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NIH funding notice PAR-24-075

Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Clinical Trial Not Allowed)

Closed on May 23, 2025.

Posted
December 22, 2023
Close date
May 23, 2025
Activity codes
R01
Institutes taking part
OD, NCCIH, NEI, NHLBI, NHGRI, NIA, NIAAA, NIAID, NIAMS, NIBIB, NICHD, NIDCD, NIDCR, NIDDK, NIDA, NIMHD, NINR, NLM, NCI, NIEHS, NIMH, ORIP

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

  1. Reissues: PAR-21-038 Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Clinical Trial Not Allowed)

Replaced by PAR-25-322.

Who won it before

195 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $109,307,207 in first-year total cost, median $502,949.

Most frequent study sections

  1. Neurotoxicology and Alcohol Study Section[NAL]8
  2. Integrative Myocardial Physiology/Pathophysiology B Study Section[MPPB]5
  3. Pathobiology of Kidney Disease Study Section[PBKD]5
  4. Biomaterials and Biointerfaces Study Section[BMBI]4
  5. Pregnancy and Neonatology Study Section[PN]4

Most frequent institutions

  1. UNIVERSITY OF CALIFORNIA, SAN DIEGO7
  2. UNIVERSITY OF PITTSBURGH AT PITTSBURGH7
  3. UNIVERSITY OF WASHINGTON6
  4. UNIVERSITY OF CALIFORNIA, SAN FRANCISCO5
  5. OREGON HEALTH & SCIENCE UNIVERSITY4
Competing awards under PAR-24-075 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2025Capturing social and cognitive health dynamics as digital risk biomarkers of Alzheimer's disease1RF1AG088206-01A1BECK, EMORIE DANIELLEUNIVERSITY OF CALIFORNIA AT DAVIS, CA$3,424,229SPIP
2025Magnetic Resonance Imaging of Outbred Rats with Variable Vulnerability to Compulsive Alcohol Use1R01AA031958-01A1CARRETTE, LIESELOT LEEN GEORGESUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$2,250,249NAL
2025Neuropeptidergic regulation of valence processing underlying the sex differences in AUD1R01AA031656-01A1LI, HAONORTHWESTERN UNIVERSITY, IL$2,145,105NAL
2025Examination of the dynamic relationships of sleep, physical activity, and circadian rhythmicity with neurobehavioral heterogeneity in ADHD1R01MH136970-01A1ROSCH, KERI SHIELSHUGO W. MOSER RES INST KENNEDY KRIEGER, MD$826,902CPDD
2025Mechanisms of Macroglossia in Beckwith-Wiedemann Syndrome1R01DE033646-01A1KALISH, JENNIFER MELISSACHILDREN'S HOSP OF PHILADELPHIA, PA$818,112ZRG1
2025Targeting Regulatory T cells for Factor VIII Tolerance1R01HL180328-01BATSULI, GLAIVYSTANFORD UNIVERSITY, CA$787,021HTBT
2025Multimodal imaging of prenatal alcohol exposure: Mechanisms underlying spatial navigation memory deficits in children and adolescents1R01AA031657-01A1CANDELARIA-COOK, FELICHALOVELACE BIOMEDICAL RESEARCH INSTITUTE, NM$733,704NAL
2025Major histocompatibility complex gene editing to prevent hematopoietic stem cell graft rejection1R01HL180336-01LI, HOJUNUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$725,971ITA
2025Role of cardiac clock misalignment in promoting arrhythmias in swine and donor human hearts1R01HL174461-01A1ARAS, KEDAR KIRTIKUMARSTATE UNIVERSITY OF NEW YORK AT BUFFALO, NY$721,041TDPS
2025Mechanisms of operant reward seeking in prefrontal somatostatin-expressing interneurons1R01DA059368-01A1CUMMINGS, KIRSTIE ALYSSAUNIVERSITY OF ALABAMA AT BIRMINGHAM, AL$711,071LMDN
2025Dissecting the circuit-level mechanisms of ultrasound neuromodulation1R01EB036474-01A1DI IANNI, TOMMASOUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$701,011ZRG1
2025Quantitative Dynamic Monitoring of MSCs and MSC-EVs in a Mouse Model of Intracerebral Hemorrhage1R01EB036468-01KUDDANNAYA, SHREYASUNIVERSITY OF MIAMI SCHOOL OF MEDICINE, FL$663,854IGIS
2025Development and Validation of the Sibling Prosocial Relationship Questionnaire1R01HD115632-01A1HOLMES, MEGAN RENEECASE WESTERN RESERVE UNIVERSITY, OH$662,974PDRP
2025Examining mobility restrictions through the lens of post-stroke apathy1R01HD115526-01A1LEECH, KRISTAN A.UNIVERSITY OF SOUTHERN CALIFORNIA, CA$647,043MFSR
2025Bacteriophages in dental caries: Roles and potential as a therapy1R56DE034689-01KASPAR, JUSTIN RAYLEE, KYULIMOHIO STATE UNIVERSITY, OH$645,988ODCS
2025Defining the impact of developmental herbicide exposures on gut microbiome physiology and interactions with health1R01ES036174-01A1GAULKE, CHRISTOPHER AUNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN, IL$622,235EDD
2025An Intelligent Biorobot for the Regenerative Rehabilitation of Volumetric Muscle Loss Defects1R01AR083865-01A1SIKDER, PRABAHACLEVELAND STATE UNIVERSITY, OH$616,256MRS
2025Establishing a novel 13C-labeled metabolite library for the study of dental caries1R56DE034690-01MOMENI, STEPHANIEOREGON HEALTH & SCIENCE UNIVERSITY, OR$597,807ODCS
2025mitochondrial DNA leakage promotes inflammation and intervertebral disc degeneration1R01AR086165-01ANSARI, MOHAMMAD YUNUSNORTHEAST OHIO MEDICAL UNIVERSITY, OH$584,330SBSR
