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NIH funding notice PAR-18-467

The NCI Transition Career Development Award (K22 - Independent Clinical Trial Not Allowed)

Closed on March 12, 2021.

Posted
December 6, 2017
Close date
March 12, 2021
Activity codes
Not stated on the notice page
Institutes taking part
Not stated on the notice page

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

Its page was not saved, so the notices it replaced are not known.

Who won it before

62 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $11,236,533 in first-year total cost, median $188,143.

Most frequent study sections

  1. Transition to Independence Study Section (I)[NCI-I (B)]18
  2. Transition to Independence Study Section (I)[NCI-I]15
  3. Special Emphasis Panel[ZCA1 RTRB-R (J1)]11
  4. Special Emphasis Panel[ZCA1 RTRB-R (O2)]11
  5. Special Emphasis Panel[ZCA1 RTRB-R (M2)]7

Most frequent institutions

  1. COLUMBIA UNIVERSITY HEALTH SCIENCES3
  2. DUKE UNIVERSITY3
  3. ALBERT EINSTEIN COLLEGE OF MEDICINE2
  4. FRED HUTCHINSON CANCER RESEARCH CENTER2
  5. JOHNS HOPKINS UNIVERSITY2
Competing awards under PAR-18-467 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2023Targeting Oncogenic PELP1/SRC-3 Signaling Complexes in ER+ Breast Cancer1K22CA248615-01A1TRUONG, THU HAUNIVERSITY OF MINNESOTA, MN$201,744ZCA1
2023Decoding the functional pleiotropy of IL-20Rβ ligands in inflammation and tumorigenesis1K22CA266531-01SAXTON, ROBERT ANDREWUNIVERSITY OF CALIFORNIA BERKELEY, CA$200,232ZCA1
2023Understanding initiation and progression of IPMNs in pancreatic cancer1K22CA266747-01DESAI, RIDHDHI RDREXEL UNIVERSITY, PA$194,400ZCA1
2023The HDAC3 pathway in LKB1-mutant lung cancer and senescence1K22CA251636-01A1EICHNER, LILLIAN J.NORTHWESTERN UNIVERSITY AT CHICAGO, IL$191,052ZCA1
2023Targeting Adaptive Radioresistance of Glioblastoma1K22CA263305-01A1OSUKA, SATORUUNIVERSITY OF ALABAMA AT BIRMINGHAM, AL$108,000ZCA1
2022Potentiating the Efficacy of Immune Checkpoint Blockade by Targeting Epithelial-Mesenchymal Transition (EMT)-induced Immunosuppression in Breast Carcinomas1K22CA255420-01DONGRE, ANUSHKACORNELL UNIVERSITY, NY$227,902ZCA1
2022Tumor-TAMs crosstalk enables bypass of oncogenic KRAS dependency in pancreatic cancer1K22CA251491-01HOU, PINGPINGRBHS-NEW JERSEY MEDICAL SCHOOL, NJ$200,281NCI
2022Leveraging high-risk populations for precision prevention: A novel approach for improving risk prediction for outcomes after a breast cancer diagnosis1K22CA251493-01A1ZEINOMAR, NURRUTGERS BIOMEDICAL AND HEALTH SCIENCES, NJ$199,896ZCA1
2022Opioid-induced changes to chemotherapeutic activity in blood cancer1K22CA258671-01A1CONSTANCE, JONATHAN ERICUNIVERSITY OF UTAH, UT$198,348ZCA1
2022Targeting Kinase Inhibitor Induced Signaling Plasticity in Patients with Ph-Like ALL1K22CA251649-01HURTZ, CHRISTIANTEMPLE UNIV OF THE COMMONWEALTH, PA$193,104NCI
