The notices it replaced
Its page was not saved, so the notices it replaced are not known.
Who won it before
150 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $50,028,747 in first-year total cost, median $336,815.
Most frequent study sections
- Special Emphasis Panel[ZRG1 AN-Q (55)]22
- Cellular and Molecular Biology of Neurodegeneration Study Section[CMND]13
- Special Emphasis Panel[ZRG1 AN-Z (55)]9
- Cellular and Molecular Biology of Glia Study Section[CMBG]8
- Neural Oxidative Metabolism and Death Study Section[NOMD]8
Most frequent institutions
- MASSACHUSETTS GENERAL HOSPITAL6
- UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON6
- ROSKAMP INSTITUTE, INC.4
- UNIVERSITY OF KENTUCKY4
- ARIZONA STATE UNIVERSITY-TEMPE CAMPUS3
| FY | Project | PIs | Institution | First-year cost | Study section |
|---|---|---|---|---|---|
| 2025 | Impact of Age-Related Clonal Hematopoiesis on Alzheimer's Disease1R21AG096415-01 | TELPOUKHOVSKAIA, MARIA | JACKSON LABORATORY, ME | $486,750 | ZRG1 |
| 2025 | FOXO3 dependent proinflammatory transcription program of AD1R21AG085675-01A1 | KIM, TAE-WANPAIK, JIHYE | COLUMBIA UNIVERSITY HEALTH SCIENCES, NY | $475,377 | CMBG |
| 2025 | Dysregulation of cortical astrocytes in models of Alzheimer's Disease1R21AG087186-01A1 | CARDIN, JESSICA A | YALE UNIVERSITY, CT | $461,146 | CMBG |
| 2025 | Role of LRP10 in Parkinson's disease and dementia: a knockout mouse model1R21AG094032-01 | XIONG, YULAN | UNIVERSITY OF CONNECTICUT SCH OF MED/DNT, CT | $457,875 | CDIN |
| 2025 | Non-invasive in-vivo BBB imaging: APOE4 and WM aging in US minority population1R21AG091815-01 | KOO, BANG-BONVACLAVU, LENA | BOSTON UNIVERSITY MEDICAL CAMPUS, MA | $452,561 | ZRG1 |
| 2025 | Reactive Astrogliosis and the Tripartite Synapse in Alzheimer's Disease1R21AG087072-01A1 | SERRANO-POZO, ALBERTO | MASSACHUSETTS GENERAL HOSPITAL, MA | $452,550 | CMBG |
| 2025 | Synthetic replicas of TDP-43 filaments associated with frontotemporal dementia1R21AG094047-01 | SUREWICZ, WITOLD K | CASE WESTERN RESERVE UNIVERSITY, OH | $442,750 | MSFB |
| 2025 | Digital detection of handwriting impairments in patients with atypical Alzheimer’s disease and frontotemporal dementia1R21AG093815-01 | MEADE, GABRIELAUTIANSKI, RENE LYNN | MAYO CLINIC ROCHESTER, MN | $441,100 | LCOM |
| 2025 | Antemortem biomarkers in nasally exhaled breath: A potential novel, noninvasive human diagnostic technique for Alzheimer’s Disease1R21AG091651-01 | ZELANO, CHRISTINA MARIA | NORTHWESTERN UNIVERSITY, IL | $440,000 | CNN |
| 2025 | Acetylation changes in alcoholic Alzheimer's disease mouse brains1R21AG091377-01A1 | KASUMOV, TAKHAR | NORTHEAST OHIO MEDICAL UNIVERSITY, OH | $439,865 | ZRG1 |
| 2025 | Decoding the Heterogeneity of Interneuron Vulnerability in Aging and Alzheimer's Disease: An Ultraplex CLEM Approach1R21AG096582-01 | KIRK, LYNDSEY M | UNIVERSITY OF TEXAS AT AUSTIN, TX | $438,625 | ITN |
| 2025 | Does extracellular tau modulate neurogenesis via LRP1?1R21AG096625-01 | HOPP, SARAH CHRISTINESAYRE, NAOMI LEDENE | UNIVERSITY OF TEXAS HLTH SCIENCE CENTER, TX | $433,125 | NCF |
| 2025 | Dissecting the neuroprotective role of an RNA binding protein in neurodegeneration1R21AG094078-01 | MAO, YINGWEI | PENNSYLVANIA STATE UNIVERSITY, THE, PA | $429,338 | ZRG1 |
| 2025 | The Role of Alzheimer's Disease Risk Genes in Neural Function, Degeneration, and Synapse Organization1R21AG091424-01 | MOSCA, TIMOTHY J. | THOMAS JEFFERSON UNIVERSITY, PA | $429,000 | NC |
| 2025 | Seeding activity of misfolded Abeta in eyes of Alzheimer's disease patients1R21AG080592-01A1 | MORALES, RODRIGO | UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON, TX | $429,000 | CMND |
| 2025 | Metal responsive transcription factors in neurodegeneration1R21AG087381-01A1 | VENKATACHALAM, KARTIK | UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON, TX | $429,000 | CMND |
