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NIH funding notice PAR-19-365

Limited Competition: Small Grant Program for NIDDK K01/K08/K23/K25 Recipients (R03 Clinical Trial Optional)

Closed on September 7, 2022.

Posted
September 9, 2019
Close date
September 7, 2022
Activity codes
R03
Institutes taking part
NIDDK

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

  1. Reissues: PAR-18-103 Limited Competition: Small Grant Program for NIDDK K01/K08/K23 Recipients (R03 Clinical Trial Optional)
  2. 2 steps back: PAR-16-148 Limited Competition: Small Grant Program for NIDDK K01/K08/K23 Recipients (R03)
  3. 3 steps back: PAR-15-343 Limited Competition: Small Grant Program for NIDDK K01/K08/K23 Recipients (R03)
  4. 4 steps back: PAR-12-285 Limited Competition: Small Grant Program for NIDDK K01/K08/K23 Recipients (R03)
  5. 5 steps back: PAR-09-230 Small Grant Program for NIDDK K01/K08/K23 Recipients (R03)
  6. 6 steps back: PAR-06-172 Small Grant Program for NIDDK K08/K23 Recipients (R03)
  7. 7 steps back: PAR-04-070

Replaced by PAR-22-129.

Who won it before

304 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $29,990,025 in first-year total cost, median $94,500.

Most frequent study sections

  1. Digestive Diseases and Nutrition C Study Section[DDK-C]119
  2. Diabetes, Endocrinology and Metabolic Diseases B Study Section[DDK-B]87
  3. Kidney, Urologic and Hematologic Diseases D Study Section[DDK-D]72
  4. Special Emphasis Panel[ZDK1 GRB-G (M2)]5
  5. Diabetes, Endocrinology and Metabolic Diseases B Study Section[DDK-B (M1)]4

Most frequent institutions

  1. MASSACHUSETTS GENERAL HOSPITAL15
  2. MAYO CLINIC ROCHESTER13
  3. UNIVERSITY OF COLORADO DENVER12
  4. UNIVERSITY OF ALABAMA AT BIRMINGHAM11
  5. UNIVERSITY OF PITTSBURGH AT PITTSBURGH10
Competing awards under PAR-19-365 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2023The role of SH2B3 in regulating CD8 T cells in Type 1 Diabetes1R03DK134746-01ALLENSPACH, ERIC JSEATTLE CHILDREN'S HOSPITAL, WA$147,675DDK
2023The Role of Pretransplant Services on Outcomes and Costs in Kidney Transplantation1R03DK134795-01CHENG, XINGXING SHELLEYSTANFORD UNIVERSITY, CA$131,513DDK
2023Iron homeostasis and monocyte differentiation in patients with chronic kidney disease1R03DK135897-01AKCHURIN, OLEHWEILL MEDICAL COLL OF CORNELL UNIV, NY$127,125DDK
2023Blood Protein Markers of Biologic Treatment Response in Crohn's Disease1R03DK132440-01A1UNGARO, RYANICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY$126,750DDK
2023Developing imaging nanoprobes to advance prognosis of kidney fibrosis1R03DK134791-01XU, LEYUANYALE UNIVERSITY, CT$125,625ZDK1
2023Therapeutic rescue of Polycystin-1 protein expression by targeting PKD1 upstream open reading frames1R03DK134793-01BESSE, WHITNEY ELISEYALE UNIVERSITY, CT$125,625DDK
2023Role of Psychological Processes on Symptom Burden in Laryngopharyngeal Reflux1R03DK135513-01YADLAPATI, RENA HIRENUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$125,074DDK
2023High resolution characterization of epigenetic dynamics in gastrointestinal cell plasticity1R03DK134799-01JADHAV, UNMESHUNIVERSITY OF SOUTHERN CALIFORNIA, CA$123,750DDK
2023Elucidating mechanisms of fibrosis associated with the Crohns disease-associated pathogenic variant in the metal transporter ZIP81R03DK134595-01MELIA, JOANNA MILLER PELOQUINJOHNS HOPKINS UNIVERSITY, MD$122,813DDK
2023Design and Pilot Test of A Prediabetes Digital Patient Activation Tool1R03DK135898-01TSENG, EVAJOHNS HOPKINS UNIVERSITY, MD$122,813DDK
2023Bacterial mediators of postnatal growth in preterm infants1R03DK134684-01YOUNGE, NOELLE ELIZABETHDUKE UNIVERSITY, NC$120,750DDK
2023Regulation of Adipose Tissue Remodeling Through Axon Guidance Molecule Slit31R03DK135786-01SHAMSI, FARNAZNEW YORK UNIVERSITY, NY$120,594DDK
2023Lipocalin-2, a mitokine that mediates white to brown fat crosstalk1R03DK135783-01AN, YUUNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON, TX$117,000DDK
2023Cellular crosstalk regulating cholangiocyte proliferation following extrahepatic bile duct injury1R03DK135893-01RAZUMILAVA, NATALIYAUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$117,000DDK
2023Immune-Metabolic Regulation of Biliary Atresia1R03DK135784-01TAYLOR, SARAH ANNUNIVERSITY OF COLORADO DENVER, CO$116,625DDK
2022Role of antigen-specific T cells in immunotherapy-associated acute interstitial nephritis and kidney allograft rejection1R03DK131223-01MURAKAMI, NAOKABRIGHAM AND WOMEN'S HOSPITAL, MA$134,250DDK
2022Age-specific differentiation of multipotent progenitors1R03DK126729-01A1ROWE, ROBERT GRANTBOSTON CHILDREN'S HOSPITAL, MA$132,750DDK