2022The DF phospho-code regulating the degradation of m6A mRNA1K22CA258954-01ZACCARA, SARACOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$192,456ZCA1
2022The DAXX/ATRX/H3.3 axis in ERV regulation and tumor suppression1K22CA258674-01WASYLISHEN, AMANDA RIETTAUNIVERSITY OF CINCINNATI, OH$191,193ZCA1
2022Joint differentiation-state plasticity and genetic diversity modeling to predict response and improve efficacy of drug combination therapy1K22CA258799-01NIKOLOVA, OLGA HOREGON HEALTH & SCIENCE UNIVERSITY, OR$188,485ZCA1
2022Attacking aggressive p53 mutants in gynecologic cancer1K22CA263783-01THIEL, KRISTINA WUNIVERSITY OF IOWA, IA$186,840ZCA1
2022Phase Separation-involved Roles of Mediator Complex in Myc-amplified Cancer1K22CA255404-01JIN, CHUNYUUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$185,760ZCA1
2022Identifying gut bacterial molecules and mechanisms that promote an anti-tumor response to immunotherapy1K22CA258960-01GAZZANIGA, FRANCESCA SMYLIEHARVARD MEDICAL SCHOOL, MA$184,656ZCA1
2022Dissecting the Functional Role of Monocytes in B-cell Acute Lymphoblastic Leukemia Survival1K22CA258520-01WITKOWSKI, MATTHEWUNIVERSITY OF COLORADO DENVER, CO$184,456ZCA1
2022Elucidating the regulation of RNA methylation by mTOR signaling in cancer1K22CA234399-01LEE, GINAUNIVERSITY OF CALIFORNIA-IRVINE, CA$182,226NCI
2022Admixture mapping of mosaic copy number alterations for identification of cancer drivers1K22CA258678-01JAKUBEK SWARTZLANDER, YASMINKA ALEKSANDRAUNIVERSITY OF KENTUCKY, KY$177,806ZCA1
2022DISSECTING THE ROLES OF FAT1 AND NEAT1 IN SOFT TISSUE SARCOMA DEVELOPMENT AND METASTASIS USING NOVEL IN VIVO SARCOMA MODELS1K22CA248849-01HUANG, JIANGUOPROVIDENCE HEALTH & SERVICES - OREGON, WA$162,000NCI
2022Contribution of the Inflammasome to Radiation Response in Pancreatic Cancer1K22CA251643-01A1MEDLER, TERRY RPROVIDENCE PORTLAND MEDICAL CENTER, OR$162,000ZCA1
2022Cellular and microenvironmental mechanisms linking aging to tumor control1K22CA266150-01RINGEL, ALISON EPSTEINMASSACHUSETTS GENERAL HOSPITAL, MA$162,000ZCA1
2022Intratumoral immunotherapy to enhance T cell infiltration and augment immune checkpoint blockade responses across molecular subtypes of breast cancer1K22CA262340-01CROSBY, ERIKA JDUKE UNIVERSITY, NC$161,486ZCA1
2022The role of SMARCAL1 in glioma telomere maintenance.1K22CA258965-01A1WAITKUS, MATTHEWDUKE UNIVERSITY, NC$152,141ZCA1
2022Identifying Novel Intensity-Specific Regulators of RAS Signaling1K22CA266753-01KABIRI, ZAHRADUKE UNIVERSITY, NC$133,907ZCA1
2021Investigating the biology and therapeutic vulnerabilities of ER+ metastatic breast cancer with activating HER2 mutations1K22CA241377-01A1NAYAR, UTTHARAJOHNS HOPKINS UNIVERSITY, MD$195,220NCI
2021Investigation of the mitochondrial function in GNAS mutant neoplasms1K22CA237817-01PATRA, KRUSHNA CHANDRAUNIVERSITY OF CINCINNATI, OH$195,196NCI
2021Tumor-directed immunostimulatory nanoparticles for novel 'prime-pull'cancer vaccination1K22CA262355-01ATUKORALE, PRABHANIUNIVERSITY OF MASSACHUSETTS AMHERST, MA$194,524ZCA1