| 2025 | Integrated micro-to-macro network models of disease spread in frontotemporal dementia1R21AG089706-01A1 | CHEN, MIN | UNIVERSITY OF PENNSYLVANIA, PA | $427,919 | ZRG1 |
| 2025 | Cascade Amplification Biosensor Technology for Detecting MicroRNA Biomarkers of Alzheimer Disease1R21AG089947-01A1 | VO-DINH, TUAN | DUKE UNIVERSITY, NC | $426,555 | EBIT |
| 2025 | Investigating how hippocampal place cell coding is affected by APOE4 homozygosity1R21AG096294-01 | COLGIN, LAURA L | UNIVERSITY OF TEXAS AT AUSTIN, TX | $425,986 | LMDN |
| 2025 | Systematic investigation of genetic contributions of sex chromosomes to Alzheimer's disease1R21AG091567-01 | WANG, QI | ARIZONA STATE UNIVERSITY-TEMPE CAMPUS, AZ | $425,501 | GHD |
| 2025 | Implementation Strategies for a Pharmacist-Led Community-Based Care Transition Program for Rural Older Adults with Dementia and their Care Partners1R21AG096566-01 | COE, ANTOINETTE BARTOLOTTA | UNIVERSITY OF MICHIGAN AT ANN ARBOR, MI | $422,319 | SIHH |
| 2025 | Reciprocal Interactions Linking Cognitive Performance, Aβ aggregation, and Transcriptional Processing with Sleep Disruption in an Alzheimer's Disease Model1R21AG096297-01 | DAVIS, CHRISTOPHER JOHNGERSTNER, JASON ROBERT | WASHINGTON STATE UNIVERSITY, WA | $420,750 | ZRG1 |
| 2025 | Understanding the Selective Mechanism of Tau Propagation in Alzheimer's Disease Through Multi-layer Spreading Pathways1R21AG091653-01A1 | WU, GUORONG RUDY | UNIV OF NORTH CAROLINA CHAPEL HILL, NC | $420,119 | MABS |
| 2025 | Can SARS-CoV-2 proteins accelerate Abeta pathology in fly and mouse models of AD?1R21AG091384-01 | RINCON-LIMAS, DIEGO E | UNIVERSITY OF FLORIDA, FL | $419,375 | CMND |
| 2025 | Pathological Implications of the tau-RNA Interaction1R21AG093972-01 | ABISAMBRA, JOSE FRANCISCOKOREN, JOHN | UNIVERSITY OF FLORIDA, FL | $419,375 | CMND |
| 2025 | Senescence induced by iron overload in the brain vasculature1R21AG091823-01A1 | MORUNO MANCHON, JOSE FELIX | UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON, TX | $417,800 | ZRG1 |
| 2025 | Adding Residential Address History Data to Project Talent: Unveiling the Long-Term Effects of Neighborhood Characteristics on Cognitive Risk and Resiliency1R21AG096259-01 | REDFORD, JEREMY | AMERICAN INSTITUTES FOR RESEARCH, VA | $417,296 | SSPA |
| 2025 | Cerebral Pulsatility as a Mechanism of Accelerated Cerebrovascular Aging across the Menopause Transition1R21AG089279-01A1 | LEFFERTS, WESLEY KUHN | IOWA STATE UNIVERSITY, IA | $405,155 | ASG |
| 2025 | The Medicaid Waiver Dataset Initiative: The Role of Medicaid Home- and Community-Based Services in Health and Health Care for Persons Living with Alzheimer's Disease and Related Dementias1R21AG089381-01A1 | MILLER, KATHERINE E. | JOHNS HOPKINS UNIVERSITY, MD | $405,049 | ZRG1 |
| 2025 | The combination of anti-amyloid therapy and rTMS for AD1R21AG091223-01A1 | MCNERNEY, MARGARET WINDY | PALO ALTO VETERANS INSTIT FOR RESEARCH, CA | $398,046 | ZRG1 |
| 2024 | Deciphering TDP-43 Proteinopathy: Unveiling the Consequences on Oligodendrocyte Dysfunction1R21AG087070-01 | PORTA ANTOLINEZ, SILVIA | UNIVERSITY OF PENNSYLVANIA, PA | $787,095 | CMND |
| 2024 | A Family-Based Macro-simulation Model on the Supply and Demand of Care for ADRD1R21AG083824-01A1 | WANG, JUE | RAND CORPORATION, CA | $539,635 | SSPA |
| 2024 | Exercise, Stress Biomarkers, and Alzheimer's Disease Neuropathology1R21AG087171-01 | OBERLIN, LAUREN ELIZABETH | ADVENTHEALTH ORLANDO, FL | $487,606 | MESH |
| 2024 | Development of an innovative Non-Invasive MR Imaging Technique for assessing Membrane Lipids and Their Properties in Alzheimer's Disease1R21AG089699-01 | ZU, ZHONGLIANG | VANDERBILT UNIVERSITY MEDICAL CENTER, TN | $481,250 | ZRG1 |
