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NIH funding notice PAR-25-298

Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Not Allowed)

Open. Closes January 7, 2028.

Posted
December 6, 2024
Close date
January 7, 2028
Activity codes
R15
Institutes taking part
NIDCR, NEI, NHLBI, NHGRI, NIA, NIAAA, NIAID, NIAMS, NIBIB, NICHD, NIDCD, NIDA, NIEHS, NIMH, NINDS, NINR, NCCIH, ORIP, NCI

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

  1. Reissues: PAR-22-060 Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Not Allowed)
  2. 2 steps back: PAR-19-134 Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Not Allowed)

Who won it before

185 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $79,635,067 in first-year total cost, median $439,428.

Most frequent study sections

  1. Special Emphasis Panel[ZRG1 MDCN-R (86)]18
  2. Special Emphasis Panel[ZRG1 OTC-A (80)]12
  3. Special Emphasis Panel[ZRG1 CDPT-J (80)]11
  4. Special Emphasis Panel[ZRG1 IDM-S (83)]8
  5. Language and Communication Study Section[LCOM]4

Most frequent institutions

  1. NEW YORK INST OF TECHNOLOGY9
  2. EAST TENNESSEE STATE UNIVERSITY8
  3. WESTERN UNIVERSITY OF HEALTH SCIENCES8
  4. MARSHALL UNIVERSITY7
  5. MERCER UNIVERSITY MACON7
Competing awards under PAR-25-298 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2025The role of orosomucoid1 in skeletal muscle aging during an optimized autophagy activity intervention1R15AG095821-01 · under PAR-22-060DOS SANTOS SILVA, KLEITON AROWAN UNIVERSITY, NJ$530,469ZRG1
2025Dissecting the Role of Lrh1 in Phthalate-Related Reproductive Impairments: A Cellular and Molecular Approach1R15ES037124-01A1 · under PAR-22-060JAUREGUI, ESTELA JASMINMIDWESTERN UNIVERSITY (GLENDALE AZ), AZ$521,992NMHD
2025RgIA5474 as a Novel α9α10 Nicotinic Acetylcholine Receptor Antagonist to Treat Migraine1R15NS143081-01 · under PAR-22-060XIE, YANHUANEW YORK INST OF TECHNOLOGY, NY$472,592NPI
2025MicroRNA 34/449 family plays a critical role in choroid plexus differentiation and tumorigenesis1R15CA287297-01A1 · under PAR-22-060ZHAO, HAOTIANNEW YORK INST OF TECHNOLOGY, NY$459,000ZRG1
2025Anatomy and Physiology of Molecular Layer Heterotopia1R15NS137226-01A1 · under PAR-22-060RAMOS, RADDY LEONARDONEW YORK INST OF TECHNOLOGY, NY$459,000DBD
2025Deciphering novel UPS regulation of Sgf73/ataxin-7 in controlling SAGA and associated functions in gene expression1R15CA290595-01A1 · under PAR-22-060BHAUMIK, SUKESH R.SOUTHERN ILLINOIS UNIVERSITY CARBONDALE, IL$445,500ZRG1
2025Engineering Natural Killer Cell Derived Extracellular Vesicular Nanodrug for Tumor Targeted Bioimaging and Therapy1R15EB036962-01 · under PAR-22-060ARYAL, SANTOSHUNIVERSITY OF TEXAS TYLER, TX$441,000INN
2025Mitochondrial Aging Promotes Inflammation2R15AG068957-02A1 · under PAR-22-060PANNEERSEELAN-BHARATH, LEENAMERRIMACK COLLEGE, MA$433,949AI
2025Engineering Natural Killer Cells to Target Acute Myeloid Leukemia with HLA-DR Loss1R15CA293657-01A1 · under PAR-22-060XIE, JIANMINGWESTERN UNIVERSITY OF HEALTH SCIENCES, CA$429,000ZRG1
2025Investigating the roles of UBE3A and TRPML1 in extracellular vesicle regulation to understand Angelman syndrome pathogenesis2R15MH101703-04A1 · under PAR-22-060BI, XIAONINGWESTERN UNIVERSITY OF HEALTH SCIENCES, CA$429,000DBD
2025Examining Additional Attributes of Muscle Function for Cognitive Impairment in Older Adults2R15AG072348-02 · under PAR-22-060MCGRATH, RYANNORTH DAKOTA STATE UNIVERSITY, ND$421,230AIMR
2025Mechanistic studies on the role of GABA type A ion channel (GABAA) receptors in triple negative breast cancer1R15CA301412-01 · under PAR-22-060MERCIER, ISABELLESAINT JOSEPH'S UNIVERSITY, PA$420,600ZRG1
2025Peptide-Doxorubicin Conjugates for Mitigating Cardiotoxicity and Overcoming Drug Resistance in Cancer1R15CA301437-01 · under PAR-22-060PARANG, KEYKAVOUSYANG, SUNCHAPMAN UNIVERSITY, CA$415,500ZRG1
2025Behavioral and Neural Correlates of Adaptive Risk-Taking Behavior in Preschool-Aged Children1R15MH137634-01A1 · under PAR-22-060CREMONE-CAIRA, AMANDA MARIEMERRIMACK COLLEGE, MA$413,811HCMF
2025Comparison of Tirzepatide, Retatrutide, and Crocetin, for Mitigation of Alzheimer's-like Pathology in a Mouse Model of Alzheimer’s Disease1R15AG091199-01 · under PAR-22-060ROBISON, LISA SUZANNESPETH, ROBERT CHARLESNOVA SOUTHEASTERN UNIVERSITY, FL$372,400CDIN
2024Novel Mcl-1 Inhibitor for Combination Treatment of Refractory Multiple Myeloma1R15CA290481-01A1 · under PAR-22-060PANDEY, MANOJ KUMARROWAN UNIVERSITY, NJ$499,902ZRG1
