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NIH funding notice PAR-20-117

Maximizing Investigators Research Award (MIRA) for Early Stage Investigators (R35 - Clinical Trial Optional)

Closed on October 3, 2022.

Posted
February 24, 2020
Close date
October 3, 2022
Activity codes
Not stated on the notice page
Institutes taking part
Not stated on the notice page

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

Its page was not saved, so the notices it replaced are not known.

Who won it before

782 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $294,123,071 in first-year total cost, median $383,481.

Most frequent study sections

  1. Maximizing Investigators' Research Award C Study Section[MRAC]53
  2. Maximizing Investigators’ Research Award B Study Section[MRAB]51
  3. Maximizing Investigators? Research Award A Study Section[MRAA]45
  4. Special Emphasis Panel[ZRG1 GGG-S (55)]36
  5. Special Emphasis Panel[ZRG1 CB-V (55)]33

Most frequent institutions

  1. UNIVERSITY OF CHICAGO17
  2. YALE UNIVERSITY16
  3. UNIVERSITY OF FLORIDA15
  4. UNIVERSITY OF UTAH14
  5. OHIO STATE UNIVERSITY13
Competing awards under PAR-20-117 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2023Hybrid Model-Based and Data-Driven Frameworks for High-Resolution Tomographic Imaging1R35GM150982-01PANDE, KANUPRIYAUNIVERSITY OF CALIF-LAWRENC BERKELEY LAB, CA$505,225ZRG1
2023Elucidating the molecular and cellular functions of polyamines1R35GM151111-01JAIN, ANKURWHITEHEAD INSTITUTE FOR BIOMEDICAL RES, MA$487,500ZRG1
2023Understanding the OAS/RNase L pathway during pathogenic viral infections1R35GM151249-01BURKE, JAMES MUNIVERSITY OF FLORIDA, FL$483,000ZRG1
2023Photoproximity labeling as a tool for epigenetic drug discovery1R35GM150765-01SEATH, CIARANUNIVERSITY OF FLORIDA, FL$483,000MRAB
2023Regulation of mitochondrial fatty acid synthesis in the control of mitochondrial metabolism.1R35GM151245-01NOWINSKI, SARA MARIEVAN ANDEL RESEARCH INSTITUTE, MI$475,000MRAD
2023Single-cell transcriptomics of complex bacterial communities1R35GM150994-01KUCHINA, ANNAINSTITUTE FOR SYSTEMS BIOLOGY, WA$470,000ZRG1
2023Telomerase RNP Prisonbreaks from Phase-Separated Nuclear Body1R35GM150538-01CHEN, LURESEARCH INST OF FOX CHASE CAN CTR, PA$470,000MRAC
2023Innate lymphocyte responses to early-life infections1R35GM151347-01CONSTANTINIDES, MICHAEL GEORGESCRIPPS RESEARCH INSTITUTE, THE, CA$452,500ZRG1
2023Biochemical and Physiological Phenotypes of CV Dysfunction In Human Cell Models1R35GM151098-01GANETZKY, REBECCACHILDREN'S HOSP OF PHILADELPHIA, PA$445,000ZRG1
2023Developing C. elegans as a model to understand tRNA-fragment biogenesis and function1R35GM151087-01CONINE, COLINCHILDREN'S HOSP OF PHILADELPHIA, PA$445,000ZRG1
2023Mechanisms and functions of cell surface glycoRNAs1R35GM151157-01FLYNN, RYAN ALEXANDERBOSTON CHILDREN'S HOSPITAL, MA$442,500ZRG1
2023Understanding Immune-Stromal Interactions in Tissue Homeostasis and Inflammation1R35GM151000-01ZHOU, XUBOSTON CHILDREN'S HOSPITAL, MA$442,500ZRG1
2023Unveiling Functional Roles of Apical Surface Interactions Between Opposing Cell Layers1R35GM149516-01FU, HONGXIAUNIVERSITY OF WASHINGTON, WA$441,250ZRG1
2023Mechanistic Characterization of the Replication Stress Response1R35GM150532-01ADEYEMI, RICHARDFRED HUTCHINSON CANCER CENTER, WA$440,000ZRG1
2023High-throughput discovery of disease-associated ion channel variants1R35GM150465-01GLAZER, ANDREW M.VANDERBILT UNIVERSITY MEDICAL CENTER, TN$437,500ZRG1
2023Development of Chemical Platforms for Acoustically Controlled Molecular Delivery1R35GM150988-01ROBB, MAXWELL JCALIFORNIA INSTITUTE OF TECHNOLOGY, CA$425,000ZRG1
2023Macrophage-mediated regulation of inflammation and tissue repair1R35GM150816-01FRANKLIN, RUTH AHARVARD MEDICAL SCHOOL, MA$423,750MRAD
2023Molecular mechanisms underlying T cell resistance to PD-1 signaling1R35GM150989-01TOCHEVA, ANNA SICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY$422,500ZRG1
2023Structural systems biology of microenvironmental oxidative stress and synthetic biology intervention1R35GM151236-01CHANG, ROGER LARKENALBERT EINSTEIN COLLEGE OF MEDICINE, NY$420,000ZRG1
