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NIH funding notice PAR-21-323

Basic Research in Cancer Health Disparities (R21 Clinical Trial Not Allowed)

Closed on September 7, 2024.

Posted
September 2, 2021
Close date
September 7, 2024
Activity codes
R21
Institutes taking part
NCI

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

  1. Reissues: PAR-18-655 Basic Research in Cancer Health Disparities (R21 Clinical Trial Not Allowed)
  2. 2 steps back: PAR-15-092 Exploratory/Developmental Grants Program for Basic Cancer Research in Cancer Health Disparities (R21)
  3. 3 steps back: PAR-12-094 Exploratory/Developmental Grants Program for Basic Cancer Research in Cancer Health Disparities (R21)
  4. 4 steps back: PAR-09-160 Exploratory/Developmental Grants Program for Basic Cancer Research in Cancer Health Disparities (R21)

Replaced by PAR-24-291.

Who won it before

62 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $13,809,615 in first-year total cost, median $206,400.

Most frequent study sections

  1. Basic Mechanisms of Cancer Health Disparities Study Section[BMCD]19
  2. Special Emphasis Panel[ZRG1 OBT-J (55)]11
  3. Special Emphasis Panel[ZRG1 OBT-Y (55)]9
  4. Special Emphasis Panel[ZRG1 OBT-Z (55)]9
  5. Special Emphasis Panel[ZRG1 OBT-B (55)]6