2022Study of Pathway-Dependent Effects of Luminal Microbial Metabolites Including Short Chain Fatty Acids and Bile Acids in Irritable Bowel Syndrome Through Meta-omics Analysis of Fecal Specimens1R03DK132446-01SHIN, ANDREAINDIANA UNIVERSITY INDIANAPOLIS, IN$132,535DDK
2022Identifying genetic regulators of hepatic reductive stress in diversity outbred mice1R03DK131243-01GOODMAN, RUSSELL PAULMASSACHUSETTS GENERAL HOSPITAL, MA$129,893DDK
2022Creation and Testing of an Education Decision Aid for Colectomy in Recurrent Diverticulitis1R03DK129559-01A1HAWKINS, ALEXANDER THARRINGTONVANDERBILT UNIVERSITY MEDICAL CENTER, TN$129,750DDK
2022Development of a Robust Strategy for Living Kidney Donor Follow-up and Engagement1R03DK132222-01LEVAN, MACEY LEIGHNEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY$127,125DDK
2022Extension of Type 2 Diabetes Genetic Clustering to Populations of non-European Ancestry1R03DK131249-01UDLER, MIRIAM SARGONMASSACHUSETTS GENERAL HOSPITAL, MA$126,000DDK
2022Metabolomic Investigation of the Impact of Growth Hormone on Nonalcoholic Fatty Liver Disease: Identification of Novel Biomarkers and Therapeutic Targets1R03DK129635-01A1DICHTEL, LAURA ELISABETHMASSACHUSETTS GENERAL HOSPITAL, MA$126,000DDK
2022ROLE OF CIRCADIAN RHYTHM AND INTERMITTENT DOSING IN MUSCLE TRIGLYCERIDE LIPASE INDUCTION BY GLUCOCORTICOIDS1R03DK130908-01A1QUATTROCELLI, MATTIACINCINNATI CHILDRENS HOSP MED CTR, OH$125,906ZDK1
2022Cellular Interactions in Vascular Calcification of Chronic Kidney Disease1R03DK131246-01A1CHEN, WEIALBERT EINSTEIN COLLEGE OF MEDICINE, NY$125,320DDK
2022Comparing Dialysis Provision and Outcomes Between Medicare Advantage and Fee-for-Service Medicare1R03DK131239-01LIN, EUGENEUNIVERSITY OF SOUTHERN CALIFORNIA, CA$123,750DDK
2022Targeting Cell Death Pathways in Immune-mediated Liver Injury from Checkpoint Inhibitors1R03DK132437-01DARA, LILYUNIVERSITY OF SOUTHERN CALIFORNIA, CA$123,750DDK
2022Calibrating and validating accelerometry for use across early childhood (6-24 months)1R03DK131154-01EMOND, JENNIFER A.DARTMOUTH COLLEGE, NH$123,000DDK
2022Ceramide, AMPK, and YAP/TAZ Signaling in Hepatic Fibrogenesis1R03DK131222-01CHEN, JENNIFER Y.UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$121,125DDK
2022Influence of Androgens on Tissue-Specific Lipid Metabolites and Liver Injury in Young Women with NAFLD1R03DK131238-01SARKAR, MONIKAUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$121,125DDK
2022Associations of Targeted Metabolites with Protein, Saturated Fat and Glucose Homeostasis1R03DK132307-01GADGIL, MEGHANA DIPTIUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$121,125ZDK1
2022Regulation of methionine metabolism in NASH by PPARgamma1R03DK129419-01A1CORDOBA-CHACON, JOSEUNIVERSITY OF ILLINOIS AT CHICAGO, IL$119,925DDK
2022Impact of abnormal steroid metabolome on cellular senescence, frailty and cognition1R03DK132121-01BANCOS, IRINAMAYO CLINIC ROCHESTER, MN$119,250DDK
2022Elucidating the role of ATF6α as a critical pro-fibrogenic transcription factor in Hepatic Stellate Cells1R03DK129326-01A1MAIERS, JESSICA LINDIANA UNIVERSITY INDIANAPOLIS, IN$118,875DDK
2022SWING LIGAND-REGULATED ENHANCER-DEPENDENT TRANSCRIPTION1R03DK129217-01A1MELUZZI, DARIOUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$118,500DDK
2022Role of the MUC1/HIF-1a Complex in the kidney proximal tubule during ischemia-reperfusion injury.1R03DK131093-01AL-BATAINEH, MOHAMMADUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$118,158DDK
2022The Role of CREBRF on Hypothalamic Function1R03DK131224-01FRAHM, KRYSTLE ANNEUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$118,157DDK
2022Deciphering the source and consequences of Nur77 expression during E. coli rUTI in mice1R03DK132442-01GILBERT, NICOLE MARIEWASHINGTON UNIVERSITY, MO$118,125DDK
2022Regulation of the double-stranded RNA (dsRNA) response in gastric metaplasia and dysplasia1R03DK133423-01SAENZ, JOSE BERNARDOWASHINGTON UNIVERSITY, MO$117,998DDK
2022Mechanisms of ketosis and near-normoglycemia remission in obese African Americans with ketosis-prone diabetes1R03DK129627-01A1VELLANKI, PRIYATHAMAEMORY UNIVERSITY, GA$117,375DDK
2022Genomic strategies to identify novel gene regulatory mechanisms by ligand-activated transcriptional enhancers1R03DK131250-01NAIR, SREEJITH JANARDHANANGEORGETOWN UNIVERSITY, DC$117,000DDK
2022cerebrovascular reactivity in adults on hemodialysis and association with intradialytic cerebral hypoperfusion1R03DK132441-01WOLFGRAM, DAWN F.MEDICAL COLLEGE OF WISCONSIN, WI$117,000DDK
2022Examining a mechanism for insulin resistance in short sleeping adolescents: Melatonin, food intake, and the role of a melatonin receptor gene variant (MTNR1B)1R03DK131225-01A1SIMON, STACEY LYNNUNIVERSITY OF COLORADO DENVER, CO$116,625DDK