2025Cellular heterogeneity in mitochondrial calcium dynamics in heart failure1R01HL178419-01JADIYA, POOJAWAKE FOREST UNIVERSITY HEALTH SCIENCES, NC$507,096BBHV
2025Towards MRI-based detection and categorization of invasive high grade glioma subtypes1R37CA288396-01A1BEEMAN, SCOTT CHARLESARIZONA STATE UNIVERSITY-TEMPE CAMPUS, AZ$498,705EITA
2025A mechanistic investigation of SerpinB3 and its role in psoriasis1R01AR085579-01YARON, JORDAN ROBINARIZONA STATE UNIVERSITY-TEMPE CAMPUS, AZ$390,913SCTS
2024A Mixed Methods Analysis of Pediatric Voice Therapy1R01DC021407-01A1 · under PAR-21-038HELLER MURRAY, ELIZABETH SALMONTEMPLE UNIV OF THE COMMONWEALTH, PA$835,439ZRG1
2024SARS-CoV-2 and Social Determinants of Health Impact on Inflammation Associated Depression Risk (SSIDR)1R01MH136492-01 · under PAR-21-038KIM, LINDA Y.CEDARS-SINAI MEDICAL CENTER, CA$833,123NMBH
2024Social Media Use and Mental Health among Racially/Ethnically Minoritized Adolescents1R01MH136979-01 · under PAR-21-038WANG, JUNTEXAS A&M AGRILIFE RESEARCH, TX$757,971PDRP
2024Defining Relationships of Early Mediators and Moderators of Sleep (DREAMS)1R01HL170100-01A1 · under PAR-21-038BATES, RANDIUNIVERSITY OF CINCINNATI, OH$752,991MESH
2024Investigating CXCR3 Blockade as Precision Therapy for Cardiac Sarcoidosis using Single-Cell Multi-omics and TCR Phenotyping1R01HL174432-01 · under PAR-21-038ZHU, HANSTANFORD UNIVERSITY, CA$751,954TDPS
2024PET Biomarker for synaptic density changes after radiation therapy1R01CA275767-01A1 · under PAR-21-038ABOIAN, MARIAMCHILDREN'S HOSP OF PHILADELPHIA, PA$737,118RTB
2024Elucidating the Signaling Landscapes Underlying Cellular and Regional Specification During Human Brain Development1R01MH133612-01A1 · under PAR-21-038BIREY, FIKRIEMORY UNIVERSITY, GA$731,648MNG
2024Integrating Acute and Ambulatory Care with Post-Discharge Monitoring and Machine Learning1R01HL172794-01 · under PAR-21-038KIM, DAVID ANDREWRAJPURKAR, PRANAVSTANFORD UNIVERSITY, CA$726,452CIDH
2024Disease transmission along complex human-animal networks: a novel method for improving zoonotic disease modeling1R01AI184331-01 · under PAR-21-038MEISNER, JULIANNEUNIVERSITY OF WASHINGTON, WA$720,456TVZ
2024Developing and Validating a Multi-Dimensional Scale of Sexual Health1R01HD114578-01 · under PAR-21-038LUDWIG, VERA URSULAUNIVERSITY OF PENNSYLVANIA, PA$715,829SPIP
2024Identifying and modulating pathologic T cells that govern oral mucosal immune related adverse events from immune checkpoint blockade1R01DE033038-01A1 · under PAR-21-038KULKARNI, RAJAN P.OREGON HEALTH & SCIENCE UNIVERSITY, OR$705,441CIC
2024Technology-based Sleep Self-Management Intervention for Adults with Subarachnoid Hemorrhage1R56HL167681-01A1 · under PAR-21-038BYUN, EEESEUNGUNIVERSITY OF WASHINGTON, WA$704,186BMHO
2024Thrombospondin-1's role in heart failure with preserved ejection fraction (HFpEF)1R56HL169285-01A1 · under PAR-21-038STEPPAN, JOCHENJOHNS HOPKINS UNIVERSITY, MD$654,207MPPB
2024Intersection of Severe Respiratory Infection and Viral Latency1R01AI181923-01 · under PAR-21-038STEED, ASHLEYWASHINGTON UNIVERSITY, MO$635,732IMII
2024Modeling Adolescent Health Care Decision-Making for Vaccines: A Community- Based Participatory Approach1R01HD110428-01A1 · under PAR-21-038CHU, KAR-HAIUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$633,148CIHB
2024Genetic dissection of defensin signaling in urinary tract infections1R01DK140039-01 · under PAR-21-038DONG, XINTONGUNIVERSITY OF TEXAS DALLAS, TX$632,600KUFD
2024Enhancing Visual Accessibility of Indoor Spaces1R01EY036360-01 · under PAR-21-038XIONG, YINGZIJOHNS HOPKINS UNIVERSITY, MD$624,379ZRG1
2024Leveraging pediatric state-specific functional brain network dynamics to predict developmental outcomes1R01HD115540-01A1 · under PAR-21-038WHEELOCK, MURIAH DWASHINGTON UNIVERSITY, MO$621,292EITN
2024Role of MUC1 in the host defense against urinary tract infection1R01DK135862-01A1 · under PAR-21-038AL-BATAINEH, MOHAMMADUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$585,993ZRG1
2024Integrated Detection and Classification of Sepsis via Tensor Methods Using EHR1R01HL169347-01A1 · under PAR-21-038ZHANG, ANRUDUKE UNIVERSITY, NC$583,160CDMA
2024Central nervous system mechanisms and treatment response in chronic ocular surface pain1R01EY036357-01 · under PAR-21-038DE LOTT, LINDSEY BLAKEUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$578,123NPI
2024Role of CHAMP1, a neurodevelopmental disorder high risk gene, in human brain development and function1R01HD113594-01A1 · under PAR-21-038BERTO, STEFANOMEDICAL UNIVERSITY OF SOUTH CAROLINA, SC$556,895DBD
