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NIH funding notice PAR-19-146

Drug Discovery For Nervous System Disorders (R21 Clinical Trial Not Allowed)

Closed on January 7, 2022.

Posted
January 8, 2019
Close date
January 7, 2022
Activity codes
Not stated on the notice page
Institutes taking part
Not stated on the notice page

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

Its page was not saved, so the notices it replaced are not known.

Who won it before

12 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $4,094,511 in first-year total cost, median $423,400.

Most frequent study sections

  1. Drug Discovery for the Nervous System Study Section[DDNS]12

Most frequent institutions

  1. UNIVERSITY OF CALIFORNIA LOS ANGELES3
  2. PURDUE UNIVERSITY2
  3. UNIV OF NORTH CAROLINA CHAPEL HILL2
  4. DARTMOUTH COLLEGE1
  5. EMORY UNIVERSITY1
Competing awards under PAR-19-146 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2022Identification of CNS-Penetrant Tryptophan 2,3-Dioxygenase Degrading Ligands1R21AG078775-01ALTMAN, RYAN ALIU, AIMINPURDUE UNIVERSITY, IN$235,901DDNS
2021Use of Bioinformatics and Genetics to Identify a New Class of Drugs for Neurological Disease1R21AG072142-01MYERS, SCOTT JAMESEMORY UNIVERSITY, GA$425,269DDNS
2021Screening for enhancers of secreted clusterin (sCLU) and evaluation in AD models1R21AG072150-01JOHN, VARGHESEUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$423,400DDNS
2021Screening for Compounds that Lower Intracellular Alpha-Synuclein Levels1R21AG063007-01A1JOHN, VARGHESEUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$423,400DDNS
2021Negative allosteric modulators of the D3 dopamine receptor as therapeutic leads for substance use disorders1UG3DA050820-01A1FRANKOWSKI, KEVIN J.UNIV OF NORTH CAROLINA CHAPEL HILL, NC$233,250DDNS
2021Small molecule inhibitors of hyperphosphorylated tau aggregation and cytotoxicity for the development of Alzheimer’s therapeutics1R21AG070447-01A1FORTIN, JESSICAPURDUE UNIVERSITY, IN$220,488DDNS
2021D1 dopamine receptor positive allosteric modulators as a practical treatment for cognitive decline1R21AG068833-01A1FRANKOWSKI, KEVIN J.UNIV OF NORTH CAROLINA CHAPEL HILL, NC$194,375DDNS
2020Chimeric antigen receptor T regulatory cells as therapy for Alzheimer's Disease1R21AG067971-01SENTMAN, CHARLES L.DARTMOUTH COLLEGE, NH$451,000DDNS
2020Novel Wnt activators for Alzheimer's disease therapy1R21AG065653-01A1LI, YONGHEMAYO CLINIC JACKSONVILLE, FL$430,375DDNS
2020Screening for SORLA enhancers and evaluation in AD models1R21AG067461-01JOHN, VARGHESEUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$429,000DDNS
2020Development of Novel ERRa Selective Agonists as Chemical Probes for the Potential Treatment of Alzheimer's Disease1R21AG065657-01ELGENDY, BAHAAST. LOUIS COLLEGE OF PHARMACY, MO$426,553DDNS
2020Low-Efficacy Dopamine D4 Receptor Partial Agonists for Cocaine Addiction1R21DA050896-01A1BOATENG, COMFORT AHENKANKECK, THOMAS MCGOWANHIGH POINT UNIVERSITY, NC$201,500DDNS

Data: Grants.gov's daily extract and NIH's notice pages and award files, in ScienceGraph release conductgrants-2026-11-09-0.1.0. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.

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PAR-19-146: Drug Discovery For Nervous System Disorders (R21 Clinical Trial Not Allowed) | ScienceDex | ConductScience