The notices it replaced
- Reissues: PAS-13-031 Stimulating Hematology Investigation: New Endeavors (SHINE) (R01)
- 2 steps back: PAS-10-046 Stimulating Hematology Investigation: New Endeavors (SHINE) (R01)
Replaced by PAS-19-105.
Who won it before
76 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $26,042,180 in first-year total cost, median $352,032.
Most frequent study sections
- Molecular and Cellular Hematology Study Section[MCH]51
- Development - 2 Study Section[DEV2]3
- Special Emphasis Panel[ZRG1 VH-N (02)]3
- Integrative Nutrition and Metabolic Processes Study Section[INMP]2
- Special Emphasis Panel[ZRG1 VH-B (02)]2
Most frequent institutions
- STANFORD UNIVERSITY5
- UNIVERSITY OF FLORIDA5
- CINCINNATI CHILDRENS HOSP MED CTR4
- FRED HUTCHINSON CANCER RESEARCH CENTER4
- INDIANA UNIVERSITY INDIANAPOLIS4
| FY | Project | PIs | Institution | First-year cost | Study section |
|---|---|---|---|---|---|
| 2019 | The molecular pathophysiology of the congenital dyserythropoietic anemias1R01HL148333-01 | KHORIATY, RAMI | UNIVERSITY OF MICHIGAN AT ANN ARBOR, MI | $614,718 | MCH |
| 2019 | Regulation of Erythroid Cell Progenitors by the Nuclear Receptor Transcription Factor VDR2R01DK102945-05A1 | BARON, MARGARET H | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY | $585,111 | ZRG1 |
| 2019 | Roles and therapeutic potential of CD150high niche-associated regulatory T cells in bone marrow injury and engraftment1R01HL145154-01A1 | FUJISAKI, JOJI | COLUMBIA UNIVERSITY HEALTH SCIENCES, NY | $456,642 | TTT |
| 2019 | Macrophage regulation of the erythron1R01DK119285-01A1 | ELLIOTT, MICHAEL RUSTYPALIS, JAMES | UNIVERSITY OF ROCHESTER, NY | $455,457 | MCH |
| 2019 | Molecular mechanisms underlying clonal expansion of hematopoietic stem cells1R01HL150624-01 | LIU, YAN | INDIANA UNIVERSITY INDIANAPOLIS, IN | $393,750 | MCH |
| 2019 | The Metabolic Regulation of Hematopoietic Stem Cell Function1R01DK118745-01A1 | MORRISON, SEAN J | UT SOUTHWESTERN MEDICAL CENTER, TX | $364,500 | DEV2 |
| 2019 | The role of DNMT3A mutations in clonal heterogeneity and evolution of hematopoiesis1R01DK121831-01 | GURYANOVA, OLGA A | UNIVERSITY OF FLORIDA, FL | $343,125 | MCH |
| 2019 | Osteomacs and megakaryocytes interact to regulate hematopoietic stem cell function1R01DK118782-01A1 | KACENA, MELISSA ASROUR, EDWARD F | INDIANA UNIVERSITY INDIANAPOLIS, IN | $317,000 | MCH |
| 2019 | Selenium, Selenoproteins, and Stress Erythropoiesis1R01DK119865-01A1 | PAULSON, ROBERT FRANKPRABHU, KUMBLE SANDEEP | PENNSYLVANIA STATE UNIVERSITY, THE, PA | $316,100 | MCH |
| 2019 | Extramedullary Hematopoiesis and the Splenic Niche1R01DK121117-01 | SCOTT, EDWARD W | UNIVERSITY OF FLORIDA, FL | $274,500 | MCH |
| 2018 | Maintenance and expansion of long-term hematopoietic stem cells1R01HL141759-01 | KLEIN, PETER S | UNIVERSITY OF PENNSYLVANIA, PA | $540,335 | DEV2 |
