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NIH funding notice PAR-23-059

National Cancer Institute Program Project Applications for the Years 2023, 2024, and 2025 (P01 Clinical Trial Optional)

Closed on May 26, 2026.

Posted
December 14, 2022
Close date
May 26, 2026
Activity codes
Not stated on the notice page
Institutes taking part
Not stated on the notice page

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

Its page was not saved, so the notices it replaced are not known.

Who won it before

32 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $80,873,466 in first-year total cost, median $2,470,716.

Most frequent study sections

  1. Special Emphasis Panel[ZCA1 RPRB-T (M1)]8
  2. Special Emphasis Panel[ZCA1 RPRB-M (J1)]4
  3. Special Emphasis Panel[ZCA1 RPRB-T (J1)]4
  4. Special Emphasis Panel[ZCA1 RPRB-H (J1)]2
  5. Special Emphasis Panel[ZCA1 RPRB-H (O1)]2

Most frequent institutions

  1. UNIVERSITY OF TX MD ANDERSON CAN CTR3
  2. DANA-FARBER CANCER INST2
  3. NEW YORK UNIVERSITY SCHOOL OF MEDICINE2
  4. UNIVERSITY OF CALIFORNIA, SAN FRANCISCO2
  5. UNIVERSITY OF TEXAS HLTH SCIENCE CENTER2
Competing awards under PAR-23-059 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2025Fusion oncoprotein condensates in pediatric cancers1P01CA298963-01KRIWACKI, RICHARD WMULLIGHAN, CHARLES GST. JUDE CHILDREN'S RESEARCH HOSPITAL, TN$3,032,826ZCA1
2025Immunobiology and Immune Therapy for Merkel Cell Carcinoma2P01CA225517-06A1NGHIEM, PAULUNIVERSITY OF WASHINGTON, WA$2,994,993ZCA1
2025Bone Marrow Grafting and Cellular Therapy for Leukemia and Lymphoma2P01CA049605-34A1MIKLOS, DAVID B.NEGRIN, ROBERT SSTANFORD UNIVERSITY, CA$2,936,016ZCA1
2025Advancing Hormone Therapy for Endometrial Cancer1P01CA278735-01A1GERTZ, JASONLESLIE, KIMBERLY K.UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR, NM$2,801,881ZCA1
2025Mutant p53 in Tumorigenesis, Invasion, and Metastasis1P01CA291694-01A1MANFREDI, JAMES JICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY$2,679,816ZCA1
2025Ceramide-Directed Therapeutics for Treatment of AML1P01CA302570-01CHALFANT, CHARLES E.LOUGHRAN, THOMAS P.UNIVERSITY OF VIRGINIA, VA$2,663,053ZCA1
2025The Molecular Drivers and Therapeutic Susceptibilities in Lineage State Transitions of Metastatic Prostate Cancer1P01CA298991-01LANG, JOSHUAUNIVERSITY OF WISCONSIN-MADISON, WI$2,579,971ZCA1
2025Lipid Metabolism as a Determinant of Ferroptosis Sensitivity in Cancer1P01CA291697-01A1JIANG, XUEJUNSLOAN-KETTERING INST CAN RESEARCH, NY$2,489,032ZCA1
2025Convergent Epigenetic Control of Neuroendocrine Cancers1P01CA295524-01DECAPRIO, JAMES A.DANA-FARBER CANCER INST, MA$2,452,400ZCA1
2025Polymerase theta, genome instability, and cancer2P01CA247773-06RAMSDEN, DALE AUNIV OF NORTH CAROLINA CHAPEL HILL, NC$2,440,899ZCA1
2025InHANCE: Imaging Innovation for Head And Neck Cancer Evaluation & Treatment Delivery1P01CA278716-01A1BROCK, KRISTYFULLER, CLIFTON DAVIDHUTCHESON, KATHERINE ARNOLDLAI, STEPHEN YUNIVERSITY OF TX MD ANDERSON CAN CTR, TX$2,392,505ZCA1
2025The impact of changes in chromatin architecture on cancer phenotypes and tumor progression2P01CA229086-06A1SKOK, JANE AMANDANEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY$2,304,725ZCA1
2025Sphingolipids in Cancer Biology and Therapy2P01CA097132-21A1HANNUN, YUSUF AWNISTATE UNIVERSITY NEW YORK STONY BROOK, NY$2,208,375ZCA1
2025Tipping Points in Cancer1P01CA288662-01A1LANDER, ARTHUR DLAWSON, DEVON A.LOWENGRUB, JOHNUNIVERSITY OF CALIFORNIA-IRVINE, CA$2,186,372ZCA1