2023Determinants of epigenetic inheritance in human stem cell fate decisions1R35GM151179-01ESCOBAR, THELMAUNIVERSITY OF WASHINGTON, WA$419,039ZRG1
2023Discovery and characterization of bacterial cell envelope assembly and remodeling networks that modulate tolerance to antibiotics1R35GM150669-01FLORES-KIM, JOSUEUNIV OF MASSACHUSETTS MED SCH WORCESTER, MA$418,750ZRG1
2023The Evolution of Genomic Imprinting and Strong Reproductive Isolation1R35GM150907-01COUGHLAN, JENNIFER M.YALE UNIVERSITY, CT$418,750ZRG1
2023Elucidating how ATR promotes genome stability independent of the DNA damage response pathway1R35GM150648-01KABECHE, LILIAN CAROLINAYALE UNIVERSITY, CT$418,750MRAC
2023Mechanics of mammalian morphogenesis1R35GM150645-01SUMIGRAY, KAELYN D.YALE UNIVERSITY, CT$418,750MRAC
2023Protein Structural Dynamics in Living Cells1R35GM151146-01DAVIS, CAITLINYALE UNIVERSITY, CT$418,750MRAB
2023A systems approach to decode mitochondrial metabolite transport1R35GM150619-01SHEN, HONGYINGYALE UNIVERSITY, CT$418,750MRAB
2023Understanding double-stranded RNA recognition in human cells1R35GM150953-01FANG, WENWENUNIV OF MASSACHUSETTS MED SCH WORCESTER, MA$418,750ZRG1
2023Integration of Immunologic Phenotyping with Computational Approaches to Predict Clinical Trajectory in Septic Patients1R35GM150695-01BONAVIA, ANTHONY SPENNSYLVANIA STATE UNIV HERSHEY MED CTR, PA$418,500MRAD
2023Bioorthogonal temporospatial tools1R35GM150508-01CARLSON, JONATHANMASSACHUSETTS GENERAL HOSPITAL, MA$417,500ZRG1
2023Identifying regulatory networks that govern primary cilia remodeling and neural signaling1R35GM151229-01LOUKIL, ABDELHALIMSANFORD RESEARCH/USD, SD$415,000ZRG1
2023The molecular determinants of surface-templated self-association of intrinsically disordered proteins1R35GM150716-01CHUNG, PETER JUNIVERSITY OF SOUTHERN CALIFORNIA, CA$413,864MRAB
2023Innate and Hormone-Mediated Sex Differences in Extracellular Matrix Remodeling1R35GM151127-01CONNIZZO, BRIANNE KATHRYNBOSTON UNIVERSITY (CHARLES RIVER CAMPUS), MA$412,500ZRG1
2023Intra- and inter-cluster regulations of multiplex gene clusters1R35GM150714-01LIANG, YA-CHENUNIVERSITY OF SOUTHERN CALIFORNIA, CA$412,500ZRG1
2023Cadherin regulation of planar polarity1R35GM150921-01STAHLEY, SARA NPENNSYLVANIA STATE UNIV HERSHEY MED CTR, PA$411,924MRAC
2023Role of long non-coding RNAs in exosome biogenesis1R35GM151259-01MOMEN HERAVI, FATEMEHCOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$411,250ZRG1
2023Understanding the antiviral roles of acellular RNA quality control pathway1R35GM150778-01STECKELBERG, ANNA-LENACOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$411,250ZRG1
2023Machine learning of biomolecular interactions and the human signaling networks they comprise1R35GM150546-01ALQURAISHI, MOHAMMED NAZARCOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$411,250MRAB
2023Discovering interpretable mechanisms explaining high dimensional biomolecular data1R35GM150897-01LIN, MILOUT SOUTHWESTERN MEDICAL CENTER, TX$410,000ZRG1
2023Genetic mapping of the inflammatory adaption circuit in epithelial stem cells1R35GM150610-01MIAO, YUXUAN PHOENIXUNIVERSITY OF CHICAGO, IL$410,000MRAC
2023Trans-Golgi Network Remodeling by Microbial Factors1R35GM151390-01CHEN, JUEQIUNIVERSITY OF CHICAGO, IL$410,000ZRG1
2023Methods for leveraging family-based designs and summary data to elucidate complex trait genetics1R35GM150836-01RAY, DEBASHREEJOHNS HOPKINS UNIVERSITY, MD$409,375ZRG1
2023Anastasis: A Novel Cell Survival Mechanism1R35GM150835-01TANG, HO LAMJOHNS HOPKINS UNIVERSITY, MD$409,375MRAC
2023Bacterial and Viral Predator-Prey Dynamics within Bacterial Biofilms at Cellular Resolution1R35GM151158-01NADELL, CAREYDARTMOUTH COLLEGE, NH$409,171ZRG1
2023Investigating neofunctionalized alpha-carbonic anhydrases as an emerging class of biosynthetic enzyme in plant and animal metabolism1R35GM150908-01NETT, RYAN STEPHANHARVARD UNIVERSITY, MA$408,981MRAB
2023The coordination of cell size control and cell cycle regulation at developmental extremes1R35GM150853-01AMODEO, AMANDA ADARTMOUTH COLLEGE, NH$408,958MRAC