| 2024 | Implications of midlife alcohol use for risk of dementia in male and female twins: Unique contributions and interactions with APOE41R21AG087486-01 | LUCZAK, SUSAN E | UNIVERSITY OF SOUTHERN CALIFORNIA, CA | $468,534 | AIMR |
| 2024 | Architecture of Alzheimer's Disease1R21AG083965-01A1 | NEUMANN, ELIZABETH KATHLEEN | UNIVERSITY OF CALIFORNIA AT DAVIS, CA | $467,593 | ZRG1 |
| 2024 | Uncovering Dementia-Related Lipid Alterations and Mechanisms in Astrocytes1R21AG087400-01 | MCINTIRE, LAURA BETH JOHNSONORR, ANNA GOLDSHMIDT | WEILL MEDICAL COLL OF CORNELL UNIV, NY | $466,125 | CMBG |
| 2024 | Subcellular mito-nuclear balance and gene expression dynamics in Alzheimers's disease1R21AG091645-01 | CHURCHMAN, LEE STIRLING | HARVARD MEDICAL SCHOOL, MA | $466,125 | NOMD |
| 2024 | Developing new mouse models of andropause for ADRD research1R21AG089534-01 | ZULOAGA, KRISTEN LEANNE | ALBANY MEDICAL COLLEGE, NY | $462,923 | ZRG1 |
| 2024 | Investigating the Impact of Novel Senescent Microglia in Alzheimer's Disease Progression1R21AG087361-01 | YOUSEFZADEH, MATTHEW JZHU, YI | MAYO CLINIC ROCHESTER, MN | $461,058 | ZRG1 |
| 2024 | Identification of early markers for Alzheimer's disease by neuroimaging1R21AG091590-01 | GANGANNA, BASAVARAJU SANGANAHALLI | YALE UNIVERSITY, CT | $460,548 | NIC |
| 2024 | Potential of Dried Blood Spots for Measurement of Alzheimer's Disease Biomarkers1R21AG089842-01 | WEBB, PIA KIVISAKK | MASSACHUSETTS GENERAL HOSPITAL, MA | $459,250 | EBIT |
| 2024 | Identification of early transcriptional and pathological changes undergone by vulnerable brain regions during prodromal Alzheimer's disease1R21AG085464-01A1 | ROUSSARIE, JEAN-PIERRE | BOSTON UNIVERSITY MEDICAL CAMPUS, MA | $459,076 | ZRG1 |
| 2024 | Multimodal characterization of the mechanisms of selective vulnerability of entorhinal cortical neurons1R21AG084041-01A1 | LUEBKE, JENNIFER IROUSSARIE, JEAN-PIERRE | BOSTON UNIVERSITY MEDICAL CAMPUS, MA | $453,750 | MNG |
| 2024 | Aberrant PTEN signaling in chronically activated microglia drives tau pathology, neurodegeneration and cognitive decline following repetitive brain injury1R21AG087181-01 | OJO, JOSEPH O | ROSKAMP INSTITUTE, INC., FL | $449,460 | ZRG1 |
| 2024 | Nanotechnology for Glial Targeting and Inhibition of Neuroinflammation for Alzheimer’s Disease1R21AG085394-01 | GEBRIL, HODAMOGHE, PRABHAS VUHRICH, KATHRYN ELIZABETH | RUTGERS, THE STATE UNIV OF N.J., NJ | $445,625 | BNVT |
| 2024 | Does GLUT5-mediated Fructose Metabolism drive Microglial Dysfunction in Aging and Alzheimer's Disease?1R21AG091650-01 | BRUCE, KIMBERLEY DLANASPA GARCIA, MIGUEL ANGEL | UNIVERSITY OF COLORADO DENVER, CO | $442,104 | ZRG1 |
| 2024 | Influence of Sensory and Motor Dysfunctions on White - Gray Matters Functional Connectome in Preclinical AD1R21AG083915-01A1 | GAO, YURUI | VANDERBILT UNIVERSITY, TN | $438,448 | ZRG1 |
| 2024 | Voice Assistant to Provide Cognitive Stimulation Therapy at Scale1R21AG085439-01 | ABDULLAH, SAEED | PENNSYLVANIA STATE UNIVERSITY, THE, PA | $432,198 | ZRG1 |
| 2024 | A new diagnostic test for AD based on a neurotoxic Abeta Dimer1R21AG083776-01A1 | SCHEY, KEVIN LTRUSCOTT, ROGER J | VANDERBILT UNIVERSITY, TN | $431,826 | DMPB |
| 2024 | Dissecting the interaction between sex and APOE genotype in modulating AD risk1R21AG085470-01A1 | BRAFMAN, DAVID A | ARIZONA STATE UNIVERSITY-TEMPE CAMPUS, AZ | $431,750 | CMND |
| 2024 | Evaluating novel transcription factors in regulating astrocyte identity, reactivity, and their roles in neurodegenerative disease pathogenesis1R21AG089851-01 | MUSIEK, ERIK STEVENZHAO, GUOYAN | WASHINGTON UNIVERSITY, MO | $427,625 | CMBG |
| 2024 | Developing novel PET radioligands to image GPR39 in Alzheimer's Disease1R21AG089125-01 | SOLINGAPURAM SAI, KIRAN | WAKE FOREST UNIVERSITY HEALTH SCIENCES, NC | $426,250 | EITN |