| 2018 | Developing Effective Approaches to Extend Hematopoietic Healthspan by Targeting Cell-extrinsic and Cell-intrinsic Alterations at Middle Age1R01DK118072-01 | TROWBRIDGE, JENNIFER JEAN | JACKSON LABORATORY, ME | $473,290 | MCH |
| 2018 | Defining the Self-Renewal Program in Human Hematopoietic Stem Cells2R01DK100959-04A1 | MIKKOLA, HANNA KATRI ANNIKKI | UNIVERSITY OF CALIFORNIA LOS ANGELES, CA | $432,674 | ZRG1 |
| 2018 | Hematopoietic Stem Cell Aging1R01DK117481-01 | CHEN, DANICA | UNIVERSITY OF CALIFORNIA BERKELEY, CA | $427,075 | ASG |
| 2018 | Modulating HSC-niche interactions to understand aging and improve transplantation1R01HL147124-01 | NAKAUCHI, HIROMITSU | STANFORD UNIVERSITY, CA | $406,711 | MCH |
| 2018 | Improving the interaction of hematopoietic stem cells with the perivascular niche to promote engraftment1R01HL142998-01 | TAMPLIN, OWEN JAMES | UNIVERSITY OF ILLINOIS AT CHICAGO, IL | $399,750 | MCH |
| 2018 | Epigenetic, Transcriptional, and Microenvironmental Determinants of Human HSC Self-Renewal1R01HL142637-01 | MAJETI, RAVINDRA | STANFORD UNIVERSITY, CA | $397,048 | MCH |
| 2018 | Nutrient Sensing, Hematopoietic Stem Cell Metabolism and Aging1R01AG063404-01 | CHEN, DANICA | UNIVERSITY OF CALIFORNIA BERKELEY, CA | $392,500 | ZRG1 |
| 2018 | Mechanisms regulating the aging of HSC niches1R01DK112976-01A1 | FRENETTE, PAUL S | ALBERT EINSTEIN COLLEGE OF MEDICINE, INC, NY | $375,750 | MCH |
| 2018 | Cellular and molecular analyses of hematopoietic stem cell [HSC] interactions with bone marrow niches to improve HSC engraftment for transplantation and tolerance induction1R01DK115600-01A1 | WEISSMAN, IRVING L. | STANFORD UNIVERSITY, CA | $369,622 | TTT |
| 2018 | Valine as a Metabolic Modulator of Hematopoiesis1R01DK116944-01 | NAKAUCHI, HIROMITSU | STANFORD UNIVERSITY, CA | $363,414 | MCH |
| 2018 | Defining the Niche-dependent Role of RNA Editing in Aged and MDS Hematopoietic Stem and Progenitor Cell Dysfunction2R01DK114468-02 | JAMIESON, CATRIONA HELEN MACLEOD | UNIVERSITY OF CALIFORNIA, SAN DIEGO, CA | $353,344 | MCH |
| 2018 | Protein Homeostasis in Hematopoietic Stem Cells1R01DK116951-01 | SIGNER, ROBERT A.J. | UNIVERSITY OF CALIFORNIA, SAN DIEGO, CA | $353,063 | MCH |
| 2018 | The roles of lipid metabolism in the maintenance of hematopoietic stem cells2R01DK098263-07 | ITO, KEISUKE | ALBERT EINSTEIN COLLEGE OF MEDICINE, INC, NY | $233,498 | ZRG1 |
| 2018 | Molecular mechanisms underlying clonal expansion of hematopoietic stem cells1R56DK119524-01 | LIU, YAN | INDIANA UNIVERSITY INDIANAPOLIS, IN | $150,000 | MCH |
| 2018 | Macrophage regulation of the erythron1R56DK119285-01 | ELLIOTT, MICHAEL RUSTYPALIS, JAMES | UNIVERSITY OF ROCHESTER, NY | $100,000 | MCH |
| 2018 | The role, mechanism and therapeutic potential of TET1 in MDS1R56DK120282-01 | CHEN, JIANJUN | BECKMAN RESEARCH INSTITUTE/CITY OF HOPE, CA | $100,000 | MCH |
| 2018 | Intrinsic and extrinsic control of erythropoietic maturation2R56DK102260-05 | BIEKER, JAMES J | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY | $99,999 | MCH |