2023Anesthesia and Sleep: Mechanisms of Generating Two Similar Yet Distinct Unconscious States in the Medulla1R35GM151166-01IMAMURA, TOSHIHIROUNIVERSITY OF PENNSYLVANIA, PA$406,250MRAD
2023Cellular and circuit mechanisms of the therapeutic action of inhaled nitrous oxide in rodent models of chronic stress1R35GM151160-01CICHON, JOSEPHUNIVERSITY OF PENNSYLVANIA, PA$406,250ZRG1
2023Methods for inferring and analyzing gene regulatory networks using single-cell multiomics and spatial genomics data1R35GM150887-01HOU, WENPINCOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$406,218ZRG1
2023Photothermal Catalysis: Using light to thermally generate reactive intermediates with temporal and spatial control1R35GM150839-01STACHE, ERINPRINCETON UNIVERSITY, NJ$405,833ZRG1
2023Molecular regulation of the CRAC channel signaling pathway1R35GM151170-01HOU, XIAOWEIUNIVERSITY OF CINCINNATI, OH$405,000ZRG1
2023Next-Generation Algorithms in Statistical Genetics Based on Modern Machine Learning1R35GM151243-01KULESHOV, VOLODYMYRCORNELL UNIVERSITY, NY$404,753ZRG1
2023Computational Methods for Emerging Spatially-resolved Transcriptomics with Multiple Samples1R35GM150671-01HICKS, STEPHANIE CARINNEJOHNS HOPKINS UNIVERSITY, MD$404,485MRAA
2023Integrated frameworks for single-cell epigenomics based transcriptional regulatory networks1R35GM150616-01UZUN, YASINPENNSYLVANIA STATE UNIV HERSHEY MED CTR, PA$404,214ZRG1
2023The Platelet Transcriptome and Organ Failure After Injury: Discovering Molecular Biomarkers and Preventative Targets through Interrogating Novel RNA Modifications1R35GM150656-01KORNBLITH, LUCY ZUMWINKLEUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$403,750MRAD
2023Decoding cortical Notch signaling and morphogenic instruction at cell-cell interfaces1R35GM150987-01KUTYS, MATTHEW LUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$403,750ZRG1
2023Using in vivo genetic and physical interaction data for structure determination of protein assemblies1R35GM151256-01ECHEVERRIA RIESCO, IGNACIAUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$403,750ZRG1
2023Mechanisms of RNA turnover during the epithelial-mesenchymal transition1R35GM150763-01HUTCHINS, ERICAUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$403,750MRAC
2023Landscapes for Cell State Transition Leveraging by Single-Cell Multi-Omics1R35GM150460-01WANG, GUANGYUMETHODIST HOSPITAL RESEARCH INSTITUTE, TX$403,739MRAA
2023Arginyl-tRNA beyond translation: mechanism and regulation of protein arginylation1R35GM150678-01ZHANG, YICASE WESTERN RESERVE UNIVERSITY, OH$402,500MRAB
2023Deciphering enhancer regulation in stem cells1R35GM150668-01CAO, KAIXIANGCASE WESTERN RESERVE UNIVERSITY, OH$402,500MRAC
2023Molecular basis of plasma membrane rupture in lytic cell death and its inhibition by cytoprotective agent glycine1R35GM151043-01DAI, XINGHONGCASE WESTERN RESERVE UNIVERSITY, OH$402,500MRAB
2023Novel statistical genetics methods to unravel polygenic interactions in complex traits1R35GM150822-01DAHL, ANDREWUNIVERSITY OF CHICAGO, IL$401,296MRAA
2023Probing the role of sensory cues in the regulation of bacterial biofilm development1R35GM150803-01MUKHERJEE, SAMPRITIUNIVERSITY OF CHICAGO, IL$401,296MRAA
2023Mechanisms regulating the biosynthesis and signaling of oxylipins1R35GM150691-01TOURDOT, BENJAMIN ERICCINCINNATI CHILDRENS HOSP MED CTR, OH$401,250ZRG1
2023Evolutionary genetics of adaptation to toxins in animals1R35GM150574-01TARVIN, REBECCA D.UNIVERSITY OF CALIFORNIA BERKELEY, CA$401,250ZRG1
2023Nanoelectronics to study exosome circuitry and their role in neuroregeneration1R35GM150860-01ESFANDIARI, LEYLAUNIVERSITY OF CINCINNATI, OH$401,247ZRG1
2023Molecular Chaperone-mediated Regulation of Cell Metabolism1R35GM150481-01PEDLEY, ANTHONY MPENNSYLVANIA STATE UNIVERSITY, THE, PA$401,000ZRG1
2023Factors and Functions of Contact Sites between Membrane-bound and Membrane-less Organelles1R35GM151054-01LEE, JASON EDWARDBAYLOR COLLEGE OF MEDICINE, TX$400,000ZRG1
2023Dissecting the Mechanisms of Quaking-Regulated RNA Processing1R35GM151324-01FAGG, WILLIAM SAMUELUNIVERSITY OF TEXAS MED BR GALVESTON, TX$400,000ZRG1
2023Modeling the mucosal glycopeptide mesh for improved disease understanding and mucin-inspired biomaterial design1R35GM151231-01CHAKRABORTY, SRIRUPANORTHEASTERN UNIVERSITY, MA$398,958ZRG1