| 2024 | Characterizing Spatial Variations in RNA Isoform Expression with Alzheimer's Disease1R21AG091356-01 | GREGORY, SIMON G | DUKE UNIVERSITY, NC | $423,994 | ZRG1 |
| 2024 | Changes in protein glycosylation due to translation of mannosidases encoded by circular RNAs1R21AG087332-01 | STAMM, STEFAN | UNIVERSITY OF KENTUCKY, KY | $420,750 | ZRG1 |
| 2024 | Biological Amyloids in the Mammalian Brain Extracellular Matrix1R21AG089761-01 | CORNWALL, GAIL A | TEXAS TECH UNIVERSITY HEALTH SCIS CENTER, TX | $420,750 | NDPR |
| 2024 | Deciphering genetics of PLCG2 alternative splicing to understand AD risk1R21AG083820-01A1 | ESTUS, STEVEN | UNIVERSITY OF KENTUCKY, KY | $415,626 | ZRG1 |
| 2024 | Cell type vulnerability to pathogenic tau accumulation in hippocampal CA11R21AG085555-01A1 | MCQUISTON, ADAM RORY | VIRGINIA COMMONWEALTH UNIVERSITY, VA | $408,638 | ZRG1 |
| 2024 | Robot-based Information and Support to Enhance Alzheimer's Caregiver Health (RISE)1R21AG087192-01 | ZHOU, WENJUN | UNIVERSITY OF TENNESSEE KNOXVILLE, TN | $401,090 | CMGC |
| 2024 | Mapping Brain Lipid Architecture in Aging, LBD and T Cell Therapy using novel Imaging Mass Spectrometry1R21AG089638-01 | PRENTICE, BOONE M.VEDAM-MAI, VINATA | UNIVERSITY OF FLORIDA, FL | $400,707 | CDIN |
| 2024 | mRNA localization as a driver of mitochondrial dysfunction during neurodegeneration1R21AG087396-01 | ZID, BRIAN MATTHEW | UNIVERSITY OF CALIFORNIA, SAN DIEGO, CA | $391,668 | NOMD |
| 2024 | A novel approach for targeting neuroinflammation in brain aging and Alzheimer's disease1R21AG085456-01 | LAROCCA, THOMAS | COLORADO STATE UNIVERSITY, CO | $281,962 | ZRG1 |
| 2024 | Super-Resolved Multimodal Imaging Biomarkers for Frontotemporal Dementia1R21AG087392-01 | DUTTA, JOYITASARANATHAN, MANOJKUMAR | UNIVERSITY OF MASSACHUSETTS AMHERST, MA | $268,730 | ZRG1 |
| 2024 | Evaluating the associations of hearing loss with cognitive and brain health outcomes in midlife1R21AG089427-01 | BRENOWITZ, WILLA DOMINO | KAISER FOUNDATION RESEARCH INSTITUTE, CA | $262,975 | AIMR |
| 2024 | The role of tetraspanin-regulated endolysosomal trafficking in Alzheimer's Disease1R21AG085486-01 | RICE, HEATHER C. | OKLAHOMA MEDICAL RESEARCH FOUNDATION, OK | $252,750 | CMND |
| 2024 | Linking NPTX2 and Tau pathophysiology in AD1R21AG085577-01 | ROH, SEUNG-EONWORLEY, PAUL F | JOHNS HOPKINS UNIVERSITY, MD | $249,047 | MNG |
| 2024 | Probing the heterogeneity of brain pericytes using new genetic tools1R21AG085559-01 | ZHAO, ZHEN | UNIVERSITY OF SOUTHERN CALIFORNIA, CA | $248,938 | CMBG |
| 2024 | A pulse-labeling assay to track extracellular vesicle spreading in the brain1R21AG085473-01 | WAITES, CLARISSA LEIGH | COLUMBIA UNIVERSITY HEALTH SCIENCES, NY | $246,750 | CDIN |
| 2024 | Improving Incontinence Support for Family Caregivers and Persons Living with Dementia1R21AG089658-01 | SUSKIND, ANNE M.YANK, VERONICA | UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA | $246,000 | CMGC |
| 2024 | Impaired cerebral metabolism and blood flow by neuronal and astrocytic dysfunctions in Alzheimer's disease1R21AG085366-01 | HERMAN, PETER | YALE UNIVERSITY, CT | $245,040 | ZRG1 |
| 2024 | Caregivers Preparing for Their Own Health Care Emergency1R21AG089840-01 | BOXER, REBECCA SUE | UNIVERSITY OF CALIFORNIA AT DAVIS, CA | $241,500 | CMGC |
| 2024 | Selective vulnerability and resilience to trans-synaptic pathological tau spreading in Alzheimers disease1R21AG089708-01 | TAGLIALATELA, GIULIO | UNIVERSITY OF TEXAS MED BR GALVESTON, TX | $240,000 | ZRG1 |
| 2024 | Understanding dynamics of brain network in TDP-43 related neurodegeneration1R21AG085492-01A1 | CHEN, RONG | UNIVERSITY OF MARYLAND BALTIMORE, MD | $238,968 | ZRG1 |
| 2024 | Investigating an African American-specific APOE genetic variant using hiPSC1R21AG085395-01A1 | BRAFMAN, DAVID A | ARIZONA STATE UNIVERSITY-TEMPE CAMPUS, AZ | $235,500 | ZRG1 |
