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NIH funding notice PAS-19-392

Small Research Grant Program for the Next Generation of Researchers in AD/ADRD Research: Area of Focus Basic Science (R03 Clinical Trials Not Allowed)

Closed on March 16, 2023.

Posted
October 7, 2019
Close date
March 16, 2023
Activity codes
Not stated on the notice page
Institutes taking part
Not stated on the notice page

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

Its page was not saved, so the notices it replaced are not known.

Who won it before

76 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $14,496,359 in first-year total cost, median $161,500.

Most frequent study sections

  1. Chronic Dysfunction and Integrative Neurodegeneration Study Section[CDIN]18
  2. Cellular and Molecular Biology of Glia Study Section[CMBG]8
  3. Cellular and Molecular Biology of Neurodegeneration Study Section[CMND]7
  4. Clinical Neuroscience and Neurodegeneration Study Section[CNN]5
  5. Cellular Mechanisms in Aging and Development Study Section[CMAD]4

Most frequent institutions

  1. ROSKAMP INSTITUTE, INC.5
  2. ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI4
  3. UNIVERSITY OF MARYLAND BALTIMORE3
  4. BAYLOR COLLEGE OF MEDICINE2
  5. CASE WESTERN RESERVE UNIVERSITY2
Competing awards under PAS-19-392 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2024Role of mitochondrial Complex I deficiency in Alzheimer disease and dementia1R03AG084940-01POLSTER, BRIAN MUNIVERSITY OF MARYLAND BALTIMORE, MD$311,000NOMD
2024Development of Novel γ-Secretase PET Agents for the Exploration of AD Pathology1R03AG081968-01A1XU, YULONGMASSACHUSETTS GENERAL HOSPITAL, MA$167,000EITN
2024Role of Y-family DNA polymerase Pol kappa in aging and Alzheimer's disease1R03AG081828-01A1PAUL, SHILPIPENNSYLVANIA STATE UNIV HERSHEY MED CTR, PA$166,800CMAD
2024Induction of Neutrophil Extracellular Traps by Beta-Amyloid Deposits in Cerebral Amyloid Angiopathy1R03AG085082-01SCHRADER, JOSEPH MUNIVERSITY OF RHODE ISLAND, RI$157,500ANIE
2024Enhancer RNAs and enhancer-centric gene regulatory networks in vascular dementia1R03AG084918-01DHARAP, ASHUTOSHUNIVERSITY OF SOUTH FLORIDA, FL$150,000BINP
2024New biomarkers for early Alzheimer's diagnosis and tauopathy differentiation1R03AG085058-01WU, LINGNORTH CAROLINA CENTRAL UNIVERSITY, NC$150,000CNN
2023Daily Memory Lapses and Sympathetic-Cardiovascular Dysfunction: Pathways to Prevention of Alzheimer's Disease and Related Dementias (ADRD)1R03AG083323-01GREANEY, JODYJANG, HEEJUNGCLEMSON UNIVERSITY, SC$318,574MESH
2023Patient specific computational modeling of fluid-structure interactions of cerebrospinal fluid for biomarkers in Alzheimer's disease1R03AG081836-01FILLINGHAM, PATRICKUNIVERSITY OF WASHINGTON, WA$303,614ZRG1
2023Behavioral and physiological measurements of hearing in mouse models of Alzheimer's Disease1R03AG081747-01DENT, MICHEAL LLAUER, AMANDA M.STATE UNIVERSITY OF NEW YORK AT BUFFALO, NY$177,156AUD
2023Integrative genomic analysis of adenosine-to-inosine editing in Alzheimer's disease1R03AG080170-01BREEN, MICHAEL SICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY$166,240GHD
2023Influence of APOE4 genotype on microglial pathobiology and tau pathology after repetitive mTBI1R03AG080415-01OJO, JOSEPH OROSKAMP INSTITUTE, INC., FL$163,440CMBG
2023Bacterial triggers of neural inflammation.1R03AG080175-01BURBERRY, AARONCASE WESTERN RESERVE UNIVERSITY, OH$161,000CDIN
2023Developing and Validating a Novel Tau Toxicity Model in the Budding Yeast1R03AG080423-01DANG, WEIWEIBAYLOR COLLEGE OF MEDICINE, TX$160,000CMAD
2023Structural characterization of APP family proteins1R03AG081787-01PETROU, VASILEIOS IRUTGERS BIOMEDICAL AND HEALTH SCIENCES, NJ$157,000MSFB
