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NIH funding notice PAR-21-359

Early and Late Stage Clinical Trials for the Spectrum of Alzheimers Disease/Alzheimers Related Dementias and Age-Related Cognitive Decline (R01 Clinical Trial Optional)

Closed on December 23, 2023.

Posted
January 10, 2022
Close date
December 23, 2023
Activity codes
Not stated on the notice page
Institutes taking part
Not stated on the notice page

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

Its page was not saved, so the notices it replaced are not known.

Who won it before

17 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $21,532,457 in first-year total cost, median $766,880.

Most frequent study sections

  1. Adult Psychopathology and Disorders of Aging Study Section[APDA]4
  2. Aging Systems and Geriatrics Study Section[ASG]3
  3. Lifestyle Change and Behavioral Health Study Section[LCBH]2
  4. Aging, Injury, Musculoskeletal, and Rheumatologic Disorders Study Section[AIMR]1
  5. Biobehavioral Medicine and Health Outcomes Study Section[BMHO]1

Most frequent institutions

  1. ARIZONA STATE UNIVERSITY-TEMPE CAMPUS1
  2. BAYLOR UNIVERSITY1
  3. BOSTON UNIVERSITY (CHARLES RIVER CAMPUS)1
  4. CALIFORNIA PACIFIC MED CTR RES INSTITUTE1
  5. EIP PHARMA, INC.1
Competing awards under PAR-21-359 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2023A Phase 2b Clinical Study of the P38 Alpha Kinase Inhibitor Neflamapimod in Patients with Mild-to-Moderate Dementia with Lewy Bodies (DLB)1R01AG080536-01ALAM, JOHNGALVIN, JAMES EEIP PHARMA, INC., MA$6,682,055APDA
2023Effects of Successful OSA TreatmENT on Memory and AD BIomarkers in Older AduLts (ESSENTIAL)1R01AG080609-01A1OSORIO, RICARDO SSTONE, KATIE LVARGA, ANDREW WCALIFORNIA PACIFIC MED CTR RES INSTITUTE, CA$3,611,262LHB
2023Effect of Suvorexant on Alzheimer's Disease Biomarkers1R01AG080551-01LUCEY, BRENDAN PATRICKWASHINGTON UNIVERSITY, MO$1,595,468CNN
2023Cognitively engaging walking exercise and neuromodulation to enhance brain function in older adults1R01AG081477-01CLARK, DAVID JUNIVERSITY OF FLORIDA, FL$1,244,992APDA
2023ACTS (AD Clinical Trial Simulation): Developing Advanced Informatics Approaches for an Alzheimer's Disease Clinical Trial Simulation System1R01AG084236-01BIAN, JIANGTAO, CUIZHANG, GUO-QIANGUNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON, TX$1,155,311ZRG1
2023Precision Medicine in Alzheimer’s Disease: A SMART Trial of Adaptive Exercises and Their Mechanisms of Action Using AT(N) Biomarkers to Optimize Aerobic-Fitness Responses1R01AG076566-01A1YU, FANGARIZONA STATE UNIVERSITY-TEMPE CAMPUS, AZ$972,873ASG
2023mHealth-Facilitated Physical Activity Toward Health (mPATH) for Cognitive Function and Sleep in Low-Income Older Adults1R01AG080613-01A1LI, JUNXINJOHNS HOPKINS UNIVERSITY, MD$833,602ASG
2023Dual-Task Training Exercise to Reduce Falls in Older Adults with Mild Cognitive Impairment1R01AG074045-01A1LI, FUZHONGOREGON RESEARCH INSTITUTE, OR$792,805LCBH
2023Smartphone-Based Solutions for Prospective Memory in Mild Cognitive Impairment and Dementia1R01AG082783-01BENGE, JARED FSCULLIN, MICHAEL KBAYLOR UNIVERSITY, TX$766,880APDA
2023A Stage 1 Pilot Test for Feasibility and Efficacy of a Multi-Level Intervention To Increase Physical Activity in Adults with Intellectual Disability: Step it Up +1R01AG076678-01A1HUME, KARASAVAGE, MELISSA NOELTOMASZEWSKI, BRIANNEUNIV OF NORTH CAROLINA CHAPEL HILL, NC$763,588LCBH
2023Cannabidiol for Individuals at Risk for Alzheimer's Disease: A Randomized Placebo Controlled Trial1R01AG079502-01A1BRYAN, ANGELAHUTCHISON, KENT E.UNIVERSITY OF COLORADO DENVER, CO$733,468ZRG1
2023MIND Foods and Aerobic Training in Black Adults with HTN: An ADRD Prevention Pilot RCT (MAT)1R01AG076685-01A1CLARK, DANIEL OINDIANA UNIVERSITY INDIANAPOLIS, IN$686,422BMHO
2023Feasibility of Improving Glycemia to Prevent Alzheimer's Disease1R01AG081304-01GEIGER, PAIGE CMORRIS, JILL KATHLEENUNIVERSITY OF KANSAS MEDICAL CENTER, KS$477,602ASG
2023Novel Methods for Clinical Trials in Dementia and Cognitive Decline1R01AG080548-01ROYALL, DONALD RUNIVERSITY OF TEXAS HLTH SCIENCE CENTER, TX$463,746ZRG1
2023Personalized Synchronization of Cortical Rhythms to Improve Memory in Alzheimer's Disease1R01AG082645-01REINHART, ROBERTBOSTON UNIVERSITY (CHARLES RIVER CAMPUS), MA$412,500APDA
2023Longitudinal Associations of Electroconvulsive Therapy with Neuropsychiatric Symptoms, Geriatric Syndromes, and Nursing Home Admission and Mortality Rates among Adults with Dementia1R01AG080647-01A1RHEE, TAEHO GREGORYUNIVERSITY OF CONNECTICUT SCH OF MED/DNT, CT$339,882AIMR
2023Communication Bridge: Optimizing an evidence-based intervention for individuals with primary progressive aphasia2R01AG055425-06A1ROBERTS, ANGELA CHRISTINEROGALSKI, EMILY JNORTHWESTERN UNIVERSITY AT CHICAGO, IL$1LCOM

Data: Grants.gov's daily extract and NIH's notice pages and award files, in ScienceGraph release conductgrants-2026-11-09-0.1.0. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.

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