2024Investigating the potential impact of a low-fat high fiber diet in limiting TBI-induced neurodegenerative and inflammatory changes.1R15NS137260-01 · under PAR-22-060ACHARYA, NIMISH KUMARROWAN UNIVERSITY SCHOOL/OSTEOPATHIC MED, NJ$498,713BINP
2024Solid Phase Microextraction as a New Tool for Quantifying Antibody Drugs in Breast Cancer and Building PK-PD models1R15CA287244-01 · under PAR-22-060MUSTEATA, FLORIN MARCELALBANY COLLEGE OF PHARMACY, NY$480,000ZRG1
2024G0S2 and lipid metabolism in the regulation of hematopoietic development1R15HL172157-01 · under PAR-22-060EIRING, ANNA MARIETEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER AT EL PASO, TX$480,000HTBT
2024Development and Initial Validation of a Palliative Care Readiness Tool for Older Adults with Cancer.1R15AG081886-01A1 · under PAR-22-060PARAJULI, JYOTSANAUNIVERSITY OF NORTH CAROLINA CHARLOTTE, NC$475,748HSQE
2024Benefits of, challenges with, and suggestions for improving pediatric telehealth: The perspectives of adolescents1R15HD114022-01 · under PAR-22-060KODJEBACHEVA, GERGANA DAMIANOVAUNIVERSITY OF MICHIGAN AT FLINT, MI$468,000CMGC
2024Development of a Novel Vasorelaxing Peptide1R15HL173818-01 · under PAR-22-060TRAN, KIMDES MOINES UNIV OSTEOPATHIC MEDICAL CTR, IA$453,404IVPP
2024Is ERBB4 a Driver of BRAF WT Melanomas?1R15CA280767-01A1 · under PAR-22-060RIESE, DAVID J.AUBURN UNIVERSITY AT AUBURN, AL$450,826ZRG1
2024Disturbed sleep and atherosclerosis1R15HL175612-01 · under PAR-22-060GALKINA, ELENA VOLD DOMINION UNIVERSITY, VA$450,000AVI
2024Characterization of HER2 inhibitors with a novel mechanism of action1R15CA283780-01A1 · under PAR-22-060ABDELAZIZ, MAY H.UNIVERSITY OF TEXAS TYLER, TX$447,195ZRG1
2024Role of Th2 cytokines in progenitor-mediated formation of tumor lymphatics1R15CA283669-01A1 · under PAR-22-060RAN, SOPHIASOUTHERN ILLINOIS UNIVERSITY SCH OF MED, IL$445,500ZRG1
2024Aryl hydrocarbon receptor regulation of energy metabolism2R15ES030556-02 · under PAR-22-060TISCHKAU, SHELLEY ASOUTHERN ILLINOIS UNIVERSITY SCH OF MED, IL$445,500BMDM
2024Regenerative and Rehabilitation Strategies to Reduce Inflammation Following Volumetric Muscle Loss Injury1R15AR083119-01A1 · under PAR-22-060WASHINGTON, TYRONE AUNIVERSITY OF ARKANSAS AT FAYETTEVILLE, AR$434,793ZRG1
2024Channelopathy of KCa2.3 and Zimmermann-Laband syndrome1R15NS130420-01A1 · under PAR-22-060ZHANG, MIAOCHAPMAN UNIVERSITY, CA$434,024BBM
2024Investigation of Human Gut-Derived Mesenchymal Stem Cells for Cellular Therapy1R15AI176177-01A1 · under PAR-22-060CHINNADURAI, RAGHAVANMERCER UNIVERSITY MACON, GA$429,545DHMI
2024Glutathione depletion in the CNS and its effects on Mtb infection2R15HL143545-02 · under PAR-22-060VENKETARAMAN, VISHWANATHWESTERN UNIVERSITY OF HEALTH SCIENCES, CA$429,000CNBT
2024The anatomical and functional study of the thymus - defining the milestones of the thymic aging in the elderly human population1R15AG078992-01A1 · under PAR-22-060SIMM, MALGORZATAUNIVERSITY OF PIKEVILLE, KY$428,397ASG
2024Rescuing myelination in viral infections of the juvenile brain1R15NS141047-01 · under PAR-22-060O'DONNELL, LAUREN ALENEDUQUESNE UNIVERSITY, PA$426,057CNBT
2024Manipulating Aberrant Calcium Signaling to Target Relapsed High-Risk Neuroblastoma1R15CA277188-01A1 · under PAR-22-060KOOMOA, DANA-LYNN TAKEKOWESTERN NEW ENGLAND UNIVERSITY, MA$423,743ZRG1
2024Effects of chronic intermittent hypoxia on cholinergic modulation at hypoglossal motoneurons1R15HL175526-01 · under PAR-22-060REVILL, ANN LOUISEMIDWESTERN UNIVERSITY (GLENDALE AZ), AZ$421,800ZRG1
2024Investigating the Roles of Pregnane X Receptor in Human Breast Cancers1R15CA287338-01 · under PAR-22-060CREAMER, BRADLEY ALLENSTAUDINGER, JEFFREY LKANSAS CITY UNIVERSITY, MO$420,000DBDT
2024Metabolic changes that promote adaptation of Listeria monocytogenes to oxidative stress and preserving intracellular redox homeostasis1R15AI180880-01 · under PAR-22-060ABDELHAMED, HOSSAM AMISSISSIPPI STATE UNIVERSITY, MS$418,270BV
2024Harnessing the potential of pharmacological small molecules to amplify VSV-based oncolytic viral therapy1R15CA290568-01 · under PAR-22-060CHAMCHEU, JEAN CHRISTOPHERSOUTHERN UNIV A&M COL BATON ROUGE, LA$408,966ZRG1
2024Asthma Self-Management Behaviors and Cognitive Autonomy: Developing an Adolescent Questionnaire1R15HL165313-01A1 · under PAR-22-060ISIK, ELIFTEXAS WOMAN'S UNIVERSITY, TX$393,180BMHO
2024Specifying Neurophysiology and Predicting Real-world Impact in Stuttering1R15DC021264-01A1 · under PAR-22-060TICHENOR, SETHDUQUESNE UNIVERSITY, PA$390,959MFSR