2023Plant terpenoids: Deciphering metabolic pathways and improving production in microbes1R35GM150552-01WANG, ZHENSTATE UNIVERSITY OF NEW YORK AT BUFFALO, NY$398,828ZRG1
2023Investigating the involvement of small intestine in metformin's effect on hepatic lipid metabolism1R35GM150985-01LIU, XIAOJINGNORTH CAROLINA STATE UNIVERSITY RALEIGH, NC$397,608ZRG1
2023Mechanisms of cyclical degeneration and regeneration in an avian model system1R35GM150562-01LARSON, TRACY ALISONUNIVERSITY OF VIRGINIA, VA$397,501MRAC
2023Lysosomal quality control through lipid remodeling1R35GM150506-01TAN, XIAOJUNUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$397,500MRAC
2023Neuroimmune signaling in surgical wound healing and modulation by regional anesthesia1R35GM150680-01RITTER JONES, MARSHA ELIZABETHUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$397,500MRAD
2023Leveraging phylogenetic approaches to investigate the evolution of gene expression1R35GM151348-01PENNELL, MATTHEW WESLEYUNIVERSITY OF SOUTHERN CALIFORNIA, CA$397,469ZRG1
2023Structural Basis and Molecular Mechanism of GPCR-Arrestin Interactions1R35GM151033-01CHEN, QIUYANINDIANA UNIVERSITY INDIANAPOLIS, IN$396,250MRAB
2023Making Genomic Prediction of Complex Disease Equitable1R35GM151108-01HARPAK, ARBELUNIVERSITY OF TEXAS AT AUSTIN, TX$396,250ZRG1
2023Polarity mechanisms driving complex morphogenesis1R35GM150466-01MUROYAMA, ANDREW DUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$395,000MRAC
2023Elucidating the role of the Integrated Stress Response pathway in tissue homeostasis1R35GM150516-01VASUDEVAN, DEEPIKAUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$394,727MRAC
2023Spatially resolved multiomics profiling of microbes and their host tissue1R35GM150838-01LIU, YANGYALE UNIVERSITY, CT$394,450ZRG1
2023RIG-I-like receptor regulation of pulmonary inflammation and homeostasis1R35GM150503-01HEMANN, EMILY ANNOHIO STATE UNIVERSITY, OH$393,750MRAC
2023Chemoenzymatic Protein Semisynthesis Approaches Toward Cell Signaling Enzymes1R35GM151124-01CHU, NAM KYOHIO STATE UNIVERSITY, OH$393,750ZRG1
2023Identification of novel type III IFN regulatory pathways1R35GM150806-01FORERO, ADRIANAOHIO STATE UNIVERSITY, OH$393,750ZRG1
2023Analyzing the long-term effects of DNA methylation meditated immunosuppression following sepsis1R35GM150968-01WISLER, JON ROHIO STATE UNIVERSITY, OH$393,750MRAD
2023Investigating the functional impact of genetic variants in the human proteome1R35GM150723-01SEARLE, BRIAN CHIH-SENGOHIO STATE UNIVERSITY, OH$393,750MRAA
2023Engineering Tissue Level Targeting of Biologic Drugs via Automated Interfacial Microneedle Pumps1R35GM150689-01ABRAMSON, ALEXGEORGIA INSTITUTE OF TECHNOLOGY, GA$393,500ZRG1
2023Multiscale approaches to engineering living cells for nanotherapeutic delivery1R35GM150507-01ZHAO, ZONGMINUNIVERSITY OF ILLINOIS AT CHICAGO, IL$393,371MRAB
2023Integrative biophysical modeling for collective tissue mechanics1R35GM150494-01BI, DAPENGNORTHEASTERN UNIVERSITY, MA$393,000MRAC
2023Population genetic modeling of genetic variation for complex traits and diseases1R35GM151257-01BERG, JEREMY JACKSONUNIVERSITY OF CHICAGO, IL$392,592ZRG1
2023Intrinsically Disordered Protein Structural Dynamics from Combined Solution and Gas-Phase Approaches1R35GM151251-01WEBB, IANINDIANA UNIVERSITY INDIANAPOLIS, IN$392,553ZRG1
2023A Fullerene-based Molecular Route towards Designer Nanoparticles1R35GM151131-01ZHANG, JIANYUANRUTGERS, THE STATE UNIV OF N.J., NJ$392,500ZRG1
2023Structure and mechanism of membrane enzymes responsible for bacterial lipid modification and polymyxin resistance1R35GM150831-01PETROU, VASILEIOS IRUTGERS BIOMEDICAL AND HEALTH SCIENCES, NJ$392,500MRAB
2023Characterizing the full spectrum of genomic variation in biomedically-relevant primates1R35GM151008-01PFEIFER, SUSANNE PARIZONA STATE UNIVERSITY-TEMPE CAMPUS, AZ$392,500ZRG1
2023Development of data driven and AI empowered systems biology to study human diseases1R35GM150971-01ZHANG, CHIINDIANA UNIVERSITY INDIANAPOLIS, IN$392,323ZRG1
