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NIH funding notice PAR-25-336

Toward Translation of Nanotechnology Cancer Interventions (TTNCI; R01 Clinical Trial Not Allowed)

Open. Closes November 15, 2027.

Posted
December 16, 2024
Close date
November 15, 2027
Activity codes
R01
Institutes taking part
NCI

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

  1. Reissues: PAR-22-071 Toward Translation of Nanotechnology Cancer Interventions (TTNCI) (R01 Clinical Trial Not Allowed)
  2. 2 steps back: PAR-20-116 Toward Translation of Nanotechnology Cancer Interventions (TTNCI) (R01 Clinical Trial Not Allowed)

Who won it before

22 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $14,238,409 in first-year total cost, median $608,697.

Most frequent study sections

  1. Special Emphasis Panel[ZRG1 IMST-U (55)]7
  2. Special Emphasis Panel[ZRG1 MCST-U (55)]7
  3. Special Emphasis Panel[ZRG1 IMST-A (55)]4
  4. Special Emphasis Panel[ZRG1 IMST-M (55)]4

Most frequent institutions

  1. UNIVERSITY OF TX MD ANDERSON CAN CTR2
  2. CEDARS-SINAI MEDICAL CENTER1
  3. EMORY UNIVERSITY1
  4. FRED HUTCHINSON CANCER RESEARCH CENTER1
  5. MASSACHUSETTS GENERAL HOSPITAL1
Competing awards under PAR-25-336 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2025Translational development of osteosarcoma (OS) extracellular vesicle (EV) matrix metalloproteinase (MMP) Activity Assay for assessing patient treatment responses1R01CA298883-01 · under PAR-22-071JONAS, STEVEN JOHNTSENG, HSIAN-RONGZHU, YAZHENUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$2,097,875ZRG1
2025Interstitial Chemophototherapy as an Intervention in Locally Advanced Pancreatic Cancer1R01CA298877-01 · under PAR-22-071LIU, TRACY WLOVELL, JONATHAN FSHAFIRSTEIN, GALSTATE UNIVERSITY OF NEW YORK AT BUFFALO, NY$677,176ZRG1
2024Designer extracellular vesicles for cancer therapy1R01CA284182-01A1 · under PAR-22-071XU, XIAOWEIUNIVERSITY OF PENNSYLVANIA, PA$662,946ZRG1
2024Development of novel nanotherapeutics to overcome therapy resistance using canine brain tumor as a spontaneous model1R01CA294557-01 · under PAR-22-071LI, YUANPEIUNIVERSITY OF CALIFORNIA AT DAVIS, CA$634,743ZRG1
2023Next Gen Targeted nanoparticles for Inhibiting Gli2 in Bone Metastatic Tumors1R01CA264508-01A1 · under PAR-22-071DUVALL, CRAIG LEWISRHOADES (STERLING), JULIE AVANDERBILT UNIVERSITY MEDICAL CENTER, TN$667,924ZRG1
2023Chip-Scale Intraoperative Optical Navigation with Immunotargeted Upconverting Nanoparticles1R01CA278672-01A1 · under PAR-22-071ANWAR, MEKHAILCOHEN, BRUCE EUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$655,333ZRG1
2023Targeted RNA delivery using ribonucleoprotein1R01CA268985-01A1 · under PAR-22-071GAO, XIAOHUUNIVERSITY OF WASHINGTON, WA$604,082ZRG1
2023Targeting tumor microenvironment by nanoimmunodrugs for glioma treatment1R01CA284247-01 · under PAR-22-071LJUBIMOV, ALEXANDER VCEDARS-SINAI MEDICAL CENTER, CA$577,033ZRG1
2023Engineering In Vivo Chimeric Antigen Receptor Macrophages (CARMs) using mRNA-exosomes for Cancer Immunotherapy1R01CA284108-01 · under PAR-22-071JIANG, WENKIM, BETTYUNIVERSITY OF TX MD ANDERSON CAN CTR, TX$567,816ZRG1
2023Customized nanofibers with preferential lung-targeting properties for treating metastatic pulmonary tumors1R37CA278671-01 · under PAR-22-071BELLAT, VANESSAWEILL MEDICAL COLL OF CORNELL UNIV, NY$511,558ZRG1
2022Toward translation of a plant virus-based in situ vaccination nanotechnology1R01CA274640-01 · under PAR-20-116FIERING, STEVENRANJAN, ASHISHSTEINMETZ, NICOLE FRANZISKAUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$649,918ZRG1
2022Pre-IND Development of Polymeric Micelles with Dual Drug Payloads for HCC Therapy1R01CA257842-01A1 · under PAR-20-116CHOW, DIANA S-L.LI, CHUNYANG, PEIYINGUNIVERSITY OF TX MD ANDERSON CAN CTR, TX$642,984ZRG1
2022Towards Translation of MU-CN29: New Therapeutic Nanoparticle for Drug-Resistant NSCLC1R01CA274677-01 · under PAR-20-116KANNAN, RAGHURAMANUNIVERSITY OF MISSOURI-COLUMBIA, MO$622,068ZRG1
2022Toward Translation of an Immunotherapeutic Nanomedicine for Neuroblastoma1R01CA274675-01 · under PAR-20-116WILSON, JOHN TANNERVANDERBILT UNIVERSITY, TN$604,335ZRG1
2021High throughput nanoplasmonic exosome testing (NEXT) of immunotherapies in bladder cancer1R01CA264363-01 · under PAR-20-116CASTRO, CESAR MLEE, HAKHOMASSACHUSETTS GENERAL HOSPITAL, MA$662,338ZRG1
2021TOWARD TRANSLATION OF NANFORMULATED PACLITAXEL-PLATINUM COMBINATION1R01CA264488-01 · under PAR-20-116KABANOV, ALEXANDER VUNIV OF NORTH CAROLINA CHAPEL HILL, NC$613,059ZRG1
2021Systemic delivery of siRNA by Nanosac for checkpoint blockade immunotherapy of head and neck squamous cell cancer1R01CA258737-01 · under PAR-20-116KRON, STEPHEN J.YEO, YOONPURDUE UNIVERSITY, IN$602,006ZRG1
2021Rapid and affordable magneto-nanosensors for ctDNA-guided lung cancer management1R01CA257843-01A1 · under PAR-20-116WANG, SHAN X.STANFORD UNIVERSITY, CA$573,461ZRG1
2021Development of a novel biodegradable inorganic nanoparticle therapeutic for cancer1R01CA257851-01 · under PAR-20-116KIM, WILLIAM Y.LI, ZIBOXIE, JINUNIVERSITY OF GEORGIA, GA$552,591ZRG1
2021Development of multifunctional drug and immune modulator delivery nanoparticles for the treatment of cancer patients with comorbid atherosclerosis1R01CA257861-01 · under PAR-20-116YANG, LILYEMORY UNIVERSITY, GA$542,085ZRG1
2021Oligo(lactic acid)n-Prodrug Nanomedicines for Combination Therapy1R01CA257837-01 · under PAR-20-116KWON, GLEN S.UNIVERSITY OF WISCONSIN-MADISON, WI$347,945ZRG1
2021Developing macrophage reprogramming mRNA nanocarriers for initial clinical testing1R01CA263524-01 · under PAR-20-116STEPHAN, MATTHIASFRED HUTCHINSON CANCER RESEARCH CENTER, WA$169,133ZRG1

Data: Grants.gov's daily extract and NIH's notice pages and award files, in ScienceGraph release conductgrants-2026-11-09-0.1.0. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.

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