| 2024 | Identify actionable drugs that enhance resilience in Alzheimer's disease individuals1R21AG087299-01 | DAI, YULINYU, LISHANZHAO, ZHONGMING | UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON, TX | $234,000 | ZRG1 |
| 2024 | Cellular senescence as a potential sex-specific driver of small vessel disease and post-stroke cognitive impairment in late adulthood1R21AG089655-01 | RITZEL, RODNEY | UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON, TX | $234,000 | ZRG1 |
| 2024 | Interrogating the protective effect of African APOE alleles on Alzheimer's disease risk through pleiotropy1R21AG089267-01 | BLUE, ELIZABETH ELOYCE | UNIVERSITY OF WASHINGTON, WA | $233,250 | AIMR |
| 2024 | Adaptation and feasibility testing of an AI-enabled web app based on acceptance and commitment therapy for family caregivers of people with dementia1R21AG085254-01A1 | HAN, AREUMLEE, HEE YUN | UNIVERSITY OF ALABAMA AT BIRMINGHAM, AL | $232,485 | CMGC |
| 2024 | Redirected CaMKII for restoring deficits in Alzheimer's disease models1R21AG083760-01A1 | PARK, JOONGKYU | WAYNE STATE UNIVERSITY, MI | $231,000 | ZRG1 |
| 2024 | Targeting age-related endosome dysfunction to treat cognitive decline and Alzheimer's disease1R21AG085586-01 | LARK, DANIELLAROCCA, THOMAS | COLORADO STATE UNIVERSITY, CO | $230,344 | ZRG1 |
| 2024 | Exploring Perivascular spaces in Alzheimer's disease using an automated Frangi filter technique1R21AG085605-01 | MEHTA, RASHI | WEST VIRGINIA UNIVERSITY, WV | $228,000 | CNN |
| 2024 | A Mouse Model for Braak I/II Alzheimer's Pathology1R21AG085588-01A1 | HUANG, ZHEN | UNIVERSITY OF WISCONSIN-MADISON, WI | $226,590 | ZRG1 |
| 2024 | Leveraging Consanguinity in Pakistan to Uncover the Genomic Architecture of Alzheimer's Disease: Feasibility Study with ENIGMA-PAK1R21AG085568-01A1 | ADAMSON, MAHEEN MAUSOOF | PALO ALTO VETERANS INSTIT FOR RESEARCH, CA | $223,902 | AIMR |
| 2024 | Distinguishing α-Synuclein S129 Phosphorylation in Health and Lewy Body Dementia1R21AG085401-01A1 | RAMALINGAM, NAGENDRAN | BRIGHAM AND WOMEN'S HOSPITAL, MA | $223,750 | CMND |
| 2024 | Reprogramming endothelial cells to prevent and treat Alzheimer disease (AD) and Hypertension1R21AG085331-01 | WENCESLAU, CAMILLA FERREIRA | UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA, SC | $223,500 | ZRG1 |
| 2024 | The Role of Cyclin C in mediating neurodegenerative proteinopathies1R21AG080666-01A1 | COOPER, KATRINA FRANCES | ROWAN UNIVERSITY SCHOOL/OSTEOPATHIC MED, NJ | $223,200 | CMAD |
| 2024 | Synaptic Resilience to Tau in Alzheimer's Disease1R21AG085379-01A1 | HERSKOWITZ, JEREMY H. | UNIVERSITY OF ALABAMA AT BIRMINGHAM, AL | $219,113 | ZRG1 |
| 2024 | Molecularly Dissecting How Obesity-Promoting Diets Activate the Neuronal Protein Aggregation Factor MOAG-4/SERF21R21AG085597-01A1 | O'ROURKE, EYLEEN JORGELINA | UNIVERSITY OF VIRGINIA, VA | $218,261 | NOMD |
| 2024 | Influence of microglial cell depletion and repopulation on aducanumab induced ARIA and vascular lesions in APOE4 carriers with AD1R21AG089503-01 | OJO, JOSEPH O | ROSKAMP INSTITUTE, INC., FL | $213,125 | ZRG1 |
| 2024 | Submillimeter resolution diffusion MRI of the medial temporal lobe in the earliest stages of Alzheimer's disease1R21AG082377-01A1 | BILGIC, BERKINHUANG, SUSIE YI | MASSACHUSETTS GENERAL HOSPITAL, MA | $208,750 | ZRG1 |
| 2024 | Multiplex meningeal lymphatic activation for Alzheimer’s disease1R21AG089268-01 | CHEN, JIANFU | UNIVERSITY OF SOUTHERN CALIFORNIA, CA | $207,500 | ZRG1 |
| 2024 | Modulating blood flow and metabolism in Alzheimer's Disease models1R21AG085655-01 | YASEEN, MOHAMMAD ABBAS | NORTHEASTERN UNIVERSITY, MA | $200,000 | ZRG1 |
| 2024 | NOX2 Small Molecule Inhibitors as a Therapeutic Strategy in the Treatment of Alzheimer’s Disease1R21AG089718-01 | PAGANO, PATRICK JVAZQUEZ, ALBERTO L | UNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA | $198,750 | ZRG1 |