2023Macrophage-Fibroblast Communication in Cell Migration and Extracellular Matrix Remodeling1R35GM150815-01ZERVANTONAKIS, IOANNISUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$391,600MRAC
2023Osmotic Regulation of a Peptide Ligand-Mediated Signaling1R35GM151096-01QI, XINGYUNRUTGERS THE STATE UNIV OF NJ CAMDEN, NJ$391,408ZRG1
2023Mitochondrial inorganic polyphosphate in the mammalian stress response.1R35GM150799-01SOLESIO TORREGROSA, MARIA DE LA ENCARNACIONRUTGERS THE STATE UNIV OF NJ CAMDEN, NJ$391,408ZRG1
2023Chemical Proteomics Approach to Discover Novel Small Molecule E3 Ligase recruiters for Targeted Protein degradation (TPD)1R35GM150920-01CHANG, JAEWONEMORY UNIVERSITY, GA$391,250MRAB
2023Establishing an immune mechanome1R35GM151041-01DATTA, MEENALUNIVERSITY OF NOTRE DAME, IN$391,250ZRG1
2023INVESTIGATE SEQUENCE SPECIFICITY IN THE BIOSYNTHESIS AND RECOGNITION OF RNA CHEMICAL MODIFICATIONS1R35GM150789-01ZHOU, HUIQINGBOSTON COLLEGE, MA$391,250ZRG1
2023Cell death proteins as inflammatory mediators in sepsis1R35GM151220-01LYONS, JOHN DANIELEMORY UNIVERSITY, GA$391,250MRAD
2023Ins and Outs of Abscission Checkpoint Signaling: Molecular Mechanisms Safeguarding Abscission1R35GM150519-01WENZEL, DAWNMEDICAL COLLEGE OF WISCONSIN, WI$390,000MRAC
2023Elucidating the Mechanisms of Immune Dysfunction After Severe Burn Injury1R35GM151165-01THAKKAR, RAJANRESEARCH INST NATIONWIDE CHILDREN'S HOSP, OH$390,000MRAD
2023Increasing the Complexity of Microtubule-based transport: Cargo adaptors and Hitchhiking on Vesicles.1R35GM150857-01SALOGIANNIS, JOHNUNIVERSITY OF VERMONT & ST AGRIC COLLEGE, VT$390,000MRAD
2023Elucidating the roles for discrete actin filaments in maintenance of organelle and cellular homeostasis1R35GM150811-01CHAKRABARTI, RAJARSHITHOMAS JEFFERSON UNIVERSITY, PA$390,000ZRG1
2023Real-time structural and functional studies of SARS-CoV-2 spike proteins1R35GM150528-01LIN, YI-CHIHUNIVERSITY OF TEXAS AT AUSTIN, TX$389,820ZRG1
2023Single cell quantification of translation control in early mouse development1R35GM150667-01CENIK, CANUNIVERSITY OF TEXAS AT AUSTIN, TX$389,230MRAC
2023Technology for evaluating drug-binding responses to small-molecule perturbation1R35GM150919-01SCHWEPPE, DEVIN KARLUNIVERSITY OF WASHINGTON, WA$388,750ZRG1
2023Dissecting intracellular metabolite trafficking using chemoproteomics1R35GM150899-01GALMOZZI, ANDREAUNIVERSITY OF WISCONSIN-MADISON, WI$388,750ZRG1
2023Elucidating factors that modulate mammalian DNA repair to improve genome editing1R35GM150462-01HESS, GAELEN TUNIVERSITY OF WISCONSIN-MADISON, WI$388,750ZRG1
2023Delineating phosphorylation-mediated regulation of mitochondrial function1R35GM151130-01NIEMI, NATALIEWASHINGTON UNIVERSITY, MO$388,750MRAD
2023Investigating the Molecular Basis of Transposon Regulation and Function in Animal Development1R35GM151016-01NINOVA, MARIA ANTONINOVAUNIVERSITY OF CALIFORNIA RIVERSIDE, CA$388,750ZRG1
2023Investigating the Regulatory Roles of Histone Chaperones in Cellular Plasticity1R35GM151004-01CHELOUFI, SIHEMUNIVERSITY OF CALIFORNIA RIVERSIDE, CA$388,750ZRG1
2023From cells to communities: The multi-scale impacts of bacteriophages in the gut microbiome1R35GM150996-01HRYCKOWIAN, ANDREW JOHNUNIVERSITY OF WISCONSIN-MADISON, WI$388,750ZRG1
2023Molecular mechanisms of endocytic initiation and cargo selection1R35GM150960-01BAKER, RICHARD WAYNEUNIV OF NORTH CAROLINA CHAPEL HILL, NC$388,750ZRG1
2023Chromosome evolution and rapid Y chromosome degeneration1R35GM151123-01BRACEWELL, RYANTRUSTEES OF INDIANA UNIVERSITY, IN$388,319MRAA
2023Regulation of tissue stem cell lineages by nuclear receptor signaling1R35GM150517-01WEAVER, LESLEY NICOLETRUSTEES OF INDIANA UNIVERSITY, IN$388,226MRAC
2023Fundamental Mechanisms of Higher-Order Circadian Rhythms1R35GM150618-01KORONOWSKI, KEVIN BUNIVERSITY OF TEXAS HLTH SCIENCE CENTER, TX$387,500MRAD
2023Phylogenomic mechanisms of trait evolution and resilience to disease1R35GM150590-01DAANE, JACOB MICHAELUNIVERSITY OF HOUSTON, TX$387,500MRAA
2023Examination of sex hormone alteration on post-operative pain development and treatment1R35GM150979-01WILKERSON, JENNYTEXAS TECH UNIVERSITY HEALTH SCIS CENTER, TX$387,500MRAD
