The notices it replaced
Its page was not saved, so the notices it replaced are not known.
Who won it before
470 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $236,212,260 in first-year total cost, median $391,988.
Most frequent study sections
- Maximizing Investigators' Research Award - E Study Section[MRAE]67
- Maximizing Investigators' Research Award - D Study Section[MRAD]51
- Maximizing Investigators' Research Award - F Study Section[MRAF]51
- Special Emphasis Panel[ZRG1 MBBC-F (55)]48
- Maximizing Investigators' Research Award C Study Section[MRAC]45
Most frequent institutions
- UNIVERSITY OF PENNSYLVANIA11
- UNIVERSITY OF MICHIGAN AT ANN ARBOR10
- UNIVERSITY OF FLORIDA9
- UNIVERSITY OF WISCONSIN-MADISON9
- CORNELL UNIVERSITY8
| FY | Project | PIs | Institution | First-year cost | Study section |
|---|---|---|---|---|---|
| 2025 | Developing and Discovering Covalent Inhibitors through Fragmentation-First Experimentation1R35GM159997-01 | BLAIR, DANIEL JAMES | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, TN | $2,503,299 | MRAE |
| 2025 | Decoding the Molecular Choreography of Diverse Vesicle Release Mechanisms1R35GM160124-01 | RAMAKRISHNAN, SATHISH K | YALE UNIVERSITY, CT | $2,313,209 | MRAB |
| 2025 | Protein aggregation controlled by disaggregases.1R35GM160152-01 | SEIDLER, PAUL MATTHEW | UNIVERSITY OF SOUTHERN CALIFORNIA, CA | $2,282,500 | MRAB |
| 2025 | Mechanisms of cell fate specification by glycosylation1R35GM160483-01 | KASPER, DIONNA | DARTMOUTH COLLEGE, NH | $2,252,479 | ZRG1 |
| 2025 | Phylodynamics of Cell Populations1R35GM160119-01 | HOEHN, KENNETH | DARTMOUTH COLLEGE, NH | $2,252,479 | MRAF |
| 2025 | Catalytic Mechanism, Regulation and Drug-Target Potential of Bacterial Alarmone Hydrolases1R35GM160160-01 | WANG, BOYUAN | UT SOUTHWESTERN MEDICAL CENTER, TX | $2,233,277 | MRAE |
| 2025 | Understanding the Metabolic Regulation of Immune Responses to Bacterial Infections1R35GM160393-01 | WONG FOK LUNG, TANIA | RUTGERS BIOMEDICAL AND HEALTH SCIENCES, NJ | $2,158,750 | ZRG1 |
| 2025 | Mechanisms regulating inflammatory fibroblasts in wound healing1R35GM160121-01 | ABEBAYEHU, DANIEL | UNIVERSITY OF VIRGINIA, VA | $2,157,780 | ZRG1 |
| 2025 | Rhythms of Resistance: Unraveling the impact of natural circadian variation on immunity1R35GM159944-01 | MANSFELD, BEN N. | WASHINGTON UNIVERSITY, MO | $2,138,125 | MRAD |
| 2025 | Investigating the impact of RNA structural dynamics on function of the lncRNA FIRRE1R35GM160278-01 | JONES, ALISHA | NEW YORK UNIVERSITY, NY | $2,129,028 | MRAE |
| 2025 | Xenobiotic induction mechanisms affecting pharmacokinetics and pharmacodynamics among medically complex children, adolescents, and young adults.1R35GM160200-01 | CONSTANCE, JONATHAN ERIC | UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH, UT | $2,117,500 | ZRG1 |
| 2025 | Regulation of selenium metabolism and stress response1R35GM159998-01 | LI, ZHIPENG | UNIVERSITY OF FLORIDA, FL | $2,110,625 | MRAC |
| 2025 | Biological role and pharmacology of EXPERA family proteins and their effect onsterol homeostasis1R35GM160280-01 | ALON, ASSAF | YALE UNIVERSITY, CT | $2,102,917 | MRAE |
| 2025 | Response of the commensal microbiota to host physiological stress1R35GM159868-01 | PETRULLO, LAUREN | UNIVERSITY OF ARIZONA, AZ | $2,095,736 | ZRG1 |
| 2025 | The crossroads between the methionine cycle and the coronavirus RNA capping.1R35GM159976-01 | ROSAS LEMUS, MONICA | UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR, NM | $2,094,250 | MRAB |
| 2025 | Deciphering the cellular origins and impact of toxic formaldehyde in mammalian cells1R35GM160077-01 | WANG, MENG | CORNELL UNIVERSITY, NY | $2,070,575 | MRAC |
| 2025 | Early detection and inference for emerging infectious agents in data-sparse settings1R35GM156799-01 | PEI, SEN | COLUMBIA UNIVERSITY HEALTH SCIENCES, NY | $2,056,250 | ZRG1 |
| 2025 | Robust Multivariate Methods for Analyzing Pathway Interactions and Pathway-Phenotype Associations in Bulk and Single-Cell RNA-seq Studies1R35GM159674-01 | WANG, YUE | UNIVERSITY OF COLORADO DENVER, CO | $2,053,480 | MRAA |
| 2025 | Decoding the Neural Foundations of Sexual Dimorphisms in Aggression: A Female-Centric Approach1R35GM157195-01 | PALAVICINO-MAGGIO, CAROLINE | MCLEAN HOSPITAL, MA | $2,050,000 | ZRG1 |
| 2025 | Dissect Human Primordial Germ Cell Development Using Stem Cell Models1R35GM159918-01 | ZHENG, YI | SYRACUSE UNIVERSITY, NY | $2,043,430 | ZRG1 |
| 2025 | Single molecule dissection of Arp2/3 complex activity and regulators in living cells1R35GM160127-01 | TANG, QING | UNIVERSITY OF NEBRASKA LINCOLN, NE | $2,041,875 | MRAD |