2023A Breakdown of Memory Replay: Elucidating the Relationship Between Sleep and Alzheimer's Disease from Surface Electroencephalography1R03AG080427-01MCCONNELL, BRICE VUNIVERSITY OF COLORADO DENVER, CO$155,500CNN
2023Reduced allelic dosage of CLP1 attenuates cognitive dysfunction and pathological burden in transgenic mouse models of Alzheimer’s disease1R03AG080287-01SCHAFFER, ASHLEIGH ECASE WESTERN RESERVE UNIVERSITY, OH$155,205CDIN
2023Effects of mild traumatic brain injury in a mouse model of cerebral amyloid angiopathy1R03AG081865-01ROBISON, LISA SUZANNENOVA SOUTHEASTERN UNIVERSITY, FL$154,000CDIN
2023Cerebrovascular endothelial cilia in the pathogenesis and therapy of Alzheimer's disease1R03AG080418-01ABOUALAIWI, WISSAMUNIVERSITY OF TOLEDO HEALTH SCI CAMPUS, OH$149,050ZRG1
2023Astrocytic exocytosis of ATP in amyloid pathology and Alzheimer's disease1R03AG083363-01CAI, WEIKANGNEW YORK INST OF TECHNOLOGY, NY$119,000CMBG
2022Assessing effects of manipulation of expression of kinesins in a mouse modelof Alzheimer's disease1R03AG073870-01A1PUTHANVEETTIL, SATHYAUNIVERSITY OF FLORIDA, FL$386,400CDIN
2022Deciphering Ang2/Tie2 signaling regulation of BBB disruption and neuroinflammation in Alzheimers disease1R03AG073833-01A1KIM, MINAHCOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$328,833ZRG1
2022Investigation of sirtuin 1 expression in mice model of Alzheimer's disease over age1R03AG076389-01WANG, CHANGNINGMASSACHUSETTS GENERAL HOSPITAL, MA$323,760CDIN
2022Role of pericytes in postoperative neurocognitive disorder during aging1R03AG078882-01YANG, TINGDUKE UNIVERSITY, NC$322,000CDIN
2022DNA Nanostructures as siRNA Delivery Vehicles for Alzheimer's Therapy1R03AG076599-01CHANDRASEKARAN, ARUN RICHARDSTATE UNIVERSITY OF NEW YORK AT ALBANY, NY$312,417ZRG1
2022Analysis of Nrf1 pathway in Alzheimer's Disease1R03AG073884-01RADHAKRISHNAN, SENTHIL KUMARVIRGINIA COMMONWEALTH UNIVERSITY, VA$310,500CMND
2022Ffar4 attenuates neuroinflammation in Alzheimer's Disease1R03AG078686-01MURPHY, KATHERINE AUNIVERSITY OF MINNESOTA, MN$310,000CDIN
2022Development of a novel gene therapy for the treatment of tauopathy1R03AG075597-01A1KHAN, MOHAMMAD MOSHAHIDPOURMOTABBED, TAYEBEHUNIVERSITY OF TENNESSEE HEALTH SCI CTR, TN$308,000CDIN
2022Directed evolution of tissue inhibitor of metalloproteinase 3 (TIMP-3) to develop novel Alzheimer’s disease (AD) therapeutics1R03AG070511-01A1RAEESZADEH SARMAZDEH, MARYAMUNIVERSITY OF NEVADA RENO, NV$299,975DDNS
2022Contributions of Iron Regulatory Proteins and Ferroptosis to Neurodegeneration1R03AG077299-01MONTGOMERY, MCKALEOKLAHOMA STATE UNIVERSITY STILLWATER, OK$292,657NOMD
2022Time-restricted feeding (TRF) for prevention of age-related vascular cognitive impairment and dementia1R03AG070479-01A1TARANTINI, STEFANOUNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR, OK$290,000CDIN
2022Cerebrovascular contributions to cognitive impairment in Lewy body dementias1R03AG075408-01RYMAN, SEPHIRALOVELACE BIOMEDICAL RESEARCH INSTITUTE, NM$181,000CNN
2022Mechanisms underlying glutamate dyshomeostasis in Alzheimer's disease1R03AG070766-01A1ROSENBERG, PAUL ALLENBOSTON CHILDREN'S HOSPITAL, MA$177,000SYN
2022THE ROLE OF PTEN IN MICROGLIAL PATHOBIOLOGY AFTER EXPOSURE TO REPETITIVE MILD TBI1R03AG078772-01OJO, JOSEPH OROSKAMP INSTITUTE, INC., FL$163,440CMBG
2022The role of PPARγ in microglia pathobiologyafter exposure to repetitive mild traumatic brain injury1R03AG075365-01OJO, JOSEPH OROSKAMP INSTITUTE, INC., FL$163,439CMBG
2022Understanding how human brain vascular cells mediate genetic risk for Alzheimer's disease1R03AG079029-01YANG, ANDREW CHRISUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$161,500GHD
2022Dysfunctional Orexin-Regulated Neural Circuits in Alzheimer's Disease1R03AG070454-01A1GOFORTH, PAULETTE B.UNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$156,000CDIN