2022Developmental Infant Effects of Exposure to High Doses of Oral Insulin in Human Milk (HM)1R03DK131219-01YOUNG, BRIDGET VICTORIAUNIVERSITY OF ROCHESTER, NY$115,500DDK
2022Diabetes Timing and Types and the Effect on Beta Cell Function Post-Acute Pancreatitis in Children1R03DK131156-01ABU-EL-HAIJA, MAISAMCINCINNATI CHILDRENS HOSP MED CTR, OH$113,728DDK
2022Improving the Diagnosis and Fibrosis Risk Assessment of Nonalcoholic Fatty Liver Disease in Primary Care Patients with Abnormal Liver Chemistries1R03DK129558-01A1SCHREINER, ANDREW DAVIDMEDICAL UNIVERSITY OF SOUTH CAROLINA, SC$113,188ZDK1
2022Effects of semaglutide on bone and muscle endpoints in adults with obesity: a pilot study.1R03DK131155-01HAINES, MELANIE SCHORRMASSACHUSETTS GENERAL HOSPITAL, MA$112,264DDK
2022Non-invasive, longitudinal assessment of adipocyte size during the pathogenesis of type 2 diabetes1R03DK128528-01A1BEEMAN, SCOTT CHARLESARIZONA STATE UNIVERSITY-TEMPE CAMPUS, AZ$107,264DDK
2022Ing4-deficiency enhances the regenerative capacity of multipotent progenitor cells1R03DK124738-01A1KATHREIN, KATIE LUNIVERSITY OF SOUTH CAROLINA AT COLUMBIA, SC$106,274DDK
2022Role of Testosterone Induction of Hydrogen Sulfide in Erectile Dysfunction1R03DK131242-01LAFAVOR, JUSTIN DAVIDFLORIDA STATE UNIVERSITY, FL$105,183DDK
2022Expanding the Diabetes Homelessness Medication Support (D-Homes) program to Spanish speaking Hispanics1R03DK133553-01VICKERY, KATHERINE DIAZHENNEPIN HEALTHCARE RESEARCH INSTITUTE, MN$97,176DDK
2022Brain-gut-immune Profiling in Connective Tissue Disorder-related Gastrointestinal Dysfunction1R03DK131221-01KARRENTO, KATJA KRISTINAMEDICAL COLLEGE OF WISCONSIN, WI$95,196ZDK1
2022Feasibility and effectiveness of a pilot remote monitoring program for the treatment of diabetic foot ulcers1R03DK133557-01HICKS, CAITLIN WHITNEYJOHNS HOPKINS UNIVERSITY, MD$94,500DDK
2022Motivating parental support of youth skill-building during health care transition1R03DK132439-01WISK, LAUREN ELISABETHUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$93,594DDK
2021Testing the usability of a web-based hypospadias decision aid for parents using a user-centered design approach1R03DK126843-01CHAN, KATHERINE HUBERTUNIV OF NORTH CAROLINA CHAPEL HILL, NC$132,750DDK
2021The Role of CCL5 in Hematopoietic Stem Cell Activation and Skewing1R03DK124746-01A1MACHLUS, KELLIE RAEBOSTON CHILDREN'S HOSPITAL, MA$132,750DDK
2021Regulation of energy and glucose homeostasis by endogenous hypothalamic FGF11R03DK128383-01SCARLETT, JARRAD MUNIVERSITY OF WASHINGTON, WA$132,375DDK
2021Role of miR-6236 in Obesity-Associated Adipose Tissue Dysfunction1R03DK129418-01HILL, DAVID ANDREWCHILDREN'S HOSP OF PHILADELPHIA, PA$132,000DDK
2021Phosphorylation of the podocyte cytoskeleton in diabetic nephropathy1R03DK129637-01FENG, DIBETH ISRAEL DEACONESS MEDICAL CENTER, MA$131,250DDK
2021MOVE: MOtiVational Strategies To Empower African Americans To Improve Dialysis Adherence1R03DK129626-01UMEUKEJE, EBELE MVANDERBILT UNIVERSITY MEDICAL CENTER, TN$129,750DDK
2021Multi-parametric MRI of ARPKD liver disease1R03DK127132-01HARTUNG, ERUM AFTABCHILDREN'S HOSP OF PHILADELPHIA, PA$126,193DDK
2021Metabolomics of symptomatic gallstone disease in COMETS1R03DK127148-01JOSHI, AMIT DOLARMASSACHUSETTS GENERAL HOSPITAL, MA$126,000DDK
2021Effect of Covid-19 on chronic kidney disease progression1R03DK128533-01SISE, MEGHAN E.MASSACHUSETTS GENERAL HOSPITAL, MA$126,000DDK
2021Brain Inhibition Control and Child Obesity Risk1R03DK129186-01LUO, SHANUNIVERSITY OF SOUTHERN CALIFORNIA, CA$123,750DDK
2021The formation of kidney local microenvironment after acute kidney injury.1R03DK128529-01ZHOU, DONGUNIVERSITY OF CONNECTICUT SCH OF MED/DNT, CT$123,000DDK
2021Metabolomic Markers of Dietary Factors Associated with Kidney Health1R03DK128386-01REBHOLZ, CASEY MARIEJOHNS HOPKINS UNIVERSITY, MD$122,813DDK
2021High-resolution mapping of the human brainstem during continence and micturition: noninvasive in vivo 7 Tesla fMRI study1R03DK126994-01KHAVARI, ROSEMETHODIST HOSPITAL RESEARCH INSTITUTE, TX$121,066DDK
2021Impaired bile acid synthesis due to CYP7A1 and CYP7B1 suppression in malnutrition1R03DK129495-01PREIDIS, GEOFFREY ABAYLOR COLLEGE OF MEDICINE, TX$120,375DDK
2021Evaluation of a New Method of Bilirubin Screening for Biliary Atresia1R03DK128535-01HARPAVAT, SANJIVBAYLOR COLLEGE OF MEDICINE, TX$120,000DDK
2021Regulation of adipose lineage plasticity in obesity1R03DK127149-01JIANG, YUWEIUNIVERSITY OF ILLINOIS AT CHICAGO, IL$119,925DDK
