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NIH funding notice PAR-25-025

NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics for HLBS Disorders (R33 CT Required)

Open. Closes February 3, 2027.

Posted
December 5, 2024
Close date
February 3, 2027
Activity codes
R33
Institutes taking part
NHLBI

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

  1. Reissues: PAR-24-172 NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics for HLBS Disorders (R33 CT Required)
  2. 2 steps back: PAR-21-118 NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics (R33 Clinical Trial Required)
  3. 3 steps back: PAR-18-684 NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics (R33 Clinical Trial Required)

Who won it before

3 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $3,396,345 in first-year total cost, median $881,207.

Most frequent study sections

  1. Special Emphasis Panel[ZHL1 CSR-B (F4)]1
  2. Special Emphasis Panel[ZHL1 CSR-H (F1)]1
  3. Special Emphasis Panel[ZHL1 CSR-Z (O2)]1

Most frequent institutions

  1. AUGUSTA UNIVERSITY1
  2. CHILDREN'S RESEARCH INSTITUTE1
  3. PHOENICIA BIOSCIENCES, INC.1
Competing awards under PAR-25-025 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2023Phase I study of panobinostat in adults with sickle cell disease: novel approach to recruitment and retention1R33HL162681-01 · under PAR-21-118KUTLAR, ABDULLAHPACE, BETTY SUEAUGUSTA UNIVERSITY, GA$782,126ZHL1
2020Development of a Clinical Hemoglobin Modulator1R33HL147845-01A1 · under PAR-18-684FALLER, DOUGLAS VKUO, KEVINPERRINE, SUSAN PARKSINGER, SYLVIA TPHOENICIA BIOSCIENCES, INC., MA$1,733,012ZHL1
2019Mesenchymal Stromal Cell Delivery through Cardiopulmonary Bypass in Pediatric Cardiac Surgery1R33HL146394-01 · under PAR-18-684BOLLARD, CATHERINE M.ISHIBASHI, NOBUYUKIJONAS, RICHARD ACHILDREN'S RESEARCH INSTITUTE, DC$881,207ZHL1

Data: Grants.gov's daily extract and NIH's notice pages and award files, in ScienceGraph release conductgrants-2026-11-09-0.1.0. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.

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PAR-25-025: NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics for HLBS Disorders (R33 CT Required) | ScienceDex | ConductScience