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NIH funding notice PAR-23-286

NCI Pathway to Independence Award for Early-Stage Postdoctoral Researchers (K99/R00 - Independent Clinical Trial Not Allowed)

Closed on October 14, 2026.

Posted
November 8, 2023
Close date
October 14, 2026
Activity codes
Not stated on the notice page
Institutes taking part
Not stated on the notice page

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

Its page was not saved, so the notices it replaced are not known.

Who won it before

21 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $2,889,995 in first-year total cost, median $133,955.

Most frequent study sections

  1. Special Emphasis Panel[ZCA1 RTRB-U (O1)]10
  2. Special Emphasis Panel[ZCA1 RTRB-U (M1)]6
  3. Special Emphasis Panel[ZCA1 RTRB-U (J1)]5

Most frequent institutions

  1. STANFORD UNIVERSITY3
  2. DANA-FARBER CANCER INST2
  3. SLOAN-KETTERING INST CAN RESEARCH2
  4. BRIGHAM AND WOMEN'S HOSPITAL1
  5. HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH1
Competing awards under PAR-23-286 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2025Engineering novel CAR-T cell therapy to overcome the cancer cell glycocalyx1K99CA303346-01PARK, SANGWOOMASSACHUSETTS GENERAL HOSPITAL, MA$176,040ZCA1
2025Mapping Intercellular Protein Trafficking in Glioblastoma with Esterase-Activated Proximity Labeling1K99CA297018-01DAI, SHIZHONGSTANFORD UNIVERSITY, CA$170,655ZCA1
2025Dissecting the impact of tumor-immune spatial interactions in mismatch-repair stratified colorectal cancers1K99CA300495-01WALA, JEREMIAHDANA-FARBER CANCER INST, MA$170,641ZCA1
2025Inflammation and Hepatocellular Carcinoma: A Multiomics Approach to Improve Early Detection, Causal Inference, and Lifestyle Based Prevention1K99CA296755-01ZHANG, XINYUANBRIGHAM AND WOMEN'S HOSPITAL, MA$165,883ZCA1
2025Chromosomal instability and radiation sensitivity in meningioma1K99CA296996-01CHEN, WILLIAM CUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$162,756ZCA1
2025Targeting the evolving immunopeptidome of metastatic colorectal cancer1K99CA297011-01LEE, JAEYOPSLOAN-KETTERING INST CAN RESEARCH, NY$154,642ZCA1
2025Beyond Lysis: Deciphering the Role of Perforin-Mediated Ferroptosis in Anti-Tumor Immunity1K99CA299410-01BELL, HANNAH NOELLEUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$139,968ZCA1
2025Engineered Living Materials as Programmable Therapeutic Implants for Pancreatic Cancer1K99CA300498-01HARIMOTO, TETSUHIRODANA-FARBER CANCER INST, MA$137,995ZCA1
2025Reinvigorating the overdominant model of tumor suppression1K99CA299411-01XU, HAIQINGSTANFORD UNIVERSITY, CA$135,774ZCA1
2025Rewiring fusion oncogenes to activate apoptosis1K99CA296700-01GOURISANKAR, SAISTANFORD UNIVERSITY, CA$135,594ZCA1
2025Determining how cancer cachexia influences gluconeogenesis1K99CA300496-01ZHANG, YICHIMASSACHUSETTS INSTITUTE OF TECHNOLOGY, MA$133,955ZCA1
2025Developing and Validating Prognostic Models for Black women with Endometrial Cancer following Hysterectomy1K99CA297013-01PEERI, NOAH CHARLESSLOAN-KETTERING INST CAN RESEARCH, NY$132,825ZCA1
2025The role of loss of Y chromosome across the prostate cancer continuum1K99CA303777-01WANG, ANQIUNIVERSITY OF SOUTHERN CALIFORNIA, CA$129,058ZCA1
2025Human leukocyte antigen and immune response in non-small cell lung cancer: A multi-omics approach1K99CA297010-01WANG, XINANHARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH, MA$127,629ZCA1
2025Enhancing TIL efficacy in NSCLC through epigenetic reprogramming and computational modeling1K99CA303792-01PLAUGHER, DANIEL RAYUNIVERSITY OF KENTUCKY, KY$124,546ZCA1
2025Dissecting the contribution of mis-splicing in cancer phenotypes through multi-omic single-cell approaches1K99CA297005-01CORTES LOPEZ, MARIELAWEILL MEDICAL COLL OF CORNELL UNIV, NY$122,032ZCA1
2025Systematically Investigate Anti-Cancer Drug’s Modulation on T Cells in Tumor Microenvironment1K99CA297120-01A1WANG, YUEUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$121,857ZCA1
2025Paving the way for bystander T cell immunotherapies1K99CA296729-01MAURICE, NICHOLAS JOSEPHUNIVERSITY OF MINNESOTA, MN$113,937ZCA1
2025SERPINE family genes in rhabdoid tumorigenesis1K99CA297000-01LI, YIZEWASHINGTON UNIVERSITY, MO$113,372ZCA1
2025Sumiki’s Acid, a de novo Dietary Compound Generated from Food Processing, Reprograms NK Cells for Cancer Immunoprevention1K99CA303782-01XIE, ZHICHENGUNIVERSITY OF CHICAGO, IL$113,203ZCA1
2025Clarifying the relationship between air pollution and lung and breast cancer with a spatial data science approach1K99CA296217-01A1BOYLE, JOSEPH RUSSELLVIRGINIA COMMONWEALTH UNIVERSITY, VA$107,633ZCA1

Data: Grants.gov's daily extract and NIH's notice pages and award files, in ScienceGraph release conductgrants-2026-11-09-0.1.0. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.

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