2024Glial Cells and Polyamine Signaling in the Central Nervous System2R15NS116478-02 · under PAR-22-060SKATCHKOV, SERGUEI NUNIVERSIDAD CENTRAL DEL CARIBE, PR$389,424CMBG
2024Developing and testing a measure of sociocultural norms related to interpregnancy intervals in African immigrants in the US.1R15HD116088-01 · under PAR-22-060OLORUNSAIYE, COMFORT Z.ARCADIA UNIVERSITY, PA$385,936CIHB
2024Pyk2 regulates extracellular vesicles release in GBM cells and modulates activation of tumor infiltrating myeloid cells1R15CA287203-01 · under PAR-22-060KUCHERYAVYKH, LILIAUNIVERSIDAD CENTRAL DEL CARIBE, PR$381,843ZRG1
2024A multi-method, multi-domain approach to evaluating preterm's effect on child growth and development1R15HD114083-01 · under PAR-22-060SAKYI, KWAME SARFOOAKLAND UNIVERSITY, MI$373,358RPPH
2023Characterizing and Targeting the Epigenetic Mechanisms Maintaining Neuroblastoma Tumor Initiating Cells1R15CA277659-01 · under PAR-22-060AGARWAL, SAURABHST. JOHN'S UNIVERSITY, NY$492,000ZRG1
2023Synergistic combination of Proteolysis Targeting Chimera with a translational formulation for the treatment of intractable lung carcinoma1R15CA271133-01A1 · under PAR-22-060PATEL, KETANKUMAR D.ST. JOHN'S UNIVERSITY, NY$492,000ZRG1
2023Serotonergic control of the sympathoadrenal stress response1R15NS132585-01 · under PAR-22-060CURRIE, KEVIN PROWAN UNIVERSITY, NJ$483,000ZRG1
2023New Nasal Spray Influenza Vaccine for Children1R15HD109732-01A1 · under PAR-22-060ZENG, MINGTAOTEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER AT EL PASO, TX$480,000ZRG1
2023Targeting secreted factors in endocrine resistant breast cancer therapy1R15CA271221-01A1 · under PAR-22-060JIN, KIDEOKALBANY COLLEGE OF PHARMACY, NY$480,000ZRG1
2023Transactional Success in the Texting Exchanges of People with Aphasia1R15DC020836-01A1 · under PAR-22-060AZIOS, JAMIE HHARBICK, SHIREE CONLINJAMES MADISON UNIVERSITY, VA$477,241LCOM
2023Emerin regulation of myogenic differentiation: implications for muscle disease2R15AR069935-04A1 · under PAR-22-060HOLASKA, JAMES MICHAELROWAN UNIVERSITY, NJ$475,680ZRG1
2023Targeting anti-viral and anti-inflammatory responses during ocular HSV-1 infection to prevent vision impairment.1R15EY035057-01 · under PAR-22-060RAMAPURAM, JAYACHANDRA BAUBURN UNIVERSITY AT AUBURN, AL$453,296ZRG1
2023Transformative Iron Metal Nanoparticles with Controlled Oxidation for Magnetic Particle Imaging.1R15EB034962-01 · under PAR-22-060JOHNSON, JACQUELINE AUNIVERSITY OF TENNESSEE SPACE INSTITUTE, TN$451,089ZRG1
2023A novel nanobody-based agonist-redirected checkpoint (ARC) molecule, aPD1-Fc-OX40L, for cancer immunotherapy1R15CA277677-01 · under PAR-22-060SANDEY, MANINDERAUBURN UNIVERSITY AT AUBURN, AL$449,910ZRG1
2023Shared Language Erosion Among Chinese Immigrant Families1R15HD112867-01 · under PAR-22-060LIN, HUAOKLAHOMA STATE UNIVERSITY STILLWATER, OK$448,800PDRP
2023The Impact of Early Life Stress On Amygdala Circuitry And Chronic Excessive Aggression1R15HD110925-01A1 · under PAR-22-060NORDMAN, JACOBSOUTHERN ILLINOIS UNIVERSITY CARBONDALE, IL$445,500BRLE
2023Characterization of the Regulation and Gene Targets of TBX2 in Rhabdomyosarcoma1R15CA274384-01A1 · under PAR-22-060DAVIE, JUDITH KIMBERLYSOUTHERN ILLINOIS UNIVERSITY CARBONDALE, IL$445,500ZRG1
2023Targeting oncogenic pathways for chemoprevention of head and neck cancer by FLLL121R15DE032063-01A1 · under PAR-19-134AMIN, A.R.M. RUHULMARSHALL UNIVERSITY, WV$444,000ZRG1
2023Zinc Protection Against Ischemia-Reperfusion Injury in Heart1R15HL168628-01 · under PAR-22-060PAN, ZUIUNIVERSITY OF TEXAS ARLINGTON, TX$443,022ZRG1
2023Immune regulation to Coccidioides infection1R15AI174173-01A1 · under PAR-22-060HOYER, KATRINA KUNIVERSITY OF CALIFORNIA, MERCED, CA$442,470IHD
2023Exploration of different immunotherapy modalities in osteosarcoma1R15CA283777-01 · under PAR-22-060AGARWAL, PAYALAUBURN UNIVERSITY AT AUBURN, AL$440,640ZRG1
2023Prospection in suicidal teens: Identifying a novel and malleable cognitive risk factor2R15MH113076-02A1 · under PAR-22-060GABA, AYORKORCOLUMBIA UNIVERSITY TEACHERS COLLEGE, NY$440,445CPDD
2023Role of pregnane x receptor activation on macrophage function and diabetic wound healing1R15ES035527-01 · under PAR-22-060HOWELL, GEORGE EMISSISSIPPI STATE UNIVERSITY, MS$439,500ZRG1
2023Effect of ambient heat on chronic kidney disease and end-stage kidney disease among US veterans1R15ES035227-01 · under PAR-22-060TITU, ABU MOHAMMED NASERUNIVERSITY OF MEMPHIS, TN$433,349KEDD
2023Pacemakers of Cholinergic Wave Activity in the Developing Retina1R15EY034305-01A1 · under PAR-22-060ZHANG, DAO-QIOAKLAND UNIVERSITY, MI$429,016DEV2
