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NIH funding notice RFA-AG-14-002

Optogenetic Tools for the Study of Neural Systems in Aging and Alzheimer's Disease (R01)

Closed on August 1, 2013.

Posted
April 17, 2013
Close date
August 1, 2013
Activity codes
Not stated on the notice page
Institutes taking part
Not stated on the notice page

The notices it replaced

Its page was not saved, so the notices it replaced are not known.

Who won it before

Competing awards, new and renewals, since FY2014, under this notice and the notices it replaced.

Past awards
8
8 new
Median first-year cost
$1,720,815
$10,670,087 in all
Institutions
7
8 contact PIs
Patents
21
from 3 funded projects

Awards by fiscal year

Fiscal years 2014 to 2026.

Most frequent institutions

  1. STANFORD UNIVERSITY2
  2. CALIFORNIA INSTITUTE OF TECHNOLOGY1
  3. EMORY UNIVERSITY1
  4. J. DAVID GLADSTONE INSTITUTES1
  5. MASSACHUSETTS INSTITUTE OF TECHNOLOGY1

and 2 other institutions

Most frequent study sections

  1. Special Emphasis Panel (ZAG1 ZIJ-5 (J3))8
8 awards under RFA-AG-14-002 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
FY2014Optogenetic dissection of brain network deficits in Alzheimer's Disease1RF1AG047669-01Jin, XinLee, Kuo-FenSALK INSTITUTE FOR BIOLOGICAL STUDIES, CAFirst-year cost $2,182,500Study section ZAG1
FY2014Optogenetic Study of ApoE4-Related Alzheimers Disease1RF1AG047655-01Huang, YadongKreitzer, AnatolJ. DAVID GLADSTONE INSTITUTES, CAFirst-year cost $2,148,750Study section ZAG1
FY2014Direct Visualization of Cell-Type Specific AD Networks for Drug Development1RF1AG047666-01Lee, Jin HyungSTANFORD UNIVERSITY, CAFirst-year cost $1,827,632Study section ZAG1
FY2014Consequences of Locus Coeruleus Activation in a Rat Model of Alzheimer's Disease1RF1AG047667-01Weinshenker, DavidEMORY UNIVERSITY, GAFirst-year cost $1,747,125Study section ZAG1
FY2014Examination of neural circuits underlying mood disorders in Alzheimer?s disease1RF1AG047661-01Tsai, Li-HueiTye, Kay MaxineMASSACHUSETTS INSTITUTE OF TECHNOLOGY, MAFirst-year cost $1,694,505Study section ZAG1
FY2014Intact Circuit Assessment of Aging Dopamine Neurons vis Optogenetics and CLARITY1R01AG047664-01Gradinaru, VivianaCALIFORNIA INSTITUTE OF TECHNOLOGY, CAFirst-year cost $374,625Study section ZAG1
FY2014Optogenetic interrogation of sleep circuits during aging1R01AG047671-01De Lecea, LuisWyss-Coray, TonySTANFORD UNIVERSITY, CAFirst-year cost $367,575Study section ZAG1
FY2014Optogenetic approaches to study complex neuronal circuits during cognitive aging1R01AG047652-01Griffith, William HTEXAS A&M UNIVERSITY HEALTH SCIENCE CTR, TXFirst-year cost $327,375Study section ZAG1
Newest fiscal year first, then first-year cost.

Patents from its funded projects

21 patents name 3 of the 8 funded projects. The newest 5, by patent number.

  1. US 12,653,904 (opens the patent at USPTO, a PDF, in a new tab)TARGETING PEPTIDES FOR DIRECTING ADENO-ASSOCIATED VIRUSES (AAVs)Granted June 16, 2026 to California Institute of TechnologyR01AG047664 · CALIFORNIA INSTITUTE OF TECHNOLOGY, CA
  2. US 12,544,588 (opens the patent at USPTO, a PDF, in a new tab)PREDICTING SUCCESSFUL GENERATION AND INHIBITION OF SEIZURE-LIKE AFTERDISCHARGES AND MAPPING THEIR SEIZURE NETWORKS USING FMRIGranted February 10, 2026 to The Board of Trustees of the Leland Stanford Junior UniversityRF1AG047666 · STANFORD UNIVERSITY, CA
  3. US 12,318,549 (opens the patent at USPTO, a PDF, in a new tab)METHODS AND DEVICES FOR PROVIDING A STIMULUS TO A SUBJECT TO INDUCE GAMMA OSCILLATIONSGranted June 3, 2025 to MASSACHUSETTS INSTITUTE OF TECHNOLOGYRF1AG047661 · MASSACHUSETTS INSTITUTE OF TECHNOLOGY, MA
  4. US 12,311,194 (opens the patent at USPTO, a PDF, in a new tab)SYSTEMS AND METHODS FOR PREVENTING, MITIGATING, AND/OR TREATING DEMENTIAGranted May 27, 2025 to MASSACHUSETTS INSTITUTE OF TECHNOLOGYRF1AG047661 · MASSACHUSETTS INSTITUTE OF TECHNOLOGY, MA
  5. US 12,296,106 (opens the patent at USPTO, a PDF, in a new tab)METHODS AND DEVICES FOR PROVIDING A STIMULUS TO A SUBJECT TO INDUCE GAMMA OSCILLATIONSGranted May 13, 2025 to MASSACHUSETTS INSTITUTE OF TECHNOLOGYRF1AG047661 · MASSACHUSETTS INSTITUTE OF TECHNOLOGY, MA

Each number opens the patent at USPTO, beside the project NIH ties it to and that project's institution. NIH ties a patent to a project, not to a year of its funding, and says its list is incomplete. The grant date and the owners are USPTO's: the organizations the patent names as assignees on the day it was granted. Source: United States Patent and Trademark Office, www.uspto.gov, which does not endorse ScienceDex.

Data: Grants.gov's daily extract and NIH's notice pages, award files and patents file, in ScienceGraph release conductgrants-2026-11-13-0.3.2. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.

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