| 2025 | Development of Haloperoxidase Enzymes for New Applications in Chemical Synthesis1R35GM160291-01 | BIEGASIEWICZ, KYLE FRANCIS | EMORY UNIVERSITY, GA | $2,021,315 | MRAE |
| 2025 | Probing the Effects of Pathological Conditions on AKT1R35GM159958-01 | MARSIGLIA, WILLIAM M | UNIVERSITY OF ALABAMA AT BIRMINGHAM, AL | $2,011,691 | MRAE |
| 2025 | Enzyme-Inspired Multimetallic Cooperativity: Leveraging Metal Pairing Effects for Heightened Reactivity1R35GM159848-01 | BUSS, JOSHUA A | UNIVERSITY OF MICHIGAN AT ANN ARBOR, MI | $2,011,480 | MRAB |
| 2025 | Investigating local protein co-translational folding in situ with high spatiotemporal resolution1R35GM160021-01 | ZHAO, NING | UNIVERSITY OF COLORADO DENVER, CO | $1,998,288 | MRAE |
| 2025 | Directing and Deciphering Macrophage Polarization through Biologically-Inspired Surface Design of Polymer Brush-Coated Cell Culture Substrates1R35GM160484-01 | KUMAR, RAMYA | COLORADO SCHOOL OF MINES, CO | $1,993,748 | ZRG1 |
| 2025 | Regulation of the mitotic DNA damage response1R35GM160196-01 | KRAIS, JOHN | WASHINGTON UNIVERSITY, MO | $1,943,750 | MRAF |
| 2025 | Structural dynamics of the human mitochondrial pyruvate carrier associated with transport and inhibition1R35GM159817-01 | MCCOMMIS, KYLE S | SAINT LOUIS UNIVERSITY, MO | $1,925,000 | MRAB |
| 2025 | Defining microbial metabolic interactions in polymicrobial environments1R35GM160019-01 | IBBERSON, CAROLYN BROOK | UNIVERSITY OF TENNESSEE KNOXVILLE, TN | $1,921,875 | MRAF |
| 2025 | DNA Protein Cross-Links: Metabolic Sources and Repair1R35GM159935-01 | ERBER, LUKE | UNIVERSITY OF KANSAS LAWRENCE, KS | $1,843,775 | MRAE |
| 2025 | Redefining Nanomedicine Beyond One-Size-Fits-All: Uncovering Mechanisms of Sex Differences and Female Life Stages in Drug Delivery1R35GM160475-01 | LANIER, OLIVIA LAUREN | UNIVERSITY OF NEW MEXICO, NM | $1,833,094 | ZRG1 |
| 2025 | A continuous evolution platform for cyclic peptide discovery1R35GM159851-01 | WANG, TINA | UNIVERSITY OF WISCONSIN-MADISON, WI | $1,827,200 | MRAB |
| 2025 | Revealing the Molecular Basis of Microtubule-Intermediate Filament Interactions.1R35GM160317-01 | WALTON, TRAVIS | VAN ANDEL RESEARCH INSTITUTE, MI | $528,000 | MRAD |
| 2025 | Elucidating chromatin structure and function of double minutes through cell cycles1R35GM160211-01 | DAO, HAI | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, TN | $508,750 | MRAF |
| 2025 | Understanding the Platelet-CD8+ T Cell Interactions in Sepsis1R35GM160360-01 | GUO, LI | BLOODWORKS, WA | $504,644 | MRAC |
| 2025 | Developing a Multi-Organ Multi-Omics Computational Framework for StudyingMammalian Iron Systems Biology1R35GM160386-01 | AGORO, RAFIOU | JACKSON LABORATORY, ME | $486,750 | MRAD |
| 2025 | Defining mechanisms that underlie well-controlled translation initiation1R35GM160398-01 | LAPOINTE, CHRISTOPHER PAUL | FRED HUTCHINSON CANCER CENTER, WA | $484,000 | MRAE |
| 2025 | Mapping and Prediction of Epistatic Enhancer Interactions in Gene Regulation1R35GM160316-01 | LIN, XUEQIU | FRED HUTCHINSON CANCER CENTER, WA | $484,000 | MRAF |
| 2025 | Mechanisms of epithelial tube development, orientation and integrity1R35GM159833-01 | PERILLO, MARGHERITA | MARINE BIOLOGICAL LABORATORY, MA | $471,625 | MRAC |
| 2025 | Regulation of gene transcription and DNA replication by chromatin readers from the BET family1R35GM160259-01 | DONCZEW, RAFAL | OKLAHOMA MEDICAL RESEARCH FOUNDATION, OK | $468,875 | MRAF |
| 2025 | Peptide-receptor signaling in plant-microbe interactions1R35GM160060-01 | MUELLER, LENA MARIA | SALK INSTITUTE FOR BIOLOGICAL STUDIES, CA | $468,750 | ZRG1 |
| 2025 | Decoding RNA Localization and Local Translation: Key Mechanisms of Cellular Adaption and Function1R35GM159898-01 | HACISULEYMAN, EZGI | UNIVERSITY OF FLORIDA, FL | $466,125 | MRAC |
| 2025 | High Throughput Lipidomic Profiling with High Structural Specificity for Phenotypic Screening1R35GM156826-01 | ZHENG, XUEYUN | BATTELLE PACIFIC NORTHWEST LABORATORIES, WA | $465,197 | MRAE |
| 2025 | Advancing Sepsis Biology and Care Through the Power of Modern Biobanks1R35GM160530-01 | ASGARI, SAMIRA | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY | $462,981 | MRAD |
| 2025 | Deciphering the genetic regulation of bacterial heterogeneity in response to antibiotic stress using single-cell transcriptomics1R35GM157243-01 | MA, PEIJUN | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, TN | $462,500 | ZRG1 |
| 2025 | A New Mode of Inhibition to Target Protein-Protein Interactions by Ligand-Transferred Oxidation1R35GM160115-01 | MAIANTI, JUAN PABLO | ALBERT EINSTEIN COLLEGE OF MEDICINE, NY | $462,000 | MRAE |
| 2025 | Minimax entropy: Optimal statistical models for neural activity and chromatin structure1R35GM160188-01 | LYNN, CHRISTOPHER | YALE UNIVERSITY, CT | $460,740 | ZRG1 |