2024Targeting PFC interneurons for personalized treatments in OUD1R01DA058704-01A1 · under PAR-21-038JOFFE, MAX EUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$538,018NMB
2024When actin's not actin like actin: Nuclear actin impacts transcription and aging1R01AG079806-01A1 · under PAR-21-038HIGUCHI-SANABRIA, RYOUNIVERSITY OF SOUTHERN CALIFORNIA, CA$536,575CMAD
2024PFAS increases susceptibility to infection-mediated PTB1R01ES035692-01A1 · under PAR-21-038PETRIELLO, MICHAEL CURTISWAYNE STATE UNIVERSITY, MI$533,723PN
2024Never Again: Advancing the Prevention of Recurrent Child Sexual Abuse1R01HD114586-01A1KOBULSKY, JULIATEMPLE UNIV OF THE COMMONWEALTH, PA$524,780CIHB
2024Cerebrovascular O-GlcNAcylation Worsens Diabetes-associated Neurovascular Injury and Recovery Post-stroke1R56HL169223-01A1 · under PAR-21-038MCCARTHY, CAMERONUNIVERSITY OF SOUTH CAROLINA AT COLUMBIA, SC$511,702ZRG1
2024A circuit mechanism for the interactions between distinct learning systems1R01MH136968-01 · under PAR-21-038WOLFF, STEFFENUNIVERSITY OF MARYLAND BALTIMORE, MD$500,228LMDN
2024Investigation of the renin-angiotensin system at the maternal-fetal interface.1R01HD115535-01 · under PAR-21-038VROOMAN, LISA ANNEOREGON HEALTH & SCIENCE UNIVERSITY, OR$493,409PN
2024Neuroinflammatory GeroMiRs and Alcohol: Defining Mechanisms of ADRD1R01AA030741-01A1 · under PAR-21-038SMATHERS MCCULLOUGH, REBECCA LEANNEUNIVERSITY OF COLORADO DENVER, CO$492,337NAL
2024Differentiating slow from rapidly progressive ADPKD by cell-specific mitochondrial and transcriptional profiles1R01DK134310-01A1 · under PAR-21-038LASSEIGNE, BRITTANY NICOLEUNIVERSITY OF ALABAMA AT BIRMINGHAM, AL$491,400PBKD
2024Neural circuitry mediating lactation-induced hyperphagia1R01HD113522-01 · under PAR-21-038SWEENEY, PATRICKUNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN, IL$490,804POMD
2024Molecular mechanisms of sympatho-excitation in cardiovascular disease1R01HL174439-01 · under PAR-21-038AKIN, ELIZABETHUNIVERSITY OF NEVADA RENO, NV$484,266BBHV
2024Engineering bZIP family transcription factors for therapeutic T-cell persistence and effector function1R37CA285289-01A1 · under PAR-21-038FOIGHT, GLENNA WINKBAYLOR COLLEGE OF MEDICINE, TX$483,041CIC
2024Effects of Early-life Cannabinoid Exposure on Prefrontal Circuitry and Cognitive Behavior across Development1R01DA059378-01 · under PAR-21-038CHE, ALICIA YUEYALE UNIVERSITY, CT$465,460PMDA
2024Novel MUC1 Theranostic Peptides for Imaging and Treatment of Triple-Negative Breast Cancer1R37CA278744-01A1 · under PAR-21-038BEINAT, CORINNESTANFORD UNIVERSITY, CA$462,860IPCA
2024Nuclear skeletal muscle alpha-actin and intranuclear rod myopathy1R01AR084437-01 · under PAR-21-038KWARTLER, CALLIE SUNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON, TX$437,154SMEP
2024Brain Vascular Signatures in Drug-induced Recurrent Hypoglycemia and Associated Cognitive Dysfunction1R01DK138939-01 · under PAR-21-038CHEN, YUN-SHENGUNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN, IL$433,576ZRG1
20243D dynamic contrast optical coherence microscopy for organoid studies1R01EB036005-01 · under PAR-21-038HUANG, SHU-WEIUNIVERSITY OF COLORADO, CO$402,135ISD
2024Genetic editing and cell therapy for correction of CLCN7 mutations in osteopetrosis1R01AR082858-01A1 · under PAR-21-038JACOME-GALARZA, CHRISTIAN EBRIGHAM AND WOMEN'S HOSPITAL, MA$395,537SBDD
2024Evaluation of Pb-induced perturbations in the central and enteric nervous system1R01ES035013-01A1 · under PAR-21-038MORTON, PAUL DAVIDVIRGINIA POLYTECHNIC INST AND ST UNIV, VA$395,403NAL
2024Impact of nigral and extranigral neurodegeneration on aerodigestive discoordination in a pesticide model of Parkinson's disease1R01ES035118-01A1 · under PAR-21-038GOULD, FRANCOISROWAN UNIVERSITY SCHOOL/OSTEOPATHIC MED, NJ$390,823MFSR
2024Genome-wide assessment of transcriptional state history1R01HG013472-01 · under PAR-21-038BREUSS, MARTIN WERNERUNIVERSITY OF COLORADO DENVER, CO$390,000GVE
2024Stromal Effects in Head and Neck Squamous Cell Carcinoma1R01CA288366-01 · under PAR-21-038CHEN, CHI-DERUNIVERSITY OF PENNSYLVANIA, PA$371,719THI
2024Health care transition utilization and outcomes for youth with mental, behavioral, and developmental disorders1R01MH131597-01A1 · under PAR-21-038WISK, LAUREN ELISABETHUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$353,039ODHS
2024Investigating the role Ikaros variants in multiple myeloma pathophysiology and drug sensitivity1R01CA282251-01A1 · under PAR-21-038SINGH, IRTISHATEXAS A&M UNIVERSITY HEALTH SCIENCE CTR, TX$345,571GRIC
2024Extracellular Matrix Regulation of Inflammatory Signaling in Tendon1R01AR083343-01 · under PAR-21-038ABRAHAM, ADAM CHRISTOPHERUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$343,200SBSR
2024Cortical odor processing for social recognition1R01DC020927-01A1 · under PAR-21-038BOLDING, KEVIN AMONELL CHEMICAL SENSES CENTER, PA$334,250NIC
