous molecular evolution to enable novel therapeutics1R01EB027793-01KHALIL, AHMAD SAMIRBOSTON UNIVERSITY (CHARLES RIVER CAMPUS), MA$687,081ISD
2019Programmable Synthetic Organelles Built from Disordered Proteins for Cellular Engineering1R01EB028320-01GOOD, MATTHEW CHARLTONHAMMER, DANIEL AUNIVERSITY OF PENNSYLVANIA, PA$429,904CMT
2019Integration of systems and synthetic biology to advance development of human tissues ex vivo1R01EB028532-01EBRAHIMKHANI, MO REZAUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$426,312CMT
2019Engineering a smart CAR platform for human regulatory T cells1R56EB027729-01A1DOOMS, HANS PETEREMILI, ANDREWWONG, WILSONBOSTON UNIVERSITY (CHARLES RIVER CAMPUS), MA$357,217CMIA
2019Synthetic biology for controlled release1R01EB026533-01A1ELLINGTON, ANDREW DUNIVERSITY OF TEXAS AT AUSTIN, TX$355,233MABS

Data: Grants.gov's daily extract and NIH's notice pages and award files, in ScienceGraph release conductgrants-2026-11-09-0.1.0. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.

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