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NIH funding notice PAR-24-100

NIAID Clinical Trial Implementation Cooperative Agreement (U01 Clinical Trial Required)

Closed on May 23, 2025.

Posted
January 29, 2024
Close date
May 23, 2025
Activity codes
U01
Institutes taking part
NIAID

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

  1. Reissues: PAR-21-083 NIAID Clinical Trial Implementation Cooperative Agreement (U01 Clinical Trial Required)
  2. 2 steps back: PAR-18-633 NIAID Clinical Trial Implementation Cooperative Agreement (U01 Clinical Trial Required)
  3. 3 steps back: PAR-16-270 NIAID Clinical Trial Implementation Cooperative Agreement (U01)
  4. 4 steps back: PAR-13-151 NIAID Clinical Trial Implementation Cooperative Agreement (U01)
  5. 5 steps back: PAR-11-234 NIAID Clinical Trial Implementation Cooperative Agreement (U01)
  6. 6 steps back: PAR-10-186 NIAID Clinical Trial Implementation Cooperative Agreement (U01)
  7. 7 steps back: PAR-05-113 NIAID Clinical Trial Implementation (U01) Cooperative Agreement

Replaced by PAR-27-064.

Who won it before

99 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $117,984,150 in first-year total cost, median $1,088,316.

Most frequent study sections

  1. Special Emphasis Panel[ZAI1 MFH-M (M1)]7
  2. Special Emphasis Panel[ZAI1 LG-M (M1)]5
  3. Special Emphasis Panel[ZAI1 BLG-M (M1)]3
  4. Special Emphasis Panel[ZAI1 MSA-M (J1)]3
  5. Special Emphasis Panel[ZAI1 PA-I (M1)]3

