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NIH funding notice PAR-22-102

Investigational New Drug (IND)-enabling and Early-Stage Development of Medications to Treat Alcohol Use disorder and Alcohol-Associated Organ Damage (U43/U44 Clinical Trial Optional)

Closed on December 4, 2024.

Posted
January 21, 2022
Close date
December 4, 2024
Activity codes
Not stated on the notice page
Institutes taking part
Not stated on the notice page

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

Its page was not saved, so the notices it replaced are not known.

Who won it before

6 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $5,372,931 in first-year total cost, median $986,666.

Most frequent study sections

  1. Special Emphasis Panel[ZAA1 GG (44)]5
  2. Special Emphasis Panel[ZAA1 DD (44)]1

Most frequent institutions

  1. AFASCI, INC.1
  2. AMYGDALA NEUROSCIENCES, INC.1
  3. CAMINO PHARMA, LLC1
  4. DEMERX, INC.1
  5. KULEON LLC1
Competing awards under PAR-22-102 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2025Novel and functionally selective 5-HT2C receptor agonist for treating Alcohol Use Disorder1U43AA032128-01FOREST, JEREMYKULEON LLC, WA$1,001,425ZAA1
2025Investigational New Drug (IND)-enabling Study for a New Therapeutic for Alcohol Use Disorder (AUD)1U43AA032129-01LLOYD, LINDA SSTRESS THERAPEUTICS, INC., CA$999,393ZAA1
2025Investigational New Drug Development of Noribogaine for Alcohol Use Disorder1R43AA032127-01KRAMER, E DOUGLASMASH, DEBORAH C.DEMERX, INC., FL$914,324ZAA1
2023Investigational New Drug (IND)-enabling and Early-Stage Development of Selective, Reversible, Orally Bioavailable ALDH2 inhibitor ANS-00858 to Treat Alcohol Use Disorder.1U43AA030689-01A1BLACKBURN, BRENT KEITHAMYGDALA NEUROSCIENCES, INC., CA$1,000,000ZAA1
2023Preclinical validation of mGlu2 PAMs in alcohol use disorder1U43AA031388-01GADIENT, RETO ANDREASGOULD, ROBERT WARRENSHEFFLER, DOUGLAS JCAMINO PHARMA, LLC, CA$973,938ZAA1
2023Development of a Novel Medication for Alcohol Use Disorder with an Active IND Dual Inhibitor of T-Type Calcium Channel and Soluble Epoxide Hydrolase1U43AA031391-01XIE, XINMIN SIMONYE, JIANG-HONGAFASCI, INC., CA$483,851ZAA1

Data: Grants.gov's daily extract and NIH's notice pages and award files, in ScienceGraph release conductgrants-2026-11-09-0.1.0. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.

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