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NIH funding notice PAR-18-763

Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Development and Validation of Model Systems and/or Pharmacodynamic Markers to Facilitate Neurotherapeutic Discovery (R61/R33 Clinical Trial Not Allowed)

Closed on March 12, 2021.

Posted
April 19, 2018
Close date
March 12, 2021
Activity codes
R61, R33
Institutes taking part
Not stated on the notice page

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

  1. Reissues: RFA-NS-16-013 Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Development and Validation of Model Systems and/or Pharmacodynamic Markers to Facilitate the Discovery of Neurotherapeutics (R21/R33)

Replaced by PAR-21-123.

Who won it before

12 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $5,329,977 in first-year total cost, median $399,319.

Most frequent study sections

  1. Neurological Sciences and Disorders B Study Section[NSD-B]7
  2. Neurological Sciences and Disorders A Study Section[NSD-A]5

Most frequent institutions

  1. BAYLOR COLLEGE OF MEDICINE1
  2. IOWA STATE UNIVERSITY1
  3. MASSACHUSETTS GENERAL HOSPITAL1
  4. MICHIGAN STATE UNIVERSITY1
  5. NEW YORK UNIVERSITY SCHOOL OF MEDICINE1
Competing awards under PAR-18-763 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2022A Phenotype-Optimized Zebrafish Model of Progressive Supranuclear Palsy1R61NS125280-01BURTON, EDWARD ALANSCHOPPIK, DAVIDNEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY$497,436NSD
2020iPSC-derived neurovascular tissue model of cerebral amyloiad angiopathy1R61NS112445-01A1LIPPMANN, ETHANVANDERBILT UNIVERSITY, TN$831,660NSD
2020Development and Validation of a Clinically Relevant Animal Pain Model1R61NS116423-01SHEN, SHIQIANMASSACHUSETTS GENERAL HOSPITAL, MA$420,000NSD
2020Modeling West Syndrome to Prevent Neurobehavioral Disabilities1R61NS112553-01A1SWANN, JOHN WILLIAMBAYLOR COLLEGE OF MEDICINE, TX$400,938NSD
2019Combining synucleinopathy and mitochondrial deficits in a novel mouse model of Parkinsons disease1R21NS106078-01A1 · under RFA-NS-16-013BRUNDIN, PATRIKKORDOWER, JEFFREY HVAN ANDEL RESEARCH INSTITUTE, MI$471,170NSD
2019Development and Validation of a Zebrafish Model for Vanishing White Matter Disease1R21NS109441-01 · under RFA-NS-16-013BONKOWSKY, JOSH LEITCHUNIVERSITY OF UTAH, UT$376,556NSD
2019Validation of a novel mouse model of temporal lobe epilepsy1R61NS112549-01PEREZ-REYES, EDWARDUNIVERSITY OF VIRGINIA, VA$363,375NSD
2018Internal and external validation of a porcine dystrophinopathy model1R21NS106112-01 · under RFA-NS-16-013SELSBY, JOSHUA TIOWA STATE UNIVERSITY, IA$341,138NSD
2017Development and validation of a genetically engineered model of neurofibromatosis type 2 to facilitate discovery of neurotherapeutics1R21NS099417-01A1 · under RFA-NS-16-013KISSIL, JOSEPHSCRIPPS FLORIDA, FL$477,230NSD
2017The Rat Pre-Formed Alpha-Synuclein Fibril Model of Parkinson's Disease1R21NS099416-01A1 · under RFA-NS-16-013SORTWELL, CARYL EMICHIGAN STATE UNIVERSITY, MI$397,700NSD
2017Innovation Grant to Nurture Initial Translational Efforts (IGNITE) to Neurotherapeutic Approaches in Minipig Models of PKU Disorders1R21NS099450-01A1 · under RFA-NS-16-013DOBROWOLSKI, STEVEN FNICHOLLS, ROBERT DUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$383,610NSD
2017New GAA expansion mouse for efficacy studies of treatments for Friedreich ataxia1R21NS101145-01 · under RFA-NS-16-013NAPIERALA, MAREKUNIVERSITY OF ALABAMA AT BIRMINGHAM, AL$369,164NSD

Data: Grants.gov's daily extract and NIH's notice pages and award files, in ScienceGraph release conductgrants-2026-11-09-0.1.0. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.

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