2024Mechanisms of right ventricular dysfunction in type 2 diabetes1R56HL164328-01A1 · under PAR-21-038BRUNS, DANIELLE REULANDUNIVERSITY OF WYOMING, WY$323,277MPPB
2024Improving Automated Hearing Aid Safety and Audibility; External-Ear Amplification Predictions Based on Height, Not Age1R01DC020699-01A1 · under PAR-21-038GRINN, SARAHCENTRAL MICHIGAN UNIVERSITY, MI$271,217AUD
2023Balancing epithelial cell resistance and resilience to respiratory viral infections1R01HL162642-01A1 · under PAR-21-038ORDOVAS-MONTANES, JOSE MANUELBOSTON CHILDREN'S HOSPITAL, MA$869,852LCMI
2023Molecular mechanisms of aging and accelerated aging in the human brain1R01AG079799-01A1 · under PAR-21-038MAVRIKAKI, MARIABETH ISRAEL DEACONESS MEDICAL CENTER, MA$841,971MNG
2023Mechanisms of SARS-CoV-2 pathogenesis during HIV/SIV infection1R01HL165933-01A1 · under PAR-21-038O'CONNOR, MEGAN AUNIVERSITY OF WASHINGTON, WA$815,811ZRG1
2023Developmental Origins of Cardiovascular Disease in Offspring from Non-Human Primate Pregnancies at Advanced Maternal Age1R01HL164434-01A1 · under PAR-21-038CILVIK, SARAH NWAKE FOREST UNIVERSITY HEALTH SCIENCES, NC$784,802PN
2023Cognitive sequelae of cerebrovascular and gut dysfunction in post-acute COVID-19 syndrome.1R01NS129407-01A1 · under PAR-21-038VAKHTIN, ANDREI ALOVELACE BIOMEDICAL RESEARCH INSTITUTE, NM$737,345ASG
2023Identifying mechanisms of maternal-infant obesity risk transmission: The role of appetite, sleep, and circadian rhythms1R01HL166171-01A1 · under PAR-21-038CONLON, RACHEL P. KOLKOUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$724,456LCBH
2023Sodium in the Skin and Atopic Dermatitis: The SIS-AD Study1R01AR082831-01 · under PAR-21-038ABUABARA, KATRINA ELAINEUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$705,637ACTS
2023Functional characterization of schizophrenia rare variants using genetically engineered human iPSCs1R01MH129277-01A1 · under PAR-21-038LI, PANJOHNS HOPKINS UNIVERSITY, MD$696,676ZRG1
2023Bio-Responsive and Immune Protein-Based Therapies for Inhibition of Proteolytic Enzymes in Dental Tissues1R01DE032302-01 · under PAR-21-038PIOVEZAN FUGOLIN, ANA PAULAOREGON HEALTH & SCIENCE UNIVERSITY, OR$661,250ZRG1
2023Positive Affect and Pediatric Asthma: An Innovative Positive Psychology Model to Improve Asthma Management and Health1R01HL166175-01A1 · under PAR-21-038JENKINS, BROOKECHAPMAN UNIVERSITY, CA$660,090BMHO
2023Wildfires and Infant Health1R01ES033963-01A1 · under PAR-21-038BOUDREAUX, MICHEL HUNIV OF MARYLAND, COLLEGE PARK, MD$611,926ZRG1
2023Develop Conditionally Armored CAR Macrophage Therapy for Pancreatic Cancer1R01CA275761-01A1 · under PAR-21-038HOU, PINGPINGRUTGERS BIOMEDICAL AND HEALTH SCIENCES, NJ$602,518CIC
2023VLA-4–targeted 67Cu-LLP2A preconditioning enhances efficacy of T-cell-based adoptive immunotherapy1R01CA275766-01A1 · under PAR-21-038PATEL, RAVI BHASKERUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$595,764ZRG1
2023Neurodevelopment of exploration and alcohol problems in adolescence1R01AA030283-01A1 · under PAR-21-038HOGEVEEN, JEREMY PUNIVERSITY OF NEW MEXICO, NM$593,919NPAS
2023Impact of tissue resident memory T cells on the neuro-immune pathophysiology of anterior eye disease1R01EY033712-01A1 · under PAR-21-038SKORPUT, ALEXANDERDARTMOUTH COLLEGE, NH$566,522PED2
2023Nervous system influences on recovery from painful rotator cuff tears1R01AR080058-01A1 · under PAR-21-038POZZI, FEDERICOUNIVERSITY OF FLORIDA, FL$555,892NPI
2023The role of the female and male reproductive microenvironment in fertility fitness1R01HD110367-01 · under PAR-21-038BRUBAKER, DOUGLASFARR ZUEND, CHRISTINACASE WESTERN RESERVE UNIVERSITY, OH$555,722ICER
2023Reciprocal interactions between cortical circuit dysfunction and α-synuclein pathology1R01NS129517-01 · under PAR-21-038ZEIGER, WILLIAM ABELUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$543,162CDIN
2023The functional role of frontal and parietal feedback to visual cortex in selective visual attention1R01EY033726-01A1 · under PAR-21-038FIEBELKORN, IAN C.UNIVERSITY OF ROCHESTER, NY$542,601NBVP
20233D Bioprinted Human Model of Duchenne Muscular Dystrophy (DMD) Cardiomyopathy to Study Disease Progression with Imposed Force and Precise Gene Editing1R01HL167689-01 · under PAR-21-038KAMDAR, FORUM DUNIVERSITY OF MINNESOTA, MN$539,283MPPA
2023The genome integrity and epigenome of sperm from men with recurrent pregnancy loss1R01HD108124-01A1 · under PAR-21-038MAK, WINIFRED WUNIVERSITY OF TEXAS HLTH SCIENCE CENTER, TX$512,633ZRG1
2023Targeted Mitochondrial Delivery Systems for Vascular Interventions1R56HL169891-01 · under PAR-21-038JIANG, BINNORTHWESTERN UNIVERSITY AT CHICAGO, IL$502,949IVPP