2023Astrocytic Heparan Sulfate 6-O-Sulfation in Brain Function1R15NS130456-01 · under PAR-22-060ZHAO, JERRY YINGTAONEW YORK INST OF TECHNOLOGY, NY$428,400ZRG1
2023Deciphering the Role of AMPK in Doxorubicin Cardiotoxicity1R15HL163707-01A1 · under PAR-22-060LIANG, QIANGRONGNEW YORK INST OF TECHNOLOGY, NY$428,400ZRG1
2023Obesity-related hypertension: the contribution of PPAR gamma acetylation and asprosin1R15HL165328-01A1 · under PAR-22-060CARRILLO-SEPULVEDA, MARIA ALICIANEW YORK INST OF TECHNOLOGY, NY$428,400IVPP
2023Multi-Stakeholder Determinants of Medicare Diabetes Prevention Program Implementation and Participation1R15HL163736-01A1 · under PAR-22-060WARZISKI TURK, MELANIE TDUQUESNE UNIVERSITY, PA$426,032SIHH
2023Blending Dentin to Dentin: Biometric Hydrogels for Dentin Tissue Engineering1R15DE032836-01A1 · under PAR-22-060ROCHA DE OLIVEIRA CARRILHO, MARCELAMIDWESTERN UNIVERSITY, IL$421,800ZRG1
2023Endothelial Smad3 as a Novel Target to Avert Chemotherapy Induced Cardiomyopathy1R15HL170243-01 · under PAR-22-060KONOREV, EUGENE AKANSAS CITY UNIVERSITY, MO$408,599BBHV
2023Title: In Vitro Analysis of the Effects of Acute and Chronic Phthalate Exposures on Leydig Cell Testosterone Production, and the Molecular Mechanisms Involved2R15ES032102-03 · under PAR-22-060TRAORE, KASSIMDUQUESNE UNIVERSITY, PA$401,895ICER
2023AI-based Fall-Risk Assessment during Daily Activities in Post Stroke Survivors using Smartphones1R15HD110941-01 · under PAR-22-060SOANGRA, RAHULCHAPMAN UNIVERSITY, CA$391,253CIDH
2023Human mast cells as a platform for new cancer immunotherapy strategies1R15CA283490-01 · under PAR-22-060KEPLEY, CHRIS LLIBERTY UNIVERSITY, INC., VA$372,846ZRG1
2023Cannabinoid Signaling Interactions During Axon Development in situ1R15DA058203-01 · under PAR-22-060ELUL, TAMIRATOURO UNIVERSITY OF CALIFORNIA, CA$364,250ZRG1
2022Functional Biomarkers for Prediction of Hospitalization, Long-Term Care Placement, and Mortality in Older Adults with Cardiometabolic Multimorbidity1R15AG070730-01A1 · under PAR-19-134GORE, SHWETAKUMAR, AMITMGH INSTITUTE OF HEALTH PROFESSIONS, MA$501,342NAME
2022Characterizing Regulatory Mechanisms Underlying Drug Resistance in Breast Cancer Using Keratin 191R15CA267890-01 · under PAR-19-134CHOY, JOHN SINGCATHOLIC UNIVERSITY OF AMERICA, DC$473,458ZRG1
2022Does growth efficiency determine the inoculum effect?1R15AI159902-01A1 · under PAR-19-134SMITH, ROBERT PNOVA SOUTHEASTERN UNIVERSITY, FL$462,459ZRG1
2022Spinal Manipulative Therapy vs. Prescription Drug Therapy for Care of Aged Medicare Beneficiaries with Neck Pain2R15AT010035-02 · under PAR-19-134WHEDON, JAMES M.SOUTHERN CALIFORNIA UNIV OF HEALTH SCIS, CA$459,595ZAT1
2022Epitranscriptomic control of ROS1R15CA274603-01 · under PAR-19-134CARPENTER, MICHAELSUNY POLYTECHNIC INSTITUTE, NY$459,347ZRG1
2022The Patient Journey for Children with Medical Complexity during Pandemic Era andits implications.1R15HD109791-01 · under PAR-19-134ASAN, ONURTHE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGY, NJ$456,750HSQE
2022Trends of disparities in breast cancer progression and health care considering multilevel risk factors2R15MD012387-02 · under PAR-19-134YU, QINGZHAOLSU HEALTH SCIENCES CENTER, LA$453,673CHSB
2022Obesity promoting protein malonylation and chondrocyte metabolic dysfunction in osteoarthritis development1R15AR080813-01 · under PAR-19-134ZHU, SHOUANOHIO UNIVERSITY ATHENS, OH$453,000ZRG1
2022Molecular Basis of the Selective Assembly of Functionally Distinct PRC1s1R15CA267804-01A1 · under PAR-19-134KIM, CHONGWOO AMIDWESTERN UNIVERSITY (GLENDALE AZ), AZ$450,000MSFB
2022The role of SWI/SNF chromatin remodelers in homologous recombination and genome stability1R15CA267864-01A1 · under PAR-19-134VELEZ-CRUZ, RENIERMIDWESTERN UNIVERSITY, IL$449,330ZRG1
2022Myelination and Resilience Against Limbic Alpha-Synucleinopathy1R15NS130532-01 · under PAR-22-060LEAK, REHANA KHANDUQUESNE UNIVERSITY, PA$447,461ZRG1
2022Thymidine Phosphorylase: a Novel Target of Antiplatelet Therapy2R15HL145573-02 · under PAR-19-134LI, WEIMARSHALL UNIVERSITY, WV$444,000HTBT
2022The Role of Oxidative Signaling through Na/K-ATPase in PNx-induced Anemia1R15HL164682-01 · under PAR-19-134LIU, JIANGMARSHALL UNIVERSITY, WV$444,000PBKD
2022Role of Alternate Sensorimotor Pathway Degeneration in Motor Function in Acute Stroke1R15NS121970-01A1 · under PAR-19-134POTTER-BAKER, KELSEYUNIVERSITY OF TEXAS RIO GRANDE VALLEY, TX$443,963ZRG1