Most frequent institutions

  1. UNIVERSITY OF CALIFORNIA, SAN FRANCISCO10
  2. JOHNS HOPKINS UNIVERSITY8
  3. BOSTON CHILDREN'S HOSPITAL6
  4. VANDERBILT UNIVERSITY MEDICAL CENTER6
  5. UNIVERSITY OF PITTSBURGH AT PITTSBURGH5
Competing awards under PAR-24-100 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2025Combating Related Epidemics in HCV through Simplified Testing and Treatment (CREST)1U01AI195193-01NAGGIE, SUSANNADUKE UNIVERSITY, NC$3,411,692ZAI1
2025Expanding HOPE Liver Transplantation: Understanding Opportunistic Infection and Cancer Risk2U01AI138897-06A1DURAND, CHRISTINE MARIESEGEV, DORRY L.TOBIAN, AARON AJOHNS HOPKINS UNIVERSITY, MD$1,683,861ZAI1
2025Phase 1 study of a SARS-CoV-2 vaccine adjuvanted via controlled biodistribution of mRNA encoding spike protein and IL-12p701U01AI191995-01BADEN, LINDSEY ROBERTDOWLING, DAVID JAMESBOSTON CHILDREN'S HOSPITAL, MA$1,673,641ZAI1
2025Phase 1 Randomized Double-Blind Placebo-Controlled Safety Study of MucoCept-CVN (Lactobacillus jensenii 1153-1666) Administered Vaginally to Healthy Women1U01AI186333-01 · under PAR-21-083COHEN, CRAIG RHEMMERLING, ANKEUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$1,533,177ZAI1
2025SMART Use of Biologics in Chronic Rhinosinusitis with Nasal Polyposis1U01AI181696-01A1MULLIGAN, JENNIFER KONOPASMITH, TIMOTHY LSOLER, ZACHARY MOREGON HEALTH & SCIENCE UNIVERSITY, OR$1,498,642ZAI1
2025EARLY SIGNALS OF THE TRANSITION FROM IMMUNE QUIESCENCE TO ACTIVATION IN THE LIVER ALLOGRAFT MICROENVIRONMENT AND IN THE CIRCULATION1U01AI189341-01FENG, SANDYUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$1,468,517ZAI1
2025Gene therapy for SCID-X1 with low dose busulfan and a SIN-lentiviral vector2U01AI125051-08WILLIAMS, DAVID ABOSTON CHILDREN'S HOSPITAL, MA$1,305,361ZAI1
2025Re-evaluating the Duration in Children of TB Treatment (REDUCE TB): A Phase 2 Duration Randomized Trial1U01AI192041-01GARCIA-PRATS, ANTHONY JOSEPHUNIVERSITY OF WISCONSIN-MADISON, WI$1,286,549ZAI1
2025Molecular determinants of vaccine-induced antibody durability1U01AI189332-01A1LEWIS, GEORGE KSAJADI, MOHAMMAD MOHSENIUNIVERSITY OF MARYLAND BALTIMORE, MD$777,495ZAI1
2025The impact of shigellosis and recommended treatment in children1U01AI179562-01A1CHAKRABORTY, SUBHRAJOHNS HOPKINS UNIVERSITY, MD$762,838ZAI1
2025A Phase 2b randomized open label trial to assess the quality and balance of dengue immunity elicited by prime-boost combinations of TAK-003 and Butantan-DV1U01AI186860-01A1COLLINS, MATTHEWEDUPUGANTI, SRILATHATEIXEIRA, MAURO MEMORY UNIVERSITY, GA$578,157ZAI1
2025STeroids and enhanced Antibiotics for the treatment of patients in Africa with Refractory Sepsis: STARS trial1U01AI192033-01HEYSELL, SCOTT KMOORE, CHRISTOPHER CHARLESUNIVERSITY OF VIRGINIA, VA$361,931ZAI1
2025Cluster randomized trial of intermittent preventive treatment of malaria in school-agechildren to improve the health of students and decrease community transmission(CRITICal)1U01AI186861-01 · under PAR-21-083DORSEY, MATTHEW GNANKABIRWA, JOANITER IMMACULATEUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$152,474ZAI1
2024Optimizing the diagnostic approach to cephalosporin allergy testing (DACAT Trial)1U01AI184071-01 · under PAR-21-083BLUMENTHAL, KIMBERLY GOLDKHAN, DAVID AMASSACHUSETTS GENERAL HOSPITAL, MA$3,234,536ZAI1
2024Controlling and Preventing Asthma Progression and Severity in Kids with Omalizumab Extension (PARK-EXT)1U01AI179563-01 · under PAR-21-083PHIPATANAKUL, WANDABOSTON CHILDREN'S HOSPITAL, MA$2,250,000ZAI1