Most frequent institutions

  1. VIRGINIA COMMONWEALTH UNIVERSITY4
  2. H. LEE MOFFITT CANCER CTR & RES INST3
  3. ROSWELL PARK CANCER INSTITUTE CORP3
  4. WAYNE STATE UNIVERSITY3
  5. BAYLOR COLLEGE OF MEDICINE2
Competing awards under PAR-21-323 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2025Colonic bile acid metabolism and responses in African Americans and non-Hispanic Whites1R21CA280578-01A1KUPFER, SONIAUNIVERSITY OF CHICAGO, IL$228,382BMCD
2024Reducing prostate cancer mortality in African American men by early disease detection using DNA fragmentation profiles and methylated DNA patterns of plasma derived cell free DNA1R21CA292755-01SZALLASI, ZOLTANBOSTON CHILDREN'S HOSPITAL, MA$475,759BMCD
2024ATG16L1 isoforms and CRC health disparities1R21CA283138-01A1DENT, PAULVIRGINIA COMMONWEALTH UNIVERSITY, VA$399,187BMCD
2024Integrated Genomic-Transcriptomic Characterization to Identify Molecular Mechanisms of Disparities in PDAC Outcomes1R21CA267124-01A1DUDEJA, VIKASUNIVERSITY OF ALABAMA AT BIRMINGHAM, AL$362,050BMCD
2024Functional state of CD8+ T cell immunity in adult T-cell leukemia/lymphoma1R21CA290322-01LAUVAU, GREGOIRE STEPHANEYE, BIHUI HILDAALBERT EINSTEIN COLLEGE OF MEDICINE, NY$235,620TIR
2024Analysis of a missense SNP in the aryl hydrocarbon receptor repressor gene that may disproportionately increase lung cancer risk in Black Americans1R21CA290319-01OFFRINGA, ITE AUNIVERSITY OF SOUTHERN CALIFORNIA, CA$232,640BMCD
2024Developing Acute Myeloid Leukemia Models with Diverse Ancestral Origins1R21CA283135-01A1PARDEE, TIMOTHY SEBASTIANWAKE FOREST UNIVERSITY HEALTH SCIENCES, NC$213,594BMCD
2024Identification of metabolic niches in African Americans with colorectal cancer1R21CA280372-01A1JOHNSON, CAROLINE HELENKHAN, SAJID AYALE UNIVERSITY, CT$195,766BMCD
2024Ethnicity-driven pfeRNA in African American health disparities in lung cancer.1R21CA290334-01MEI, YUPINGJOHNS HOPKINS UNIVERSITY, MD$191,383BMCD
2024Explainable AI-Based Multi-Omics Analysis of Lung Cancer Health Disparity1R21CA290324-01MONDAL, ANANDA MOHANFLORIDA INTERNATIONAL UNIVERSITY, FL$168,125BMCD
2024Contribution of Cellular and Molecular Heterogeneity of Esophageal Epithelium to Health Disparities in Esophageal Cancer1R21CA290137-01REICHENBACH, ZACHARY WWHELAN, KELLY ATEMPLE UNIV OF THE COMMONWEALTH, PA$1BMCD
2023Mitochondrial Dysfunction underlies treatment related hepatotoxicity in Hispanics with acute lymphoblastic leukemia1R21CA274416-01A1ALACHKAR, HOUDAUNIVERSITY OF SOUTHERN CALIFORNIA, CA$442,404BMCD
2023Racial Disparities and Colorectal DNA Methylation- Driven Gene Expression1R21CA283132-01LI, LIUNIVERSITY OF VIRGINIA, VA$415,257BMCD
2023Assessing healthy breast tissue for evidence of ancestry-dependent molecular contributions to TNBC disparities1R21CA280575-01RIGOUTSOS, ISIDORETHOMAS JEFFERSON UNIVERSITY, PA$413,815BMCD
2023Genomics of Renal Cancer in Patients of African Ancestry1R21CA280577-01TAYLOR, ALISON M.ZHANG, JIANSLOAN-KETTERING INST CAN RESEARCH, NY$263,285BMCD
2023Landscape and characterization of promoter mutations driving triple-negative breast cancer1R21CA284602-01ELLISEN, LEIF WRHEINBAY, ESTHERMASSACHUSETTS GENERAL HOSPITAL, MA$249,749BMCD
2023SQLE and Sterols Contribute to Racial Disparity in ER+ Breast Cancer Patient Survival1R21CA276820-01FRASOR, JONNAHOSKINS, KENTUNIVERSITY OF ILLINOIS AT CHICAGO, IL$238,200ZRG1
2023Role of SLAMF7 in Racial Disparities in Myeloma1R21CA280499-01KANG, YUBINDUKE UNIVERSITY, NC$234,835BMCD
2023Development of Mouse and Humanized Models to Study Sex Disparities in Tumor Progression and Treatment of NSCLC1R21CA283631-01LANDRY, JOSEPH WILLIAMVIRGINIA COMMONWEALTH UNIVERSITY, VA$217,738BMCD
2023Novel therapeutic approaches to remediate radiotherapy-induced bone necrosis1R56CA283140-01AKINTOYE, SUNDAY OUNIVERSITY OF PENNSYLVANIA, PA$200,000BMCD