| 2024 | Impact of SARS-Cov-2 on a Rat Model Cerebral Amyloid Angiopathy1R21AG089374-01 | VAN NOSTRAND, WILLIAM E. | UNIVERSITY OF RHODE ISLAND, RI | $196,875 | ZRG1 |
| 2024 | Illuminating early microglial dysfunction in Alzheimer's disease through integration of explainable AI and iPSC models1R21AG089394-01 | JAYADEV, SUMANLEE, SU-IN | UNIVERSITY OF WASHINGTON, WA | $191,891 | ZRG1 |
| 2024 | Assessing Neuronal Vulnerability in the Entorhinal Cortex due to Alzheimer's Disease Pathology1R21AG089715-01 | HUSSAINI, S. ABID | COLUMBIA UNIVERSITY HEALTH SCIENCES, NY | $73,582 | CDIN |
| 2023 | The role of CDK6 in Alzheimer's Disease1R21AG078484-01A1 | HU, MIAOFEN G | TUFTS MEDICAL CENTER, MA | $489,500 | ZRG1 |
| 2023 | Targeting the ANG/TIE2 pathway to treat Alzheimer's disease and related dementias1R21AG083891-01 | HOWELL, GARETH R | JACKSON LABORATORY, ME | $480,536 | ZRG1 |
| 2023 | Development of novel polysomnography-based digital biomarkers to predict Alzheimer’s disease and Parkinson’s disease in real world settings1R21AG085495-01 | LENG, YUE | UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA | $469,214 | NMBH |
| 2023 | Nanobodies targeting stress granule components1R21AG083761-01 | CHO, YONGKU PETER | UNIVERSITY OF CONNECTICUT STORRS, CT | $460,800 | CMND |
| 2023 | Cerebrovascular contributions to APOE4-mediated brain bioenergetic deficits in Alzheimer's disease1R21AG080375-01A1 | ABDULLAH, LAILA | ROSKAMP INSTITUTE, INC., FL | $449,460 | NOMD |
| 2023 | The role of PPARγ in astrocyte pathobiology after exposure to repetitive mild traumatic brain injury1R21AG080661-01A1 | OJO, JOSEPH O | ROSKAMP INSTITUTE, INC., FL | $449,444 | CMBG |
| 2023 | Over-The-Counter Hearing Aid Treatment For Adults With Cognitive Decline Due To Alzheimer's Disease And Related Dementias1R21AG083928-01 | SOUZA, PAMELA E. | NORTHWESTERN UNIVERSITY, IL | $443,758 | LCOM |
| 2023 | Identifying diagnostic biomarkers for Delirium and predicting cognitive Outcomes in hospitalized older adults using automated Speech Analysis (IDOSA)1R21AG082054-01A1 | SINVANI, LIRON DANAYTANG, SUNNY XIAOJING | FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH, NY | $439,232 | APDA |
| 2023 | Rates of brain acetylome remodeling in a mouse model of diabetes and tauopathy1R21AG085590-01 | KASUMOV, TAKHAR | NORTHEAST OHIO MEDICAL UNIVERSITY, OH | $429,000 | CMND |
| 2023 | Inference by interference: Task-dependent pupil responses as an early detection method for Alzheimer's disease related brainstem functional change1R21AG082214-01A1 | RIPHAGEN, JOOST | MASSACHUSETTS GENERAL HOSPITAL, MA | $426,353 | CNN |
| 2023 | Mitochondrial dysfunction and tau pathology in Alzheimer's disease1R21AG085324-01 | JOHNSON, GAIL V. W.WOJTOVICH, ANDREW PHILLIP | UNIVERSITY OF ROCHESTER, NY | $423,500 | NOMD |
| 2023 | Investigating Genomic Instability and Loss of the Y Chromosome in Alzheimer’s Disease1R21AG079196-01A1 | CUKIER, HOLLY NGRISWOLD, ANTHONY JOHN | UNIVERSITY OF MIAMI SCHOOL OF MEDICINE, FL | $422,125 | MNG |
| 2023 | DNA methylation signatures of Alzheimer's disease in aged astrocytes1R21AG085428-01 | CARLESS, MELANIE | UNIVERSITY OF TEXAS SAN ANTONIO, TX | $410,290 | CMBG |
| 2023 | A novel therapeutic approach for Alzheimer Disease (AD)1R21AG080715-01A1 | DING, SHINGHUA | UNIVERSITY OF MISSOURI-COLUMBIA, MO | $392,026 | NOMD |
| 2023 | Functions of Tau protein in human neural cells1R21AG079161-01A1 | YOUNG, JESSICA ELAINE | UNIVERSITY OF WASHINGTON, WA | $269,875 | CMND |
| 2023 | Anastasis in age-related neurodegeneration1R21AG080713-01 | FEANY, MEL B | BRIGHAM AND WOMEN'S HOSPITAL, MA | $268,500 | NOMD |
| 2023 | Targeting the alpha secretase ADAM10 for the treatment of Alzheimer's disease1R21AG080685-01 | NIKOLOV, DIMITAR B | SLOAN-KETTERING INST CAN RESEARCH, NY | $265,500 | MSFB |