2021Glycosylation as a Regulator of Tropism of Melanoma Metastasis - Resubmission - 11K22CA229600-01A1AGRAWAL, PRAVEENALBERT EINSTEIN COLLEGE OF MEDICINE, NY$194,400NCI
2021Investigating the role of RUNX2 activation across cancer evolution in lung adenocarcinoma1K22CA258957-01LAFAVE, LINDSAY MARIEALBERT EINSTEIN COLLEGE OF MEDICINE, NY$194,400ZCA1
2021The immunosuppressive function of secretory IgM in tumor-bearing mice1K22CA248354-01TANG, CHIH-HANG ANTHONYMETHODIST HOSPITAL RESEARCH INSTITUTE, TX$194,184NCI
2021Anti-cancer therapeutic approaches for targeting the ALT telomere maintenance mechanism1K22CA245259-01A1MIN, JAEWONCOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$192,456NCI
2021Novel Molecular Functions of WEE1 in Esophageal Adenocarcinoma1K22CA255424-01CHEN, ZHENGUNIVERSITY OF MIAMI SCHOOL OF MEDICINE, FL$191,592ZCA1
2021Targeting abnormal immunomechanics in the glioblastoma microenvironment to improve therapeutic response1K22CA258410-01DATTA, MEENALUNIVERSITY OF NOTRE DAME, IN$191,052ZCA1
2021Mechanisms of epigenetic regulation of estrogen receptor function in breast cancer1K22CA245487-01A1TOSKA, ENEDAJOHNS HOPKINS UNIVERSITY, MD$187,800NCI
2021Mechanisms Of Akt Regulation1K22CA241105-01A1CHU, NAM KYOHIO STATE UNIVERSITY, OH$187,272NCI
2021Characterizing an alternatively spliced NTRK2 isoform in development and cancer1K22CA258953-01PATTWELL, SIOBHANSEATTLE CHILDREN'S HOSPITAL, WA$187,056ZCA1
2021Chemical Epigenomic Strategies to Overcome Metastatic Castration Resistant Prostate Cancer1K22CA255594-01GRYDER, BERKLEY ECASE WESTERN RESERVE UNIVERSITY, OH$175,095ZCA1
2021Unraveling the MALAT1 lncRNA-protein interaction networks that drive lung cancer metastasis1K22CA262349-01WEIDMANN, CHASE AUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$162,000ZCA1
2021A transcription-independent role of HSF1 in tumorigenesis via suppression of AMPK1K22CA248616-01SU, KUO-HUIUNIVERSITY OF TOLEDO HEALTH SCI CAMPUS, OH$161,962NCI
2021HPV alternative splicing in cervical cancer radiation response1K22CA237839-01A1ZHANG, JINWASHINGTON UNIVERSITY, MO$155,516NCI
2021Targeted disruption of the YAP/TAZ/TEAD axis in pancreatic cancer1K22CA258805-01NABET, BEHNAMFRED HUTCHINSON CANCER RESEARCH CENTER, WA$110,651ZCA1
2020A Molecular Study of Rag GTPase-Dependent Amino Acid Sensing1K22CA241362-01SHEN, KUANGUNIV OF MASSACHUSETTS MED SCH WORCESTER, MA$204,163NCI
2020Pathological epigenetic hyper-plasticity promotes acquisition of pro-tumor states in cancer1K22CA237846-01A1FLAVAHAN, WILLIAM ALEXANDERUNIV OF MASSACHUSETTS MED SCH WORCESTER, MA$200,409NCI
2020Functional Approaches to Understanding Cancer Aneuploidy: Interrogating the Effects of Chromosome 3p Deletion1K22CA237733-01TAYLOR, ALISON M.COLUMBIA UNIVERSITY HEALTH SCIENCES, NY$192,456NCI
2020Enhanced Immunotherapy by Targeting the Pros1:Macrophage Mer Axis1K22CA237742-01UBIL, ERIC SUNIVERSITY OF ALABAMA AT BIRMINGHAM, AL$192,352NCI