2022Sleep disturbance and inflammation as determinants of social cognition and behavior: An intensive longitudinal study of adults with schizophrenia-spectrum disorders1R15MH129814-01 · under PAR-19-134JORDAN, SARA SYTSMAUNIVERSITY OF SOUTHERN MISSISSIPPI, MS$443,811MESH
2022Molecular Mechanisms Underlying Somatotrope Differentiation and Function1R15HD107430-01 · under PAR-19-134ELLSWORTH, BUFFY SUESOUTHERN ILLINOIS UNIVERSITY CARBONDALE, IL$442,500CSME
2022Enhancing Tumor Antigen Presentation with Complement Targeted Nanoparticles2R15CA227740-02 · under PAR-19-134KULLBERG, MAX PETERMARTINSON, HOLLY AUNIVERSITY OF ALASKA ANCHORAGE, AK$441,796ZRG1
2022The role of neuro-immune synapse in macrophage migration1R15HL157836-01A1 · under PAR-19-134YAKUBENKO, VALENTIN PEAST TENNESSEE STATE UNIVERSITY, TN$439,475ZRG1
2022Novel ocular hypotensive and neuroprotective microparticle-based hydrogen sulfide delivery system1R15EY032275-01A1 · under PAR-19-134OPERE, CATHERINE ASINGH, SOMNATHCREIGHTON UNIVERSITY, NE$436,500ZRG1
2022Age-related neuronal regulation of thermogenesis and lipid metabolism1R15AG078768-01 · under PAR-19-134LO, CHUNMIN C.OHIO UNIVERSITY ATHENS, OH$435,290BMDM
2022CAPER, a New Regulator of DNA Damage and Repair in Triple Negative Breast Cancer1R15CA242344-01A1 · under PAR-19-134JASMIN, JEAN-FRANCOISMERCIER, ISABELLESAINT JOSEPH'S UNIVERSITY, PA$434,998ZRG1
2022Safety and Effectiveness of Opioid Tapering among Older Adults2R15DA046036-02 · under PAR-19-134YANG, YIUNIVERSITY OF MISSISSIPPI, MS$432,303BGES
2022Pain-induced impulsivity in rats and its mechanisms1R15DA055202-01 · under PAR-19-134NAZARIAN, ARBIWESTERN UNIVERSITY OF HEALTH SCIENCES, CA$429,000ZRG1
2022Deciphering the role of lysosomal membrane permeabilization in Diabetic Cardiac Injury1R15HL161737-01 · under PAR-19-134KOBAYASHI, SATORUNEW YORK INST OF TECHNOLOGY, NY$428,400ZRG1
2022Mechanism of telomere attrition and premature T cell aging during HIV infection.1R15AG076370-01 · under PAR-19-134ZHAO, JUANEAST TENNESSEE STATE UNIVERSITY, TN$427,966HCCS
2022Development of a theory-based framework and measures of acculturation for African immigrants.1R15MD017012-01A1 · under PAR-19-134KANINJING, ERNESTGEORGIA COLLEGE AND STATE UNIVERSITY, GA$426,025HHD
2022The role of ROS on beta-2-adrenergic receptor function in human airway2R15HL138603-02 · under PAR-19-134MONIRI, NADER HMERCER UNIVERSITY MACON, GA$424,500ZRG1
2022Crosstalk between CES1 and PPAR gamma and LXR alpha in macrophages1R15HL157818-01A1 · under PAR-19-134ROSS, MATTHEW KMISSISSIPPI STATE UNIVERSITY, MS$420,691ZRG1
2022Investigation of AhR Ligands on FcGamma Receptor Signaling: Consequences of Antibody Suppression2R15ES027650-02 · under PAR-19-134KAPLAN, BARBARA LEE-FAUBERTMISSISSIPPI STATE UNIVERSITY, MS$419,864ZRG1
2022Pharmaceutical Nanofactories: Intracellular synthesis of bioactive drug molecules1R15CA271365-01 · under PAR-19-134TREWYN, BRIANCOLORADO SCHOOL OF MINES, CO$418,826ZRG1
2022Examining the feasibility of a wearable device for fetal heart rate monitoring through interdisciplinary research1R15HD107526-01 · under PAR-19-134KEENE WOODS, NIKKIWICHITA STATE UNIVERSITY, KS$413,347CIDH
2022A Health Education Program to Increase Hope and Improve Energy Balance Among Seniors in the Urban Subarctic1R15AG072369-01A1 · under PAR-19-134HOWELL, BRITTENY MUNIVERSITY OF ALASKA ANCHORAGE, AK$382,750SPIP
2022Determining the causal pathways of social and environmental predictors of high-risk alcohol drinking among college students1R15AA029256-01A1 · under PAR-19-134COUTURE, MARIE-CLAUDEGRINSHTEYN, ERINUNIVERSITY OF SAN FRANCISCO, CA$359,419SSPA
2022Behavioral and Neural Measures of Spoken Word Recognition in Late Language Emergence1R15DC020290-01 · under PAR-19-134SIMMONS, ELIZABETHSACRED HEART UNIVERSITY, CT$355,842LCOM
2022Cell-Meditated Inflammatory Pathway and Diabetic Retinopathy1R15EY033551-01 · under PAR-19-134TSIN, ANDREW T CUNIVERSITY OF TEXAS RIO GRANDE VALLEY, TX$355,110ZRG1
2022Goodnight mouse: sleep and sepsis1R15HL159554-01A1 · under PAR-19-134WALKER, WENDY ELIZABETHTEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER AT EL PASO, TX$134,696SAT
2021The impact of dysarthria on communicative participation in people with ALS1R15DC018944-01A1 · under PAR-19-134CONNAGHAN, KATHRYN PATRICIAMGH INSTITUTE OF HEALTH PROFESSIONS, MA$498,575LCOM
2021A novel Quadruple Knockout Mtb vaccine against tuberculosis1R15AI156647-01 · under PAR-19-134DHANDAYUTHAPANI, SUBRAMANIANTEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER AT EL PASO, TX$492,258ZRG1