| 2023 | Neuromodulation of brain network function in preclinical and prodromal Alzheimer's Disease1R21AG080588-01 | DICKERSON, BRADFORD CTOUROUTOGLOU, ALEXANDRA | MASSACHUSETTS GENERAL HOSPITAL, MA | $252,000 | ZRG1 |
| 2023 | Dissecting connections between diet, the microbiome and Alzheimers disease1R21AG084042-01 | TISSENBAUM, HEIDI A | UNIV OF MASSACHUSETTS MED SCH WORCESTER, MA | $251,250 | ZRG1 |
| 2023 | Contribution of HUWE1 to sex differences in aging and Alzheimer's disease1R21AG083962-01 | JUNG, SUNG YUNTSVETKOV, ANDREY | UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON, TX | $249,995 | ZRG1 |
| 2023 | Immunomodulatory and behavioral effects of CAR T regulatory cell therapy for Alzheimer's Disease”.1R21AG081632-01 | SENTMAN, CHARLES L. | DARTMOUTH COLLEGE, NH | $246,000 | ZRG1 |
| 2023 | Resolving the genetic interaction between DAB1 and APOE4 in Alzheimer's.1R21AG080800-01 | HOWELL, BRIAN W. | UPSTATE MEDICAL UNIVERSITY, NY | $244,500 | CMND |
| 2023 | Brain capillary Piezo1 ion channels and blood flow regulation in Alzheimer’s Disease1R21AG082193-01 | BRACKO, OLIVERHARRAZ, OSAMA F | UNIVERSITY OF MIAMI CORAL GABLES, FL | $242,093 | ZRG1 |
| 2023 | Eph and Lyn hyper-phosphorylation and CRMP interactions in AD"1R21AG084065-01 | BUCK, MATTHIAS | CASE WESTERN RESERVE UNIVERSITY, OH | $241,500 | MSFB |
| 2023 | Does Vision Loss Affect Tauopathy in the Brain1R21AG082389-01 | XIA, FANZHANG, WENBO | UNIVERSITY OF TEXAS MED BR GALVESTON, TX | $240,000 | CDIN |
| 2023 | Combining electron and nuclear magnetic resonance to track Alzheimer's amyloid-beta oligomer-to-fibril conversion1R21AG082041-01 | GUO, ZHEFENGPARAVASTU, ANANT KRISHNA | UNIVERSITY OF CALIFORNIA LOS ANGELES, CA | $238,776 | MSFB |
| 2023 | The contribution of Ly6h to Alzheimers Disease1R21AG080788-01 | JOINER, WILLIAM J | UNIVERSITY OF CALIFORNIA, SAN DIEGO, CA | $237,000 | CDIN |
| 2023 | A novel non-transgenic fly model for tauopathies1R21AG082324-01 | KUO, MIN-HAO | MICHIGAN STATE UNIVERSITY, MI | $234,750 | CMND |
| 2023 | Innovative precision medicine methods in subgroup identification for Alzheimer's disease1R21AG084054-01 | LIU, LEIWANG, GUOQIAO | WASHINGTON UNIVERSITY, MO | $233,250 | CDMA |
| 2023 | Helping Behaviors and Cognitive Functioning in Later Life: Linkages with Genetic Risks for Alzheimer's Disease and Disadvantaged Neighborhood Socioeconomic Status1R21AG079122-01A1 | HAN, SAE HWANG | UNIVERSITY OF TEXAS AT AUSTIN, TX | $231,126 | LHB |
| 2023 | Role of human apolipoprotein E isoforms in long-term effects of West Nile Virus exposure on Alzheimer's disease-related behavioral alteration, cognitive injury, neuroinflammation, and neuropathology1R21AG079158-01A1 | HIRSCH, ALEC JRABER, JACOB | OREGON HEALTH & SCIENCE UNIVERSITY, OR | $231,000 | ZRG1 |
| 2023 | Insights into Amyloid Pathogenicity Dynamics1R21AG080705-01 | HANRIEDER, JORGSAVAS, JEFFREY NICHOLAS | NORTHWESTERN UNIVERSITY AT CHICAGO, IL | $230,940 | CDIN |
| 2023 | Drug repurposing for Alzheimer’s disease-related inflammation caused by a TBI1R21AG077495-01A1 | BACHSTETTER, ADAM DGENSEL, JOHN C | UNIVERSITY OF KENTUCKY, KY | $229,500 | ZRG1 |
| 2023 | Olfactory Epithelium Responses to Human APOE Alleles1R21AG082081-01 | MCCLINTOCK, TIMOTHY S | UNIVERSITY OF KENTUCKY, KY | $229,500 | NIC |
| 2023 | Deep learning for prediction of Mild Cognitive Impairment and Dementia of the Alzheimer's type1R21AG082204-01 | LIU, ZHONGMINGPELTIER, SCOTT JAMES | UNIVERSITY OF MICHIGAN AT ANN ARBOR, MI | $224,509 | ASG |
| 2023 | Influence of swallowing impairment on burden among caregivers of persons with Alzheimer's Disease and related dementias1R21AG082326-01 | SHUNE, SAMANTHA EVE | UNIVERSITY OF OREGON, OR | $224,188 | CMGC |