| 2025 | Dissecting continuous phenotypic transitions in cellular states with novel quantitative experimental and computational methods1R35GM160070-01 | CHUNG, HATTIE | YALE UNIVERSITY, CT | $460,740 | MRAF |
| 2025 | Decoding cis-regulatory element activity through deep learning frameworks1R35GM160300-01 | MOORE, JILL ELIZABETH | UNIV OF MASSACHUSETTS MED SCH WORCESTER, MA | $460,625 | MRAF |
| 2025 | Modeling Aneuploidy-Driven Phenotypes Across Tissues1R35GM160085-01 | WATSON, EMMA V. | UNIV OF MASSACHUSETTS MED SCH WORCESTER, MA | $460,625 | MRAF |
| 2025 | Causal inference of common and personalized single-cell gene regulatory networks1R35GM160536-01 | WANG, LINGFEI | UNIV OF MASSACHUSETTS MED SCH WORCESTER, MA | $460,625 | MRAA |
| 2025 | Systematic understanding of RNA-centric mechanisms of gene regulation in chromatin1R35GM160013-01 | HWANG, TAEYOUNG | LIEBER INSTITUTE, INC., MD | $459,250 | MRAA |
| 2025 | Structurally Decoding the Biosynthetic Logic of Modular Polyketide Synthases1R35GM160153-01 | COGAN, DILLON P | UNIVERSITY OF SOUTHERN CALIFORNIA, CA | $456,500 | MRAE |
| 2025 | Suspect Treat Organ failure Prevent Sepsis Mortality (STOP Sepsis Mortality)1R35GM157142-01 | KOUTROULIS, IOANNIS | CHILDREN'S RESEARCH INSTITUTE, DC | $455,000 | MRAD |
| 2025 | Role of Circadian Rhythms and Sleep Disorders in Perioperative Neurocognitive Disorders Trajectories1R35GM159961-01 | VACAS, SUSANA | MASSACHUSETTS GENERAL HOSPITAL, MA | $453,750 | MRAD |
| 2025 | Metabolic Control of Membrane Lysis1R35GM159938-01 | EVAVOLD, CHARLES LEE | MASSACHUSETTS GENERAL HOSPITAL, MA | $453,750 | MRAD |
| 2025 | Harnessing Sleep and Biological Rhythms to Improve Postoperative Recovery1R35GM160254-01 | GAO, LEI | MASSACHUSETTS GENERAL HOSPITAL, MA | $453,750 | MRAD |
| 2025 | Metabolic control of extracellular matrix synthesis1R35GM160032-01 | SCHWÖRER, SIMON | UNIVERSITY OF CHICAGO, IL | $451,000 | MRAC |
| 2025 | Statistical methods to delineate the spatial and temporal pattern of cell-cell interactions in Spatial Transcriptomics data1R35GM159819-01 | LI, ZIYI | UNIVERSITY OF TX MD ANDERSON CAN CTR, TX | $449,625 | ZRG1 |
| 2025 | Measuring and modeling gene expression trajectories: new computational-experimental approaches1R35GM160123-01 | CLEARY, BRIAN LOWMAN | BOSTON UNIVERSITY (CHARLES RIVER CAMPUS), MA | $449,625 | MRAA |
| 2025 | Developing sulfonium lipid nanoparticles as a novel platform for mRNA delivery1R35GM160083-01 | LI, YAMIN | UPSTATE MEDICAL UNIVERSITY, NY | $448,250 | ZRG1 |
| 2025 | Deciphering novel cell death mechanisms and metabolic reprogramming in response to microenvironmental stress.1R35GM159930-01 | ELLEBRECHT, CHRISTOPH THOMAS | UNIVERSITY OF PENNSYLVANIA, PA | $446,875 | MRAD |
| 2025 | Molecular mechanisms of DNA double strand break repair by homologous recombination1R35GM157235-01 | STINSON, BENJAMIN M | DANA-FARBER CANCER INST, MA | $445,000 | ZRG1 |
| 2025 | Unraveling the Mechanisms of Protein Sorting and Localization to Organelles1R35GM160490-01 | JOMAA, AHMAD | UNIVERSITY OF VIRGINIA, VA | $444,125 | MRAE |
| 2025 | Geometrical Regulation of Collective Cellular Responses in Three-Dimensional Space and Time1R35GM160480-01 | ABACI, HASAN ERBIL | COLUMBIA UNIVERSITY HEALTH SCIENCES, NY | $443,878 | ZRG1 |
| 2025 | Role of nitrate in microbiota ecology1R35GM160210-01 | STACY, APOLLO | CLEVELAND CLINIC LERNER COM-CWRU, OH | $442,750 | ZRG1 |
| 2025 | Regulation of canonical and non-canonical substrates of histone lysine methyltransferases1R35GM160046-01 | YU, JIA-RAY | VIRGINIA POLYTECHNIC INST AND ST UNIV, VA | $442,750 | MRAF |
| 2025 | Understanding the role of anesthesia in perioperative organ injury via wireless soft implants1R35GM159840-01 | OUYANG, WEI | DARTMOUTH COLLEGE, NH | $441,626 | ZRG1 |
| 2025 | Regulation of translation initiation by the epitranscriptome1R35GM159598-01 | ARANGO, DANIEL | NORTHWESTERN UNIVERSITY, IL | $440,000 | MRAF |
| 2025 | Deciphering Mechanosignaling Using Multi-fluorescence Biomembrane Force Probe1R35GM159909-01 | CHEN, YUNFENG | UNIVERSITY OF TEXAS MED BR GALVESTON, TX | $440,000 | ZRG1 |
| 2025 | Deciphering The Role of RNA Modifications In Maternal Mrna Clearance1R35GM159853-01 | BRACHOVA, PAVLA | OLD DOMINION UNIVERSITY, VA | $440,000 | MRAA |
| 2025 | Advanced computational approaches for single-cell multi-omics integration1R35GM159862-01 | LIU, SHUCHANG SILVIA | UNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA | $437,250 | MRAA |
| 2025 | Improving Characterization of Individualized Treatment Effects in Critical Illness1R35GM160146-01 | SHAH, FARAAZ ALI | UNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA | $437,250 | MRAD |