| 2018 | The metabolic regulation of hematopoietic stem cell function1R56DK118745-01 | MORRISON, SEAN J | UT SOUTHWESTERN MEDICAL CENTER, TX | $99,999 | DEV2 |
| 2018 | Mechanisms of Impaired Erythropoiesis in Post Burn Anemia of Critical Illness2R56DK097760-06 | MUTHUMALAIAPPAN, KUZHALI | LOYOLA UNIVERSITY CHICAGO, IL | $99,999 | SAT |
| 2018 | miR-223 regulates endothelial to hematopoietic transition1R56DK118728-01 | HIRSCHI, KAREN KEMPERNICOLI, STEFANIA | YALE UNIVERSITY, CT | $99,999 | MCH |
| 2017 | Single cell approach to uncovering factors regulating HSC division symmetry in vivo1R01DK115577-01 | ITO, KEISUKELIN, CHARLES P. | ALBERT EINSTEIN COLLEGE OF MEDICINE, INC, NY | $609,456 | ZRG1 |
| 2017 | NPM1 regulation of 2'-O-methylation in hematopoiesis and bone marrow failure disorder1R01DK115536-01 | PANDOLFI, PIER PAOLO | BETH ISRAEL DEACONESS MEDICAL CENTER, MA | $408,289 | MCH |
| 2017 | Novel regulation of Notch-induced HSPC expansion1R01DK110563-01A1 | BERNSTEIN, IRWIN D | FRED HUTCHINSON CANCER RESEARCH CENTER, WA | $396,000 | MCH |
| 2017 | Transcript decay regulates hematopoietic aging1R01DK115454-01 | CATIC, ANDRE | BAYLOR COLLEGE OF MEDICINE, TX | $356,625 | ZRG1 |
| 2017 | Defining the Niche-dependent Role of RNA Editing in Aged and MDS Hematopoietic Stem and Progenitor Cell Dysfunction1R01DK114468-01 | JAMIESON, CATRIONA HELEN MACLEOD | UNIVERSITY OF CALIFORNIA, SAN DIEGO, CA | $232,500 | MCH |
| 2017 | Defining the Self-Renewal Program in Human Hematopoietic Stem Cells2R56DK100959-04 | MIKKOLA, HANNA KATRI ANNIKKI | UNIVERSITY OF CALIFORNIA LOS ANGELES, CA | $226,470 | MCH |
| 2017 | Aging-induced Alterations in the Microenvironment as Drivers of Myeloid Lineage Skewing1R56DK112947-01A1 | TROWBRIDGE, JENNIFER JEAN | JACKSON LABORATORY, ME | $150,000 | MCH |
| 2016 | Regulation of Hematopoietic Progenitors by de novo DNA methylation2R01DK092883-05 · under PAS-13-031 | GOODELL, MARGARET A. | BAYLOR COLLEGE OF MEDICINE, TX | $568,203 | ZRG1 |
| 2016 | DEK Regulation of Hematopoietic Stem Cell Renewal, Fate, and Hematopoiesis1R01DK109188-01 · under PAS-13-031 | BROXMEYER, HAL E.MARKOVITZ, DAVID MICHAEL | INDIANA UNIVERSITY INDIANAPOLIS, IN | $512,978 | MCH |
| 2016 | Cdc42, hematopoietic stem cell polarity, and cell fate1R01DK104814-01A1 · under PAS-13-031 | ZHENG, YI | CINCINNATI CHILDRENS HOSP MED CTR, OH | $496,716 | ZRG1 |
| 2016 | Mesenchymal Stromal Cells Regulate Hematopoietic Stem Cell Aging1R01DK107413-01 · under PAS-13-031 | NAKADA, DAISUKE | BAYLOR COLLEGE OF MEDICINE, TX | $431,329 | CMAD |
| 2016 | Regulation of the telomerase RNA component in hematopoiesis1R01DK107716-01 · under PAS-13-031 | AGARWAL, SUNEET | BOSTON CHILDREN'S HOSPITAL, MA | $398,250 | MCH |
| 2016 | Signaling Pathways in MDS1R01DK107286-01A1 | LIN, SHUOSAKAMOTO, KATHLEEN M | STANFORD UNIVERSITY, CA | $363,278 | ZRG1 |
