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NIH funding notice PAR-23-255

Secondary Analysis and Integration of Existing Data to Elucidate Cancer Risk and Related Outcomes (R21 Clinical Trials Not Allowed)

Closed on May 23, 2025.

Posted
August 1, 2023
Close date
May 23, 2025
Activity codes
R21
Institutes taking part
NCI, NHGRI, NIA, NIDCR

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

  1. Reissues: PAR-20-277 Secondary Analysis and Integration of Existing Data to Elucidate the Genetic Architecture of Cancer Risk and Related Outcomes (R21 Clinical Trials Not Allowed)
  2. 2 steps back: PA-17-243 Secondary Analysis and Integration of Existing Data to Elucidate the Genetic Architecture of Cancer Risk and Related Outcomes (R21)

Replaced by PAR-25-096.

Who won it before

21 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $5,914,338 in first-year total cost, median $239,307.

Most frequent study sections

  1. Cancer Genetics Study Section[CG]6
  2. Social and Environmental Determinants of Health Study Section[SEDH]3
  3. Cancer and Hematologic Disorders Study Section[CHD]2
  4. Genomics, Computational Biology and Technology Study Section[GCAT]2
  5. Basic Cancer Immunobiology Study Section[BCIB]1

Most frequent institutions

  1. UNIVERSITY OF MINNESOTA4
  2. BAYLOR COLLEGE OF MEDICINE1
  3. BRIGHAM AND WOMEN'S HOSPITAL1
  4. CINCINNATI CHILDRENS HOSP MED CTR1
  5. DANA-FARBER CANCER INST1
Competing awards under PAR-23-255 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2025Early-life exposures to extreme weather-related factors and pediatric thyroid cancer risk1R21CA297737-01A1DEZIEL, NICOLEMA, XIAOMEIYALE UNIVERSITY, CT$431,386SEDH
2025The influence of extreme weather events on emergency department utilization among cancer patients in Florida1R21CA304866-01BULKA, CATHERINEKRESOVICH, JACOB KH. LEE MOFFITT CANCER CTR & RES INST, FL$423,462CHD
2025Influence of Menthol Cigarette Smoking on Lung Cancer Screening Eligibility in a National Prospective Study1R21CA301405-01BOVER MANDERSKI, MICHELLE T.RUTGERS BIOMEDICAL AND HEALTH SCIENCES, NJ$403,689LHB
2025Socio-environmental Factors, Accelerated Aging, and Cancer Risks and Outcomes in Middle-Aged and Older Adults1R21CA297739-01A1EVERSON-ROSE, SUSAN A.PRIZMENT, ANNAUNIVERSITY OF MINNESOTA, MN$386,612SEDH
2025Cancer Risks from Unregulated Contaminants of Public Water Systems1R21CA305033-01DE ROOS, ANNECLAIRE JDREXEL UNIVERSITY, PA$376,314SEDH
2025Pancancer discovery and exploration of shared splicing neoantigens1R21CA300922-01SALOMONIS, NATHAN G.CINCINNATI CHILDRENS HOSP MED CTR, OH$225,101BCIB
2025Pathways to Prevention: Exploring Social Determinants of Health in Early Onset Colorectal Cancer1R21CA301113-01MOORE, JUSTIN XAVIERTSAI, MENG-HANUNIVERSITY OF KENTUCKY, KY$192,610ODHS
2025Obesity related Methylation markers for obesity-related cancers1R21CA293759-01A1ZHAO, NAISITUFTS UNIVERSITY BOSTON, MA$5,407CHD
2024Alternative splicing and isoform expression as mediators for the genetic etiology of breast cancer1R21CA293419-01BHATTACHARYA, ARJUNLINDSTROEM, SARAUNIVERSITY OF TX MD ANDERSON CAN CTR, TX$407,321CG
2023Leveraging the Hidden Genome to Recover the Missing Heritability of Cancer1R21CA270428-01A1 · under PAR-20-277BEGG, COLIN BSHEN, RONGLAISLOAN-KETTERING INST CAN RESEARCH, NY$455,111CG
2023scSNVariome - single cell SNVs driving cancer dynamics1R21CA271066-01A1 · under PAR-20-277HORVATH, ANELIAGEORGE WASHINGTON UNIVERSITY, DC$239,307CG
2023The genetic and epigenetic cartography of multiple myeloma1R21CA280584-01 · under PAR-20-277BARWICK, BENJAMIN GABRIELEMORY UNIVERSITY, GA$209,982CG
2021Characterization of extrachromosomal DNAs in tumors through computational analysis of single-cell and bulk sequencing data1R21CA256575-01A1 · under PAR-20-277VERHAAK, ROEL GWJACKSON LABORATORY, ME$406,138GCAT
2021Multidisciplinary Study of Folate Intake and Colorectal Cancer1R21CA252962-01A1 · under PAR-20-277ZHANG, XUEHONGBRIGHAM AND WOMEN'S HOSPITAL, MA$276,208CPSS
2021Role of genetic and epigenetic alterations in CFTR in colorectal cancer1R21CA256749-01A1 · under PAR-20-277PRIZMENT, ANNASCOTT, PATRICIA MUNIVERSITY OF MINNESOTA, MN$229,291CHSA
2020Curated prostate cancer data for novel and reproducible prognostic modeling1R21CA241647-01A1 · under PA-17-243COSTELLO, JAMES CHRISTOPHERTYEKUCHEVA, SVITLANADANA-FARBER CANCER INST, MA$265,599CHSB
2020Copy Number Variation and Lung Cancer: Disease Risk and Mechanisms1R21HG010925-01A1 · under PA-17-243XIAO, FEIFEIUNIVERSITY OF SOUTH CAROLINA AT COLUMBIA, SC$186,525CG
2019Germline genetic factors regulating immune response to tumors and their contribution to colorectal cancer risk and prognosis1R21CA230486-01A1 · under PA-17-243HUYGHE, JEROEN RFRED HUTCHINSON CANCER RESEARCH CENTER, WA$229,680GHD
2019Genetic interaction analysis involving oncogenesis-related genes in lung cancer1R21CA235464-01A1 · under PA-17-243LI, YAFANGBAYLOR COLLEGE OF MEDICINE, TX$210,597CG
2019Integrative methods for finding genetic interactions associated with cancer risk1R21CA235352-01 · under PA-17-243MYERS, CHAD LUNIVERSITY OF MINNESOTA, MN$187,241GCAT
2018Bidimensional integration for pan-omics pan-cancer analysis1R21CA231214-01 · under PA-17-243LOCK, ERIC FUNIVERSITY OF MINNESOTA, MN$166,757BMRD

Data: Grants.gov's daily extract and NIH's notice pages and award files, in ScienceGraph release conductgrants-2026-11-09-0.1.0. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.

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