2021Hydroxymethylation, Incident Type 2 Diabetes and Incident Obesity1R15HL152330-01A1 · under PAR-19-134DAI, JUNDES MOINES UNIV OSTEOPATHIC MEDICAL CTR, IA$488,819KNOD
2021Summer slide, glide, or gain: The effects of socioeconomic status and reading disability on summer reading outcomes1R15HD102881-01A1 · under PAR-19-134CHRISTODOULOU, JOANNAMGH INSTITUTE OF HEALTH PROFESSIONS, MA$478,848LCOM
2021To Study Mechanisms of a Non-Pharmacological Treatment Strategy for Alzheimer’s disease1R15AT010789-01A1 · under PAR-19-134COSTA, BLAISEVIRGINIA COLLEGE OF OSTEOPATHIC MEDICINE, VA$474,750ZAT1
2021Defining the cellular and molecular mechanisms of how toxicants disrupt mitochondrial DNA homeostasis1R15ES033394-01 · under PAR-19-134YOUNG, MATTHEW JSOUTHERN ILLINOIS UNIVERSITY CARBONDALE, IL$463,378SIEE
2021MECHANISM OF IOP-LOWERING EFFECTS OF HYDROGEN SULFIDE1R15EY032274-01 · under PAR-19-134MBYE, YA FATOU NJIETEXAS SOUTHERN UNIVERSITY, TX$458,859ZRG1
2021INCREASING CLINICAL ACCESS BY REDUCING SCAN TIME OF DYNAMIC NUCLEAR CARDIAC IMAGING WITH SUPERIOR DIAGNOSIS1R15EB030807-01A1 · under PAR-19-134MITRA, DEBASISFLORIDA INSTITUTE OF TECHNOLOGY, FL$455,104ITD
2021Mechanisms of Age-Related Impairments in Human Skeletal Muscle Glucose Metabolism1R15AG073922-01 · under PAR-19-134CONSITT, LESLIEOHIO UNIVERSITY ATHENS, OH$453,000CSME
2021Exploring Outstanding Performance in Low Readmission from Skilled Nursing Facilities for Older Adults (EXPLORE-SNF)1R15AG067456-01A1 · under PAR-19-134MINGES, KARL EMERYUNIVERSITY OF NEW HAVEN, CT$447,960HSOD
2021Neural and Vascular Mechanisms of Elevated Cardiovascular Disease Risk in African American Women1R15HL156128-01 · under PAR-19-134BROTHERS, ROBERT MATTHEWUNIVERSITY OF TEXAS ARLINGTON, TX$447,615HM
2021Targeting the Oncogenic Transcription Factor IRF4 in Hematological Malignancies1R15DE029621-01A1 · under PAR-19-134NING, SHUNBINEAST TENNESSEE STATE UNIVERSITY, TN$447,000ZRG1
2021Using Zebrafish to Model Developmental and Multigenerational Volatile Organic Compound Toxicity1R15ES033361-01 · under PAR-19-134HORZMANN, KATHARINE ANN MARIEAUBURN UNIVERSITY AT AUBURN, AL$446,820SIEE
2021Capsaicin and small cell lung cancer therapy2R15CA161491-03 · under PAR-19-134DASGUPTA, PIYALIMARSHALL UNIVERSITY, WV$444,000ZRG1
2021Investigating Sex Differences in Astrocyte-Mediated Synaptic Development1R15MH126345-01 · under PAR-19-134RISHER, WILLIAM CHRISTOPHERMARSHALL UNIVERSITY, WV$444,000ZRG1
2021Elucidating the role of the Branched Chain Aminotransferases (BCATc and BCATm) as novel metabolic checkpoints of anti-lymphoma T cell immunity1R15CA249796-01A1 · under PAR-19-134ANANIEVA-STOYANOVA, ELITSA ANTONOVADES MOINES UNIV OSTEOPATHIC MEDICAL CTR, IA$443,548ZRG1
2021Mapping activeness of very small tumors in breast for patient stratification1R15EB030809-01 · under PAR-19-134YUAN, BAOHONGUNIVERSITY OF TEXAS ARLINGTON, TX$442,546ZRG1
2021Unravelling the mechanism of acai BDS-anticancer drug interaction: A preliminary approach1R15AT011047-01A1 · under PAR-19-134CALDERON, ANGELA ISABELAUBURN UNIVERSITY AT AUBURN, AL$440,590ZAT1
2021The Ubiquitin Sensor p62 Is A Novel Component of EBV LMP1 Signalosome1R15CA252986-01A1 · under PAR-19-134WANG, LINGEAST TENNESSEE STATE UNIVERSITY, TN$439,428ZRG1
2021Molecular and Behavioral Impacts of Developmental OP Neurotoxicity1R15ES032959-01 · under PAR-19-134CARR, RUSSELL LMISSISSIPPI STATE UNIVERSITY, MS$436,465ZRG1
2021Mitochondrial Aging Promotes Inflammation1R15AG068957-01A1 · under PAR-19-134PANNEERSEELAN-BHARATH, LEENAMERRIMACK COLLEGE, MA$434,151ZRG1
2021THE VIRTUAL PROMOTORAS PROGRAM: DEVELOPMENT AND FEASIBILITY OF AN mHEALTH INTERVENTION TO PROMOTE SEXUAL HEALTH AND HEALTHCARE ACCESS AMONG YOUNG LATINA WOMEN IN THE US SOUTH1R15NR019690-01A1 · under PAR-19-134MORALES-ALEMAN, MERCEDES MARGARITAUNIVERSITY OF ALABAMA IN TUSCALOOSA, AL$430,947HHD
2021HIV infection-induced mitochondrial dysfunction and premature T cell aging1R15AG069544-01A1 · under PAR-19-134YAO, ZHI Q.EAST TENNESSEE STATE UNIVERSITY, TN$427,618HIVD
2021Novel mechanisms of arterial contractility regulation by statins1R15HL156138-01A1 · under PAR-19-134HASAN, RAQUIBULMERCER UNIVERSITY MACON, GA$424,500IVPP
2021Gender-specific Role of ATM in the Heart1R15HL156214-01A1 · under PAR-19-134SINGH, KRISHNAEAST TENNESSEE STATE UNIVERSITY, TN$423,196ZRG1
2021Lipase Maturation Factor 1 in Hypertriglyceridemia1R15HL154071-01A1 · under PAR-19-134PETERFY, MIKLOSWESTERN UNIVERSITY OF HEALTH SCIENCES, CA$423,000MCE
2021Demonstrating the mechanism of Nairovirus translation strategy1R15AI154949-01A1 · under PAR-19-134MIR, MOHAMMAD AWESTERN UNIVERSITY OF HEALTH SCIENCES, CA$423,000ZRG1