| 2016 | The molecular mechanism of clonal dominance in 5q(del) MDS1R01DK107615-01A1 · under PAS-13-031 | QIAN, ZHIJIAN | UNIVERSITY OF ILLINOIS AT CHICAGO, IL | $359,775 | MCH |
| 2016 | Rcor1 Regulates Myelomonocytic Progenitor Cell Fate1R01DK109694-01A1 | FLEMING, WILLIAM H | OREGON HEALTH & SCIENCE UNIVERSITY, OR | $346,500 | MCH |
| 2016 | U2AF1 mutations in myelodysplastic syndromes: from mechanism to therapy1R01DK103854-01A1 · under PAS-13-031 | BRADLEY, ROBERT K | FRED HUTCHINSON CANCER RESEARCH CENTER, WA | $341,375 | ZRG1 |
| 2016 | Hematopoietic Regulation via GATA Switches2R01DK068634-11 · under PAS-13-031 | BRESNICK, EMERY H | UNIVERSITY OF WISCONSIN-MADISON, WI | $340,434 | MCH |
| 2016 | The Role of Long Noncoding RNA in Hematopoiesis1R01DK110108-01 · under PAS-13-031 | HUANG, SUMING | UNIVERSITY OF FLORIDA, FL | $337,500 | MCH |
| 2016 | Metabolic regulation of hematopoietic stem cells2R01DK092722-05 · under PAS-13-031 | QU, CHENG-KUI | EMORY UNIVERSITY, GA | $273,000 | MCH |
| 2015 | MicroRNAs and hematopoietic differentiation2R01DK068348-11 · under PAS-13-031 | LODISH, HARVEY F | WHITEHEAD INSTITUTE FOR BIOMEDICAL RES, MA | $500,175 | MCH |
| 2015 | Regulation of hematopoietic stem cell self-renewal by GTPase activating protein signaling1R01DK102890-01A1 · under PAS-13-031 | FILIPPI, MARIE-DOMINIQUEMALIK, PUNAM | CINCINNATI CHILDRENS HOSP MED CTR, OH | $426,291 | ZRG1 |
| 2015 | Regulatory role of iron transport in stress and ineffective erythropoiesis1R01DK107670-01 · under PAS-13-031 | GINZBURG, YELENA | NEW YORK BLOOD CENTER, NY | $369,573 | MCH |
| 2015 | Role of Transcription Pausing in Hematopoietic Stem Cell Development1R01DK105287-01 · under PAS-13-031 | BAI, XIAOYING | UT SOUTHWESTERN MEDICAL CENTER, TX | $354,487 | MCH |
| 2015 | Role of the Hypoxia-Inducible Factor-1alpha in Myelodysplastic Syndromes1R01DK105014-01 · under PAS-13-031 | HUANG, GANG | CINCINNATI CHILDRENS HOSP MED CTR, OH | $351,000 | MCH |
| 2015 | EPIGENTIC REGULATION OF HEMATOPOIETIC STEM CELL FUNCTION AND TRANSFORMATION1R01DK102428-01A1 · under PAS-13-031 | CHALLEN, GRANT ANTHONY | WASHINGTON UNIVERSITY, MO | $343,125 | MCH |
| 2015 | Roles of Neogenin and Matriptase-2 in Hemojuvelin-Mediated Hepcidin Expression1R01DK102791-01A1 · under PAS-13-031 | ZHANG, AN-SHENG | OREGON HEALTH & SCIENCE UNIVERSITY, OR | $332,264 | MCH |
| 2015 | Regulation of hematopoietic stem and progenitor cell fate determination by Dpy301R01DK105531-01A1 · under PAS-13-031 | JIANG, HAO | UNIVERSITY OF ALABAMA AT BIRMINGHAM, AL | $330,750 | MCH |
| 2015 | Noncoding RNA-DNMT1 interactions in hematopoiesis1R01DK103858-01 · under PAS-13-031 | TENEN, DANIEL G | BETH ISRAEL DEACONESS MEDICAL CENTER, MA | $261,000 | MCH |
| 2015 | Quantitative Notch Signaling in Hematopoiesis1R56DK104063-01A1 · under PAS-13-031 | BERNSTEIN, IRWIN D | FRED HUTCHINSON CANCER RESEARCH CENTER, WA | $140,800 | MCH |
| 2015 | The role of a lincRNA in chromatin structure and hematopoiesis1R56DK101994-01A1 · under PAS-13-031 | HUANG, SUMING | UNIVERSITY OF FLORIDA, FL | $120,000 | ZRG1 |