2023Optically Promoting Cardiac Maturation Using Engineered Peptides1R01HL164348-01A1 · under PAR-21-038ARDOÑA, HERDELINE ANN MALLARIUNIVERSITY OF CALIFORNIA-IRVINE, CA$501,245BMBI
2023Investigating the neutrophil-sensory neuron crosstalk in lung cancer1R01CA280601-01 · under PAR-21-038JIN, CHENGCHENGUNIVERSITY OF PENNSYLVANIA, PA$500,985THI
2023Gain-of-function complement activators as a new class of immunotherapeutic molecules1R01CA269217-01A1 · under PAR-21-038MARTINEZ BARRICARTE, RUBENVANDERBILT UNIVERSITY MEDICAL CENTER, TN$495,105ZRG1
2023Generating Robust anti-HIV CD8 T cells using HIV-targeted Liposomal Vaccines1R56AI179226-01 · under PAR-21-038DEAK, PETERDREXEL UNIVERSITY, PA$485,892HIVD
2023Elucidating the Role of Multinuclearity in Healthy and Diseased Mammalian Cardiomyocytes1R01HL162636-01A1 · under PAR-21-038RAU, CHRISTOPH DANIELUNIV OF NORTH CAROLINA CHAPEL HILL, NC$485,720ZRG1
2023Biomechanics of muscle after rotator cuff tear: Multi-scale assessment of spatial and temporal effects1R01AR079999-01A1 · under PAR-21-038VIDT, MEGHAN ELISEPENNSYLVANIA STATE UNIV HERSHEY MED CTR, PA$464,598SMEP
2023Lymphatic support of neurogenesis and regeneration1R01NS126209-01A1 · under PAR-21-038HARRISON, MICHAELWEILL MEDICAL COLL OF CORNELL UNIV, NY$451,763ZRG1
2023Defining the cellular dynamics that orchestrate alveolar epithelial cell repair behaviors in live mammal1R01HL162629-01A1 · under PAR-21-038CHIOCCIOLI, MAURIZIOYALE UNIVERSITY, CT$436,350ZRG1
2023Wireless mechano-electrical stimulation of pudendal nerve using piezoelectric platform for stress urinary incontinence1R01DK135472-01 · under PAR-21-038UZ, METINCLEVELAND STATE UNIVERSITY, OH$435,189ZRG1
2023Developing a clinically-relevant genetically engineered mouse model for Nut carcinoma1R37CA269076-01A1 · under PAR-21-038GU, BINMICHIGAN STATE UNIVERSITY, MI$433,718MONC
2023Behavioral and neural mechanisms mediating social motivation in a rat model for ASD1R01MH129310-01A1 · under PAR-21-038VENNIRO, MARCOUNIVERSITY OF MARYLAND BALTIMORE, MD$432,962DBD
2023Developing a Synthetic Adeno-Associated Virus (AAV) for Engineering Safer Gene Therapies1R01NS131151-01 · under PAR-21-038SHTRAHMAN, MATTHEWUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$420,026MNG
2023Sympathetic Activation and Cerebrovascular Pressure Reactivity after Traumatic Brain Injury (TBI)1R01NS133245-01 · under PAR-21-038MORALEZ, GILBERTOPINTO, SHANTI MARIEUT SOUTHWESTERN MEDICAL CENTER, TX$407,151ANIE
2023HIGHLY SELECTIVE MACROBIOMOLECULAR ISOLATION, SOFT-LANDING AND CHARACTERIZATION USING STRUCTURES FOR LOSSLESS ION MANIPULATIONS1R01CA283818-01 · under PAR-21-038GARIMELLA, SANDILYABATTELLE PACIFIC NORTHWEST LABORATORIES, WA$406,640ISD
2023Coordinated Heart Stimulation Testbed: A Platform for Contractile Ventricle Engineering1R01HL169632-01 · under PAR-21-038HOCHMAN-MENDEZ, CAMILATEXAS HEART INSTITUTE, TX$404,238BMBI
2023Looking through the bottle: Exploring alcohol use among emergency medical service providers1R01AA030975-01 · under PAR-21-038KOEPPEL, MARIANDRI-USA, INC., NY$399,326ARM
2023Investigating pulmonary complications due to abnormal collagen/ER stress in Osteogenesis Imperfecta1R01HL160554-01A1 · under PAR-21-038ZIEBA, JENNIFERUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$390,000LIRR
2023MAIT cells in lupus skin disease and photosensitivity1R01AR080641-01A1 · under PAR-21-038SKOPELJA-GARDNER, SLADJANADARTMOUTH-HITCHCOCK CLINIC, NH$387,047HAI
2023Studies of SLC41A1, a Mg2+-Transporting Protein Linked to Parkinson's Disease1R01NS126211-01A1 · under PAR-21-038ZUBCEVIC, LEJLAUNIVERSITY OF KANSAS MEDICAL CENTER, KS$384,200BBM
2023Volumetric imaging and computation to characterize cardiac electromechanical coupling1R01HL162635-01A1 · under PAR-21-038DING, YICHENUNIVERSITY OF TEXAS DALLAS, TX$383,914MPPB
2023Role of Metallothionein 1 E in the protection of cystic fibrosis-related diabetes1R01DK136624-01 · under PAR-21-038JI, XIANGMINGGEORGIA STATE UNIVERSITY, GA$382,590ZRG1
2023Improving glioma radiotherapy by theragnostic targeting of tumor-supporting macrophages1R01NS131160-01 · under PAR-21-038SCARPELLI, MATTHEWPURDUE UNIVERSITY, IN$381,494RTB
2023Regulation of prostate organogenesis by tissue-resident macrophages1R01DK134311-01 · under PAR-21-038SHIBATA, MAHOGEORGE WASHINGTON UNIVERSITY, DC$355,300KUFD
2023Subcellular-targeted CYP2E1 and alcohol in the brain1R01AA029664-01A1 · under PAR-21-038HARTMAN, JESSICA HELENEMEDICAL UNIVERSITY OF SOUTH CAROLINA, SC$354,458NAL
2023Avoiding Cesarean-induced Obesity Through Hormone Rescue1R01HD111737-01 · under PAR-21-038KENKEL, WILLIAMUNIVERSITY OF DELAWARE, DE$345,830POMD
2023Platelet-mitochondria transplantation to treat mitochondrial dysfunction in acute kidney injury1R01DK135470-01 · under PAR-21-038BOUCHAREB, RIHABICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY$338,000PBKD
