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NIH funding notice PAR-21-137

Early Stage Testing of Pharmacologic or Device-based Interventions for the Treatment of Mental Disorders (R61/R33 Clinical Trial Required)

Closed on October 15, 2024.

Posted
March 2, 2021
Close date
October 15, 2024
Activity codes
R61, R33
Institutes taking part
NIMH

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

  1. Reissues: RFA-MH-18-702 Early Stage Testing of Pharmacologic or Device-based Interventions for the Treatment of Mental Disorders (R61/R33-Clinical Trial Required)
  2. 2 steps back: RFA-MH-17-600 Early Stage Testing of Pharmacologic or Device-based Interventions for the Treatment of Mental Disorders (R61/R33)

Replaced by PAR-25-184.

Who won it before

25 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $26,411,493 in first-year total cost, median $968,769.

Most frequent study sections

  1. Special Emphasis Panel[ZMH1 ERB-B (01)]4
  2. Special Emphasis Panel[ZMH1 ERB-R (02)]4
  3. Special Emphasis Panel[ZMH1 ERB-D (02)]3
  4. Special Emphasis Panel[ZMH1 ERB-R (03)]3
  5. Special Emphasis Panel[ZMH1 ERB-S (06)]3

Most frequent institutions

  1. UNIVERSITY OF CALIFORNIA, SAN DIEGO5
  2. MASSACHUSETTS GENERAL HOSPITAL2
  3. UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON2
  4. CENTRE FOR ADDICTION AND MENTAL HEALTH1
  5. CINCINNATI CHILDRENS HOSP MED CTR1
Competing awards under PAR-21-137 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2025Cannabidiol-enhanced cognitive behavioral therapy for generalized anxiety disorder1R61MH137105-01A1LUNDAHL, LESLIE HMARUSAK, HILARYRABINAK, CHRISTINE ANNEWAYNE STATE UNIVERSITY, MI$1,715,387ZMH1
2025Effect of Network-Based Real Time Neurofeedback Augmentation of Mindfulness Practice on Recurrent Negative Thinking in Adolescents at Risk for Serious Mental Illness1R61MH139856-01EVINS, A EDENWHITFIELD-GABRIELI, SUSANMASSACHUSETTS GENERAL HOSPITAL, MA$1,461,016ZMH1
2025Bilateral Prefrontal and Insular TMS for Depression in Schizophrenia1R61MH138703-01A1DU, XIAOMINGHONG, L ELLIOT ELLIOTUNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON, TX$1,125,194ZMH1
2025Maintenance rTMS for depression (Maitr-De)1R61MH138647-01DASKALAKIS, ZAFIRIS J.UNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$968,769ZMH1
2024Engaging the subgenual cingulate with brain stimulation for depression1R61MH135428-01OATHES, DESMONDUNIVERSITY OF PENNSYLVANIA, PA$1,633,082ZMH1
2024Noninvasive modulation of deep brain circuits for treatment-resistant depression1R61MH134943-01KUBANEK, JANMICKEY, BRIAN JAMESUNIVERSITY OF UTAH, UT$967,781ZMH1
2024Modulating spinal interoceptive pathways to evaluate their role and therapeutic potential in MDD symptomatic domains1R61MH133770-01A1ROMO-NAVA, FRANCISCOUNIVERSITY OF CINCINNATI, OH$898,025ZMH1
2024Mindfulness Engaged Neurostimulation for Depression (MEND)1R61MH136135-01MISHRA, JYOTIRAMANATHAN, DHAKSHINUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$888,768ZMH1
2024Ketogenic Diet in Weight Recovered Anorexia Nervosa to Target Metabolism and Normalize Persistent Eating Disorder Psychopathology1R61MH134909-01A1FRANK, GUIDO KWUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$884,103ZMH1
2024ADHD PreSMART: ADHD PreSMA Response inhibition Therapy1R61MH135994-01WU, STEVE WEICINCINNATI CHILDRENS HOSP MED CTR, OH$671,533ZMH1