2024A Phase 1/2a, randomized study of a Tfh-targeting genetic vaccine adjuvant designed to induce broad, durable immune responses1U01AI172800-01A1 · under PAR-21-083CHEW, KARA WDEEKS, STEVEN GRANTHARTIGAN-O'CONNOR, DENNIS J.UNIVERSITY OF CALIFORNIA LOS ANGELES, CA$1,435,214ZAI1
2024Dupilumab in the Treatment of Pediatric Alopecia Areata1U01AI179629-01 · under PAR-21-083GUTTMAN, EMMAICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY$1,419,216ZAI1
2024A Phase II Controlled Trial of Allogeneic Mesenchymal Stromal Cells for the Treatment of Refractory Lupus (MiSLE)1U01AI184159-01 · under PAR-21-083GILKESON, GARY SKAMEN, DIANE LMEDICAL UNIVERSITY OF SOUTH CAROLINA, SC$1,225,013ZAI1
2024Clinical and mechanistic studies defining optimal preparative approaches to infants with IL2RG/JAK3/RAG1/RAG2 SCID: a randomized trial of busulfan dosage1U01AI184132-01 · under PAR-21-083AULETTA, JEFFERY JPULSIPHER, MICHAEL ANATIONAL MARROW DONOR PROGRAM, MN$1,072,951ZAI1
2024A Phase II Study Evaluating the Safety and Efficacy of Whole-Cell Pneumococcal Vaccine (wSp) in Reducing Nasopharyngeal Colonization by Streptococcus pneumoniae in Young Children1U01AI172733-01A1 · under PAR-21-083PICHICHERO, MICHAEL EROCHESTER GENERAL HOSPITAL (NY), NY$822,233ZAI1
2023Comparison of High vs. Standard Dose Influenza Vaccine in Pediatric Solid Organ Transplant Recipients1U01AI167799-01A1 · under PAR-21-083DANZIGER-ISAKOV, LARA AHALASA, NATASHA BASSAMVANDERBILT UNIVERSITY MEDICAL CENTER, TN$1,815,533ZAI1
2023A Clinical Trial of Three Broadly Neutralizing Antibodies and Analytic Treatment Interruption in Early-Treated Children in Botswana1U01AI179561-01 · under PAR-21-083KURITZKES, DANIEL R.LICHTERFELD, MATHIASSHAPIRO, ROGER LHARVARD SCHOOL OF PUBLIC HEALTH, MA$1,799,067ZAI1
2023Kidney Transplantation from Donors with HIV: Impact on Rejection and Long-term Outcomes1U01AI177211-01 · under PAR-21-083DURAND, CHRISTINE MARIESEGEV, DORRY L.JOHNS HOPKINS UNIVERSITY, MD$1,781,226ZAI1
2023Safety and efficacy of Belatacept in heart transplantation1U01AI174997-01 · under PAR-21-083HABAL, MARLENANEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY$1,775,433ZAI1
2023Optimizing the dose of tafenoquine for the radical cure of Plasmodium vivax malaria in Southeast Asia1U01AI165321-01A1 · under PAR-21-083CHU, CINDY SUNIVERSITY OF OXFORD$1,067,899ZAI1
2023First-in-human study of a potent anti-HBsAg neutralizing antibody1U01AI167786-01A1 · under PAR-21-083CASKEY, MARINAROCKEFELLER UNIVERSITY, NY$864,658ZAI1
2023Randomized Control Trial of Nitazoxanide for the Treatment of Cryptosporidium Infection in Malnourished Children in Bangladesh1U01AI167788-01A1 · under PAR-21-083KORPE, POONUM S.JOHNS HOPKINS UNIVERSITY, MD$777,454ZAI1
2023Enhanced Antifungal Therapy to Improve Survival in Early Disseminated Cryptococcal Infection1U01AI174978-01 · under PAR-21-083RAJASINGHAM, RADHAUNIVERSITY OF MINNESOTA, MN$676,872ZAI1
2023A multicenter, randomized controlled trial of single and multiple dose regimes of oxfendazole for mild (one or two lesions) parenchymal brain cysticercosis1U01AI177191-01 · under PAR-21-083GARCIA, HECTOR HUGOUNIVERSIDAD PERUANA CAYETANO HEREDIA$514,732ZAI1
2023A Non-Inferiority Randomized Single Blind Controlled Trial Comparing One and Two Dose Regimes of Oxfendazole versus a Two Dose Regime of Triclabendazole to Treat Chronic Fascioliasis1U01AI155323-01A1 · under PAR-18-633CABADA, MIGUEL MAURICIOGARCIA, HECTOR HUGOUNIVERSIDAD PERUANA CAYETANO HEREDIA$439,115ZAI1
2022Improving Neonatal health Through Rapid malaria testing in Early Pregnancy with high-sensitivity Diagnostics (INTREPiD)1U01AI162463-01A1 · under PAR-21-083TAYLOR, STEVE MYERDUKE UNIVERSITY, NC$1,407,688ZAI1