2020Identifying driver non-coding alterations in metastatic prostate cancer from tumor and cell-free DNA1K22CA237746-01HA, GAVINFRED HUTCHINSON CANCER RESEARCH CENTER, WA$189,432NCI
2020Oncogenic Roles and Therapeutic Potential of MCL1 Addiction in Primary Effusion Lymphoma1K22CA241355-01A1MANZANO, MARKUNIV OF ARKANSAS FOR MED SCIS, AR$183,707NCI
2020Targeting ANGPTL4 in obesity-driven breast cancer progression1K22CA229595-01A1KOLB, RYAN HUNIVERSITY OF FLORIDA, FL$179,714NCI
2020Metabolic and epigenetic drivers of stem cells in obesity and cancer1K22CA241083-01MANA, MIYEKOARIZONA STATE UNIVERSITY-TEMPE CAMPUS, AZ$177,149NCI
2020The role of PP2A B56a in pancreatic tumorigenesis1K22CA237620-01A1ALLEN-PETERSEN, BRITTANYPURDUE UNIVERSITY, IN$174,844NCI
2020TET-mediated Epigenetic Regulation in the Development and Immunoevasion of B cell Lymphoma1K22CA241290-01LIO, JERRY CHAN-WANGOHIO STATE UNIVERSITY, OH$161,751NCI
2020Myeloid Syk promotes tumor immunosuppression and inhibits anti-tumor adaptive immunity1K22CA229594-01A1JOSHI, SHWETAUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$161,230NCI
2020Characterizing and targeting intra-tumor heterogeneity in triple negative breast cancer chemoresistance and multi-organ metastasis1K22CA241113-01ECHEVERRIA, GLORIA VITTONEBAYLOR COLLEGE OF MEDICINE, TX$157,680NCI
2020ROLE OF MIDKINE IN MOLECULAR TARGETED THERAPY TO TIP1 FOR LUNG CANCER TREATMENT1K22CA234404-01A1KAPOOR, VAISHALIWASHINGTON UNIVERSITY, MO$153,211NCI
2019Improving shared decision making in cancer screening1K22CA234400-01A1CARLSSON, SIGRIDSLOAN-KETTERING INST CAN RESEARCH, NY$198,064NCI
2019Targeting altered nitrogen metabolism in an aggressive subset of human lung cance1K22CA226676-01A1KIM, JIYEONUNIVERSITY OF ILLINOIS AT CHICAGO, IL$197,082NCI
2019Overcoming barriers to cancer screening among women living in rural and segregated communities1K22CA225705-01A1MOSS, JENNIFER LINDSAYPENNSYLVANIA STATE UNIV HERSHEY MED CTR, PA$194,944NCI
2019High-Throughput Functional Genomics to Guide Precision Oncology in Gastrointestinal Tumors1K22CA234406-01SHEN, JOHN PAUL YING CHINGUNIVERSITY OF TX MD ANDERSON CAN CTR, TX$192,240NCI
2019Use of Physiologic Media to Study Metabolic Regulation and Requirements in Cancer1K22CA225864-01A1CANTOR, JASON ROBERTMORGRIDGE INSTITUTE FOR RESEARCH, INC., WI$189,797NCI
2019Novel Approaches to Modeling and Treating IDH1 Mutant Glioma1K22CA237752-01MCBRAYER, SAMUEL KENTUT SOUTHWESTERN MEDICAL CENTER, TX$177,473NCI
2019Nuclear body assembly and function in telomerase-free cancer cells1K22CA237632-01ZHANG, HUAIYINGCARNEGIE-MELLON UNIVERSITY, PA$166,088NCI

Data: Grants.gov's daily extract and NIH's notice pages and award files, in ScienceGraph release conductgrants-2026-11-09-0.1.0. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.

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