2025Mechanisms of Bladder Cancer Development and Its Therapeutic Vulnerabilities to Preventive and Interventive Therapy.1P01CA296429-01A1CZERNIAK, BOGDAN AMCCONKEY, DAVID J.UNIVERSITY OF TX MD ANDERSON CAN CTR, TX$2,108,734ZCA1
2025Development of Novel Therapeutic Strategies in Human Leukemias2P01CA066996-26ARMSTRONG, SCOTT AEBERT, BENJAMIN LEVINEDANA-FARBER CANCER INST, MA$2,052,164ZCA1
2025APOBEC Mutagenesis in Cancer2P01CA234228-06A1HARRIS, REUBEN SYEE, DOUGLASUNIVERSITY OF TEXAS HLTH SCIENCE CENTER, TX$2,002,938ZCA1
2025Androgen Receptor Action in Castration Resistant Prostate Cancer2P01CA163227-11A1BALK, STEVEN P.BETH ISRAEL DEACONESS MEDICAL CENTER, MA$1,990,456ZCA1
2025Retrovirus Models of Cancer2P01CA100730-21RATNER, LEEWASHINGTON UNIVERSITY, MO$1,971,061ZCA1
2025Discovery of Anticancer Agents of Diverse Natural Origin2P01CA125066-16FUCHS, JAMES RKINGHORN, ALAN DOUGLASOBERLIES, NICHOLAS H.OHIO STATE UNIVERSITY, OH$1,640,056ZCA1
2024Adult Leukemia Research Center2P01CA018029-48A1HILL, GEOFFREY ROGERFRED HUTCHINSON CANCER CENTER, WA$4,359,202ZCA1
2024WISDOM: A platform to optimize subtype-specific screening and prevention1P01CA281826-01A1ESSERMAN, LAURA JVAN'T VEER, LAURA JUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$3,537,456ZCA1
2024Targetable epigenetic and transcriptional mechanisms in melanoma thatshape the microenvironment2P01CA163222-11FISHER, DAVID EMASSACHUSETTS GENERAL HOSPITAL, MA$2,800,993ZCA1
2024Aging-related hematopoietic stem cell intrinsic and microenvironmental signals in AML transformation1P01CA285250-01A1KOUSTENI, STAVROULACOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$2,775,137ZCA1
2024ExpLoiting thErapeutic VulnerAbilities in hepaTocEllular carcinoma (ELEVATE)1P01CA275740-01A1SARKAR, DEVANANDVIRGINIA COMMONWEALTH UNIVERSITY, VA$2,678,459ZCA1
2024Imaging and Genomic Signatures of Brain Tumor Heterogeneity and Evolution to Optimize Patient Management2P01CA118816-16CHANG, SUSAN MLUPO, JANINE MARIEVIGNERON, DANIEL BUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$2,654,906ZCA1
2024Epigenetic basis and therapeutic targeting of the unique lymphoma immunological niche1P01CA272295-01A1CERCHIETTI, LEANDRO CFLOWERS, CHRISTOPHER RWEILL MEDICAL COLL OF CORNELL UNIV, NY$2,561,215ZCA1
2024Regulation of BRCA-dependent Genome Repair via the 53BP1 Axis1P01CA275717-01A1SUNG, PATRICKUNIVERSITY OF TEXAS HLTH SCIENCE CENTER, TX$2,556,071ZCA1
2024OPC SURVIVOR: Optimizing OroPharyngeal Cancer SURVIVORship1P01CA285249-01A1FULLER, CLIFTON DAVIDHUTCHESON, KATHERINE ARNOLDLAI, STEPHEN YUNIVERSITY OF TX MD ANDERSON CAN CTR, TX$2,447,812ZCA1
2024Role of hypernutrition and metabolic stress in non-alcoholic steatohepatitis (NASH) driven hepatocellular carcinoma (HCC)1P01CA281819-01A1KAUFMAN, RANDAL J.SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE, CA$2,397,277ZCA1
2024Understanding Integration in Oncology Care and Association with Quality and Outcomes1P01CA281850-01A1KEATING, NANCY LLANDRUM, MARY BETHHARVARD MEDICAL SCHOOL, MA$2,282,687ZCA1
2024Investigating and Targeting Replication Stress in Small Cell Lung Cancer1P01CA288368-01HUANG, TONY TUNGPOIRIER, JOHN THOMASNEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY$1,893,978ZCA1

Data: Grants.gov's daily extract and NIH's notice pages and award files, in ScienceGraph release conductgrants-2026-11-09-0.1.0. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.

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