2023Role and Theranostics Potential of Enolase in Prostate Cancer Health Disparities1R21CA280647-01ALMAGUEL, FRANKIE GCASIANO, CARLOS A.DAS, BHASKAR CHANDRALOMA LINDA UNIVERSITY, CA$186,539ZRG1
2023Emerging role of tumor-derived exosomes in immune modulation and breast cancer health disparity.1R21CA283524-01CHAUDHARY, PANKAJUNIVERSITY OF NORTH TEXAS HLTH SCI CTR, TX$172,975BMCD
2022Tumor and immune cell co-evolutionary dynamics as a source of racial disparities in breast cancer1R21CA267002-01A1OMILIAN, ANGELAROSWELL PARK CANCER INSTITUTE CORP, NY$243,334ZRG1
2022Molecular Drivers of Lung Cancer in Hispanics1R21CA259215-01A1 · under PAR-18-655CRESS, WILLIAM DOUGLASTEER, JAMIE KH. LEE MOFFITT CANCER CTR & RES INST, FL$236,321ZRG1
2022The primary role of low NCOA6 expression in the prostate cancer disparity among African American men1R21CA267006-01 · under PAR-18-655XU, JIANMINGBAYLOR COLLEGE OF MEDICINE, TX$224,400ZRG1
2022Mitochondrial dysfunction and chronic stress intersect as mechanisms driving breast cancer racial disparities1R21CA267975-01A1SHOCK, LISA SALEZHAO, HUAVIRGINIA COMMONWEALTH UNIVERSITY, VA$217,738ZRG1
2022L1 element mutagenesis as a driver of epithelial cancers in African Americans1R21CA259309-01A1 · under PAR-18-655DEVINE, SCOTT EUNIVERSITY OF MARYLAND BALTIMORE, MD$216,686ZRG1
2022The ODC A allele as a driver and therapeutic target of aggressive prostate cancer in African American men1R21CA253343-01A1 · under PAR-18-655PARK, JONG Y.H. LEE MOFFITT CANCER CTR & RES INST, FL$196,934ZRG1
2022Defining the landscape of structural alterations in African American Multiple Myeloma1R21CA273773-01BOISE, LAWRENCE H.EMORY UNIVERSITY, GA$182,909ZRG1
2022Characterization of metastasis models derived from breast cancer patients of African descent1R21CA273779-01HARRELL, JOSHUA (CHUCK)VIRGINIA COMMONWEALTH UNIVERSITY, VA$181,448ZRG1
2021Discovery of H. pylori T cell epitopes unique to minority populations that could contribute to increased gastric cancer rates.1R21CA248804-01A1 · under PAR-18-655SETTLES, ERIK WNORTHERN ARIZONA UNIVERSITY, AZ$438,168ZRG1
2021Are racial disparities in colon cancer due to epigenetic outliers.1R21CA264213-01 · under PAR-18-655GHOSH, JAYASHRISAPIENZA, CARMENTEMPLE UNIV OF THE COMMONWEALTH, PA$222,296ZRG1
2021DNA Damage and Repair Mechanisms, Obesity, and Breast Cancer Disparities1R21CA264489-01 · under PAR-18-655DASH, CHIRANJEEVROY, RABINDRAGEORGETOWN UNIVERSITY, DC$218,790ZRG1
2020Tumor microenvironment at single cell level in black and white NSCLC patients1R21CA253362-01 · under PAR-18-655LIU, LIANGZHANG, WEIWAKE FOREST UNIVERSITY HEALTH SCIENCES, NC$398,545ZRG1
2020CELL POPULATION HETEROGENEITY IN TRIPLE NEGATIVE BREAST CANCER DISPARITIES1R21CA238066-01A1 · under PAR-18-655STERN, DAVID FYALE UNIVERSITY, CT$218,588ZRG1
2019DHFRP1 pseudogene status as a biomarker of chemotherapy response and outcomes in African-American breast cancer patients1R21CA231847-01A1 · under PAR-18-655BOWER, JACQUELYN JUNIV OF NORTH CAROLINA CHAPEL HILL, NC$202,928ZRG1
2019Glucocorticoid signaling, taxane resistance, and prostate cancer mortality disparity1R21CA226654-01A1 · under PAR-18-655CASIANO, CARLOS A.LOMA LINDA UNIVERSITY, CA$171,825ZRG1
2018Vitamin D Deficiency Leads to Increased Intra-Prostatic Androgens in African American Men1R21CA231610-01 · under PAR-15-092NONN, LARISAUNIVERSITY OF ILLINOIS AT CHICAGO, IL$208,670ZRG1
2018Prostate Cancer Susceptibility Gene Identification in Chromosome 5 Candidate Region1R21CA220311-01A1 · under PAR-15-092BOCK, CATHRYN HBOERNER, JULIE LYNNWAYNE STATE UNIVERSITY, MI$178,029ZRG1
2017Inter-relationship between microbiota diversity, obesity and race in endometrial cancer1R21CA220269-01 · under PAR-15-092BAE-JUMP, VICTORIA LINKEKU, TEMITOPE O.UNIV OF NORTH CAROLINA CHAPEL HILL, NC$202,928ZRG1
2017Stress Inflammation Mechanisms of Survivorship Disparities Experienced by Hispanic Women After Breast Cancer1R21CA215007-01 · under PAR-15-092PACE, THADDEUSUNIVERSITY OF ARIZONA, AZ$200,318ZRG1