2022Focal mass drug administration (fMDA) to reduce Plasmodium vivax transmission, a pragmatic cluster randomized controlled trial in Peru1U01AI157962-01A1 · under PAR-21-083HSIANG, MICHELLE SANGUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$1,293,493ZAI1
2022PRESCIENT: A phase IIc, open-label, randomized controlled trial of ultra-short course bedaquiline, clofazimine, pyrazinamide and delamanid versus standard therapy for drug-susceptible tuberculosis1U01AI170426-01 · under PAR-21-083KOENIG, SERENA PATRICIAWASSERMAN, SEAN ADAMBRIGHAM AND WOMEN'S HOSPITAL, MA$1,221,014ZAI1
2022Mechanistic clinical trial of blocking the IL-4/13 axis in asthmatics precision phenotyped in an aeroallergen challenge chamber before, during and after receipt of dupilumab1U01AI158460-01A1 · under PAR-21-083AHUJA, SUNIL KUNIVERSITY OF TEXAS HLTH SCIENCE CENTER, TX$1,182,367ZAI1
2022A Randomized Controlled Trial of Prophylaxis with Direct-acting Antivirals for Kidney Transplantation from Hepatitis C virus-infected donor to Uninfected Recipients (PREVENT-HCV)1U01AI157931-01A1 · under PAR-21-083DURAND, CHRISTINE MARIESEGEV, DORRY L.JOHNS HOPKINS UNIVERSITY, MD$1,025,696ZAI1
2022Long-term health and socioeconomic impact of interventions targeting low-density malaria infection (LMI) among children in Tanzania1U01AI155315-01A1 · under PAR-18-633HSIANG, MICHELLE SANGUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$936,110ZAI1
2022Comparison of High Dose vs. Standard Dose Influenza Vaccines in Lung Allograft Recipients1U01AI167789-01 · under PAR-21-083HALASA, NATASHA BASSAMVANDERBILT UNIVERSITY MEDICAL CENTER, TN$913,378ZAI1
2022Safety and Immunogenicity of novel, live-attenuated V4020 vaccine for Venezuelan Equine Encephalitis (VEE) in healthy adults1U01AI155406-01A1 · under PAR-18-633PUSHKO, PETER M.MEDIGEN, INC., MD$709,235ZAI1
2022Supplemental Citicoline Administration for Reduction of Lung Injury Efficacy Trial (SCARLET)1U01AI167784-01 · under PAR-21-083CROUSER, ELLIOTT DDAVIS, IAN CHRISTOPHEROHIO STATE UNIVERSITY, OH$576,575ZAI1
2021Glucagon-Like Peptide-1 Receptor Agonist Treatment in Adult, Obesity-Related, Symptomatic Asthma1U01AI155299-01 · under PAR-18-633BERNARD, GORDON RAPHAELCAHILL, KATHERINE NVANDERBILT UNIVERSITY MEDICAL CENTER, TN$1,583,667ZAI1
2021Enhancing immunity to malaria in young children with effective chemoprevention1U01AI155325-01A1 · under PAR-18-633JAGANNATHAN, PRASANNASTANFORD UNIVERSITY, CA$1,283,030ZAI1
2021DON in Pediatric Cerebral Malaria: A Phase I / II Dose-Escalation Safety Study1U01AI155300-01A1 · under PAR-18-633POSTELS, DOUGLASCHILDREN'S RESEARCH INSTITUTE, DC$1,088,316ZAI1
2021Efficacy of immunization with 4C-MenB in preventing experimental urethral infection with Neisseria gonorrhoeae.1U01AI162457-01 · under PAR-18-633DUNCAN, JOSEPH AHOBBS, MARCIA METZGARUNIV OF NORTH CAROLINA CHAPEL HILL, NC$809,476ZAI1
2021Dietary and synbiotic strategy to limit gut microbiome dysbiosis and protect against Clostridioides difficile infection1U01AI150589-01A1 · under PAR-18-633LOZUPONE, CATHERINEUNIVERSITY OF COLORADO DENVER, CO$776,329ZAI1
2021Randomized trial of viral specific T-cell infusion to prevent viral infection after hematopoietic stem cell transplant.1U01AI157620-01 · under PAR-18-633DAVIES, STELLA MARGARETLUTZKO, CAROLYN MCINCINNATI CHILDRENS HOSP MED CTR, OH$663,928ZAI1
2020A Multisectoral Strategy to Address Persistent Drivers of the HIV Epidemic in East Africa1U01AI150510-01A1 · under PAR-18-633HAVLIR, DIANE VKAMYA, MOSES ROBERTPETERSEN, MAYA LIVUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$4,526,307ZAI1