| 2023 | Specificity of ABCA7-mediated lipid efflux and its effects on intracellular lipid metabolism in neural cells1R21AG080729-01 | LYSSENKO, NICHOLAS | TEMPLE UNIV OF THE COMMONWEALTH, PA | $223,217 | BBM |
| 2023 | Targeting P2RX7 Signaling as a Biomarker for ADRD1R21AG083791-01 | MEYER, JASON STEPHENONOS, KRISTEN DIANESCHULTE, MICHAEL LTERRITO, PAUL RICHARD | INDIANA UNIVERSITY INDIANAPOLIS, IN | $222,816 | ZRG1 |
| 2023 | Lifespan extension, Somatotropic signaling and Tauopathy1R21AG082327-01 | SUN, LIOU | UNIVERSITY OF ALABAMA AT BIRMINGHAM, AL | $222,750 | ZRG1 |
| 2023 | Time restricted eating for prevention of age-related vascular cognitive decline in older adults1R21AG080775-01A1 | TARANTINI, STEFANOYABLUCHANSKIY, ANDRIY | UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR, OK | $217,500 | ASG |
| 2023 | How women’s reproductive life-history relates to cognitive decline and neuropathology in Alzheimer’s disease and related dementias1R21AG079093-01A1 | FOX, MOLLY MAURER | UNIVERSITY OF CALIFORNIA LOS ANGELES, CA | $217,191 | ASG |
| 2023 | Variability and Volume of Day-to-Day Lifestyle Activity in Sustaining Cognitive Function among Insufficiently Active Older Adults at Risk for Alzheimer's Disease and Related Dementias1R21AG077515-01A1 | YANG, CHIH-HSIANG | UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA, SC | $216,836 | LCBH |
| 2023 | Home Alone: Developing a Home-Based Intervention for People with Cognitive Impairment Who Live Alone1R21AG080744-01 | GAUGLER, JOSEPH E. | UNIVERSITY OF MINNESOTA, MN | $204,541 | LCBH |
| 2023 | Glucose Variability as a Digital Biomarker for Preclinical AD Risk in Prediabetes.1R21AG077647-01A1 | KHAMBATY, TASNEEM | UNIVERSITY OF MARYLAND BALTIMORE COUNTY, MD | $199,700 | APDA |
| 2023 | Deep Learning for Detecting the Early Anatomical Effects of Alzheimer's Disease1R21AG082082-01 | FISCHL, BRUCE | MASSACHUSETTS GENERAL HOSPITAL, MA | $198,700 | EITN |
| 2023 | Molecular analysis of SORL1 function and dysfunction in Alzheimer's disease1R21AG082333-01 | LI, LIAN | EMORY UNIVERSITY, GA | $195,625 | ZRG1 |
| 2023 | Reverse electron transport and tauopathy1R21AG083863-01 | LU, BINGWEI | STANFORD UNIVERSITY, CA | $193,637 | NOMD |
| 2023 | Sleep, breathing, hemodynamic oscillations, and cerebrospinal fluid movements - Building toward a novel treatment approach for Alzheimer's disease1R21AG077461-01A1 | SCHWICHTENBERG, AMY JTONG, YUNJIE | PURDUE UNIVERSITY, IN | $190,026 | CNN |
| 2023 | Infectious history as a determinant of age-related inflammation in Alzheimers disease1R21AG082156-01 | KAECH, SUSAN M | SALK INSTITUTE FOR BIOLOGICAL STUDIES, CA | $190,000 | ZRG1 |
| 2023 | The predicative values of vascular and metabolic disorders for risk of incident mild cognitive impairment and dementia1R21AG082210-01 | LIU, LONGJIAN | DREXEL UNIVERSITY, PA | $189,588 | ZRG1 |
| 2023 | Saliva based protein markers for predicting the risk of cognitive decline and dementia in older adults.1R21AG082164-01 | JAIN, SHALINI | UNIVERSITY OF SOUTH FLORIDA, FL | $187,448 | ASG |
| 2023 | Discovery and validation of biomarkers of autoimmunity in Alzheimer's Disease.1R21AG080575-01 | DIAMANDIS, ELEFTHERIOS P | SINAI HEALTH SYSTEM, ON | $138,240 | ZRG1 |
| 2023 | Epidemiology and Clinical Outcomes of Electroconvulsive Therapy Use in Nursing Home Residents with Dementia1R21AG078972-01A1 | RHEE, TAEHO GREGORY | UNIVERSITY OF CONNECTICUT SCH OF MED/DNT, CT | $137,676 | HSQE |
| 2023 | Improving Quality of Care for Persons with Dementia in Nursing Homes – Evaluation of the National Background Check Program1R21AG082047-01 | SHARMA, HARI | UNIVERSITY OF IOWA, IA | $133,854 | ODHS |
Data: Grants.gov's daily extract and NIH's notice pages and award files, in ScienceGraph release conductgrants-2026-11-09-0.1.0. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.