2021Designing a Mobile Obesity & Binge Eating Intervention for Implementation in Clinical Settings1R03DK128531-01GRAHAM, ANDREA KASSNORTHWESTERN UNIVERSITY AT CHICAGO, IL$119,500DDK
2021Community Paramedicine Program to Improve Diabetes Management among Adults Experiencing Severe Hypoglycemia1R03DK127010-01MCCOY, ROZALINA GRUBINAMAYO CLINIC ROCHESTER, MN$119,250DDK
2021Durability of Epithelial Defects in Crohn's Disease Intestine1R03DK124751-01A1VANDUSSEN, KELLI LYNNCINCINNATI CHILDRENS HOSP MED CTR, OH$119,250DDK
2021Digital Phenotyping of Nonalcoholic Fatty Liver Disease1R03DK128127-01ALLEN, ALINA MMAYO CLINIC ROCHESTER, MN$119,250DDK
2021The Pdx1-recruited Swi/Snf chromatin remodeling complex regulates endocrine cell expansion and differentiation in vivo1R03DK127129-01SPAETH, JASON MINDIANA UNIVERSITY INDIANAPOLIS, IN$118,875DDK
2021Construction of the ESKD Life Plan1R03DK127131-01WOO, KARENUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$117,000DDK
2021Spatial context of adipose tissue macrophages in obesity1R03DK129636-01MUIR, LINDSEY ALLISONUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$117,000DDK
2021WildCam: A Privacy Conscious Wearable Eating Detection Camera People will Actually Wear in the Wild1R03DK127128-01ALSHURAFA, NABILNORTHWESTERN UNIVERSITY AT CHICAGO, IL$116,737DDK
2021Complement as a modulator of immunosuppression and progression in Polycystic Kidney Disease1R03DK129414-01HOPP, KATHARINAUNIVERSITY OF COLORADO DENVER, CO$116,625DDK
2021Functional and Behavioral Characterization of Central Amygdala Glucagon Like Peptode-1 Receptors1R03DK129561-01HARDAWAY, JAMES ANDREWUNIVERSITY OF ALABAMA AT BIRMINGHAM, AL$111,375DDK
2021Predicting Short- and Long-term Risk of Serious Infections in Older Patients with Inflammatory Bowel Diseases1R03DK129631-01SINGH, SIDDHARTHUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$108,500DDK
2021Central melanin-concentrating hormone neural pathways and obesity1R03DK128306-01NOBLE, EMILY ELIZABETHUNIVERSITY OF GEORGIA, GA$106,500DDK
2021Assessment of Endogenous Oxalate Synthesis in Calcium Oxalate Kidney Stone Formers and Healthy Individuals1R03DK129497-01FARGUE, SONIAUNIVERSITY OF ALABAMA AT BIRMINGHAM, AL$99,735DDK
2021Impact of in utero diabetes exposure on miRNA: effects on cellular metabolism1R03DK125626-01A1TRYGGESTAD, JEANIE BEATRICEUNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR, OK$94,500DDK
2021T cell Trafficking in Uremic Cardiomyopathy1R03DK124736-01A1WINTERBERG, PAMELA DEMORY UNIVERSITY, GA$37,674DDK
2020Effects of Nutritional Ketosis on Brain Response to Hypoglycemia in People with Type One Diabetes Mellitus1R03DK123541-01 · under PAR-18-103LENNERZ, BELINDA SBOSTON CHILDREN'S HOSPITAL, MA$150,904DDK
2020Feeding regulation by cortical-amygdala circuits1R03DK124731-01 · under PAR-18-103YE, LISCRIPPS RESEARCH INSTITUTE, THE, CA$133,125DDK
2020Androgen Regulation of Colonic Motility1R03DK125636-01RAO, MEENAKSHIBOSTON CHILDREN'S HOSPITAL, MA$132,750DDK
2020Redox-mediated regulation of pattern-recognition-receptor signaling in intestinal epithelial cells1R03DK125630-01THIAGARAJAH, JAYBOSTON CHILDREN'S HOSPITAL, MA$132,750DDK
2020Carbonic Anhydrase 5A Dysfunction in Complex V Deficiency1R03DK125662-01GANETZKY, REBECCACHILDREN'S HOSP OF PHILADELPHIA, PA$132,000DDK
2020Investigating the Role of IL-23R in Mucosal Regulatory T Cells1R03DK123489-01A1GOETTEL, JEREMY ALLENVANDERBILT UNIVERSITY MEDICAL CENTER, TN$129,750DDK
2020Functional interrogation of host-microbial interactions in metabolic diseases1R03DK124742-01 · under PAR-18-103COHEN, LOUIS JAREDICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY$127,125DDK
2020Hepatocyte Hippo Signaling Drives Inflammation in Liver Injury and Regeneration1R03DK124743-01A1YIMLAMAI, DEANYALE UNIVERSITY, CT$125,625DDK
2020Control of Dendritic Cell Function by the Lipopolysaccharide (LPS)-Responsive and Beige-like Anchor protein (Lrba)1R03DK125631-01TURER, EMRE EROLUT SOUTHWESTERN MEDICAL CENTER, TX$122,563DDK
2020Elucidation of TNFR pathway components that regulate liver repopulation1R03DK123543-01 · under PAR-18-103WANGENSTEEN, KIRK JUNIVERSITY OF PENNSYLVANIA, PA$121,500DDK
2020The Cirrhosis Medical Home: A Feasibility Study1R03DK122230-01A1 · under PAR-18-103ORMAN, ERICINDIANA UNIVERSITY INDIANAPOLIS, IN$121,498DDK
2020The role of gut microbiota in regulating functional diversity of diet-responsive hypothalamic myeloid cells1R03DK125627-01VALDEARCOS, MARTINUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$121,125DDK
2020Role of regulatory T cell glucocorticoid-induced leucine zipper (GILZ) in the chronically inflamed intestine1R03DK123579-01A1GOODMAN, WENDY ANNCASE WESTERN RESERVE UNIVERSITY, OH$120,750DDK