2020Bacteriophage-based approach for managing Shigella infections1U01AI148054-01 · under PAR-18-633CHEN, WILBUR H.FRASER, CLAIRE M.KOTLOFF, KAREN L.SULAKVELIDZE, ALEXANDERINTRALYTIX, INC., MD$1,952,644ZAI1
2020INSPIRE (INtelligent Stewardship Prompts to Improve Real-time Empiric Antibiotic Selection for Patients): The INSPIRE-ASP Trial for Intra-Abdominal and Skin and Soft Tissue Infections1U01AI153005-01 · under PAR-18-633HUANG, SUSAN S.PLATT, RICHARDHARVARD PILGRIM HEALTH CARE, INC., MA$1,646,462ZAI1
2020DRAMATIC Phase 2 Duration Randomized MDR-TB Treatment Trial1U01AI152980-01 · under PAR-18-633HORSBURGH, CHARLES ROBERTNAHID, PAYAMUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$1,470,699ZAI1
2020Initial clinical evaluation of attenuated Shigella flexneri 2a live vector expressing enterotoxigenic Escherichia coli antigens, strain CVD 1208S-122.1U01AI143493-01A1 · under PAR-18-633BARRY, EILEEN M.CHEN, WILBUR H.UNIVERSITY OF MARYLAND BALTIMORE, MD$1,391,457ZAI1
2020Quanitifying the Epidemiological Impact of Targeted Indoor Residual Spraying on Aedes-borne Diseases1U01AI148069-01 · under PAR-18-633VAZQUEZ PROKOPEC, GONZALO MARTINEMORY UNIVERSITY, GA$1,385,938ZAI1
2020Safety and Immunogenicity of H3N2 M2SR monovalent influenza vaccine in older subjects1U01AI141310-01A1 · under PAR-18-633BILSEL, PAMUKFLUGEN, INC., WI$1,311,111ZAI1
2020Optimal chemopreventive regimens to prevent malaria and improve birth outcomes in Uganda1U01AI141308-01A1 · under PAR-18-633DORSEY, MATTHEW GROSENTHAL, PHILIP JONUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$1,194,675ZAI1
2020Native-like Envelope Trimer Therapeutic Vaccination for Induction of Broadly Neutralizing Antibodies to Facilitate HIV Functional Cure1U01AI152969-01 · under PAR-18-633RIDDLER, SHARONUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$1,173,561ZAI1
2020Safety and Tolerability of Ultra-short Course Rifapentine and Isoniazid (1HP) for Prevention of Tuberculosis in HIV-Uninfected Individuals1U01AI152961-01 · under PAR-18-633CHAISSON, RICHARD E.JOHNS HOPKINS UNIVERSITY, MD$916,330ZAI1
2020Comparison of High vs. Standard Dose Influenza Vaccines in Adult Solid Organ Transplant Recipients1U01AI152967-01 · under PAR-18-633HALASA, NATASHA BASSAMVANDERBILT UNIVERSITY MEDICAL CENTER, TN$862,770ZAI1
2020A Phase I Randomized Clinical Trial of a Novel Mucosal Recombinant H5 Influenza Vaccine with Nanoemulsion Adjuvant Followed by Parenteral Boost of Licensed Inactivated Influenza A H5N1 Vaccine1U01AI148081-01 · under PAR-18-633ORTIZ, JUSTIN R.UNIVERSITY OF MARYLAND BALTIMORE, MD$769,127ZAI1
2020A randomized clinical trial of early empiric anti-Mycobacterium tuberculosis therapy for sepsis in sub-Saharan Africa1U01AI150508-01A1 · under PAR-18-633HEYSELL, SCOTT KMOORE, CHRISTOPHER CHARLESUNIVERSITY OF VIRGINIA, VA$682,830ZAI1
2019Intervention to Reduce Early (Peanut) Allergy in Children (iREACH)1U01AI138907-01A1 · under PAR-18-633GUPTA, RUCHI SLURIE CHILDREN'S HOSPITAL OF CHICAGO, IL$1,597,100ZAI1
2019Effect of IL-4RαR576 variant on response to Dupilumab in children with Asthma1U01AI143514-01 · under PAR-18-633CHATILA, TALAL AMINEPHIPATANAKUL, WANDABOSTON CHILDREN'S HOSPITAL, MA$1,458,175ZAI1
2019A Phase II Evaluation of the Safety and Protective Efficacy of the Live Attenuated Tetravalent Dengue Vaccine TetraVax-DV with Challenge by the Recombinant DENV-2 Virus in a Dengue Endemic Population1U01AI134582-01A1 · under PAR-18-633KIRKPATRICK, BETH DIANEUNIVERSITY OF VERMONT & ST AGRIC COLLEGE, VT$1,300,717ZAI1
2019Extended follow-up of randomized participants in the INSIGHT START trial1U01AI136780-01 · under PAR-16-270NEATON, JAMES DENNISUNIVERSITY OF MINNESOTA, MN$1,119,517ZHL1