2023An Engineered Surface of Mucociliary Transport for Medical Devices1R01EB033395-01A1 · under PAR-21-038XIE, YULIANGUNIVERSITY OF IOWA, IA$319,029ISD
20233D Engineered Model of Microscopic Colorectal Cancer Liver Metastasis for Adjuvant Chemotherapy Screens1R37CA269224-01A1 · under PAR-21-038RAGHAVAN, SHREYATEXAS ENGINEERING EXPERIMENT STATION, TX$316,749CMT
2023Regulation of Synaptic Rhythmicity by Astrocytic Clock1R01NS133047-01 · under PAR-21-038FARHY, ISABELLATEXAS A&M UNIVERSITY, TX$294,726BNRS
2023ModRNA-based Direct Programming of Universal Donor hiPSCs into Immune Evasive Beta Cells1R56DK133147-01A1 · under PAR-21-038LIAN, XIAOJUNPENNSYLVANIA STATE UNIVERSITY, THE, PA$240,478CMT
2022Role of RhCMV in shaping the SIV proviral landscape1R01AI167644-01 · under PAR-21-038MUDD, JOSEPH CHRISTOPHERTULANE UNIVERSITY OF LOUISIANA, LA$850,728HIVD
2022A high sensitivity gamma camera using a combination of Compton reconstruction and source proximity for in-vivo imaging of Ac-2251R01EB032324-01A1 · under PAR-21-038CARAVACA, JAVIERUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$821,522ITD
2022Quantitative Endogenous MRI Imaging of Neuroinflammation in AD1R01AG074909-01 · under PAR-21-038WANG, QINGWASHINGTON UNIVERSITY, MO$781,126EITN
2022Vasculopathy and Systemic Sclerosis-Associated Interstitial Lung Disease1R01HL164758-01 · under PAR-21-038BERNSTEIN, ELANACOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$751,586RIBT
2022Development of a Multi-scale closed loop model for hemorrhagic shock: a platform to assess REBOA performance1R01HL162633-01 · under PAR-21-038RAHBAR, ELAHEHWAKE FOREST UNIVERSITY HEALTH SCIENCES, NC$749,182BTSS
2022Mechanisms driving acute and chronic kidney function decline after immune checkpoint inhibitor therapy for cancer1R01DK130839-01 · under PAR-21-038SISE, MEGHAN E.MASSACHUSETTS GENERAL HOSPITAL, MA$726,788PBKD
2022EpiMoRPH: A simulation environment for generating spatially-refined intervention strategies for the control of infectious disease1R01AI168144-01 · under PAR-21-038MIHALJEVIC, JOSEPHNORTHERN ARIZONA UNIVERSITY, AZ$724,855BMRD
2022Impact of Early-life Exposure to Semi-Volatile Organic Compounds (SVOCs) on Neonatal and Early Childhood Immune Function1R01AI167850-01 · under PAR-21-038HOFFMAN, JENNIFER KDUKE UNIVERSITY, NC$716,067ZRG1
2022Immunogenomic analysis of donor lung injury and its impact on clinical outcomes after lung transplantation1R01HL160551-01A1 · under PAR-21-038SHAVER, CIARA MVANDERBILT UNIVERSITY MEDICAL CENTER, TN$709,322LIRR
2022Developmental Origins of Cardiovascular Disease in Offspring from Non-human Primate Pregnancies at Advanced Maternal Age1R56HL164434-01 · under PAR-21-038CILVIK, SARAH NWAKE FOREST UNIVERSITY HEALTH SCIENCES, NC$708,146PN
2022Gut bacterial metallophores in the development and severity of inflammatory bowel disease1R01DK131990-01 · under PAR-21-038SAMUELSON, DERRICK RUNIVERSITY OF NEBRASKA MEDICAL CENTER, NE$693,330XNDA
2022Worldwide Mapping of Air Pollution Exposure Patterns on Aging Brain Health1R01ES033961-01 · under PAR-21-038SALMINEN, LAUREN E.UNIVERSITY OF SOUTHERN CALIFORNIA, CA$662,575CNN
2022Evaluating the rehabilitative potential of tactile number expressions for multisensory vision and hearing loss using wearable haptics1R01EY033761-01 · under PAR-21-038GAGNE, DEANNAGALLAUDET UNIVERSITY, DC$649,543HCMF
2022Scalable Biomarkers and Generative Digital Twins for Personalized Neurostimulation in Depression1R01MH131534-01 · under PAR-21-038GROSENICK, LOGANWEILL MEDICAL COLL OF CORNELL UNIV, NY$634,277NPAS
2022Improved MRI guidance of pediatric catheterization via autonomous multi-beat data synthesis1R01HL162671-01 · under PAR-21-038CONTIJOCH, FRANCISCO JUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$627,572IGIS
2022Quantitative Language and Facial Expression Phenotyping of Chronic Pain1R01AR080627-01A1 · under PAR-21-038GEHA, PAULUNIVERSITY OF ROCHESTER, NY$609,468BMHO
2022Discovery and manipulation of transcription factors to restore long term stem cell repopulation in aged bone-marrow1R01AG074932-01 · under PAR-21-038ABUDAYYEH, OMAR OGOOTENBERG, JONATHAN SAMUELMASSACHUSETTS INSTITUTE OF TECHNOLOGY, MA$601,926CMAD
2022Intra- and Intergenerational Consequences of Maternal Stress Exposure for Maternal-Infant Health in Black U.S. Families1R01HD106913-01 · under PAR-21-038LIN, BETTYSTATE UNIVERSITY OF NEW YORK AT ALBANY, NY$600,026MESH
2022Bacterial adaptions in host-microbe interactions.1R01AI167860-01 · under PAR-21-038CHU, HIUTUNGUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$589,629DHMI
2022Microbial reactivation of sex steroids and visceral pain1R01DK130836-01A1 · under PAR-21-038RAO, MEENAKSHIBOSTON CHILDREN'S HOSPITAL, MA$589,168DNPD
