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NIH funding notice PAS-18-730

New Directions in Hematology Research (SHINE-II) (R01 Clinical Trial Optional)

Closed on May 7, 2021.

Posted
March 29, 2018
Close date
May 7, 2021
Activity codes
Not stated on the notice page
Institutes taking part
Not stated on the notice page

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

Its page was not saved, so the notices it replaced are not known.

Who won it before

28 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $8,659,491 in first-year total cost, median $311,760.

Most frequent study sections

  1. Molecular and Cellular Hematology Study Section[MCH]12
  2. Basic Biology of Blood, Heart and Vasculature Study Section [BBHV]5
  3. Gene and Drug Delivery Systems Study Section[GDD]2
  4. Hemostasis, Thrombosis, Blood Cells and Transfusion Study Section[HTBT]2
  5. Special Emphasis Panel[ZRG1 VH-C (02)]2

Most frequent institutions

  1. MAYO CLINIC ROCHESTER3
  2. UNIVERSITY OF CALIFORNIA LOS ANGELES3
  3. BOSTON CHILDREN'S HOSPITAL2
  4. ALBERT EINSTEIN COLLEGE OF MEDICINE1
  5. ARKANSAS CHILDREN'S HOSPITAL RES INST1
Competing awards under PAS-18-730 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2022Towards Understanding Molecular Mechanisms of Human Hematopoietic Stem Cells' Quiescence1R01HL161567-01GHAFFARI, SAGHIICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY$338,000HTBT
2022Regulation of the lymphoid cell fate by Hoxa91R01AG076163-01MEDINA, KAY LYNNMAYO CLINIC ROCHESTER, MN$318,000BBHV
2022MYCT1 as a moderator for signaling between human HSC and their niche1R01HL162408-01MIKKOLA, HANNA KATRI ANNIKKIUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$312,000ZRG1
2022Role of BRD4 in Normal Hematopoiesis and Hematopoietic Stem Cell Biology1R01HL158081-01A1YANG, FENG-CHUNUNIVERSITY OF TEXAS HLTH SCIENCE CENTER, TX$310,000BBHV
2021Bone Marrow Spatial Transcriptomics to Enhance In Vitro Platelet Production1R01HL159106-01CANTOR, ALAN B.BOSTON CHILDREN'S HOSPITAL, MA$371,377BBHV
2021A bio-engineered hepatic niche for ex vivo expansion of HSCs1R01HL151720-01A1KHETANI, SALMAN RPAJCINI, KOSTANDINUNIVERSITY OF ILLINOIS AT CHICAGO, IL$319,800HBPP
2021Mapping human hematopoietic stem cell development1R01DK125097-01MIKKOLA, HANNA KATRI ANNIKKIUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$312,000ZRG1
2021Histone H2A.X signaling and chromatin remodeling in late erythropoiesis1R01HL158848-01BULGER, MICHAEL DUNIVERSITY OF ROCHESTER, NY$297,200BBHV
2021Regulators of von Willebrand Factor Levels1R01HL159399-01JAGADEESWARAN, PUDURUNIVERSITY OF NORTH TEXAS, TX$297,000HTBT
2021The role of m6A RNA modification as modulator of dsRNA induced cell-intrinsic innate immune responses in hematopoiesis1R01DK124788-01A1HALENE, STEPHANIEYALE UNIVERSITY, CT$294,800MCH
2021Identification of novel regulators of HSC specification and maturation1R01DK131445-01BOWMAN, TERESA VALBERT EINSTEIN COLLEGE OF MEDICINE, NY$286,464BBHV
2020Epigenetic regulation of thrombopoiesis1R01HL149751-01CHEN, TAIPINGSANTOS, MARGARIDAUNIVERSITY OF TX MD ANDERSON CAN CTR, TX$324,000HT
2020MicroRNA-based epigenetic approach to induce fetal hemoglobin1R01HL144641-01A1STARLARD-DAVENPORT, ATHENAUNIVERSITY OF TENNESSEE HEALTH SCI CTR, TN$318,302ZRG1
2020Single non-integrating RNA vector for gene editing and reprogramming of Fanconi anemia fibroblasts1R01HL147852-01A1DEVAUX, PATRICIAMAYO CLINIC ROCHESTER, MN$318,000GDD
2020Modulation of protein methylation to improve hematopoietic stem cell engraftment1R01HL152131-01BUNTING, KEVIN DPALLAS, DAVID CEMORY UNIVERSITY, GA$312,000MCH
2020Integrating Human Genetics and Single-Cell Functional Assays to Elucidate Mechanisms of Fetal Hemoglobin Regulation1R56DK125234-01SANKARAN, VIJAY GANESHBOSTON CHILDREN'S HOSPITAL, MA$311,520MCH
2020Mechanisms of Erythroid Remission in Diamond Blackfan Anemia (DBA)1R01HL150194-01FARRAR, JASON ELIARKANSAS CHILDREN'S HOSPITAL RES INST, AR$306,000MCH
2020Metabolic Control of Erythroid Differentiation1R01HL146528-01A1PAULSON, ROBERT FRANKPENNSYLVANIA STATE UNIVERSITY, THE, PA$305,003MCH
2020Chromatin State Alterations in Fanconi Anemia Hematologic Disease and Bone Marrow Failure1R01HL149907-01HOWLETT, NIALL GEORGEUNIVERSITY OF RHODE ISLAND, RI$302,450MCH
2020Mitochondria mediated intercellular metabolic coupling in bone marrow regeneration1R01DK124115-01CANCELAS, JOSE A.CINCINNATI CHILDRENS HOSP MED CTR, OH$279,840ZRG1
2019Bone Marrow Niche dysfunction in sickle cell disease1R01HL146632-01CARLESSO, NADIABECKMAN RESEARCH INSTITUTE/CITY OF HOPE, CA$346,000MCH
2019Image guided profiling of the native HSC niche1R01DK123216-01CAMARGO, FERNANDOLIN, CHARLES P.MASSACHUSETTS GENERAL HOSPITAL, MA$323,935MCH
2019Iron Catalyzed H2S and its Prevalence in Hemolytic and Iron Overload Disorders1R01HL148352-01HINE, CHRISTOPHER MICHAELCLEVELAND CLINIC LERNER COM-CWRU, OH$320,000MCH
2019Single non-integrating RNA vector for gene editing and reprogramming of Fanconi anemia fibroblasts1R56HL147852-01DEVAUX, PATRICIAMAYO CLINIC ROCHESTER, MN$318,000GDD
2019Manipulating the Stem Cell Epigenome to Improve Bone Marrow Transplantation1R01DK119231-01A1CHALLEN, GRANT ANTHONYWASHINGTON UNIVERSITY, MO$282,600MCH
2019Defining the mechanisms regulating MLLT3 expression in human hematopoietic stem cells1R01DK121557-01MIKKOLA, HANNA KATRI ANNIKKIUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$280,800ZRG1
2019Enhancing hematopoiesis through modulation of a histone methyltransferase: evaluating a new MLL1 gain-of-function animal model1R01DK120369-01A1ERNST, PATRICIAUNIVERSITY OF COLORADO DENVER, CO$279,900MCH
2019Critical role of NRF2 in globin gene regulation in sickle cell disease mouse models1R01DK119762-01A1ZHU, XINGGUOAUGUSTA UNIVERSITY, GA$274,500MCH

Data: Grants.gov's daily extract and NIH's notice pages and award files, in ScienceGraph release conductgrants-2026-11-09-0.1.0. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.

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