| 2025 | Coding and Noncoding Molecular Mechanisms of a Bifunctional Gene in Multiple Cellular Contexts1R35GM160270-01 | PELTIER, DANIEL C. | INDIANA UNIVERSITY INDIANAPOLIS, IN | $435,875 | ZRG1 |
| 2025 | Nuclear Envelope Dynamics in Meiotic Quality Control1R35GM160292-01 | LIU, CHENSHU | LEHIGH UNIVERSITY, PA | $434,679 | MRAC |
| 2025 | Designing a Comprehensive Machine Learning-driven Prescriptive Clinical Decision Support System for Shock and Associated Critical Care Conditions1R35GM159939-01 | YOON, JOO HEUNG | UNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA | $433,710 | MRAD |
| 2025 | Multidisciplinary approach to studying genomic variation on genome function and phenotype1R35GM159831-01 | SOBREIRA, DEBORA RODRIGUES | UNIVERSITY OF CALIFORNIA LOS ANGELES, CA | $433,125 | MRAA |
| 2025 | Molecular consequences of microtubule bending in living cells1R35GM159972-01 | NIHONGAKI, YUTA | OHIO STATE UNIVERSITY, OH | $433,125 | MRAC |
| 2025 | Deciphering the role of sex hormones in host-microbiome interactions in the human oral mucosa1R35GM160617-01 | GHEZZI, CHIARA | UNIVERSITY OF MASSACHUSETTS LOWELL, MA | $433,125 | ZRG1 |
| 2025 | Harnessing the Power of Data and Artificial Intelligence to Resolve the Human 3D Interactome1R35GM160468-01 | CONG, QIAN | UT SOUTHWESTERN MEDICAL CENTER, TX | $431,800 | MRAE |
| 2025 | Impact of ecological interactions on mutant fitness and evolution in microbes1R35GM160220-01 | MANHART, MICHAEL | RUTGERS BIOMEDICAL AND HEALTH SCIENCES, NJ | $431,750 | MRAA |
| 2025 | Hypertensive Toads: Investigating the Physiological and Evolutionary Pathways to Salt Tolerance in Amphibians1R35GM160308-01 | ALBECKER, MOLLY | UNIVERSITY OF HOUSTON, TX | $431,750 | MRAA |
| 2025 | Enhancing our understanding of intercellular communication to achieve programmable regeneration1R35GM160552-01 | FRANK, MARGARET | CORNELL UNIVERSITY, NY | $431,750 | MRAC |
| 2025 | Elucidating the function of ribonucleoprotein condensates in living cells1R35GM160207-01 | WU, JIAHUI | UNIVERSITY OF MASSACHUSETTS AMHERST, MA | $431,656 | MRAE |
| 2025 | Probing spatiotemporal mechanobiology through novel dynamic material platforms1R35GM160045-01 | CORBIN, ELISE ANNE | UNIVERSITY OF DELAWARE, DE | $430,675 | ZRG1 |
| 2025 | Molecular Mechanisms Drive Metabolic and Lipid Profiles that Define Cells in the Latent and Lytic Stages of Viral Infection1R35GM160182-01 | SANCHEZ, ERICA LEE | UNIVERSITY OF TEXAS DALLAS, TX | $429,000 | ZRG1 |
| 2025 | Clarifying engineered bioabsorbable metals tissue-biomaterial interface and regeneration1R35GM160342-01 | GUILLORY, ROGER J. | MEDICAL COLLEGE OF WISCONSIN, WI | $429,000 | ZRG1 |
| 2025 | Investigation of how RNA-directed feedback loops coordinate wound healing and regeneration1R35GM160161-01 | OSBORNE, JIHAN K. | UT SOUTHWESTERN MEDICAL CENTER, TX | $428,600 | ZRG1 |
| 2025 | Precise GI Drug Delivery and Modeling with Pharmacomicrobiomics1R35GM159916-01 | CAO, SHIJIE | UNIVERSITY OF WASHINGTON, WA | $427,625 | ZRG1 |
| 2025 | Capillaric microfluidics for integrated, self-powered, and self-regulated sample preparation in miniaturized mass spectrometry systems1R35GM159828-01 | OLANREWAJU, AYOKUNLE OLUWAFEMI | UNIVERSITY OF WASHINGTON, WA | $427,625 | ZRG1 |
| 2025 | Molecular mechanisms of compound microtubule structure and function1R35GM160185-01 | WANG, JENNIFER TONG | WASHINGTON UNIVERSITY, MO | $427,625 | MRAC |
| 2025 | Towards precision risk stratification, diagnosis, and treatment: statistical and computational machinery for synthesizing information across massive, diverse sources of genomic and clinical data1R35GM160458-01 | NISHIMURA, AKIHIKO | JOHNS HOPKINS UNIVERSITY, MD | $426,479 | ZRG1 |
| 2025 | Novel pathways in heterochromatin regulation1R35GM154839-01 | KIRKLAND, JACOB GORDON | OKLAHOMA MEDICAL RESEARCH FOUNDATION, OK | $426,250 | MRAF |
| 2025 | Novel regulation of fibrinogen expression and function1R35GM160266-01 | POOLE, LAUREN G | RUTGERS BIOMEDICAL AND HEALTH SCIENCES, NJ | $425,302 | MRAC |
| 2025 | Discovery and application of halogenases for medicinal chemistry1R35GM159745-01 | LUKOWSKI, APRIL | UNIVERSITY OF CALIFORNIA, SAN DIEGO, CA | $423,975 | MRAB |
| 2025 | Deconstructing the Genetic Basis of Complex Trait Variation1R35GM157134-01 | MOSTAFAVI, HAKHAMANESH | NEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY | $423,750 | MRAF |
| 2025 | Integrative Computational Models for Decoding Disease Mechanisms and Predicting Drug Synergies in Spatial Transcriptomics1R35GM160372-01 | MA, YING | BROWN UNIVERSITY, RI | $423,616 | ZRG1 |
| 2025 | Somatic mosaicism across mouse tissues during different life stages1R35GM159832-01 | ZHANG, LEI | UNIVERSITY OF MINNESOTA, MN | $423,500 | MRAA |