2022Dissecting dynamic genetic effects from thymus development to immune-mediated disease1R01AI167862-01 · under PAR-21-038MEYER, HANNAH VERENACOLD SPRING HARBOR LABORATORY, NY$587,919GHD
2022Autophagon: an Autophagy-Functionalizing Gene Therapy Tool for Neurodegenerative Diseases1R01AG074899-01 · under PAR-21-038YAKOUB, ABRAAM M.UNIVERSITY OF NORTH DAKOTA, ND$568,004NOMD
2022TSPO-PET and MRI imaging as novel imaging tools for autoimmune epilepsy1R01NS126156-01 · under PAR-21-038STERIADE, CLAUDENEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY$561,887ANIE
2022Effect of Renal Nerves on Chronic Kidney Disease1R01DK131991-01 · under PAR-21-038TAN, RODERICK JASONUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$542,541PBKD
2022Role of Testosterone in Modulating Tau Pathogenesis in Females1R01AG078185-01 · under PAR-21-038CHEN, XUUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$534,810CDIN
2022New models, new approaches, new horizons in corneal nerve regeneration1R01EY033291-01 · under PAR-21-038LEE, VIVIANUNIVERSITY OF PENNSYLVANIA, PA$511,695PED1
2022The role of distributional reinforcement learning in human neurons during impulsive choices1R01MH128187-01 · under PAR-21-038SMITH, ELLIOT HUNIVERSITY OF UTAH, UT$509,811HCMF
2022Role of the FAAH-OUT locus in cutaneous wound healing1R01AR079992-01 · under PAR-21-038SUN, BRYANUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$506,648ACTS
2022Neural mechanisms underlying the sensitive period for phonetic learning in infants at-risk for Developmental Language Disorder1R01DC020419-01 · under PAR-21-038ZHAO, TIANUNIVERSITY OF WASHINGTON, WA$496,762LCOM
2022Optically Promoting Cardiac Maturation Using Engineered Peptides1R56HL164348-01 · under PAR-21-038ARDOÑA, HERDELINE ANN MALLARIUNIVERSITY OF CALIFORNIA-IRVINE, CA$494,946BMBI
2022Role of the CD47 Pathway in Rheumatoid Arthritis Pathogenesis and Treatment1R01AR080015-01A1 · under PAR-21-038KORMAN, BENJAMIN DOUGLASUNIVERSITY OF ROCHESTER, NY$493,761ACTS
2022Biofilm Spatial Structure in the Transition from Health to Periodontal Disease1R01DE031213-01 · under PAR-21-038VALM, ALEX MSTATE UNIVERSITY OF NEW YORK AT ALBANY, NY$477,738ODCS
2022Therapeutic bubble tea: Preventing the formation of uremic toxins with hydrogel immobilized microbes1R01DK130815-01 · under PAR-21-038WINKLER, MARI-KAROLIINAUNIVERSITY OF WASHINGTON, WA$475,802XNDA
2022Immunomodulatory Therapy After Resuscitation From Cardiac Arrest1R01HL160538-01 · under PAR-21-038WEIL, BRIAN RAYMONDSTATE UNIVERSITY OF NEW YORK AT BUFFALO, NY$455,629ZRG1
2022Engineered Asymmetric Hydrogel for Muscle Stem Cell Polarity and Fate Specification1R01AR080616-01 · under PAR-21-038HAN, WOOJINICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY$455,368BMBI
2022Defining cellular mechanisms of chronic graft failure in transplanted hearts with single cell multi-omics1R01HL160552-01 · under PAR-21-038GAO, RULINORTHWESTERN UNIVERSITY AT CHICAGO, IL$434,154BBHV
2022Novel molecular mechanism for extracellular release of proteins implicated in metastatic cancer1R37CA265877-01A1 · under PAR-21-038DASTVAN, REZASAINT LOUIS UNIVERSITY, MO$430,794BBM
2022Alcohol-induced Gut Dysbiosis and Cardiovascular Disease1R01AA029984-01 · under PAR-21-038SHARP, THOMAS E.LSU HEALTH SCIENCES CENTER, LA$429,615ZRG1
2022Growth differentiation factor-15 (GDF15) as a novel myocardial hormone in heart failure1R01HL160589-01 · under PAR-21-038BURKE, MICHAEL AEMORY UNIVERSITY, GA$428,225MPPA
2022Evaluating the Impact of Restrictive Eating Disorders on White Matter Development1R01MH130781-01 · under PAR-21-038LYALL, AMANDA ELLISMASSACHUSETTS GENERAL HOSPITAL, MA$420,000NPAS
2022Developing splicing-targeted therapeutic strategies for neurological diseases1R01NS124561-01A1 · under PAR-21-038MORINI, ELISABETTATELO BAPTISTA LIMA DA SILVA, MARIA CATARINAMASSACHUSETTS GENERAL HOSPITAL, MA$420,000TAG
2022Defining Novel Cardiovascular Mechanisms For TKI Induced Excitability1R01HL160590-01A1 · under PAR-21-038SMITH, SAKIMA AHMADOHIO STATE UNIVERSITY, OH$412,779MPPB
2022Orbitofrontal circuit mechanisms underlying alcohol use disorder1R01AA029661-01A1 · under PAR-21-038K NAMBOODIRI, VIJAY MOHANUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$410,901NAL
2022Investigation of self-nucleic acids as a trigger for neuroinflammation1R01NS127802-01 · under PAR-21-038CHUNG, HACHUNGCOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$409,161CMND
2022Epigenetic mechanisms contributing to the pathogenesis of ALS/FTD with GGGGCC repeat expansion mutation at the C9orf72 locus1R01NS126185-01 · under PAR-21-038LIU, X. SHAWNCOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$406,218CMND