2023Dynamic regulatory impact of human transposable elements on gene expression1R35GM150459-01WARD, MICHELLE CLAIREUNIVERSITY OF TEXAS MED BR GALVESTON, TX$387,465ZRG1
2023Control of Klebsiella capsule biosynthesis and attachment1R35GM150588-01MIKE, LAURA ANZALDIUNIVERSITY OF TOLEDO HEALTH SCI CAMPUS, OH$386,250ZRG1
2023Role of novel histone modifications and variants in transcriptional regulation1R35GM150587-01SPANGLE, JENNIFER MARIEEMORY UNIVERSITY, GA$385,755ZRG1
2023Programmable DNA Nanostructures as Biomedical and Structural Scaffolds1R35GM150672-01CHANDRASEKARAN, ARUN RICHARDSTATE UNIVERSITY OF NEW YORK AT ALBANY, NY$385,600MRAB
2023Room Temperature Protein Conformational Dynamics at Microsecond Timescales1R35GM151218-01SRIVASTAVA, MADHURCORNELL UNIVERSITY, NY$385,443ZRG1
2023Revealing mechanisms of specificity and adaptability in molecular information processing through data-driven models1R35GM151211-01MURUGAN, ARVINDUNIVERSITY OF CHICAGO, IL$385,136ZRG1
2023Determinants underlying horizontal gene transfer-mediated pathogen success1R35GM150871-01LOPATKIN, ALLISONUNIVERSITY OF ROCHESTER, NY$385,000MRAA
2023Mechanistic Insights into Catalytic Acyl C-O and C-N Activation and Cross Coupling1R35GM150833-01KENNEDY, ROSEUNIVERSITY OF ROCHESTER, NY$385,000ZRG1
2023Profiles and impact of venous congestion on organ function and patient outcomes in sepsis1R35GM151107-01EHRMAN, ROBERT RUSSELLWAYNE STATE UNIVERSITY, MI$385,000MRAD
2023Mechanisms of polarized protein sorting in AP-1B-deficient epithelia1R35GM150570-01CACERES, PAULO SEBASTIANWAYNE STATE UNIVERSITY, MI$385,000ZRG1
2023Integrated mass spectrometry-based chemoproteomic and genomic technologies for studying dynamic kinase interactomes1R35GM150766-01GOLKOWSKI, MARTINUNIVERSITY OF UTAH, UT$385,000ZRG1
2023Basis and Function of Lateral Assembly of Cadherin Molecules in Adhesive Junctions of Humans and Model Organisms1R35GM150961-01BRASCH, JULIAUNIVERSITY OF UTAH, UT$385,000ZRG1
2023Identifying limitations on microbial host jumps1R35GM150722-01KARASOV, TALIAUNIVERSITY OF UTAH, UT$385,000ZRG1
2023Chromatin and metabolic regulation of plasticity in a predatory nematode1R35GM150720-01WERNER, MICHAEL SUNIVERSITY OF UTAH, UT$385,000ZRG1
2023Mapping the Cellular Responses to DNA Double-Strand Breaks Using On-Demand CRISPR technologies and High-resolution Fluorescence Microscopy1R35GM150941-01LIU, YANGUNIVERSITY OF UTAH, UT$385,000MRAA
2023Development of a Chemical Biology Toolbox to Investigate Histone Monoaminylation1R35GM150676-01ZHENG, QINGFEIOHIO STATE UNIVERSITY, OH$384,365ZRG1
2023MIRA: C(sp3)-H Heteroatom Incorporation Using Photoexcited Nitroarenes1R35GM150777-01PARASRAM, MARVINNEW YORK UNIVERSITY, NY$384,092ZRG1
2023Genetic mechanisms of signal integration in the nutrient sensing network1R35GM150926-01HUBERMAN, LORI BCORNELL UNIVERSITY, NY$384,034ZRG1
2023Regulatory Mechanisms Linking Spatial Gene Control and Genome Organization1R35GM150636-01NAIR, SREEJITH JANARDHANANGEORGETOWN UNIVERSITY, DC$383,840ZRG1
2023Measuring and Learning from Care Variation in Sepsis1R35GM151147-01PELTAN, ITHAN DANIELIHC HEALTH SERVICES, INC., UT$383,750MRAD
2023The role of XPO1 in nuclear export of RNA1R35GM151109-01TAYLOR, JUSTINUNIVERSITY OF MIAMI SCHOOL OF MEDICINE, FL$383,750ZRG1
2023Molecular Mechanism of TET-mediated Gene Regulation1R35GM151110-01LIO, JERRY CHAN-WANGOHIO STATE UNIVERSITY, OH$383,571MRAA
2023Gene positioning and dynamic chromatin organization of the human genome1R35GM151095-01TU, LI-CHUNOHIO STATE UNIVERSITY, OH$383,274ZRG1
2023From here to eternity: gut microbial response to drug therapy and inflammation1R35GM151349-01NAYAK, RENUKA RAJENDRANORTHERN CALIFORNIA INSTITUTE/RES/EDU, CA$383,250ZRG1
2023Deciphering Cellular Heterogeneity and Inheritability in Migration1R35GM150509-01CHEN, YU-CHIHUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$383,134MRAC
2023Genetically Manipulating Protein Expression to Probe 3D Cell Behavior using Ultrasound-Responsive Biomaterials1R35GM151057-01IBSEN, CAROLYN SCHUTTOREGON HEALTH & SCIENCE UNIVERSITY, OR$383,107ZRG1
2023Decoding Microbial Diversity in the Human Gut Microbiome1R35GM151045-01BISANZ, JORDAN ADAMPENNSYLVANIA STATE UNIVERSITY, THE, PA$383,000ZRG1