2024Alternative Stimulation Mode and Location for Auditory Hallucination Neuromodulation Treatment1R61MH128390-01A1CHEN, SHUODU, XIAOMINGHONG, L ELLIOT ELLIOTUNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON, TX$565,921ZMH1
2023Targeting Dopamine-Mediated Social Reward Sensitivity to Remediate Social Disconnection1R61MH129380-01A1SCHNEIER, FRANKLIN R.TAYLOR, CHARLESUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$1,423,718ZMH1
2023Using Ketamine to enhance memory reconsolidation and extinction of overgeneralized fear in individuals diagnosed with PTSD1R61MH129559-01A1HARPAZ-ROTEM, ILANYALE UNIVERSITY, CT$1,241,319ZMH1
2023Transcranial Magnetic Stimulation to Augment Exposure and Response Prevention for Pediatric OCD1R61MH133666-01BENITO, KRISTEN GCONELEA, CHRISTINE AEMMA PENDLETON BRADLEY HOSPITAL, RI$1,224,725ZMH1
2023Suicide Circuit Therapeutics: Engaging Novel Targets with Rapid and Individualized MRI-Guided Accelerated TMS1R61MH132869-01CAMPRODON, JOAN AMASSACHUSETTS GENERAL HOSPITAL, MA$1,169,931ZMH1
2023Frequency and E-field Enhancement of iTBS for Depression (FREED)1R61MH129471-01A1DASKALAKIS, ZAFIRIS J.FITZGERALD, PAULUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$804,239ZMH1
2021Individually targeted neuromodulation for contamination-based OCD1R61MH121640-01A1 · under RFA-MH-18-702BRENNAN, BRIAN P.MCLEAN HOSPITAL, MA$1,069,368ZMH1
2021Electroconvulsive therapy amplitude titration for improved clinical outcomes in late-life depression1R61MH125126-01 · under RFA-MH-18-702ABBOTT, CHRISTOPHER CUNIVERSITY OF NEW MEXICO HEALTH SCIS CTR, NM$756,111ZMH1
2020Dopaminergic Therapy for Inflammation-Related Anhedonia in Depression1R61MH121625-01A1 · under RFA-MH-18-702FELGER, JENNIFER CEMORY UNIVERSITY, GA$1,406,314ZMH1
2020Transcranial Magnetic Stimulation to Augment Behavior Therapy for Tics1R61MH123754-01 · under RFA-MH-18-702CONELEA, CHRISTINE AUNIVERSITY OF MINNESOTA, MN$1,248,895ZMH1
2020Neuromodulation of Social Cognitive Circuitry in People with Schizophrenia Spectrum Disorders1R61MH120188-01A1 · under RFA-MH-18-702BLUMBERGER, DANIEL M.VOINESKOS, ARISTOTLE NICHOLASCENTRE FOR ADDICTION AND MENTAL HEALTH, ON$1,026,903ZMH1
2020Nicotinic Modulation of the Cognitive Control System in Late-Life Depression1R61MH122464-01 · under RFA-MH-18-702TAYLOR, WARREN DVANDERBILT UNIVERSITY MEDICAL CENTER, TN$946,653ZMH1
2020Transcranial Near Infrared Radiation and Cerebral Blood Flow in Depression (TRIADE)1R61MH122647-01 · under RFA-MH-18-702CASSANO, PAOLOIOSIFESCU, DAN VLADNEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY$863,648ZMH1
2019Morning Light Treatment for Traumatic Stress: the Role of Amygdala Reactivity1R61MH117157-01A1 · under RFA-MH-18-702BURGESS, HELEN JULIAZALTA, ALYSON KAYUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$803,761ZMH1
2019D-serine augmentation of neuroplasticity-based auditory learning in schizophrenia1R61MH116093-01A1 · under RFA-MH-18-702KANTROWITZ, JOSHUA TOLKIENNEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC, NY$646,329ZMH1

Data: Grants.gov's daily extract and NIH's notice pages and award files, in ScienceGraph release conductgrants-2026-11-09-0.1.0. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.

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PAR-21-137: Early Stage Testing of Pharmacologic or Device-based Interventions for the Treatment of Mental Disorders (R61/R33 Clinical Trial Required) | ScienceDex | ConductScience