2021Mechanistic studies of cognition impairment in Angelman Syndrome2R15MH101703-03 · under PAR-19-134BI, XIAONINGWESTERN UNIVERSITY OF HEALTH SCIENCES, CA$423,000ZRG1
2021Combining Experiments and Computer Simulation to Improve the Stem Cell Differentiation Process1R15EB030842-01 · under PAR-19-134BOWLING, ALAN PAULUNIVERSITY OF TEXAS ARLINGTON, TX$418,653ZRG1
2021Maternal Health Care Utilization and Morbidity: The First 24 Months1R15HD101793-01A1 · under PAR-19-134AHRENS, KATHERINEUNIVERSITY OF SOUTHERN MAINE, ME$408,684HSOD
2021Targeting the Structurally Conserved Portal Protein as a Strategy to Develop a First-In-Class Broad-Spectrum Herpesvirus Antiviral Drug, PORT 11R15AI152023-01A1 · under PAR-19-134VISALLI, ROBERT J.MERCER UNIVERSITY MACON, GA$407,629ZRG1
2021Respiratory dysfunction in Alzheimer's disease and its link to oxidative damage within the brain stem.1R15AG065927-01A1 · under PAR-19-134OSTROWSKI, TIM D.A.T. STILL UNIVERSITY OF HEALTH SCIENCES, MO$387,403ZRG1
2021Novel dual-targeted inhibitors of EGFR and aurora kinase for lung cancer1R15CA246256-01A1 · under PAR-19-134KURUP, SONALIFERRIS STATE UNIVERSITY, MI$377,805ZRG1
2021Elucidating the Functions of the Essential Polyamine Putrescine for Proliferation and Survival of Leishmania Parasites1R15AI151980-01A1 · under PAR-19-134ROBERTS, SIGRID CHRISTIANEPACIFIC UNIVERSITY, OR$376,572ZRG1
2021Discovery of Novel Nontuberculous Inhibitors1R15AI164443-01 · under PAR-19-134NORTH, ELTON JEFFREYCREIGHTON UNIVERSITY, NE$363,750ZRG1
2021Nuclear Transport of Extracellular Vesicle Biomaterials1R15CA252990-01A1 · under PAR-19-134LORICO, AURELIORAPPA, GERMANATOURO UNIVERSITY OF NEVADA, NV$275,000ZRG1
2020Controlled Release of Multiple Drugs from Electrospun Fiber Membranes in the Local Treatment of Glioblastoma1R15CA252987-01 · under PAR-19-134STECKL, ANDREW JULESUNIVERSITY OF CINCINNATI, OH$481,543ZRG1
2020Attenuation correction strategies for myocardial perfusion imaging using dual-gated SPECT1R15HL150708-01A1 · under PAR-19-134JIN, MINGWUUNIVERSITY OF TEXAS ARLINGTON, TX$472,225ZRG1
2020Synthesis and optimization of antibody:DNAi conjugates targeting the MYC G41R15CA249793-01 · under PAR-19-134BROOKS, TRACY ANNSTATE UNIVERSITY OF NY,BINGHAMTON, NY$469,648SBCA
2020Selective HDAC6 inhibition deceases B cell activation in systemic lupus erythematosus1R15AI152022-01 · under PAR-19-134REILLY, CHRISTOPHER MICHAELVIRGINIA POLYTECHNIC INST AND ST UNIV, VA$466,545ZRG1
2020Phospho-Regulated AMPAR Trafficking by Oxidative Stress in the Aged Brain1R15NS116641-01A1 · under PAR-19-134JACKSON, DARRELL AWASHINGTON STATE UNIVERSITY, WA$459,000ZRG1
2020Novel Approaches to the Modulation of Protease-Activated Receptor (PAR) Signaling2R15HL127636-02 · under PAR-19-134DOCKENDORFF, CHRISTOPHERMARQUETTE UNIVERSITY, WI$455,662BBM
2020In vivo efficacy evaluation of novel melanoma actives1R15CA249788-01 · under PAR-19-134MINOND, DMITRIYNOVA SOUTHEASTERN UNIVERSITY, FL$453,399ZRG1
2020Ontogeny of the pre-pharyngeal swallow: effect of dietary texture-modification on the development of tongue kinematics and performance1R15HD101984-01 · under PAR-19-134WILLIAMS, SUSAN HOHIO UNIVERSITY ATHENS, OH$453,000MFSR
2020Effect of zinc on tPA induced thrombolysis1R15NS115080-01A1 · under PAR-19-134LI, YANG VOHIO UNIVERSITY ATHENS, OH$453,000ZRG1
2020Cell-specific blockage of TLR activation: A new strategy for addressing inflammatory disorders1R15AI149755-01 · under PAR-19-134TUMEY, LAWRENCESTATE UNIVERSITY OF NY,BINGHAMTON, NY$450,480SBCB
2020Anatomical and Molecular Investigation of Microenvironments that Influence B Lymphocytes1R15AI154245-01 · under PAR-19-134MANILAY, JENNIFER OSPENCER, JOEL A.UNIVERSITY OF CALIFORNIA, MERCED, CA$450,192ZRG1
2020CYCLOOXYGENASE-2 SIGNALING IN CELL SENESCENCE AND ITS ROLE IN CHEMOTHERAPY-INDUCED LONG-TERM ADVERSE SEQUELAE1R15CA246429-01 · under PAR-19-134SHIM, MINSUBMIDWESTERN UNIVERSITY (GLENDALE AZ), AZ$450,000CSRS
2020CHOLINERGIC MODULATION OF XII MOTONEURONS AND XII PREMOTONEURONS1R15HL148870-01A1 · under PAR-19-134REVILL, ANN LOUISEMIDWESTERN UNIVERSITY (GLENDALE AZ), AZ$447,700ZRG1
2020A detailed exploration of the physical and biochemical properties that contribute to RNA thermometer activity1R15AI147238-01A1 · under PAR-19-134MURPHY, ERIN ROHIO UNIVERSITY ATHENS, OH$447,390ZRG1
2020Role of Adipocyte Na/K-ATPase Signaling in the Development and Progression of Uremic Cardiomyopathy By Altering Adipocyte Phenotype1R15HL150721-01A1 · under PAR-19-134SODHI, KOMALMARSHALL UNIVERSITY, WV$444,000ZRG1
