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NIH funding notice PAR-20-131

Research Projects to Enhance Applicability of Mammalian Models for Translational Research (R01 Clinical Trial Not Allowed)

Closed on May 7, 2023.

Posted
March 12, 2020
Close date
May 7, 2023
Activity codes
Not stated on the notice page
Institutes taking part
Not stated on the notice page

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

Its page was not saved, so the notices it replaced are not known.

Who won it before

29 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $15,767,166 in first-year total cost, median $578,670.

Most frequent study sections

  1. Special Emphasis Panel[ZRG1 CTH-E (55)]9
  2. Special Emphasis Panel[ZRG1 OTC-N (55)]9
  3. Special Emphasis Panel[ZRG1 OTC1-J (55)]8
  4. Special Emphasis Panel[ZRG1 CTH-B (55)]3

Most frequent institutions

  1. BAYLOR COLLEGE OF MEDICINE3
  2. UNIVERSITY OF ALABAMA AT BIRMINGHAM2
  3. UT SOUTHWESTERN MEDICAL CENTER2
  4. WEILL MEDICAL COLL OF CORNELL UNIV2
  5. BETH ISRAEL DEACONESS MEDICAL CENTER1
Competing awards under PAR-20-131 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2024Cross-species development and credentialing of pediatric AML models1R01CA285272-01KLCO, JEFFERY MMAGEE, JEFFREY ALANWASHINGTON UNIVERSITY, MO$665,385ZRG1
2024Construction of A Lung Cancer Preclinical Model Cross-comparison Platform1R01CA285336-01CAI, LINGUT SOUTHWESTERN MEDICAL CENTER, TX$627,833ZRG1
2024Culture of tumor versus normal cells1R01CA285335-01INCE, TAN A.WEILL MEDICAL COLL OF CORNELL UNIV, NY$364,140ZRG1
2024Defining Cancer Intervention Targets by Functional Genomics Analysis of Outbred F1 Mice1R01CA278818-01A1JACOB, JENNIFER BKIDDER, BENJAMIN LWAYNE STATE UNIVERSITY, MI$88,693ZRG1
2023Understanding the cellular and functional changes in the immune tumor microenvironment of glioblastoma during progression and treatments.1R01CA271601-01A1BOUSSIOTIS, VASSILIKI ACHAREST, ALAINVERHAAK, ROEL GWBETH ISRAEL DEACONESS MEDICAL CENTER, MA$672,634ZRG1
2023Genetically engineered mouse model to improve therapy of NUT carcinoma1R01CA285308-01FRENCH, CHRISTOPHER AKESKIN, DERIN BSHAPIRO, GEOFFREY IBRIGHAM AND WOMEN'S HOSPITAL, MA$672,468ZRG1
2023"Novel Mouse Models for Quantitative Understanding of Baseline and Therapy-Driven Evolution of Prostate Cancer Metastasis"1R01CA272466-01A1NOWAK, DAWID GRZEGORZWEILL MEDICAL COLL OF CORNELL UNIV, NY$657,652ZRG1
2023In vivo prime editing for precision cancer mouse models1R01CA275945-01A1XUE, WENUNIV OF MASSACHUSETTS MED SCH WORCESTER, MA$625,607ZRG1
2023preclinical optimization of BCMA directed T cell therapy1R01CA272426-01A1BERGSAGEL, PETER LEIFCHESI, MARTAMAYO CLINIC ARIZONA, AZ$621,878ZRG1
2023Optimizing Syngeneic Mouse Models to Target Mutant p531R01CA278089-01A1LI, YONGBAYLOR COLLEGE OF MEDICINE, TX$596,803ZRG1
2023Clinical, molecular, and immune characterization of naturally occurring osteosarcoma in dogs1U01CA281905-01REBHUN, ROBERT BUNIVERSITY OF CALIFORNIA AT DAVIS, CA$584,628ZRG1
2023A new mouse model for studying the pathogenesis and immunobiology of intrahepatic cholangiocarcinoma and improving its immunotherapy1R01CA281784-01KARIN, MICHAELUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$563,902ZRG1