2019"NextGen Long-acting Platform: Targeted Combination Antiretrovirals"1U01AI148055-01 · under PAR-18-633COLLIER, ANN CORNWALLHO, RODNEY J.Y.UNIVERSITY OF WASHINGTON, WA$794,929ZAI1
2019Trial of Metformin for TB/HIV Host-directed Therapy1U01AI134585-01A1 · under PAR-18-633KORNFELD, HARDYSINGHAL, AMITWALLIS, ROBERT SUNIV OF MASSACHUSETTS MED SCH WORCESTER, MA$571,971ZAI1
2018Targeting Inflammation and Alloimmunity in Heart Transplant Recipients with Tocilizumab1U01AI136816-01 · under PAR-16-270MADSEN, JOREN CMASSACHUSETTS GENERAL HOSPITAL, MA$3,029,663ZAI1
2018HOPE in Action: A Clinical Trial of HIV-to-HIV Liver Transplantation1U01AI138897-01 · under PAR-16-270DURAND, CHRISTINE MARIESEGEV, DORRY L.JOHNS HOPKINS UNIVERSITY, MD$1,778,541ZAI1
2018Short and long term outcomes of doxycycline versus TMP-SMX for SSTI treatment1U01AI116400-01A1 · under PAR-16-270MILLER, LOREN G.LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER, CA$1,186,965ZAI1
2018New chemotherapy regimens and biomarkers for Chagas disease1U01AI129783-01A1 · under PAR-16-270ALMEIDA, IGOR CGASCON, JOAQUIMTORRICO, FAUSTINOUNIVERSITY OF TEXAS EL PASO, TX$1,181,878ZAI1
2018Selective CD28 Blockade in Renal Transplant Recipients1U01AI138909-01 · under PAR-16-270ADAMS, ANDREW BFORD, MANDY LLARSEN, CHRISTIAN P.EMORY UNIVERSITY, GA$1,135,202ZAI1
2018Fecal Microbiota Transplant for C. difficile Infection in Solid Organ Transplant Recipients1U01AI125053-01A1 · under PAR-13-151SAFDAR, NASIAUNIVERSITY OF WISCONSIN-MADISON, WI$1,126,433ZAI1
2018Regulatory Dendritic Cell Therapy in Live Donor Renal Transplant Recipients1U01AI136779-01 · under PAR-16-270THOMSON, ANGUS WUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$1,000,075ZAI1
2018Repeat Ivermectin Mass Drug Administrations for MALaria control II (RIMDAMAL II): a double-blind cluster randomized trial for integrated control of malaria1U01AI138910-01 · under PAR-16-270FOY, BRIAN DAVIDPARIKH, SUNILCOLORADO STATE UNIVERSITY, CO$745,773ZAI1
2018A Phase II Controlled Trial of Allogeneic Mesenchymal Stem Cells for the Treatment of Refractory Lupus1U01AI125159-01A1 · under PAR-16-270GILKESON, GARY SMEDICAL UNIVERSITY OF SOUTH CAROLINA, SC$720,193ZAI1
2017HOPE in Action: A clinical trial of HIV-to-HIV deceased donor kidney transplantation1U01AI134591-01 · under PAR-16-270DURAND, CHRISTINE MARIESEGEV, DORRY L.JOHNS HOPKINS UNIVERSITY, MD$1,578,717ZAI1
2017Low-dose IL-2 in Established T1D1U01AI125057-01A1 · under PAR-16-270MALEK, THOMAS RPUGLIESE, ALBERTOSKYLER, JAY SUNIVERSITY OF MIAMI SCHOOL OF MEDICINE, FL$1,529,390ZAI1
2017High vs. Standard Dose Flu Vaccine in Adult Stem Cell Transplant Recipients1U01AI132004-01 · under PAR-16-270HALASA, NATASHA BASSAMVANDERBILT UNIVERSITY MEDICAL CENTER, TN$832,698ZAI1
20173BNC117 and 10-1074 to suppress HIV-1 replication and reduce the reservoir1U01AI129825-01 · under PAR-13-151CASKEY, MARINAROCKEFELLER UNIVERSITY, NY$819,850ZAI1
2017Controlled Infection Trial to Test Efficacy of Hookworm Vaccine with Different TLR Agonists1U01AI129789-01 · under PAR-13-151BETHONY, JEFFREY MICHAELDIEMERT, DAVID JOSEPHGEORGE WASHINGTON UNIVERSITY, DC$797,494ZAI1
2017MTBVAC Phase 1b/2a Randomized, Double-blind, Active-controlled, Safety, Immunogenicity, and Dose-escalation Study in Adults with and without Latent Tuberculosis Infection in South Africa1U01AI131861-01 · under PAR-16-270GINSBERG, ANN MHATHERILL, MARKAERAS, MD$210,000ZAI1
2016Comparison of High vs. Standard Dose Flu Vaccine in Pediatric Stem Cell Transplant Recipients1U01AI125135-01 · under PAR-13-151HALASA, NATASHA BASSAMVANDERBILT UNIVERSITY MEDICAL CENTER, TN$1,711,635ZAI1