2023Understanding predictability of evolutionary trajectories1R35GM151058-01RENNISON, DIANA JESSIEUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$382,696ZRG1
2023Mechanistic insights into multifaceted roles of coronavirus exoribonuclease complex1R35GM150607-01YANG, YANGIOWA STATE UNIVERSITY, IA$382,500MRAB
2023Glycoscience Tools and Therapeutics1R35GM151083-01FARRELL, MARK PATRICKUNIVERSITY OF KANSAS LAWRENCE, KS$382,500ZRG1
2023Revealing forces driving collective cell migration1R35GM151171-01NOTBOHM, JACOB KUNIVERSITY OF WISCONSIN-MADISON, WI$382,090ZRG1
2023Surface adaptation in bacterial cells1R35GM150652-01HERSHEY, DAVID M.UNIVERSITY OF WISCONSIN-MADISON, WI$382,090ZRG1
2023Mechanisms of endosomal trafficking in lipid droplet catabolism1R35GM150801-01SCHOTT, MICAHUNIVERSITY OF NEBRASKA MEDICAL CENTER, NE$381,931ZRG1
2023Learning How to Give Casual Explanations for Large Scale Virtual and Morphological Pharmacology1R35GM151129-01O'MEARA, MATTHEW JUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$381,889ZRG1
2023Elucidating the dynamical and structural molecular factors at the origin of non-enzymatic protein-protein and protein-DNA cross-links1R35GM150409-01VAISSIER WELBORN, VALERIEVIRGINIA POLYTECHNIC INST AND ST UNIV, VA$381,824MRAB
2023When genomes collide: using hybrid zones to transform our understanding of behavioral and speciation genetics.1R35GM151012-01DELMORE, KIRATEXAS A&M UNIVERSITY, TX$381,250MRAA
2023Elucidating Molecular Mechanisms Underlying Cooperation in Animal-Bacterial Symbioses1R35GM150478-01HEATH-HECKMAN, ELIZABETH A.MICHIGAN STATE UNIVERSITY, MI$381,100ZRG1
2023Protein Transport Across Membrane by Bacterial Pathogens1R35GM150663-01DURIE, CLARISSA LYNNUNIVERSITY OF MISSOURI-COLUMBIA, MO$380,802ZRG1
2023Post-transcriptional regulation of cell plasticity1R35GM150760-01KHOSHNEVIS, SOHAILEMORY UNIVERSITY, GA$380,261ZRG1
2023Characterizing and modeling the genomewide molecular basis of gene-environment interactions1R35GM151048-01GAGE, JOSEPH LEENORTH CAROLINA STATE UNIVERSITY RALEIGH, NC$380,000ZRG1
2023Dissecting the genetics and evolution of complex traits using whole-genome genealogies1R35GM150579-01WEI, XINZHUCORNELL UNIVERSITY, NY$379,802ZRG1
2023Evolutionary Systems Biology of Host-Parasite Interactions1R35GM151194-01GROEN, SIMON CORNELISUNIVERSITY OF CALIFORNIA RIVERSIDE, CA$379,347ZRG1
2023Immunodiversity of plant receptor kinase networks for synthetic circuit design1R35GM151272-01STEINBRENNER, ADAM DUNIVERSITY OF WASHINGTON, WA$379,321ZRG1
2023Cell Control via Spatiotemporal Microenvironmental pH Modulation1R35GM151128-01PING, JINGLEIUNIVERSITY OF MASSACHUSETTS AMHERST, MA$379,245ZRG1
2023Defining the protein sequence features that control transcriptional activation domain function1R35GM150813-01STALLER, MAX VALENTINUNIVERSITY OF CALIFORNIA BERKELEY, CA$379,181ZRG1
2023Spatially Organized Bacterial Interaction Networks in the Gut Microbiota1R35GM150732-01PATNODE, MICHAEL LUNIVERSITY OF CALIFORNIA SANTA CRUZ, CA$378,567MRAA
2023Mechanistic insights into translesion synthesis-dependent genome instability1R35GM150992-01CHATTERJEE, NIMRATUNIVERSITY OF VERMONT & ST AGRIC COLLEGE, VT$378,240ZRG1
2023Determining the factors that impact single stranded DNA mutagenesis1R35GM151021-01SAINI, NATALIEMEDICAL UNIVERSITY OF SOUTH CAROLINA, SC$377,500ZRG1
2023Understanding inter-organellar communication in apicomplexan parasites1R35GM150794-01HUET, DIEGOUNIVERSITY OF GEORGIA, GA$377,500ZRG1
2023Investigating the molecular mechanisms of glycosaminoglycan assembly1R35GM150736-01WEISS, RYAN JOSEPHUNIVERSITY OF GEORGIA, GA$377,500MRAD
2023Understanding the specificity and non-native catalytic activity of PLP-dependent enzymes1R35GM151205-01HAI, YANGUNIVERSITY OF CALIFORNIA SANTA BARBARA, CA$377,350ZRG1
2023Direct and Quantitative Probing of Desmosome Mechanotransduction1R35GM150623-01YANG, RUIGUOUNIVERSITY OF NEBRASKA LINCOLN, NE$376,962ZRG1
2023Deciphering the mitochondrial proton leak1R35GM151226-01ZHANG, HUILIANGUNIV OF ARKANSAS FOR MED SCIS, AR$376,796MRAD