| 2025 | Mechanisms of compartmentalized signaling in electrically excitable cells1R35GM160566-01 | VIERRA, NICHOLAS CATIN | UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH, UT | $423,500 | MRAC |
| 2025 | Novel Burn Sepsis Prognostic Strategies: Deciphering Early Immune Progenitor Shifts in Burn Sepsis Development and Modulation of Host Burn Response through Angiopoietin-Tie Signaling1R35GM160273-01 | KUBASIAK, JOHN | LOYOLA UNIVERSITY CHICAGO, IL | $423,500 | MRAD |
| 2025 | Advancing Free Energy Methods for Drug Design1R35GM159878-01 | DING, XINQIANG | TUFTS UNIVERSITY MEDFORD, MA | $422,958 | MRAB |
| 2025 | Mechanisms and functions of lipid recycling for cellular metabolism1R35GM156863-01 | CHUNG, JEEYUN | HARVARD UNIVERSITY, MA | $422,500 | MRAD |
| 2025 | Myeloid-Derived Suppressor Cells in Immunological Endotyping and Intervention of Chronic Critical Illness after Sepsis1R35GM160352-01 | CAI, GUOSHUAI | UNIVERSITY OF FLORIDA, FL | $422,125 | MRAD |
| 2025 | Decoding Enzyme Sequence-Activity Relationships via Generative AI for Rational Enzyme Design1R35GM159995-01 | XIE, WENJUN | UNIVERSITY OF FLORIDA, FL | $422,125 | MRAB |
| 2025 | Deciphering and predicting ecologically sensitive gut microbiome contributions to human metabolic health1R35GM160067-01 | CARMODY, RACHEL NAOMI | HARVARD UNIVERSITY, MA | $421,250 | ZRG1 |
| 2025 | Viral Biosensors of Host Post-Translational Modifications1R35GM160071-01 | BOUHADDOU, MEHDI | UNIVERSITY OF CALIFORNIA LOS ANGELES, CA | $420,984 | MRAE |
| 2025 | Statistical Approaches to Unlock Protein Function from Deep Mutational Scans1R35GM160065-01 | PIMENTEL, HAROLD | UNIVERSITY OF CALIFORNIA LOS ANGELES, CA | $420,984 | ZRG1 |
| 2025 | Investigating the Mechanisms of Brain-Heart Communication Under Stress1R35GM160031-01 | RAJBHANDARI, ABHA KARKI | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY | $420,834 | MRAC |
| 2025 | Exploiting microbial regulatory networks to accelerate natural products discovery1R35GM159915-01 | PEREIRA, FILIPA | UNIVERSITY OF MICHIGAN AT ANN ARBOR, MI | $420,066 | MRAB |
| 2025 | Molecular Mechanisms of Stress-Induced Mitochondrial Damage1R35GM156982-01 | NEGINSKAYA, MARIA A | ALBERT EINSTEIN COLLEGE OF MEDICINE, NY | $420,000 | ZRG1 |
| 2025 | T Cell Receptor Mediated T Cell Activation in Neonatal and Pediatric Sepsis1R35GM157197-01 | TAYLOR, MATTHEW DAVID | FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH, NY | $418,750 | MRAD |
| 2025 | Linking Conformational Dynamics to Activity Impairment of Disease-associated Human Enzymes1R35GM160337-01 | ZHU, WEN | FLORIDA STATE UNIVERSITY, FL | $417,498 | MRAB |
| 2025 | Mechanisms of Bacterial Lysis Sensing1R35GM160020-01 | BRIDGES, ANDREW A. | CARNEGIE-MELLON UNIVERSITY, PA | $417,450 | MRAF |
| 2025 | Mechanisms and Regulations of Neutral Lipid Metabolism1R35GM160171-01 | SUI, XUEWU | TEXAS A&M AGRILIFE RESEARCH, TX | $416,398 | MRAE |
| 2025 | Defining the Role of Matrix-Bound Nanovesicles in Extracellular Matrix Formation and Wound Repair1R35GM160216-01 | DEWEY, MARLEY JOHNSTONE | UNIVERSITY OF CALIFORNIA SANTA BARBARA, CA | $415,662 | ZRG1 |
| 2025 | Differential stress responses of organelles to nutritional versus ER stress1R35GM159748-01 | WANG, NING | UNIVERSITY OF ROCHESTER, NY | $414,159 | MRAD |
| 2025 | Leveraging diverse ancestry and environmental variables to understand the evolution and architecture of complex traits1R35GM160467-01 | DURVASULA, ARUN | UNIVERSITY OF SOUTHERN CALIFORNIA, CA | $413,300 | MRAA |
| 2025 | Biocatalytic synthesis of complex medicinal small molecules informed by A.I. planning1R35GM160499-01 | SANKARANARAYANAN, KARTHIK | PURDUE UNIVERSITY, IN | $412,632 | MRAE |
| 2025 | Integrating frequency and phenotypic association data to improve interpretation of rare genetic variants1R35GM157035-01 | KARCZEWSKI, KONRAD | MASSACHUSETTS GENERAL HOSPITAL, MA | $412,500 | ZRG1 |
| 2025 | Investigating stem and progenitor cell quality assurance in development andregeneration.1R35GM159855-01 | WATTRUS, SAMUEL | MASSACHUSETTS GENERAL HOSPITAL, MA | $412,500 | ZRG1 |
| 2025 | Sequence transformations and microbiology: theory, tools, & discovery1R35GM160134-01 | YU, YUN WILLIAM | CARNEGIE-MELLON UNIVERSITY, PA | $412,295 | MRAA |
| 2025 | Controlling drug crystallization, polymorphism, and physicochemical properties using mechanochemistry1R35GM160214-01 | HUTCHINS, KRISTIN MARIE | UNIVERSITY OF MISSOURI-COLUMBIA, MO | $411,454 | MRAE |
| 2025 | Dissecting the molecular composition and function of contact between membrane-bound and membrane-less organelles1R35GM157319-01 | LIAO, YA-CHENG | COLUMBIA UNIVERSITY HEALTH SCIENCES, NY | $411,250 | MRAF |