2022Gamma delta T cell based melanoma therapies1R01CA258113-01A1HERLYN, MEENHARD FXU, XIAOWEIUNIVERSITY OF PENNSYLVANIA, PA$666,701ZRG1
2022Site-specific Integration of Large (10-100 kb) DNA Constructs into the Mouse Genome and Human Induced Pluripotent Stem Cells Using the Cas9-Bxb1 Integrase Toolbox1R01CA265978-01A1HOSUR, VISHNUJACKSON LABORATORY, ME$646,321ZRG1
2022Credentialing next-generation human glioma models for precision therapeutics1R01CA258248-01A1FURNARI, FRANKMILLER, CHRISTOPHER RYANO'ROURKE, DONALD MUNIVERSITY OF ALABAMA AT BIRMINGHAM, AL$618,530ZRG1
2022Next Generation Rat Models of ER+ Breast Cancer1R01CA271498-01LI, YIZHANG, XIANGBAYLOR COLLEGE OF MEDICINE, TX$612,175ZRG1
2022Escape from CAR T surveillance through lineage plasticity1R01CA269269-01ERNST, PATRICIAFRY, TERRY J.UNIVERSITY OF COLORADO DENVER, CO$578,670ZRG1
2022Loss of NF1 drives hormone dependent mammary carcinogenesis in a rat model with intact immune system1R01CA265933-01A1KESTERSON, ROBERT AWALLIS-SCHULTZ, DEEANNUNIVERSITY OF ALABAMA AT BIRMINGHAM, AL$547,183ZRG1
2022Polymerase epsilon-based mouse and derived organoid models of intestinal cancer1R01CA265884-01CASTRILLON, DIEGO HUT SOUTHWESTERN MEDICAL CENTER, TX$493,934ZRG1
2022Engineering Large Chromosomal Deletions in Mice to Advance Precision Oncology1R01CA261949-01A1CHEN, MINGDUKE UNIVERSITY, NC$416,540ZRG1
2021Investigation of the role of epithelial-mesenchymal plasticity in renal cell carcinoma1R01CA258226-01GENOVESE, GIANNICOLAUNIVERSITY OF TX MD ANDERSON CAN CTR, TX$591,326ZRG1
2021Credentialing Models of Invasive Lobular Breast Cancer for Translational Research1R01CA252378-01A1LEE, ADRIAN VOESTERREICH, STEFFIUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$573,041ZRG1
2021New mouse model of cisplatin-induced AKI and development of prevention therapy1R01CA251141-01A1ZHAO, JIANJUNCLEVELAND CLINIC LERNER COM-CWRU, OH$560,614ZRG1
2021Lentiviral-Induced Swine Model of Spinal Cord Glioma1R01CA251393-01A1BOULIS, NICHOLAS MCANOLL, PETEREMORY UNIVERSITY, GA$541,702ZRG1
2021Improving the translational value of head and neck cancer patient-in-mouse models1R37CA255330-01A1KIMPLE, RANDALL J.UNIVERSITY OF WISCONSIN-MADISON, WI$520,953ZRG1
2021Canine MHC-I genotyping and tumor specific neoantigen determination1R01CA252713-01A1HILDEBRAND, WILLIAMZHAO, SHAYINGUNIVERSITY OF GEORGIA, GA$492,039ZRG1
2021Comparative modeling of sarcoma microenvironments for the discovery of biomarkers and tumor vulnerabilities1R01CA258265-01GUARNERIO, JLENIACEDARS-SINAI MEDICAL CENTER, CA$443,656ZRG1
2021Epigenetically Engineered Mouse Model for Lung Cancer Therapy1R01CA261723-01SHEN, LANLANBAYLOR COLLEGE OF MEDICINE, TX$365,308ZRG1
2021Development of 3-dimensional human pituitary corticotroph tumor cultures as a preclinical model for drug discovery1R01CA251930-01A1HEANEY, ANTHONY PUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$356,850ZRG1

Data: Grants.gov's daily extract and NIH's notice pages and award files, in ScienceGraph release conductgrants-2026-11-09-0.1.0. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.

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