2020Innate Immune Response Following Bacterial Translocation in Early Life1R03DK122187-01A1KNOOP, KATHRYN AMAYO CLINIC ROCHESTER, MN$119,250DDK
2020Enhancing Fatty Acid Oxidation Will Improve Skeletal Muscle & Enable Exercise Adaptation in CKD1R03DK125665-01AVIN, KEITH GINDIANA UNIVERSITY INDIANAPOLIS, IN$118,875DDK
2020Proteostatic regulation of disease-causing polycystin 2 variants1R03DK124659-01 · under PAR-18-103GUERRIERO, CHRISTOPHER JAMESUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$117,375DDK
2020Role of the Gut Microbiome in Reward Network Alterations in Obesity1R03DK121025-01A1 · under PAR-18-103CHURCH, ARPANAUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$117,000DDK
2020The WELL Study (Wellness Education for Liver Health Study): Reducing liver disease in genetically predisposed adults1R03DK124741-01 · under PAR-18-103SASLOW, LAURAUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$117,000DDK
2020Social adversity, gestational stress physiology, and birth outcomes in Hispanic Americans1R03DK125524-01FOX, MOLLY MAURERUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$117,000DDK
2020The Sensing Liver: Localization and Ligands1R03DK123546-01 · under PAR-18-103SHEPARD, BLYTHE DGEORGETOWN UNIVERSITY, DC$116,844DDK
2020Elucidating the effect of the gut microbiota on infant growth and weight gain using germ-free mice1R03DK120992-01A1 · under PAR-18-103TANG, MINGHUAUNIVERSITY OF COLORADO DENVER, CO$116,625DDK
2020Pilot feasibility study of loop diuretics among individuals receiving hemodialysis1R03DK124651-01 · under PAR-18-103FLYTHE, JENNIFER EUNIV OF NORTH CAROLINA CHAPEL HILL, NC$116,625DDK
2020Tissue remodeling in Eosinophilic Esophagitis: Discovery of novel pathways1R03DK125638-01MENARD-KATCHER, CALIES DUNIVERSITY OF COLORADO DENVER, CO$116,625DDK
2020Defining behaviors and the stress response among positive deviants for childhood obesity1R03DK122011-01A1FOSTER, BYRON AOREGON HEALTH & SCIENCE UNIVERSITY, OR$115,500DDK
2020In vivo assessment of granulin dependent myeloid cell formation1R03DK125661-01ESPÍN PALAZÓN, RAQUELIOWA STATE UNIVERSITY, IA$114,750DDK
2020Contribution of host genetic factors to intestinal Coxsackievirus replication1R03DK124749-01 · under PAR-18-103ROBINSON, CHRISTOPHER MICHAELINDIANA UNIVERSITY INDIANAPOLIS, IN$114,635DDK
2020Artificial Intelligence-Based Approaches for Renal Structure Characterization in Computed Tomography Images1R03DK125632-01KLINE, TIMOTHY LEEMAYO CLINIC ROCHESTER, MN$113,350DDK
2020Oncostatin M as a mediator of adipose tissue immune balance1R03DK122121-01A1 · under PAR-18-103ELKS, CARRIE MLSU PENNINGTON BIOMEDICAL RESEARCH CTR, LA$111,000DDK
2020Dietary Oxalate and Innate Immunity in Kidney Stone Disease1R03DK123542-01 · under PAR-18-103MITCHELL, TANECIA RUNIVERSITY OF ALABAMA AT BIRMINGHAM, AL$108,186DDK
2020Missorting of EGFR in cancer pathogenesis1R03DK124713-01 · under PAR-18-103SINGLA, AMIKAUT SOUTHWESTERN MEDICAL CENTER, TX$81,625DDK
2020Renal repair effects of senolytic preconditioned mesenchymal stromal cells in diabetic kidney disease1R03DK123492-01 · under PAR-18-103HICKSON, LATONYA JMAYO CLINIC ROCHESTER, MN$13,675DDK
2020Longitudinal Effects of Diet and the Gut Microbiome on Immunosuppressive Drug Metabolism1R03DK124739-01 · under PAR-18-103MOORE, AIMEE MWASHINGTON UNIVERSITY, MO$6,230DDK
2019The Role of Lysyl Oxidase in Epithelial Differentiation in Eosinophilic Esophagitis1R03DK118310-01A1 · under PAR-18-103MUIR, AMANDA BROOKECHILDREN'S HOSP OF PHILADELPHIA, PA$132,000DDK
2019TEEN HEED: An Adolescent Diabetes Prevention Intervention Incorporating Novel Mobile Health Technologies1R03DK118302-01A1 · under PAR-18-103VANGEEPURAM, NITAICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY$127,125DDK
2019The Role of A20 in Colitis-Associated Cancer1R03DK118178-01A1 · under PAR-18-103SHAO, LINGUNIVERSITY OF SOUTHERN CALIFORNIA, CA$123,750DDK
2019Menin regulates colonic epithelial cell growth through LXR repression1R03DK120946-01 · under PAR-18-103KATONA, BRYSON WILLIAMUNIVERSITY OF PENNSYLVANIA, PA$121,438DDK
2019Determining the Mechanism for ApoC-III Stimulation of IL-10 and Tregs in the Intestine: Is this Novel Effect Beneficial?1R03DK116011-01A1 · under PAR-18-103KOHAN, ALISON BLOOMUNIVERSITY OF CONNECTICUT STORRS, CT$120,469DDK
2019Uncovering the role of LRH-1 in enteroendocrine cell development and ‘gut-brain’ communication1R03DK121061-01 · under PAR-18-103BAYRER, JAMESUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$120,281DDK
2019De-Implementation of Detrimental Feeding Practices in Childcare- Resubmission1R03DK117197-01A1 · under PAR-18-103SWINDLE, TARENUNIV OF ARKANSAS FOR MED SCIS, AR$120,154DDK
