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NIH funding notice PAR-19-147

Drug Discovery For Nervous System Disorders (R01 Clinical Trials Not Allowed)

Closed on January 7, 2022.

Posted
January 8, 2019
Close date
January 7, 2022
Activity codes
Not stated on the notice page
Institutes taking part
Not stated on the notice page

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

Its page was not saved, so the notices it replaced are not known.

Who won it before

22 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $18,204,658 in first-year total cost, median $767,002.

Most frequent study sections

  1. Drug Discovery for the Nervous System Study Section[DDNS]21
  2. Drug Discovery for the Nervous System Study Section[DDNS-R]1

Most frequent institutions

  1. JOHNS HOPKINS UNIVERSITY3
  2. EMORY UNIVERSITY2
  3. MASSACHUSETTS GENERAL HOSPITAL2
  4. SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE2
  5. CLEVELAND CLINIC LERNER COM-CWRU1
Competing awards under PAR-19-147 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2022PET ligand discovery for arginine vasopressin1R01MH128705-01LIANG, STEVEN HEMORY UNIVERSITY, GA$1,043,141DDNS
2022Preventing Tau uptake by novel inhibitors of tau binding to LRP11R01AG075084-01JACKSON, MICHAELKOSIK, KENNETH STEPHENUNIVERSITY OF CALIFORNIA SANTA BARBARA, CA$885,722DDNS
2022Subtype-selective NMDA ligands for Alzheimer's Disease1R01AG075444-01LIANG, STEVEN HEMORY UNIVERSITY, GA$782,248DDNS
20225-HT2 Receptor Allosterism in Cocaine Use Disorder2R01DA038446-06A1CUNNINGHAM, KATHRYN A.ZHOU, JIAUNIVERSITY OF TEXAS MED BR GALVESTON, TX$537,543DDNS
2022Macrophage-targeted dendrimer 2-PMPA for the treatment of age-related sarcopenia1R01AG078181-01HOKE, AHMETRANGARAMANUJAM, KANNANSLUSHER, BARBARA STAUCHJOHNS HOPKINS UNIVERSITY, MD$476,442DDNS
2022Discovery of apoE4 modulators for Alzheimer’s disease therapy1R01AG078615-01CHUNG, THOMAS D YLI, YONGHEMAYO CLINIC JACKSONVILLE, FL$467,938DDNS
2022Novel GLT-1 activators for the treatment of alcohol dependence: preclinical studies1R01AA029674-01A1ABOU-GHARBIA, MAGIDSARI, YOUSSEFUNIVERSITY OF TOLEDO HEALTH SCI CAMPUS, OH$437,019DDNS
2021Discovery of functionally selective dopamine ligands for age-related cognitive decline1RF1AG071675-01DOKHOLYAN, NIKOLAYMAILMAN, RICHARD BYANG, YANGPENNSYLVANIA STATE UNIV HERSHEY MED CTR, PA$1,464,036DDNS
2021cGAS inhibitors for Alzheimer's disease treatment1R01AG074541-01GAN, LISINHA, SUBHASH CWEILL MEDICAL COLL OF CORNELL UNIV, NY$847,498DDNS
2021Ligand discovery for delineating cholesterol homeostasis in the brain1R01AG070060-01LIANG, STEVEN HMASSACHUSETTS GENERAL HOSPITAL, MA$808,990DDNS
2021A Cytochrome P450 Therapeutic Space for Tauopathies1R56AG066712-01A1CAGAN, ROSS LEIGHDAR, ARVINICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY$801,925DDNS
2021AMPAR ligand discovery for Alzheimer's disease1RF1AG073428-01LIANG, STEVEN HMASSACHUSETTS GENERAL HOSPITAL, MA$384,165DDNS
2020Identification of small molecule inhibitors of tau pathology utilizing a novel primary neuronal assay.1RF1AG066569-01BRUNDEN, KURT R.UNIVERSITY OF PENNSYLVANIA, PA$2,245,547DDNS
2020Novel Antagonists of the N-terminal Domain of the CRF Receptor Type 1 for Alzheimer's Disease1RF1AG065385-01RISSMAN, ROBERTVETERANS MEDICAL RESEARCH FDN/SAN DIEGO, CA$1,728,235DDNS
2020Development of STEP Allosteric Inhibitors as Novel Therapeutics for Alzheimer's Disease1R01AG065387-01A1TAUTZ, LUTZSANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE, CA$958,279DDNS
2020Pro-Electrophilic Drugs PEDs for Alzheimer's Disease1R56AG065372-01LIPTON, STUART ASCRIPPS RESEARCH INSTITUTE, THE, CA$885,611DDNS
2020Discovery of Selective Inhibitors for the EphA4 Kinase1R01AG062617-01A1PASQUALE, ELENA BSERGIENKO, EDUARD A.SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE, CA$751,756DDNS
2020Development of mGlu7 receptor allosteric modulators for neurological and psychiatric disorders1R01MH124671-01LINDSLEY, CRAIGNISWENDER, COLLEEN MVANDERBILT UNIVERSITY, TN$741,117DDNS
2020Development of GCPII inhibitors for the treatment of age-related cognitive disorders1R01AG068130-01ARNSTEN, AMY F.T.SLUSHER, BARBARA STAUCHTSUKAMOTO, TAKASHIJOHNS HOPKINS UNIVERSITY, MD$720,931DDNS
2020Non-beta-lactam GLT-1 activators: characterization in preclinical models of opioid and cocaine addiction1R01DA051205-01RAWLS, SCOTT M.REITZ, ALLEN BTEMPLE UNIV OF THE COMMONWEALTH, PA$455,516DDNS
2020Early Stage Studies of a Novel Positive Allosteric Modulator of the Alpha1-Adrenergic Receptor to Treat Alzheimer's Disease1R01AG066627-01PEREZ, DIANNE MCLEVELAND CLINIC LERNER COM-CWRU, OH$402,083DDNS
2020Dendrimer-conjugated nSMase2 inhibitor as a novel therapeutic approach for Alzheimer's Disease1R01AG063831-01A1RAIS, RANARANGARAMANUJAM, KANNANSLUSHER, BARBARA STAUCHJOHNS HOPKINS UNIVERSITY, MD$378,916DDNS

Data: Grants.gov's daily extract and NIH's notice pages and award files, in ScienceGraph release conductgrants-2026-11-09-0.1.0. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.

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