2022Targeting Type I IFN signaling to promote recovery following brain trauma in aged animals1R03AG070532-01A1BARRETT, JAMES PAULUNIVERSITY OF MARYLAND BALTIMORE, MD$154,500ZRG1
2022Cognitive decline in aging and AD: neuroprotection by hypermyelination in FusOLcKO1R03AG072218-01A1CAMBI, FRANCAUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$154,146ZRG1
2022Oxylipins, aging and Alzheimer’s disease1R03AG075465-01LEE, KIN SING STEPHENMICHIGAN STATE UNIVERSITY, MI$152,718CMAD
2022Deep brain stimulation of the Nucleus Basalis of Meynert: the role of stimulation parameters in neurogenesis and cognitive recovery1R03AG075637-01KUMBHARE, DEEPAKVIRGINIA COMMONWEALTH UNIVERSITY, VA$1CNNT
2021Contribution of peripheral immune dysregulation to Alzheimer's disease1R03AG070506-01WANG, JUNICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY$338,416CDIN
2021Cerebral vascular calcium signaling in diabetic Alzheimer's disease-related dementias1R03AG070784-01WANG, YONG-XIAOALBANY MEDICAL COLLEGE, NY$326,000BINP
2021Enduring effects of high estrogen on Alzheimer's disease1R03AG070687-01SUN, ZHENGBAYLOR COLLEGE OF MEDICINE, TX$320,000ZRG1
2021The impact of reduced blood flow early in Alzheimer's disease on neuronal function.1R03AG070507-01O'HERRON, PHILIPAUGUSTA UNIVERSITY, GA$308,000CDIN
2021Toxicity mechanisms of Aβ42 and Tau in aged cells1R03AG070478-01A1ZHOU, CHUANKAIBUCK INSTITUTE FOR RESEARCH ON AGING, CA$194,000CMAD
2021Impact of apolipoprotein E isoforms on brain lipoproteins1R03AG070480-01MELCHIOR, JOHNBATTELLE PACIFIC NORTHWEST LABORATORIES, WA$192,621CDIN
2021Second Generation Gene Therapy for APOE4 Homozygous Individuals at High Risk for Alzheimer's Disease1R03AG070738-01STILES, KATIE MWEILL MEDICAL COLL OF CORNELL UNIV, NY$169,500CMND
2021Exploring autophagy as a target for Alzheimer's Disease1R03AG072020-01LAZARUS, MICHAEL BLOCKICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY$169,375CMND
2021TYROBP/DAP12: a hub protein linking Alzheimer's disease, microglia, and gut microbiome.1R03AG070710-01A1HAURE-MIRANDE, JEAN-VIANNEYICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY$169,209CMBG
2021Understanding Social Communication Abilities in Individuals with Alzheimer's Disease1R03AG072236-01PAEK, EUN JINYOON, SI ONUNIVERSITY OF TENNESSEE HEALTH SCI CTR, TN$166,229LCOM
2021Use of super-resolution microscopy to visualize the interaction between Alzheimer therapeutic antibodies and Aβ aggregates1R03AG070709-01AMIN, LADANBOSTON UNIVERSITY MEDICAL CAMPUS, MA$165,000BPNS
2021Targeting P21-Highly-Expressing Senescent Cells In Vivo for Improving Cognitive Function in the Alzheimers Diseases1R03AG072374-01XU, MINGUNIVERSITY OF CONNECTICUT SCH OF MED/DNT, CT$164,000CDIN
2021The effects of APOE4 on carnitine/acylcarnitine mediated bioenergetic deficits in Alzheimer's disease1R03AG070540-01ABDULLAH, LAILAROSKAMP INSTITUTE, INC., FL$162,000NOMD
2021Influence of APOE genotype on cerebrovascular cell pathobiology in AD, and the contribution of microglia inflammation1R03AG073829-01OJO, JOSEPH OROSKAMP INSTITUTE, INC., FL$161,991CMBG
2021The brain cholesterol interactome1R03AG070428-01FERRIS, HEATHERUNIVERSITY OF VIRGINIA, VA$161,500CMBG
2021Hematopoietic Stem Cell Transplantation Combined with CSF1 Inhibition to Attenuate the Pathogenesis of Alzheimer's Disease1R03AG070421-01SUNG, ANTHONYDUKE UNIVERSITY, NC$161,000CDIN
2021Continuing Tool Development for Longitudinal Network Analysis: Enriching the Diagnostic Power of Disease-Specific Connectomic Biomarkers by Deep Graph Learning1R03AG070701-01WU, GUORONGUNIV OF NORTH CAROLINA CHAPEL HILL, NC$158,733EITN
2021Toward precision medicine: modulation of ABCA7 associated risk of Alzheimer's disease by ancestry1R03AG070512-01LYSSENKO, NICHOLASTEMPLE UNIV OF THE COMMONWEALTH, PA$158,500ZRG1