| 2025 | Molecular Mechanisms Underlying TRPM3 Regulation in the Cell Membrane1R35GM160009-01 | ZHAO, CHEN | UNIVERSITY OF FLORIDA, FL | $410,601 | MRAB |
| 2025 | Generative multiscale models of biomolecular conformational dynamics: from fluctuations to many-component assemblies1R35GM159834-01 | ROTSKOFF, GRANT | STANFORD UNIVERSITY, CA | $410,256 | MRAE |
| 2025 | Evolutionary Diversification of Cytoskeletal Proteins for Tissue-Specialized Roles1R35GM156807-01 | SCHROEDER, COURTNEY MEGAN | UT SOUTHWESTERN MEDICAL CENTER, TX | $410,000 | ZRG1 |
| 2025 | In situ investigation of bacterial secretion systems using cryo-electron tomography1R35GM157116-01 | KAPLAN, MOHAMMED | UNIVERSITY OF CHICAGO, IL | $410,000 | MRAB |
| 2025 | Scalable and Epidemiologically Interpretable Phylodynamics to Recover Heterogeneous Transmission Dynamics1R35GM160163-01 | MUELLER, NICOLA FELIX | UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA | $410,000 | ZRG1 |
| 2025 | Harnessing Nanoscale Presentation to Elucidate the Impact of Therapeutic Packaging on Innate Immunity1R35GM157326-01 | TEPLENSKY, MICHELLE H | BOSTON UNIVERSITY (CHARLES RIVER CAMPUS), MA | $408,750 | ZRG1 |
| 2025 | Investigating and Utilizing Microbial Appendages1R35GM159704-01 | WANG, FENGBIN | UNIVERSITY OF ALABAMA AT BIRMINGHAM, AL | $408,375 | MRAE |
| 2025 | Uncovering the rules governing mobile genetic element spread1R35GM160469-01 | WEISBERG, ALEXANDRA J | OREGON STATE UNIVERSITY, OR | $408,375 | MRAA |
| 2025 | Molecular mechanisms of lysosome remodeling in response to cellular stress1R35GM159962-01 | YANG, XI | UNIVERSITY OF DENVER (COLORADO SEMINARY), CO | $407,562 | MRAD |
| 2025 | Regulation of SNARE-mediated autophagosome-lysosome fusion by accessory proteins1R35GM160081-01 | COURTNEY, KEVIN C | WEST VIRGINIA UNIVERSITY, WV | $407,044 | MRAD |
| 2025 | Targeting Membrane Environments: The Role of Oleate Hydratase (OhyA) in Lipid-Protein Interactions Across Microbial Communities1R35GM159612-01 | RADKA, CHRISTOPHER DAVID | UNIVERSITY OF KENTUCKY, KY | $406,652 | MRAB |
| 2025 | Immuno-mechanical regulation of monocytes in fibrotic niches1R35GM157079-01 | VINING, KYLE HOLMBERG | UNIVERSITY OF PENNSYLVANIA, PA | $406,250 | ZRG1 |
| 2025 | Implementing the nascent ECM into the dynamic reciprocity of cell-ECM interactions1R35GM157063-01 | LOEBEL, CLAUDIA | UNIVERSITY OF PENNSYLVANIA, PA | $406,250 | ZRG1 |
| 2025 | Novel Molecules as a Window to Anesthetic Mechanisms1R35GM156838-01 | WHITE, ELIZABETH RAILEY | UNIVERSITY OF PENNSYLVANIA, PA | $406,250 | MRAE |
| 2025 | Statistical methods and tools for enhancing polygenic risk prediction and discovery of causal gene pathways1R35GM157133-01 | JIN, JIN | UNIVERSITY OF PENNSYLVANIA, PA | $406,250 | MRAF |
| 2025 | How cell maturation is regulated by circadian and metabolic rhythms1R35GM157320-01 | ALVAREZ, JUAN R | UNIVERSITY OF PENNSYLVANIA, PA | $406,250 | MRAD |
| 2025 | Advancing Disease Modeling through Mathematical Frameworks: Leveraging Single-Cell Spatial Data to Uncover Tissue-Specific Pathways and Immune Responses1R35GM159993-01 | SHAHRIYARI, LEILI | UNIVERSITY OF MASSACHUSETTS AMHERST, MA | $406,250 | ZRG1 |
| 2025 | Z-DNA and its role in RNA polymerase III transcriptional regulation1R35GM159821-01 | GROW, EDWARD J | UT SOUTHWESTERN MEDICAL CENTER, TX | $404,569 | MRAA |
| 2025 | Single-molecule imaging and mechanisms of crossover regulation on meiotic chromosomes1R35GM159985-01 | VON DIEZMANN, LEXY | UNIVERSITY OF MINNESOTA, MN | $404,058 | MRAC |
| 2025 | Unraveling effects of gut and blood microbial signatures on immune phenotypes and organ dysfunction in sepsis1R35GM156920-01 | SERBANESCU, MARA ALEXANDRA | DUKE UNIVERSITY, NC | $403,750 | MRAD |
| 2025 | Synthetic biology tools and strategies to streamline the sensing and responding to disease cues in engineered theragnostic bacteria.1R35GM156762-01 | DWIDAR, MOHAMMED | CLEVELAND CLINIC LERNER COM-CWRU, OH | $402,500 | ZRG1 |
| 2025 | Heme-Based Immune Dysregulation in Critical Illness1R35GM160336-01 | REMY, KENNETH EUGENE | CASE WESTERN RESERVE UNIVERSITY, OH | $402,500 | MRAD |
| 2025 | Gram-positive secretion chaperone-client interactions1R35GM159731-01 | CAHOON, LATY ADRIELLA | UNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA | $401,939 | MRAB |
| 2025 | Integrating Machine Learning and Atomistic Simulations for Accurate Prediction of Drug Molecular Crystal Solubility1R35GM159986-01 | CHENG, BINGQING | UNIVERSITY OF CALIFORNIA BERKELEY, CA | $401,250 | MRAB |
| 2025 | Engineering Modular Protein Inhibitors for Selective Targeting of Pathological Biomolecules1R35GM160474-01 | RAEESZADEH SARMAZDEH, MARYAM | UNIVERSITY OF NEVADA RENO, NV | $400,178 | MRAE |