2023The origins and evolution of eukaryotic antibacterial defenses1R35GM150681-01LEVIN, TERA CATHERINEUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$376,200ZRG1
2023Integration of biophysics and deep learning to understand species-specificity of fertilization and the rapid evolution of protein disorder1R35GM150583-01WILBURN, DAMIEN BEAUOHIO STATE UNIVERSITY, OH$375,781MRAA
2023Molecular mechanisms of membrane protein homeostasis at the Golgi1R35GM150863-01SARDANA, RICHACORNELL UNIVERSITY, NY$375,716MRAD
2023Circadian output mechanisms in nocturnal and diurnal animals1R35GM151020-01JONES, JEFFREY RTEXAS A&M UNIVERSITY, TX$375,494MRAD
2023Interdisciplinary Studies for Mechanisms Underlying Social Isolation-Induced Health Critical Behavior Changes1R35GM150832-01LI, WANHETEXAS A&M UNIVERSITY, TX$375,494ZRG1
2023High spatiotemporal optical imaging to study dynamics of 3D cell motion and behavior in living organisms1R35GM150947-01LEE, JUHYUNUNIVERSITY OF TEXAS ARLINGTON, TX$375,440ZRG1
2023Mechanisms of Sleep Regulation in C. elegans1R35GM150658-01WANG, HANUNIVERSITY OF WISCONSIN-MADISON, WI$375,430MRAD
2023Neutrophil heterogeneity and plasticity in wound healing1R35GM150893-01DINH, HUY QUANGUNIVERSITY OF WISCONSIN-MADISON, WI$375,430MRAD
2023Bacterial ribosome heterogeneity and gene expression1R35GM150599-01RAMSEY, KATHRYN MARYUNIVERSITY OF RHODE ISLAND, RI$375,010ZRG1
2023Spatial metabolomics with subcellular resolution to identify therapeutic targets1R35GM150564-01GARTIA, MANAS RANJANLOUISIANA STATE UNIV A&M COL BATON ROUGE, LA$375,000ZRG1
2023Exploiting temperature-sensitive orthologs to understand protein allostery1R35GM150936-01THOMPSON, MICHAEL C.UNIVERSITY OF CALIFORNIA, MERCED, CA$374,874ZRG1
2023Regulation of mitochondrial morphology and functional versatility1R35GM150942-01AYDIN, HALILUNIVERSITY OF COLORADO, CO$374,862ZRG1
2023Interpretable Bayesian Non-linear statistical learning models for multi-omics data integration1R35GM150537-01CHEKOUO TEKOUGANG, THIERRYUNIVERSITY OF MINNESOTA, MN$374,672ZRG1
2023Large-scale phylodynamics under non-neutral and non-treelike models of evolution1R35GM151145-01TERHORST, JONATHAN GUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$374,491ZRG1
2023Cross-species Analysis of Bacterial Gene Networks1R35GM150487-01PETERS, JASON M.UNIVERSITY OF WISCONSIN-MADISON, WI$374,195ZRG1
2023Heterogeneous Directed Hydrogenation of Arenes and Olefins with Chemo- and Stereoselectivity1R35GM151120-01LI, CHRISTINA WPURDUE UNIVERSITY, IN$373,827ZRG1
2023Molecular analysis of bacterial interactions1R35GM150870-01GARG, NEHAGEORGIA INSTITUTE OF TECHNOLOGY, GA$373,752MRAA
2023Deciphering microbial metalloenzyme functions in microaerobic host environments1R35GM150913-01RAJAKOVICH, LAUREN JULIAUNIVERSITY OF WASHINGTON, WA$373,652ZRG1
2023Enabled by drug delivery: Studying the role of brain-resident and infiltrating myeloid cell phenotype in brain damage associated with inflammatory disease1R35GM150970-01CLEGG, JOHN RUNIVERSITY OF OKLAHOMA, OK$373,297ZRG1
2023A novel framework for nanomedicine development1R35GM150758-01WILHELM, STEFANUNIVERSITY OF OKLAHOMA, OK$373,297ZRG1
2023Epigenetic and transcriptional mechanisms driving human pigmentation diversity1R35GM151086-01BAJPAI, VIVEK KUMARUNIVERSITY OF OKLAHOMA, OK$373,297ZRG1
2023Investigation of Long-Range Charge Transfer and Excited State Processes in Biochemical Systems1R35GM150874-01ACHARYA, ATANUSYRACUSE UNIVERSITY, NY$372,604ZRG1
2023The role of conformational dynamics of enveloped virus spike proteins in cell entry1R35GM151169-01LU, MAOLINUNIVERSITY OF TEXAS HLTH CTR AT TYLER, TX$372,500ZRG1
2023Dissecting subcellular and cellular organization by spatial molecular neighborhood networks1R35GM151028-01COSKUN, AHMET F.GEORGIA INSTITUTE OF TECHNOLOGY, GA$372,051MRAC
2023Dissecting metabolic control by cytosolic-mitochondrial NAD compartmentalization1R35GM151097-01KORY, NORAHARVARD SCHOOL OF PUBLIC HEALTH, MA$371,975MRAD
2023Interrogating function, regulation, and interactions in a clade of prevalent human gut microbes1R35GM151155-01BRADLEY, PATRICK JOSEPHOHIO STATE UNIVERSITY, OH$371,738ZRG1

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