2021Impact of APOE Christchurch mutation on amyloid burden and tau pathology1R03AG073879-01MOON, YOUNGHYEINDIANA UNIVERSITY INDIANAPOLIS, IN$158,500ZRG1
2021Developing a screening platform to identify inhibitors of pathological self-assembly of Tau1R03AG070510-01BANERJEE, PRIYA R.STATE UNIVERSITY OF NEW YORK AT BUFFALO, NY$157,747BPNS
2021Imaging the metabolic and phagocytic landscape of microglia in Alzheimer’s disease1R03AG071791-01HEILSHORN, SARAH CSTANFORD UNIVERSITY, CA$157,525CMBG
2021Define molecular events driving selective neuronal death in multiple neurodegenerative diseases by snRNA-seq1R03AG070474-01XU, JINBINZHAO, GUOYANWASHINGTON UNIVERSITY, MO$157,500CDIN
2021The Mechanical Properties of the Brain and Their Effect on Alzheimer's Disease1R03AG073834-01GU, LUOJOHNS HOPKINS UNIVERSITY, MD$156,481BNVT
2021A novel experimental model of chronic stress and hypertension for studying dementia-related neurovascular dysfunction in the hippocampus1R03AG072016-01ERDOS, BENEDEKUNIVERSITY OF VERMONT & ST AGRIC COLLEGE, VT$156,000ZRG1
2021Prevalence and impact of cerebral anatomical variations: a risk factor for cognitive decline?1R03AG070469-01BARNES, JILL NICOLEUNIVERSITY OF WISCONSIN-MADISON, WI$155,000CNN
2021Development of isogenic iPSC cell lines expressing tauopathy-related PERK risk variants to study homeostatic control of protein levels during ER stress1R03AG070415-01YUAN, SHAUNA HUNIVERSITY OF MINNESOTA, MN$154,751NOMD
2021Role of aging-dependent changes in neuronal sub-types in development of radiotherapy-induced cognitive decline in the elderly population1R03AG070586-01A1SABIRZHANOV, BORISSTOICA, BOGDAN ADRIANUNIVERSITY OF MARYLAND BALTIMORE, MD$154,500CDIN
2021Role of age-dependent repetitive element transcript dysregulation in Alzheimers disease1R03AG070562-01A1LAROCCA, THOMASCOLORADO STATE UNIVERSITY, CO$152,000CMND
2021Recovery of Synaptic Dysfunction and Memory Loss in Alzheimer's Disease by Selective Co-Activation of Nicotinic Acetylcholine Receptors1R03AG072102-01A1KIM, SEONILCOLORADO STATE UNIVERSITY, CO$152,000NCF
2021Super-Resolution Tau PET Imaging for Alzheimer's Disease1R03AG070750-01DUTTA, JOYITAUNIVERSITY OF MASSACHUSETTS LOWELL, MA$151,980CNN
2021Effects of cell-type specific brain stimulation in Alzheimer's model mice1R03AG070517-01SATO, TAKASHIMEDICAL UNIVERSITY OF SOUTH CAROLINA, SC$150,500CDIN
2021Investigation of the role of glia cells in Alzheimers pathogenesis in a functional human-based in vitro model1R03AG070514-01GUO, XIUFANGUNIVERSITY OF CENTRAL FLORIDA, FL$148,185BNVT
2021Characterizing upstream regulators of glucosylceramide metabolism for Parkinson's disease and Lewy Body Dementia1R03AG070492-01NORTH, BRIAN J.CREIGHTON UNIVERSITY, NE$145,500CMND
2021Deciphering the effect of human microbiota on Alzheimer's disease using C. elegans models of protein conformational diseases1R03AG070580-01CZYZ, DANIEL MILOSZUNIVERSITY OF FLORIDA, FL$76,250CMND
2021Understanding the link between FAIM expression and Alzheimer’s disease and related dementias1R03AG072148-01KAKU, HIROAKIWESTERN MICHIGAN UNIV SCHOOL OF MEDICINE, MI$75,500CMND
2021Contribution of Endothelial Changes and Increased Cardiovascular Risk to Alzheimer's Disease Pathogenesis1R03AG070541-01A1CLEUREN, AUDREYUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$1ZRG1

Data: Grants.gov's daily extract and NIH's notice pages and award files, in ScienceGraph release conductgrants-2026-11-09-0.1.0. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.

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PAS-19-392: Small Research Grant Program for the Next Generation of Researchers in AD/ADRD Research: Area of Focus Basic Science (R03 Clinical Trials Not Allowed) | ScienceDex | ConductScience