2016Gene therapy for SCID-X1 with low dose busulfan and a SIN-lentiviral vector1U01AI125051-01 · under PAR-13-151PAI, SUNG-YUNBOSTON CHILDREN'S HOSPITAL, MA$1,132,346ZAI1
2016Cadaveric Donor Lung and Bone Marrow Transplantation in Immunodeficiency Diseases1U01AI125050-01 · under PAR-13-151MCDYER, JOHN FSZABOLCS, PAULUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$959,096ZAI1
2016Hallmarks of Protective Immunity in Sequential Rhinovirus Infections in Humans1U01AI125056-01 · under PAR-13-151TURNER, RONALD B.WOODFOLK, JUDITH AUNIVERSITY OF VIRGINIA, VA$898,658ZAI1
2015School Inner-City Asthma Intervention Study1U01AI110397-01A1 · under PAR-13-151PHIPATANAKUL, WANDABOSTON CHILDREN'S HOSPITAL, MA$1,743,949ZAI1
2015Impact of CCR5 Blockade in HIV+ Kidney Transplant Recipients1U01AI118594-01 · under PAR-13-151STOCK, PETER GUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$1,670,008ZAI1
2015Efficacy of Antibiotics in Children with Acute Sinusitis: Which Subgroups Benefit?1U01AI118506-01 · under PAR-13-151SHAIKH, NADERWALD, ELLENUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$1,021,834ZAI1
20153BNC117 mAb in HIV-infected subjects on combination ART1U01AI118536-01 · under PAR-13-151CASKEY, MARINAROCKEFELLER UNIVERSITY, NY$840,281ZAI1
2015Experimental human infection with isogenic mutants of Neisseria gonorrhoeae1U01AI114378-01A1 · under PAR-13-151HOBBS, MARCIA METZGARUNIV OF NORTH CAROLINA CHAPEL HILL, NC$701,174ZAI1
2015Phase 1 Trial of Na-APR-1 and Na-GST-1 Hookworm Vaccines in Brazilian Adults1U01AI116414-01 · under PAR-13-151DIEMERT, DAVID JOSEPHGEORGE WASHINGTON UNIVERSITY, DC$675,140ZAI1
2015Safety and efficacy of PfSPZ malaria vaccine in malaria-exposed adults1U01AI112367-01 · under PAR-13-151PLOWE, CHRISTOPHER V.UNIVERSITY OF MARYLAND BALTIMORE, MD$661,033ZAI1
2015Cell Phone Video Directly Observed Therapy to Monitor Short Course LTBI Treatment1U01AI116392-01 · under PAR-13-151GARFEIN, RICHARD SUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$648,715ZAI1
2015Phase IIa Clinical Trial of the Reprofiled Drug Auranofin for GI Protozoa1U01AI110435-01A1 · under PAR-13-151REED, SHARON LUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$629,075ZAI1
2014Towards Eradication: Reducing Proviral HIV DNA with Interferon-a Immunotherapy1U01AI110434-01 · under PAR-13-151MONTANER, LUIS JWISTAR INSTITUTE, PA$1,708,367ZAI1
2014Donor-Alloantigen-Reactive Regulatory T Cell Therapy in Liver Transplantation1U01AI110658-01 · under PAR-13-151BLUESTONE, JEFFREY AFENG, SANDYKANG, SANG-MOTANG, QIZHIUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$983,209ZAI1
2014Early Infant Treatment1U01AI114235-01 · under PAR-13-151KURITZKES, DANIEL R.LICHTERFELD, MATHIASSHAPIRO, ROGER LHARVARD SCHOOL OF PUBLIC HEALTH, MA$979,999ZHD1
2014Searching for Persistence in Lyme Disease1U01AI109656-01A1 · under PAR-13-151HU, LINDEN TTUFTS MEDICAL CENTER, MA$817,356ZAI1
2014Dipyridamole as a Modulator of HIV-1 Inflammation by Adenosine Regulation1U01AI110410-01 · under PAR-13-151MACATANGAY, BERNARD JONAS CRIDDLER, SHARONUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$640,365ZAI1
2014Randomized Controlled Trial of Treatment of Male Partners of Women with BV1U01AI108509-01A1 · under PAR-13-151SCHWEBKE, JANE R.UNIVERSITY OF ALABAMA AT BIRMINGHAM, AL$615,470ZAI1
2014Nikkomycin Z treatment of primary pneumonia due to Coccidioides1U01AI112406-01 · under PAR-13-151LARWOOD, DAVIDVALLEY FEVER SOLUTIONS, INC., AZ$211,459ZAI1

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