| 2025 | Design of tunable biopolymers to understand the dynamic wound microenvironment1R35GM157100-01 | SHIN, CRYSTAL S | BAYLOR COLLEGE OF MEDICINE, TX | $400,000 | ZRG1 |
| 2025 | Unveil the Cereblon Target Atlas and Accelerate Molecular Glue Degrader Discovery1R35GM160137-01 | TENG, MINGXING | BAYLOR COLLEGE OF MEDICINE, TX | $400,000 | MRAB |
| 2025 | Dynamics of cell-matrix mechanical communication during morphogenesis1R35GM159921-01 | HERRERA PEREZ, RUTH MARISOL | UNIVERSITY OF ROCHESTER, NY | $399,198 | MRAC |
| 2025 | Molecular mechanisms of lipid transfer by bridge-like lipid transfer proteins1R35GM160234-01 | CLARK, SARAH A | OREGON STATE UNIVERSITY, OR | $399,081 | MRAB |
| 2025 | Enabling Molecular Approaches for Copper-Based Radiopharmaceuticals1R35GM157209-01 | ROBINSON, JEROME RONALD | BROWN UNIVERSITY, RI | $398,750 | MRAB |
| 2025 | Modulation of ion channels by lipids and protein folding helper enzymes1R35GM159863-01 | SCHMIDPETER, PHILIPP A.M. | UNIVERSITY OF TEXAS SAN ANTONIO, TX | $398,444 | MRAB |
| 2025 | Evolution and adaptation of Staphylococcus aureus to nutrient stress1R35GM159885-01 | CULYBA, MATTHEW J | UNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA | $397,500 | MRAA |
| 2025 | Establishing culture conditions for uncultured microbes1R35GM157104-01 | CIRA, NATE | CORNELL UNIVERSITY, NY | $397,022 | MRAA |
| 2025 | Archaea as a microbial model for developmental mechanoplasticity1R35GM156992-01 | BISSON FILHO, ALEXANDRE W | BRANDEIS UNIVERSITY, MA | $396,510 | ZRG1 |
| 2025 | Probing and controlling chirality across scales using nanophotonic platforms1R35GM157121-01 | ZHAO, YANG | UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN, IL | $396,500 | ZRG1 |
| 2025 | Synthesis and Modification of Natural Products through Inert Bond Cleavage Reactions1R35GM156918-01 | SCHUPPE, ALEXANDER W. | VANDERBILT UNIVERSITY, TN | $395,881 | MRAB |
| 2025 | Population Genomics Across Global Populations: Flexible Methods for Inference and Detecting Rare Recessive Variation1R35GM159982-01 | MOONEY, JAZLYN AMBRY | UNIVERSITY OF SOUTHERN CALIFORNIA, CA | $395,200 | MRAA |
| 2025 | Decoding epigenetic adapters of cell state1R35GM160204-01 | WILLE, CORAL K. | UNIVERSITY OF ALABAMA AT BIRMINGHAM, AL | $394,434 | MRAF |
| 2025 | Quantum sensor-enabled nanoscale magnetic resonance1R35GM160564-01 | STEVENSON, PAUL | NORTHEASTERN UNIVERSITY, MA | $394,000 | ZRG1 |
| 2025 | Lysosomal membrane dynamics during stress1R35GM157207-01 | BONET-PONCE, LUIS | OHIO STATE UNIVERSITY, OH | $393,750 | MRAC |
| 2025 | Exploring the fundamental cellular mechanisms driving cellular senescence in macrophages1R35GM156893-01 | COVARRUBIAS, ANTHONY JOSEPH | UNIVERSITY OF CALIFORNIA LOS ANGELES, CA | $393,750 | MRAD |
| 2025 | Biogeography of Microbial and Plant-Derived Redox-Active Small Molecules and Combinatorial Effects on Microbial Growth1R35GM157324-01 | MCROSE, DARCY | MASSACHUSETTS INSTITUTE OF TECHNOLOGY, MA | $393,718 | ZRG1 |
| 2025 | Dynamics of Fungal Stress Responses in the Host Environment1R35GM160442-01 | VU, BAO GIA | UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR, OK | $393,250 | ZRG1 |
| 2025 | Uncovering spatio-temporal, mechano-transcriptomic signatures of development1R35GM157082-01 | DUMITRASCU, BIANCA | COLUMBIA UNIV NEW YORK MORNINGSIDE, NY | $393,093 | ZRG1 |
| 2025 | Molecular mechanisms of ribosome biogenesis by force-producing enzymes1R35GM157075-01 | MICKOLAJCZYK, KEITH JOSEPH | RUTGERS BIOMEDICAL AND HEALTH SCIENCES, NJ | $392,500 | MRAE |
| 2025 | Mammal-virus evolution from global to local scales1R35GM156919-01 | UPHAM, NATHAN STEADMAN | ARIZONA STATE UNIVERSITY-TEMPE CAMPUS, AZ | $392,500 | ZRG1 |
| 2025 | Using Ae. aegypti as a model to understand the genomic basis of rapid and repeated evolution1R35GM159987-01 | ROSE, NOAH H | UNIVERSITY OF CALIFORNIA, SAN DIEGO, CA | $392,500 | MRAF |
| 2025 | Molecular Mechanisms of Cellular Signaling by the Proton Pumping Vacuolar ATPase1R35GM157043-01 | SHARMA, STUTI | STATE UNIVERSITY NEW YORK STONY BROOK, NY | $392,024 | MRAB |
| 2025 | Probe and Target Lysyl oxidases (LOXs) in Cancer1R35GM160304-01 | ZHOU, JIE | UNIVERSITY OF CHICAGO, IL | $391,951 | MRAE |
| 2025 | Unraveling the Biomolecular Corona on Locally Delivered Nanomedicines1R35GM160377-01 | ZIERDEN-SHININGER, HANNAH CHRISTINE | UNIV OF MARYLAND, COLLEGE PARK, MD | $391,162 | ZRG1 |
| 2025 | Evaluation of Non-covalent Antibody Drug Complexes (ADCx) for Targeted Drug Delivery1R35GM156770-01 | BORDEAU, BRANDON | UNIVERSITY OF MICHIGAN AT ANN ARBOR, MI | $390,000 | ZRG1 |
| 2025 | Molecular mechanisms of DNA replication in mitosis1R35GM156773-01 | MCCLURE, ALLISON | UNIVERSITY OF COLORADO DENVER, CO | $390,000 | MRAA |