2019Dysregulation of Hepatic Energy Metabolism in Argininosuccinate Lyase Deficiency1R03DK119636-01 · under PAR-18-103BURRAGE, LINDSAY CBAYLOR COLLEGE OF MEDICINE, TX$119,719DDK
2019Mechanisms of barrier dysfunction in post-infection irritable bowel syndrome1R03DK120745-01 · under PAR-18-103GROVER, MADHUSUDANMAYO CLINIC ROCHESTER, MN$119,250DDK
2019Mitochondrial injury interferes with endogenous renal repair in experimental renovascular disease1R03DK122137-01 · under PAR-18-103EIRIN, ALFONSOMAYO CLINIC ROCHESTER, MN$119,250DDK
2019Defining the Generation and Cargo of Extracellular Vesicles During the Evolution of Type 1 Diabetes1R03DK117253-01A1 · under PAR-18-103SIMS, EMILY KINDIANA UNIVERSITY INDIANAPOLIS, IN$118,125DDK
2019Pdgfrβ, a mediator of the adipose lineage1R03DK122193-01 · under PAR-18-103BERRY, DANIEL CARLCORNELL UNIVERSITY, NY$117,750DDK
2019Regulation of ENaC expression by paraoxonase-21R03DK119752-01 · under PAR-18-103SHI, SHUJIEUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$117,375DDK
2019Determining the role of Tet1 in intestinal stem cell differentiation and self-renewal1R03DK122111-01 · under PAR-18-103GRACZ, ADAM DAVIDUNIV OF NORTH CAROLINA CHAPEL HILL, NC$116,625DDK
2019Circulating miRNA Signatures of Beta-Cell Response to Metformin or Insulin in Youth with Dysglycemia1R03DK122100-01 · under PAR-18-103JANUSZEWSKI, PANDORA LUKEUNIVERSITY OF WASHINGTON, WA$116,625DDK
2019Early life n-3 fatty acids increase novel Adipogenesis-regulatory cells to condition adipogenesis in a NR2F2 dependent manner1R03DK122189-01 · under PAR-18-103RUDOLPH, MICHAEL C.UNIVERSITY OF COLORADO DENVER, CO$116,625DDK
2019Prevention of hypoglycemia associated autonomic failure by enhancing melanocortin 4 receptor function1R03DK122190-01 · under PAR-18-103CHHABRA, KAVALJIT HUNIVERSITY OF ROCHESTER, NY$115,500DDK
2019Role of gut microbiota in total parenteral nutrition associated injury1R03DK121046-01 · under PAR-18-103JAIN, AJAY K.SAINT LOUIS UNIVERSITY, MO$113,625DDK
2019Renal implications of AQP3 lysine acetylation1R03DK120503-01 · under PAR-18-103HYNDMAN, KELLYUNIVERSITY OF ALABAMA AT BIRMINGHAM, AL$111,375DDK
2019Abnormal cytokine response and autoantigen production in IgA-producing subpopulations in IgA nephropathy1R03DK122194-01 · under PAR-18-103REILY, COLIN ROBERTUNIVERSITY OF ALABAMA AT BIRMINGHAM, AL$111,375DDK
2019The Role of Kidney Immune Cells in Acceleration of Cyst Growth1R03DK119717-01A1 · under PAR-18-103SAIGUSA, TAKAMITSUUNIVERSITY OF ALABAMA AT BIRMINGHAM, AL$111,375DDK
2019Effects of Dietary Phosphorus Restriction on Whole-Body Calcium and Phosphorus Balance and Kinetics in Patients with Moderate Chronic Kidney Disease1R03DK122225-01 · under PAR-18-103GALLANT, KATHLEEN M HILLPURDUE UNIVERSITY, IN$110,574DDK
2019Investigation of Momentary, Prospective Associations Between Working Memory and Eating Behavior in Children1R03DK117198-01A1 · under PAR-18-103GOLDSCHMIDT, ANDREA BETHMIRIAM HOSPITAL, RI$109,500DDK
2019Patient Symptoms on Hemodialysis-Timing, Variability and Causes1R03DK122240-01 · under PAR-18-103MCCAUSLAND, FINNIAN RBRIGHAM AND WOMEN'S HOSPITAL, MA$89,500DDK
2019The Impacts of NR5A2 Pharmacologic Agonism on Pancreas Development and Disease1R03DK122232-01 · under PAR-18-103NISSIM, SAHARBRIGHAM AND WOMEN'S HOSPITAL, MA$89,500DDK
2019Lipidomic Predictors of Diabetic Kidney Disease Progression in Patients with Type-1 Diabetes1R03DK121941-01 · under PAR-18-103AFSHINNIA, FARSADUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$87,861DDK
2019Design Sprint and Usability Testing of a Patient-Facing Diabetes Dashboard Embedded in an Existing Patient Portal Mobile App1R03DK119735-01 · under PAR-18-103MARTINEZ, WILLIAMVANDERBILT UNIVERSITY MEDICAL CENTER, TN$85,000DDK
2019Glucose Homeostasis and Beta Cell Function in Pseudohypoparathyroidism1R03DK119733-01 · under PAR-18-103SHOEMAKER, ASHLEY HALLVANDERBILT UNIVERSITY MEDICAL CENTER, TN$85,000DDK
2019Acot9 Promotes Lipotoxicity1R03DK117247-01A1 · under PAR-18-103ERSOY, BARANWEILL MEDICAL COLL OF CORNELL UNIV, NY$84,750DDK
2019The impact of obesity on cerebral energetics1R03DK121048-01 · under PAR-18-103HWANG, JANICE JINYALE UNIVERSITY, CT$83,750DDK
2019Cytotoxic T cells in Ulcerative Colitis1R03DK121026-01 · under PAR-18-103HAN, ARNOLDCOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$81,000DDK
2019Enterochromaffin cell mechanotransduction and mechanosensitive serotonin release depend on calcium signaling downstream of Piezo2 activation1R03DK119683-01 · under PAR-18-103BEYDER, ARTHURMAYO CLINIC ROCHESTER, MN$79,500DDK
