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NIH funding notice PAR-25-291

Utilizing Invasive Recording and Stimulating Opportunities in Humans to Advance Neural Circuitry Understanding of Mental Health Disorders (R21 Clinical Trial Optional)

Open. Closes January 7, 2028.

Posted
November 22, 2024
Close date
January 7, 2028
Activity codes
R21
Institutes taking part
NIMH

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

  1. Reissues: PAR-23-101 Utilizing Invasive Recording and Stimulating Opportunities in Humans to Advance Neural Circuitry Understanding of Mental Health Disorders (R21 Clinical Trial Optional)
  2. 2 steps back: PAR-21-288 Utilizing Invasive Recording and Stimulating Opportunities in Humans to Advance Neural Circuitry Understanding of Mental Health Disorders (R21 Clinical Trial Optional)
  3. 3 steps back: RFA-MH-20-351 Utilizing Invasive Recording and Stimulating Opportunities in Humans to Advance Neural Circuitry Understanding of Mental Health Disorders (R21 Clinical Trial Optional)

Who won it before

9 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $2,290,645 in first-year total cost, median $236,250.

Most frequent study sections

  1. Special Emphasis Panel[ZMH1 ERB-Q (03)]4
  2. Neural Basis of Psychopathology, Addictions and Sleep Disorders Study Section[NPAS]2
  3. Adult Psychopathology and Disorders of Aging Study Section[APDA]1
  4. Human Complex Mental Function Study Section[HCMF]1
  5. Special Emphasis Panel[ZMH1 ERB-Q (06)]1

Most frequent institutions

  1. UNIVERSITY OF CALIFORNIA, SAN FRANCISCO2
  2. DARTMOUTH-HITCHCOCK CLINIC1
  3. ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI1
  4. OHIO STATE UNIVERSITY1
  5. STANFORD UNIVERSITY1
Competing awards under PAR-25-291 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2025Neural Basis of Human Working Memory1R21MH139624-01 · under PAR-23-101BICK, SARAH KATHLEENCONSTANTINIDIS, CHRISTOSENGLOT, DARIO JWILLIAMS ROBERSON, SHAWNIQUAVANDERBILT UNIVERSITY, TN$470,996HCMF
2024Behavioral and Neuronal Correlates of Human Mood States1R21MH134172-01A1 · under PAR-23-101KELLER, COREY JPARVIZI, JOSEFSTANFORD UNIVERSITY, CA$193,000NPAS
2023Stimulation-induced modulation of fronto-limbic responses to threat1R21MH133055-01 · under PAR-21-288GOODMAN, ADAM MUNIVERSITY OF ALABAMA AT BIRMINGHAM, AL$222,750APDA
2022Electrophysiological Read-Out of Interoceptive Processing in the Insula1R21MH126968-01A1 · under RFA-MH-20-351WATERS, ALLISON CANDICEICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY$247,980ZMH1
2022Targeting DBS Therapy to the OCD Network Using fMRI and Intracranial Recordings1R21MH130914-01 · under PAR-21-288LEE, ANDREW MOSESMORRISON, MELANIE AUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$242,250NPAS
2022Using intracranial recording, stimulation, and computational modeling to map role of the subthalamic nucleus in human decision making1R21MH127007-01A1 · under RFA-MH-20-351RATCLIFF, ROGERSHAIKHOUNI, AMMAROHIO STATE UNIVERSITY, OH$236,250ZMH1
2022A neural population model-based characterization and modulation of neural oscillations underlying cognitive control in healthy and depressed/anxious human subjects1R21MH127009-01A1 · under RFA-MH-20-351BASU, ISHITAUNIVERSITY OF CINCINNATI, OH$202,500ZMH1
2021Deciphering principles of network dynamics underlying depression symptom severity from multi-day intracranial recordings in patients with major depression1R21MH124759-01 · under RFA-MH-20-351KRYSTAL, ANDREW DUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$242,250ZMH1
2021Neuromodulation of affective valence in humans by amygdala stimulation1R21MH124674-01A1 · under RFA-MH-20-351BUJARSKI, KRZYSZTOFDARTMOUTH-HITCHCOCK CLINIC, NH$232,669ZMH1

Data: Grants.gov's daily extract and NIH's notice pages and award files, in ScienceGraph release conductgrants-2026-11-09-0.1.0. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.

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