2020Hemodynamic mechanisms of impaired recovery and progression of renal disease following AKI in preexisting CKD states1R15HL154067-01 · under PAR-19-134POLICHNOWSKI, AARON JAMESEAST TENNESSEE STATE UNIVERSITY, TN$444,000HM
2020Sex-specific PACAP regulation of prefrontal-amygdala circuits and fear memory1R15MH118601-01A1 · under PAR-19-134GILMARTIN, MARIEKE RHEARING, MATTHEW CARLMARQUETTE UNIVERSITY, WI$443,810BRLE
2020Aryl hydrocarbon receptor regulation of energy metabolism1R15ES030556-01A1 · under PAR-19-134TISCHKAU, SHELLEY ASOUTHERN ILLINOIS UNIVERSITY SCH OF MED, IL$442,500ZRG1
2020Data-Driven Identification of Costly Multi-Morbidity Groupings and their Progression1R15AG067232-01 · under PAR-19-134MADLOCK-BROWN, CHARISSE RENEEUNIVERSITY OF TENNESSEE HEALTH SCI CTR, TN$435,338SSPB
2020Regulation of Arterial Function by Apelin/APJ Receptor Mechanisms2R15HL124338-02A1 · under PAR-19-134SUN, CHENGWENNORTH DAKOTA STATE UNIVERSITY, ND$435,000ZRG1
2020Discovery of Disulfiram as an Anti-MRSA Antibiotic Adjuvant1R15AI151970-01 · under PAR-19-134LONG, TIMOTHY EDWARDMARSHALL UNIVERSITY, WV$434,180ZRG1
2020Patients Perceptions of Electronic Health Record use during initial oncology outpatient clinic visits1R15NR018965-01 · under PAR-19-134ASAN, ONURTHE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGY, NJ$430,999NRCS
2020Hyperoxia-induced KV channel regulation in an aging mouse model1R15AG064674-01A1 · under PAR-19-134PANGULURI, SIVA KUMARUNIVERSITY OF SOUTH FLORIDA, FL$430,649ZRG1
2020Mechanistic Assessment of Osteopathic Manipulation inRelieving Migraine Headache Using a Novel Translational Rodent Model1R15AT011097-01 · under PAR-19-134XIE, YANHUANEW YORK INST OF TECHNOLOGY, NY$428,400ZAT1
2020Thyroid hormone regulation of cardiomyocyte T-tubule structureand function1R15HL154068-01 · under PAR-19-134OJAMAA, KAIE MARGAREETANEW YORK INST OF TECHNOLOGY, NY$428,386ZRG1
2020Manipulation of the SUMO Machinery by EBV LMP11R15CA246552-01 · under PAR-19-134BENTZ, GRETCHEN LMERCER UNIVERSITY MACON, GA$424,500ZRG1
2020Uptake of Mercury at the Basolateral Membrane of Isolated Proximal Tubules1R15ES030867-01A1 · under PAR-19-134BRIDGES, CHRISTY CMERCER UNIVERSITY MACON, GA$424,500ZRG1
2020Targeting Serotonin 5-HT1A and 5-HT7 Receptors to Prevent Audiogenic Seizures and Correct Translationally Valid EEG Phenotypes in a Juvenile Fmr1 Knock-Out Mouse Model of Fragile X Syndrome1R15NS118352-01 · under PAR-19-134CANAL, CLINTON EMERCER UNIVERSITY MACON, GA$424,499ZRG1
2020Olfactory ensheathing cells and microglia contributions to axon removal in the olfactory system.1R15DC018424-01A1 · under PAR-19-134RODRIGUEZ-GIL, DIEGO JAVIEREAST TENNESSEE STATE UNIVERSITY, TN$423,196ZRG1
2020Risk for Gestational Diabetes: A Condition of Abdominal Fatness or Sedentariness?1R15HD102957-01 · under PAR-19-134INGRAM, KATHERINE HEIMBURGERKENNESAW STATE UNIVERSITY, GA$406,257MCE
2020Homeostatic and Hedonic Components Involved in NOP Regulation of Energy Homeostasis2R15DA024314-04 · under PAR-19-134WAGNER, EDWARD JWESTERN UNIVERSITY OF HEALTH SCIENCES, CA$394,427ZRG1
2020Temporal ontogeny of epileptogenesis in a model of adult-onset, spontaneous seizures1R15NS115049-01 · under PAR-19-134ISGOR, CEYLANFLORIDA ATLANTIC UNIVERSITY, FL$389,791ZRG1
2020Combinatorial biosynthesis and metabolism studies of novel tetracenomycins1R15CA252830-01 · under PAR-19-134NYBO, ERICFERRIS STATE UNIVERSITY, MI$385,406SBCB
2020Cortical noise hypothesis: inhibitory mechanisms of motor population coding and dysfunction"1R15NS116742-01 · under PAR-19-134SHEW, WOODROW L.UNIVERSITY OF ARKANSAS AT FAYETTEVILLE, AR$360,398ZRG1
2020Glial Cells and Polyamine Signaling in the Central Nervous System1R15NS116478-01 · under PAR-19-134SKATCHKOV, SERGUEI NUNIVERSIDAD CENTRAL DEL CARIBE, PR$355,444ZRG1
2020In Vitro Analysis of the Effects of Acute and Chronic Phthalate Exposures on Leydig Cell Testosterone Production, and the Molecular Mechanisms Involved1R15ES032102-01 · under PAR-19-134TRAORE, KASSIMCAMPBELL UNIVERSITY, NC$312,493CMIR
2020Studies examining quantitative in vivo imaging of breast cancer-targeted, therapeutic human mast cells1R15CA246430-01A1 · under PAR-19-134KEPLEY, CHRIS LUNIVERSITY OF NORTH CAROLINA GREENSBORO, NC$263,686ZRG1
2020DO TELL - Digitized Stories to Bridge the Gap Between Patient and Provider Perceptions of Disease Self-Management Challenges1R15AG063087-01A1 · under PAR-19-134FRITZ, HEATHER ANNWAYNE STATE UNIVERSITY, MI$86,007CMPC

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