2019Regulation of Liver Metabolism by lncRNAs1R03DK122191-01 · under PAR-18-103TITCHENELL, PAUL MICHAELUNIVERSITY OF PENNSYLVANIA, PA$77,280DDK
2019Role of DPP4-ADA interaction in obesity-induced inflammation1R03DK119680-01 · under PAR-18-103ZHONG, JIXINCASE WESTERN RESERVE UNIVERSITY, OH$77,000DDK
2019Metagenomic and Metabolomic Analysis of the Structure and Function of the Human Gut Microbiome in Congenital Heart1R03DK118303-01A1 · under PAR-18-103TYPPO, KATRI VANAMOUNIVERSITY OF ARIZONA, AZ$76,750DDK
2019Sensory Afferent Mechanisms Contributing to Diabetic Bladder Dysfunction1R03DK119464-01 · under PAR-18-103DEBERRY, JENNIFER JUNIVERSITY OF ALABAMA AT BIRMINGHAM, AL$74,250DDK
2019Rho-associated kinase-dependent cytoskeletal and tight junction dysregulation in necrotizing enterocolitis1R03DK117216-01A1 · under PAR-18-103HUNTER, CATHERINE JANENORTHWESTERN UNIVERSITY AT CHICAGO, IL$49,876ZDK1
2018Identification of Hepatitis B Virus permissiveness factors1R03DK117252-01 · under PAR-16-148SCHWARTZ, ROBERT EWEILL MEDICAL COLL OF CORNELL UNIV, NY$127,125DDK
2018Translational epidemiology methods for whole genome analyses of T2D and glycemia1R03DK118305-01 · under PAR-16-148MANNING, ALISA KNODLEMASSACHUSETTS GENERAL HOSPITAL, MA$126,375DDK
2018Defining the role of MIF and CD74 in autoimmune cholangitis1R03DK117249-01 · under PAR-16-148ASSIS, DAVIDYALE UNIVERSITY, CT$125,625DDK
2018Pharmacokinetic Evaluation to Optimize Infliximab Monotherapy with Personalized Pharmacodynamic Biomarkers1R03DK118314-01 · under PAR-16-148MINAR, PHILLIP PCINCINNATI CHILDRENS HOSP MED CTR, OH$119,250DDK
2018Nonbacterial Gut Microbiome and Fructan Symptom Generation in Childhood IBS1R03DK117219-01 · under PAR-16-148CHUMPITAZI, BRUNO PEDROBAYLOR COLLEGE OF MEDICINE, TX$118,875DDK
2018Autophagy regulation of esophageal basal cell dynamics1R03DK118304-01 · under PAR-16-148WHELAN, KELLY ATEMPLE UNIV OF THE COMMONWEALTH, PA$118,875DDK
2018Mechanisms of IL-6 Signaling in Beta-cell Stress Response1R03DK115990-01A1 · under PAR-16-148LINNEMANN, AMELIA KINDIANA UNIVERSITY INDIANAPOLIS, IN$118,125DDK
2018High-Resolution Plasma Metabolomics for Nutrition-Related Metabolic Assessment in Adults with Cystic Fibrosis1R03DK117246-01 · under PAR-16-148ALVAREZ, JESSICA ALEJANDRAEMORY UNIVERSITY, GA$117,312DDK
2018Control of porphyrin synthesis by CLPX: a novel regulatory node in erythroid heme synthesis1R03DK118307-01 · under PAR-16-148YIEN, YVETTE YUNIVERSITY OF DELAWARE, DE$117,000DDK
2018Daily caloric restriction and intermittent fasting in overweight and obese adults with autosomal dominant polycystic kidney disease1R03DK118215-01 · under PAR-16-148NOWAK, KRISTEN LYNNUNIVERSITY OF COLORADO DENVER, CO$116,625DDK
2018An Il-6/Stat3 autocrine axis in adipose tissue1R03DK118195-01 · under PAR-16-148REILLY, SHANNON MARIEUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$116,250DDK
2018Role of p53 in Kidney Development: Modeling Renal Anomalies of Li-Fraumeni Patients1R03DK118771-01 · under PAR-16-148MILLER, RACHEL KATHERINEUNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON, TX$115,500DDK
2018Role of placental nutrient-sensor protein mTOR on fetal programming of beta-cell dysfunction and susceptibility to type 2 diabetes1R03DK114465-01A1 · under PAR-16-148ALEJANDRO, EMILYNUNIVERSITY OF MINNESOTA, MN$115,313DDK
2018Investigating the Utility of Nanobodies for Glomerular Disease Treatment1R03DK118315-01 · under PAR-16-148KERLIN, BRYCE ANDREWRESEARCH INST NATIONWIDE CHILDREN'S HOSP, OH$114,000DDK
2018Roles and Regulation of Ribonuclease 6 in Defending the Urinary Tract Against Bacterial Infection1R03DK118306-01 · under PAR-16-148BECKNELL, BRIANRESEARCH INST NATIONWIDE CHILDREN'S HOSP, OH$114,000DDK
2018Examination of the Feasibility and Preliminary Efficacy of Yoga as an Intervention Approach to Improving Long-Term Weight Loss1R03DK115978-01A1 · under PAR-16-148UNICK, JESSICA LMIRIAM HOSPITAL, RI$109,500DDK
2018Characterization and novel imaging of skeletal muscle fibrosis in patients with chronic kidney disease1R03DK116023-01 · under PAR-16-148ABRAMOWITZ, MATTHEW KALBERT EINSTEIN COLLEGE OF MEDICINE, INC, NY$91,939DDK
2018Mechanisms of Dyslipidemia following Preeclampsia1R03DK115793-01 · under PAR-16-148KHANKIN, ELIYAHUBETH ISRAEL DEACONESS MEDICAL CENTER, MA$87,500DDK
2018Impact of insufficient sleep on peripheral metabolic tissues1R03DK118309-01 · under PAR-16-148BROUSSARD, JOSIANECOLORADO STATE UNIVERSITY, CO$85,178DDK
2018Investigating microbial regulation of intestinal mononuclear phagocyte production of TL1A in ILC3-dependent barrier immunity1R03DK111852-01A1 · under PAR-16-148LONGMAN, RANDY SWEILL MEDICAL COLL OF CORNELL UNIV, NY$84,750DDK