2017Restoring ciliogenesis as a novel approach to blocking breast cancer growth1R21CA207659-01A1 · under PAR-15-092DYNLACHT, BRIAN DREITER, JEREMY FNEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY$196,577ZRG1
2017Host-environment interactions in colorectal cancer disparities1R21CA215380-01 · under PAR-15-092KUPFER, SONIAUNIVERSITY OF CHICAGO, IL$176,175ZRG1
2017The DARC side of Breast Cancer1R21CA210237-01A1 · under PAR-15-092DAVIS, MELISSA BUNIVERSITY OF GEORGIA, GA$34,545ZRG1
2016Genetic Signatures Underlying Prostate Cancer Metastasis in AfricanAmericans1R21CA199171-01A1 · under PAR-15-092FARUQUE, MEZBAH U.HOWARD UNIVERSITY, DC$229,898ZRG1
2015Racial Disparity of microRNA in Hepatitis C Virus Mediated Hepatocellularcarcinoma1R21CA188472-01A1 · under PAR-12-094RAY, RATNA B.SAINT LOUIS UNIVERSITY, MO$212,479ZRG1
2015Novel gene that determines metastatic phenotype in African-American men with PCa1R21CA184685-01A1 · under PAR-12-094BHAT, MOHAMMAD SALEEMUNIVERSITY OF MINNESOTA, MN$208,567ZRG1
2015Racial differences in CYP1B1 polymorphisms and risks for prostate cancer1R21CA185003-01A1 · under PAR-12-094TANAKA, YUICHIRONORTHERN CALIFORNIA INSTITUTE/RES/EDU, CA$200,057ZRG1
2015Roles of Semaphorin Signaling in Breast Cancer Racial Disparities1R21CA199586-01 · under PAR-12-094JIAO, KAIWANG, LIZHONGUNIVERSITY OF ALABAMA AT BIRMINGHAM, AL$191,835ZRG1
2015Germline Mutations in African American Families with Aggressive Prostate Cancer1R21CA185213-01A1 · under PAR-12-094LIU, WANGUOLSU HEALTH SCIENCES CENTER, LA$190,530ZRG1
2015Determining high risk HPV status in the underserved1R21CA199632-01 · under PAR-12-094MARSHALL, DANA ROBINMEHARRY MEDICAL COLLEGE, TN$189,878ZRG1
2015The role of exRNA in Health Disparity of Prostate Cancer1R21CA194750-01 · under PAR-12-094ABD ELMAGEED, ZAKARIATULANE UNIVERSITY OF LOUISIANA, LA$187,231ZRG1
2015Prostate Cancer Gene Identification within Candidate Region in African Americans1R21CA185087-01A1 · under PAR-12-094BOCK, CATHRYN HBOERNER, JULIE LYNNWAYNE STATE UNIVERSITY, MI$173,985ZRG1
2015Molecular Beacon-Based Nanoparticles for TNBC Imaging and Targeted Therapy1R21CA194295-01 · under PAR-12-094VISHWANATHA, JAMBOOR K.UNIVERSITY OF NORTH TEXAS HLTH SCI CTR, TX$158,775ZRG1
2015Exosomes Promote Disease aggressiveness in African American Prostate Cancer1R21CA199628-01 · under PAR-12-094DEEP, GAGANUNIVERSITY OF COLORADO DENVER, CO$52,595ZRG1
2014Metabotropic Glutamate Receptor 1 in African American Prostate Cancer1R21CA183892-01 · under PAR-12-094KOOCHEKPOUR, SHAHRIARROSWELL PARK CANCER INSTITUTE CORP, NY$221,589ZRG1
2014Obesity and prostate cancer risk in Black and White men: a functional approach1R21CA179659-01A1 · under PAR-12-094CHORNOKUR, GANNAH. LEE MOFFITT CANCER CTR & RES INST, FL$219,893ZRG1
2014High Kynurenine in Agressive Triple Negative African American Breast Cancer1R21CA185516-01 · under PAR-12-094SREEKUMAR, ARUNBAYLOR COLLEGE OF MEDICINE, TX$204,233ZRG1
2014Hippo signaling pathway in breast cancer disparities: a translational approach1R21CA179693-01A1 · under PAR-12-094ZHANG, JIANMINROSWELL PARK CANCER INSTITUTE CORP, NY$190,856ZRG1
2014Racial disparity of MIC-1 gene in prostate tumor biology1R21CA179733-01A1 · under PAR-12-094KARAN, DEVUNIVERSITY OF SOUTH CAROLINA AT COLUMBIA, SC$174,218ZRG1
2014Obesity and IGF-axis Activation in Native Hawaiian Women with Breast Cancer1R21CA176555-01A1 · under PAR-12-094LOO, LENORA WMUNIVERSITY OF HAWAII AT MANOA, HI$165,300ZRG1
2014Profiling Genetic Alterations in NSCLC in African Americans1R21CA184778-01 · under PAR-12-094GADGEEL, SHIRISHSCHWARTZ, ANN G.WAYNE STATE UNIVERSITY, MI$132,240ZRG1

Data: Grants.gov's daily extract and NIH's notice pages and award files, in ScienceGraph release conductgrants-2026-11-09-0.1.0. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.

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