2022The role of hearing loss in cognitive impairment and Alzheimer’s disease pathology1R01AG078132-01 · under PAR-21-038BIGELOW, JAMESUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$403,750ZRG1
2022Role of disrupted polyamine synthesis during CKD-MBD related bone loss1R01DK130866-01 · under PAR-21-038CLINKENBEARD, ERICA LINDIANA UNIVERSITY INDIANAPOLIS, IN$402,119SBDD
2022Predicting risk of systemic autoimmune disease in patients with positive antinuclear antibodies1R01AR080629-01 · under PAR-21-038BARNADO, APRIL LYNNVANDERBILT UNIVERSITY MEDICAL CENTER, TN$400,690CDMA
2022Multi-scale functional connectivity in preclinical models of Parkinson's disease1R01NS124575-01 · under PAR-21-038STOKES, ASHLEY MST. JOSEPH'S HOSPITAL AND MEDICAL CENTER, AZ$399,380EITN
2022Metabolic reprogramming and FGF21 signaling in kidney health and polycystic kidney diseases1R01DK133118-01 · under PAR-21-038DAI, DAO-FUUNIVERSITY OF IOWA, IA$396,609PBKD
2022Restoring immune-vascular axis integrity to alleviate acute lung injury in sepsis1R56HL160545-01A1 · under PAR-21-038PAL, KRISHNENDUMAYO CLINIC JACKSONVILLE, FL$391,250RIBT
2022Circuit Mechanisms of Psilocybin Following Chronic Stress1R01MH129282-01 · under PAR-21-038AHMED, OMAR JAMILUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$390,000PMDA
2022Control of extracellular matrix remodeling by CD29+ astrocytes1R01MH130458-01 · under PAR-21-038WHEELER, MICHAEL ALEXBRIGHAM AND WOMEN'S HOSPITAL, MA$384,652CMBG
2022Defining proteostasis networks in axon segments1R01NS127781-01 · under PAR-21-038SUMMERS, DANIELUNIVERSITY OF IOWA, IA$373,732NDPR
2022Evaluation techniques for mHealth outcome measures using patient generated health data1R01HD108263-01 · under PAR-21-038ENSARI, IPEKICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY$371,673CIDH
2022Cerebellar granule cell dysfunction in Shank3 mutant mice1R01MH129749-01 · under PAR-21-038RICHARDSON, BEN DSOUTHERN ILLINOIS UNIVERSITY SCH OF MED, IL$368,750ZRG1
2022Biocompatible triarylmethyl radical-based dendrimers as nonmetallic contrast agents for MRI1R01EB032321-01A1 · under PAR-21-038DRIESSCHAERT, BENOITWEST VIRGINIA UNIVERSITY, WV$366,759ZRG1
2022A deep learning and experiment integrated platform for stable mRNA vaccines development1R01AI165433-01 · under PAR-21-038SUN, QINGTEXAS ENGINEERING EXPERIMENT STATION, TX$361,174MSFD
2022Molecular mechanisms of mechanosensation in the cardiac pacemaker1R01HL162609-01 · under PAR-21-038MORENO, CLAUDIA MARCELAUNIVERSITY OF WASHINGTON, WA$361,000MPPB
2022Engineer Biomimetic Microfluidic Models to Investigate and Reprogram Tumor Associated Neutrophils for Cancer Therapy1R37CA265926-01A1 · under PAR-21-038BAO, XIAOPINGPURDUE UNIVERSITY, IN$358,885ZRG1
2022Tracheobronchitis in the Critically Ill1R01HL162964-01 · under PAR-21-038ZEMKE, ANNA CHRISTINEUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$353,096IRAP
2022A gut-brain interaction controlling reward learning1R01DK133823-01 · under PAR-21-038HOWE, WILLIAM MATTHEWVIRGINIA POLYTECHNIC INST AND ST UNIV, VA$352,436NMB
2022Sex differences in microglia-neuron-circuit interactions in adolescence1R01MH128176-01 · under PAR-21-038HAMM, JORDAN PGEORGIA STATE UNIVERSITY, GA$345,200ZRG1
2022Identifying the relationship between alcohol and Alzheimer's Disease1R01AA029985-01 · under PAR-21-038KIMBROUGH, ADAM JPURDUE UNIVERSITY, IN$343,345NAL
2022Exploiting Alzheimer's disease patient-derived stem cells to biochemically define tau and amyloid-beta oligomer toxic features and their downstream cellular effects1R01AG078187-01 · under PAR-21-038O'NEIL, ALISON LINSLEYWESLEYAN UNIVERSITY, CT$328,600ZRG1
2022Understanding alterations to mucus composition and function in asthma1R01HL160540-01A1 · under PAR-21-038DUNCAN, GREGGUNIV OF MARYLAND, COLLEGE PARK, MD$305,451LCMI
2022Role of Angiotensin II in Bladder Dysfunction1R01DK132003-01A1 · under PAR-21-038MICKLE, AARON DAVIDUNIVERSITY OF FLORIDA, FL$296,011KUFD
2022Leveraging Mammalian Cancers, Platinum-Quality Genome Assemblies, and Large-Scale Data to Identify Mechanisms of Rare Human Cancers1R01CA265907-01 · under PAR-21-038GRAIM, KILEYUNIVERSITY OF FLORIDA, FL$248,259BDMA
2022Defining and Manipulating the Endothelial Niche in Myelodysplastic Syndromes1R01DK133131-01 · under PAR-21-038BAJAJ, JEEVISHAUNIVERSITY OF ROCHESTER, NY$231,000HTBT
2021Mechanisms of innate immune dysfunction in SIV/malaria co-infection in pregnancy1R01HD108015-01 · under PAR-21-038MANUZAK, JENNIFERTULANE UNIVERSITY OF LOUISIANA, LA$842,028HCCS
2021HIV antibodies and NK cell ADCC: nanometer-scale tracking of immune synapse dynamics.1R01AI167646-01 · under PAR-21-038MURIN, CHARLES DANIELSCRIPPS RESEARCH INSTITUTE, THE, CA$448,592HIVD

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