| 2025 | Ontogeny and kinetics of innate immune cells in health and disease1R35GM156844-01 | LAM, PUI YING | MEDICAL COLLEGE OF WISCONSIN, WI | $390,000 | MRAC |
| 2025 | A covalent strategy to profile the reader proteins of glycosylation1R35GM157040-01 | YU, BINGCHEN | GEORGIA STATE UNIVERSITY, GA | $390,000 | MRAE |
| 2025 | Elucidating the mechanisms underlying DNA double-strand break repair1R35GM156956-01 | SONIAT, MICHAEL | THOMAS JEFFERSON UNIVERSITY, PA | $390,000 | ZRG1 |
| 2025 | Developing methods for high-throughput deep characterization of extracellular RNA, DNA, and vesicles in body fluids1R35GM159905-01 | NGO, THUY THI MINH | OREGON HEALTH & SCIENCE UNIVERSITY, OR | $390,000 | MRAA |
| 2025 | Understanding the molecular function and substrate specificity of palmitoyltransferases in regulating behavior1R35GM159847-01 | NELSON, JESSICA C | UNIVERSITY OF COLORADO DENVER, CO | $390,000 | MRAC |
| 2025 | Tissue-Specific Regulation of Autophagy by PROPPINs1R35GM159826-01 | STAVOE, ANDREA | UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON, TX | $390,000 | MRAD |
| 2025 | Structural Dynamics of GPCR Oligomerization: Impact on Localization and Signaling1R35GM159978-01 | ZHU, LAN | MEDICAL COLLEGE OF WISCONSIN, WI | $390,000 | MRAB |
| 2025 | Biophysical mechanisms underlying Drosophila renal tubule morphogenesis1R35GM156857-01 | VASQUEZ, CLAUDIA GABRIELA | UNIVERSITY OF WASHINGTON, WA | $388,750 | ZRG1 |
| 2025 | Exploring post-transcriptional regulators in Acinetobacter baumannii1R35GM156848-01 | GEBHARDT, MICHAEL JOHN | UNIVERSITY OF IOWA, IA | $388,750 | MRAF |
| 2025 | Investigating the mechanisms driving host-associated microbial community dynamics1R35GM157055-01 | MALLOTT, ELIZABETH K | WASHINGTON UNIVERSITY, MO | $388,750 | MRAA |
| 2025 | Probing inflammation dynamics via multi-modal tracking and control of engineered macrophages1R35GM160097-01 | SUN, TAO | NORTHEASTERN UNIVERSITY, MA | $388,000 | ZRG1 |
| 2025 | A Molecular Recognition Guidebook for Targeting Protein Loops with Covalent Ligands1R35GM160331-01 | MORGAN, BRITTANY S. | UNIVERSITY OF NOTRE DAME, IN | $387,857 | MRAE |
| 2025 | Gene regulatory networks for hair cell regeneration1R35GM156916-01 | JIMENEZ, ERIN ALISA | JOHNS HOPKINS UNIVERSITY, MD | $387,500 | MRAC |
| 2025 | Calcium sensing and mitochondrial homeostasis1R35GM160213-01 | TOMAR, DHANENDRA | WAKE FOREST UNIVERSITY HEALTH SCIENCES, NC | $387,500 | MRAD |
| 2025 | New Catalytic Technologies Impactful to Synthesis of Pharmaceuticals1R35GM159617-01 | HANDA, SACHIN | UNIVERSITY OF MISSOURI-COLUMBIA, MO | $386,617 | MRAE |
| 2025 | Improving accessibility and efficacy of in vivo forward genetic screening1R35GM156990-01 | VANDUSEN, NATHAN JAMES | INDIANA UNIVERSITY INDIANAPOLIS, IN | $386,013 | MRAF |
| 2025 | Understanding Cell Behavior in Precise Multifunctional Biomimetic Matrices Prepared via 3D Printing1R35GM156809-01 | PAGE, ZACHARIAH ALLEN | UNIVERSITY OF TEXAS AT AUSTIN, TX | $385,671 | ZRG1 |
| 2025 | CHEMICAL STRATEGIES FOR CONFORMATIONAL CONTROL OF BIOACTIVE PEPTIDES1R35GM160477-01 | NEWBERRY, ROBERT WILLIAM | UNIVERSITY OF TEXAS AT AUSTIN, TX | $385,671 | MRAE |
| 2025 | Molecular Architecture and Function of synaptic AMPA receptor complexes1R35GM160303-01 | KLYKOV, OLEG V. | UNIVERSITY OF TEXAS HLTH SCIENCE CENTER, TX | $385,639 | MRAB |
| 2025 | Complex Amines from Simple Amino Acids via Pyridoxal-Mimicking Radical (Photo)Catalysis1R35GM157011-01 | LIPSHULTZ, JEFFREY MICHAEL | STATE UNIVERSITY NEW YORK STONY BROOK, NY | $385,298 | MRAE |
| 2025 | De novo evolved lipid transport and processing mechanisms interfacing human cells1R35GM160156-01 | GARTEN, MATTHIAS | STANFORD UNIVERSITY, CA | $385,000 | MRAB |
| 2025 | Statistical approaches for integrating multi-view, multi-section and multi-sample spatial transcriptomics data to decipher disease mechanisms1R35GM159880-01 | HU, JIAN | EMORY UNIVERSITY, GA | $384,722 | MRAF |
| 2025 | Deciphering the Interactome and Functions of Disordered Microproteins1R35GM157126-01 | MARTINEZ, THOMAS FARID | UNIVERSITY OF CALIFORNIA-IRVINE, CA | $384,527 | MRAE |
| 2025 | The control of sporulation and antibiotic production through c-di-GMP signaling1R35GM156858-01 | GALLAGHER, KELLEY ANN | CORNELL UNIVERSITY, NY | $383,746 | ZRG1 |
| 2025 | Computational Studies of Molecular Medicine for Voltage-Gated Sodium Channels1R35GM160133-01 | LI, JING | UNIVERSITY OF MISSISSIPPI, MS | $383,008 | MRAE |
Showing the 200 most recent of 470 awards.
Data: Grants.gov's daily extract and NIH's notice pages and award files, in ScienceGraph release conductgrants-2026-11-09-0.1.0. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.