2018Epicutaneous Tolerance Induction with Flagellin Epitopes for the Treatment of Colitis1R03DK117218-01 · under PAR-16-148DUNKIN, DAVIDICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY$84,750DDK
2018Anti-TNF therapy in ulcerative colitis: a comprehensive study of health-care utilizations and societal cost1R03DK113337-01A1 · under PAR-16-148KHALILI, HAMEDMASSACHUSETTS GENERAL HOSPITAL, MA$84,250DDK
2018Mechanisms of DRG Stimulation to Modulate Visceral Afferent Function1R03DK114546-01A1 · under PAR-16-148FENG, BINUNIVERSITY OF CONNECTICUT STORRS, CT$79,750DDK
2018Epigenetic Regulation in Primary Sclerosing Cholangitis1R03DK113339-01A1 · under PAR-16-148HUEBERT, ROBERT CHRISTIANMAYO CLINIC ROCHESTER, MN$79,500DDK
2018Circadian Control of Nutrient-Sensing Pathways Through Clock-HIF Interactions in Skeletal Muscle1R03DK116012-01 · under PAR-16-148PEEK, CLARA BIENNORTHWESTERN UNIVERSITY AT CHICAGO, IL$79,000DDK
2018Mechanisms of Salmonella Clearance by Neutrophils in the Intestinal Lumen1R03DK116663-01 · under PAR-16-148SUMAGIN, RONENNORTHWESTERN UNIVERSITY AT CHICAGO, IL$79,000DDK
2018Peripheral Arterial Disease in Older Patients with Chronic Kidney Disease1R03DK113341-01A1 · under PAR-16-148CHANG, TARA I-HSINSTANFORD UNIVERSITY, CA$78,500ZDK1
2018PGC1a Downregulation Contributes to the Pathogenesis of Inflammatory Bowel Disease1R03DK114464-01A1 · under PAR-16-148MOLLEN, KEVIN PUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$78,126DDK
2018Epithelial A2B-mediated Muc5ac expression protects the intestinal barrier during inflammation.1R03DK114545-01A1 · under PAR-16-148AHERNE, CAROLUNIVERSITY OF COLORADO DENVER, CO$77,750DDK
2018Mitochondrial bioenergetics in persons with chronic kidney disease1R03DK114502-01A1 · under PAR-16-148ROSHANRAVAN, BABACKUNIVERSITY OF WASHINGTON, WA$4,878ZDK1
2017Mitochondrial creatine metabolism and glucose utilization in humans.1R03DK114491-01 · under PAR-16-148MCCORMACK, SHANA ERINCHILDREN'S HOSP OF PHILADELPHIA, PA$86,000DDK
2017Genetic predictors of calprotectin response with anti-TNF and anti-integrin therapy in inflammatory bowel diseases1R03DK112909-01 · under PAR-16-148ANANTHAKRISHNAN, ASHWIN NMASSACHUSETTS GENERAL HOSPITAL, MA$85,500DDK
2017Prospective Functional Characterization of All Possible Missense Variants in HNF1A1R03DK113328-01 · under PAR-16-148MAJITHIA, AMITMASSACHUSETTS GENERAL HOSPITAL, MA$85,500DDK
2017Metabolite profiling for Coronary Artery Disease in Nonalcoholic Fatty Liver Disease1R03DK113349-01 · under PAR-16-148COREY, KATHLEEN ELIZABETHMASSACHUSETTS GENERAL HOSPITAL, MA$85,500DDK
2017Regulation of Pancreatic Islet Homeostasis by the Adipsin Pathway1R03DK111762-01 · under PAR-15-343LO, JAMES CWEILL MEDICAL COLL OF CORNELL UNIV, NY$84,750DDK
2017Promotora Intervention for Metabolic and MentalHealth (PRIME2)1R03DK109243-01A1 · under PAR-15-343O'BRIEN, MATTHEW JAMESNORTHWESTERN UNIVERSITY AT CHICAGO, IL$82,371DDK
2017Contribution of bone to FGF23 Elevation in kidney disease1R03DK111855-01 · under PAR-15-343CHRISTOV, MARTANEW YORK MEDICAL COLLEGE, NY$82,000DDK
2017Renal Regulation of the Magnesium Channel TRPM6 by Uromodulin1R03DK111776-01 · under PAR-15-343WOLF, MATTHIAS TILMANN FLORIANUT SOUTHWESTERN MEDICAL CENTER, TX$81,000DDK
2017New model to dissect molecular pathways in IBD-neoplasia using human colonoids1R03DK109218-01A1 · under PAR-15-343PEKOW, JOELUNIVERSITY OF CHICAGO, IL$80,688DDK
2017Cellular targets of acute and chronic strains of MNV1R03DK110397-01A1 · under PAR-16-148TOMOV, VESSELINUNIVERSITY OF PENNSYLVANIA, PA$80,500DDK
2017Enteroendocrine Cell Subsets with Reserve Stem Cell Function1R03DK114656-01 · under PAR-16-148YAN, KELLEYCOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$80,000DDK
2017Impact of Sex and Diet on Mesolimbic Amylin Signaling for Energy Balance Control1R03DK114211-01 · under PAR-16-148MIETLICKI-BAASE, ELIZABETH GENEVIEVESTATE UNIVERSITY OF NEW YORK AT BUFFALO, NY$79,750DDK
2017Mechanisms of alteration of gastrointestinal physiology by gut microbes1R03DK111850-01 · under PAR-15-343KASHYAP, PURNA CMAYO CLINIC ROCHESTER, MN$79,500DDK
2017Identifying and addressing disparities in patient-centered diabetes care1R03DK109107-01A1 · under PAR-15-343PHELAN, SEAN MMAYO CLINIC ROCHESTER, MN$79,500DDK
2017Evaluating and Improving Cardiac Arrest Resuscitation Efforts in Hemodialysis Clinics1R03DK113324-01 · under PAR-16-148PUN, PATRICK HDUKE UNIVERSITY, NC$79,500DDK
2017Tasting gut bacteria1R03DK114500-01 · under PAR-16-148BOHORQUEZ, DIEGO VDUKE UNIVERSITY, NC$79,500DDK

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