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NIH funding notice PAR-20-271

Assay development and screening for discovery of chemical probes, drugs or immunomodulators (R01 Clinical Trial Not Allowed)

Closed on January 7, 2023.

Posted
July 20, 2020
Close date
January 7, 2023
Activity codes
Not stated on the notice page
Institutes taking part
Not stated on the notice page

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

Its page was not saved, so the notices it replaced are not known.

Who won it before

21 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $12,173,124 in first-year total cost, median $569,944.

Most frequent study sections

  1. Special Emphasis Panel[ZRG1 BST-F (55)]8
  2. Special Emphasis Panel[ZRG1 OBT-Y (56)]6
  3. Drug Discovery and Molecular Pharmacology Study Section[DMP]2
  4. Special Emphasis Panel[ZRG1 BST-W (55)]2
  5. Drug Discovery and Molecular Pharmacology B Study Section[DMPB]1

Most frequent institutions

  1. SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE2
  2. BAYLOR COLLEGE OF MEDICINE1
  3. BECKMAN RESEARCH INSTITUTE/CITY OF HOPE1
  4. BRIGHAM AND WOMEN'S HOSPITAL1
  5. BROAD INSTITUTE, INC.1
Competing awards under PAR-20-271 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2023Targeting the mutant promoter of Telomerase Reverse Transcriptase (TERT)1R01CA275078-01A1JACKSON, MICHAELTHEODORESCU, DANCEDARS-SINAI MEDICAL CENTER, CA$772,180DMP
2023Identification of small molecule inhibitors of the DDI2 protease1R01CA279255-01KLEIGER, GARY L.RADHAKRISHNAN, SENTHIL KUMARSERGIENKO, EDUARD A.VIRGINIA COMMONWEALTH UNIVERSITY, VA$730,979DMP
2023Development of Kv3.1 potentiators for correcting fast-spiking-interneuron hypofunction in schizophrenia and autism spectrum disorder1R01MH131721-01A1DENTON, JEROD S.VANDERBILT UNIVERSITY MEDICAL CENTER, TN$695,775DMPB
2023Discovery of Novel Inhibitors Targeting trans-Golgi Network Acidification in Pancreatic Cancer1R01CA276193-01COMMISSO, COSIMOHEYNEN-GENEL, SUSANNESANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE, CA$647,398ZRG1
2023Identification of small molecule inhibitors to exonuclease 1 for breast cancer treatment1U01CA276195-01A1HORNE, DAVID A.SHEN, BINGHUIBECKMAN RESEARCH INSTITUTE/CITY OF HOPE, CA$575,395DMPC
2023Screening for inhibitors of NSD3 as a treatment for lung cancer1R01CA276074-01GREMBECKA, JOLANTAUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$529,475ZRG1
2022Small molecule enhancers of tumor immunity targeting the LPA5 GPCR1R01CA266207-01A1AUGELLI-SZAFRAN, CORINNE ELIZABETHLEE, SUE CHINTIGYI, GABOR JTORRES, RAUL MARTINUNIVERSITY OF TENNESSEE HEALTH SCI CTR, TN$861,845ZRG1
2022Targeting Postsynaptic Small G-protein Regulators1R01MH130838-01LUAN, CHI-HAOPENZES, PETERNORTHWESTERN UNIVERSITY AT CHICAGO, IL$733,531ZRG1
2022Targeting platinum(IV) prodrug to GBM tumors using a brevican-binding peptide1R01CA272573-01CHO, CHOI-FONGBRIGHAM AND WOMEN'S HOSPITAL, MA$701,557ZRG1
2022Development of p300/CBP histone acetyltransferase inhibitors for oncogene-driven cancers1R01CA266642-01HAHN, WILLIAM C.BROAD INSTITUTE, INC., MA$682,670ZRG1
2022Identification and characterization of chemical probes for interrogation of the NEK family of kinases in cancer1R01CA273095-01BUROW, MATTHEW E.DREWRY, DAVID HAROLDNEWMAN, ROBERT HOWARDUNIV OF NORTH CAROLINA CHAPEL HILL, NC$636,146ZRG1
2022Discovery of Glutaryl-CoA Dehydrogenase inhibitors for melanoma and pancreatic cancer1R01CA266828-01SERGIENKO, EDUARD A.SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE, CA$569,944ZRG1
2022Discovery of small molecule inhibitors for protein N-terminal acetyltransferase D1R01CA258887-01A1HUANG, RONGPURDUE UNIVERSITY, IN$559,725ZRG1
2022Development of a generalizable chemo-proteomics screening platform for small molecule degraders applied to HDACs1R01CA262188-01A1FISCHER, ERIC SEBASTIANDANA-FARBER CANCER INST, MA$487,238ZRG1
2022High Throughput Screen for Inhibitors of the YEATS2 Histone Acylation Reader1R01CA268440-01SHI, XIAOBINGVAN ANDEL RESEARCH INSTITUTE, MI$445,463ZRG1
2022Small molecules to target the RNA methyltransferase complex METTL3/METTL141R01CA258589-01A1NAM, YUNSUNUT SOUTHWESTERN MEDICAL CENTER, TX$440,678ZRG1
2022Novel Small-Molecule Probes Targeting Oncogenic Fusion MLL in Pediatric Leukemia1R01CA266057-01SONG, YONGCHENGBAYLOR COLLEGE OF MEDICINE, TX$437,571ZRG1
2022High Throughput Screening for SCAP Inhibitors as Pancreas Cancer Therapeutics1R01CA272789-01ESPENSHADE, PETER J.JOHNS HOPKINS UNIVERSITY, MD$405,491ZRG1
2021A Fragment-Based Strategy for K-RAS Covalent Inhibitors1R01CA264471-01MEROUEH, SAMYINDIANA UNIVERSITY INDIANAPOLIS, IN$469,217ZRG1
2021High-Throughput Screen for the Oncoprotein MYC1R01CA262290-01JANDA, KIMSCRIPPS RESEARCH INSTITUTE, THE, CA$432,947ZRG1
2021Discovery of small molecule mutant SMAD4-PPI inducers1R37CA255459-01A1MO, XIULEIEMORY UNIVERSITY, GA$357,899ZRG1

Data: Grants.gov's daily extract and NIH's notice pages and award files, in ScienceGraph release conductgrants-2026-11-09-0.1.0. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.

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PAR-20-271: Assay development and screening for discovery of chemical probes, drugs or immunomodulators (R01 Clinical Trial Not Allowed) | ScienceDex | ConductScience