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NIH funding notice PAR-23-081

Early and Late Stage Clinical Trials for the Spectrum of Alzheimers Disease/Alzheimers Related Dementias and Age-Related Cognitive Decline (R01 Clinical Trial Optional)

Closed on November 6, 2024.

Posted
December 23, 2022
Close date
November 6, 2024
Activity codes
Not stated on the notice page
Institutes taking part
Not stated on the notice page

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

Its page was not saved, so the notices it replaced are not known.

Who won it before

15 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $43,615,062 in first-year total cost, median $1,167,871.

Most frequent study sections

  1. Aging Systems and Geriatrics Study Section[ASG]3
  2. Adult Psychopathology and Disorders of Aging Study Section[APDA]2
  3. Clinical Neuroscience and Neurodegeneration Study Section[CNN]2
  4. Analytics and Statistics for Population Research Panel A Study Section[ASPA]1
  5. Clinical Neurodegeneration Translational Neuroscience Study Section[CNTN]1

Most frequent institutions

  1. BANNER HEALTH1
  2. BOSTON UNIVERSITY (CHARLES RIVER CAMPUS)1
  3. COLUMBIA UNIVERSITY HEALTH SCIENCES1
  4. HEBREW REHABILITATION CENTER FOR AGED1
  5. INDIANA UNIVERSITY INDIANAPOLIS1
Competing awards under PAR-23-081 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2025Investigating the Benefits of Remotely-supervised Neuromodulation in Primary Progressive Aphasia1RF1AG085565-01A1HENRY, MAYARICHARDSON, JESSICA DUNIVERSITY OF TEXAS AT AUSTIN, TX$5,343,452ZRG1
2025FDA approved IND 29644: Multicenter Phase 1 Trial to Evaluate Safety and Immunogenicity of Preventive Tau Vaccine, AV-1980R/A, in cognitively unimpaired preclinical AD participants.1R01AG092949-01AGADJANYAN, MICHAEL GGALVIN, JAMES ESCHNEIDER, LON STOSUN-TURGUT, DUYGUINSTITUTE FOR MOLECULAR MEDICINE, CA$5,308,961CNTN
2025Network-based neuromodulation for posterior cortical atrophy1RF1AG093689-01A1HAMPSTEAD, BENJAMIN MICHAELUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$3,664,645CDBA
2025Real-world and Innovative Multimodal Prediction and Prevention of Postoperative Mortality and Multi-morbidity1R01AG085115-01A1MAHAJAN, AMANSADHASIVAM, SENTHILKUMARUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$801,268ZRG1
2025Rescuing Visual Perception in Aging Adults by Restructuring the Alpha-Gamma Neural Code1R01AG090379-01A1REINHART, ROBERTBOSTON UNIVERSITY (CHARLES RIVER CAMPUS), MA$343,350HCMF
2024The Progressive Supranuclear Palsy Clinical Trial Platform (PTP)1R01AG085029-01BOXER, ADAM L.LITVAN, IRENEROJAS-MARTINEZ, JULIO CESARWILLS, ANNE-MARIEUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$15,782,145ZRG1
2024Alzheimer's Prevention Initiative ADAD Colombia Trial Program1R01AG086363-01ALEXANDER, ROBERT CLANGBAUM, JESSICA BROOKEQUIROZ, YAKEEL T.REIMAN, ERIC MICHAELBANNER HEALTH, AZ$4,541,398CNN
2024COGNITIVE TRAINING AND NEUROPLASTICITY IN MILD COGNITIVE IMPAIRMENT2R01AG052440-06A1DEVANAND, DAVANGERE PCOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$1,813,346APDA
2024MAEVE: Microbiota mediated flavonoid metabolites for cognitive health1R01AG081768-01A1CHURCH, ARPANAMAYER, EMERAN AUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$1,563,756ASG
2024Long-term home-based transcranial electrical stimulation for cognitive and motor function in older adults with an increased risk of dementia: a randomized controlled trial1R01AG081349-01A1HAUSDORFF, JEFFREY MMANOR, BRADLEY D.HEBREW REHABILITATION CENTER FOR AGED, MA$1,167,871ZRG1
2024ADEPT-ICU: Attenuating Depression with Internet Cognitive Behavioral Therapy (CBT) to Slow Cognitive Decline in Older Intensive Care Unit (ICU) Survivors1R01AG084754-01A1KHAN, BABAR ASTEWART, JESSE CWANG, SOPHIAINDIANA UNIVERSITY INDIANAPOLIS, IN$795,205APDA
2024Optimizing CNS DHA delivery in elderly adults at risk for dementia1R01AG084834-01A1KRIKORIAN, ROBERTMCNAMARA, ROBERT K.UNIVERSITY OF CINCINNATI, OH$784,995ASG
2024Phase I Cell Therapy for Maintaining Cholinergic Circuits in the Spectrum of Alzheimer’s Disease1R01AG081356-01A1GERHARDT, GREG A.QUINTERO, JORGE ESLEVIN, JOHN T.VAN HORNE, CRAIGUNIVERSITY OF KENTUCKY, KY$659,568CNN
2024Age-related Cognitive Changes: Effects of Combined Flavonoid Intake and Physical Exertion Mediated by the Gut Microbiome1R01AG084660-01A1CHEATHAM, CAROL LLILA, MARY ANN ANNNIEMAN, DAVID CHRISTOPHERNORTH CAROLINA STATE UNIVERSITY RALEIGH, NC$573,170ASG
2024Statistical methods to characterize patients who highly benefit across multifaceted clinical outcomes, from treatments in Alzheimers Disease and Related Dementias (ADRD)1R01AG083423-01A1FRANGAKIS, CONSTANTINE EJOHNS HOPKINS UNIVERSITY, MD$471,932ASPA

Data: Grants.gov's daily extract and NIH's notice pages and award files, in ScienceGraph release conductgrants-2026-11-09-0.1.0. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.

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PAR-23-081: Early and Late Stage Clinical Trials for the Spectrum of Alzheimers Disease/Alzheimers Related Dementias and Age-Related Cognitive Decline (R01 Clinical Trial Optional) | ScienceDex | ConductScience