| 2014 | Confounder-Corrected Quantitative MRI Biomarkers of Hepatic1R01DK100651-01 · under PAS-13-031 | REEDER, SCOTT B. | UNIVERSITY OF WISCONSIN-MADISON, WI | $698,355 | ZRG1 |
| 2014 | Uncovering the role for Msi2 in hematopoietic stem cells1R01DK101989-01A1 · under PAS-13-031 | KHARAS, MICHAEL | SLOAN-KETTERING INST CAN RESEARCH, NY | $394,706 | MCH |
| 2014 | Epigenetic and Cell Cycle Functions of Glucocorticoids in Erythropoietic Stress1R01DK100915-01A1 · under PAS-13-031 | SOCOLOVSKY, MERAV | UNIV OF MASSACHUSETTS MED SCH WORCESTER, MA | $361,812 | MCH |
| 2014 | Novel regulators of stress erythropoiesis2R01DK089439-04A1 · under PAS-13-031 | WOJCHOWSKI, DON MICHAEL | MAINEHEALTH, ME | $360,110 | MCH |
| 2014 | Dissection and Manipulation of the Cellular Response to Iron Restriction2R01DK079924-05A1 · under PAS-13-031 | GOLDFARB, ADAM N. | UNIVERSITY OF VIRGINIA, VA | $343,650 | INMP |
| 2014 | HRI-eIF2a Phosphorylation signaling in oxidative stress and erythropoiesis2R01DK087984-04A1 · under PAS-13-031 | CHEN, JANE-JANE | MASSACHUSETTS INSTITUTE OF TECHNOLOGY, MA | $339,300 | MCH |
| 2014 | Molecular Determinants of Asymmetric Division1R01DK099335-01A1 · under PAS-13-031 | REYA, TANNISHTHA | UNIVERSITY OF CALIFORNIA, SAN DIEGO, CA | $337,125 | MCH |
| 2014 | The role of emergency granulopoiesis in the pathogenesis of Fanconi Anemia1R01DK098812-01A1 · under PAS-13-031 | EKLUND, ELIZABETH ANN | NORTHWESTERN UNIVERSITY AT CHICAGO, IL | $336,038 | MCH |
| 2014 | Gradient Biomaterials to Investigate Niche Regulation of Hematopoiesis1R01DK099528-01A1 · under PAS-13-031 | HARLEY, BRENDAN A. | UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN, IL | $335,859 | BTSS |
| 2014 | ZIP Proteins and Iron Metabolism2R01DK080706-06 · under PAS-13-031 | KNUTSON, MITCHELL D | UNIVERSITY OF FLORIDA, FL | $314,986 | INMP |
| 2014 | BMP4 Dependent Stress Erythropoiesis Pathway in Short-term Radioprotection2R01DK080040-05A1 · under PAS-13-031 | PAULSON, ROBERT FRANK | PENNSYLVANIA STATE UNIVERSITY, THE, PA | $311,223 | MCH |
| 2014 | Epigenetic regulation by microRNA of MDS pathogenesis1R01DK100689-01 · under PAS-13-031 | ITO, KEISUKE | ALBERT EINSTEIN COLLEGE OF MEDICINE, NY | $250,500 | MCH |
| 2014 | Non-cell-autonomous hedgehog signaling in B lymphopoiesis1R01DK099188-01A1 · under PAS-13-031 | DESIDERIO, STEPHEN V | JOHNS HOPKINS UNIVERSITY, MD | $243,000 | MCH |
| 2014 | Molecular Pathogenesis of MDS1R01DK102759-01 · under PAS-13-031 | STARCZYNOWSKI, DANIEL | CINCINNATI CHILDRENS HOSP MED CTR, OH | $234,000 | MCH |
| 2014 | U2AF1 mutations in myelodysplastic syndromes: from mechanism to therapy1R56DK103854-01 · under PAS-13-031 | BRADLEY, ROBERT K | FRED HUTCHINSON CANCER RESEARCH CENTER, WA | $114,400 | ZRG1 |
Data: Grants.gov's daily extract and NIH's notice pages and award files, in ScienceGraph release conductgrants-2026-11-09-0.1.0. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.