Skip to main content
NIH funding notice RFA-AG-18-022

Understanding the Effects of ApoE2 on the Interaction between Aging and Alzheimers Disease (R01 - Clinical Trial Not Allowed)

Closed on March 28, 2018.

Posted
December 21, 2017
Close date
March 28, 2018
Activity codes
Not stated on the notice page
Institutes taking part
Not stated on the notice page

The notices it replaced

Its page was not saved, so the notices it replaced are not known.

Who won it before

Competing awards, new and renewals, since FY2014, under this notice and the notices it replaced.

Past awards
8
8 new
Median first-year cost
$708,092
$10,374,594 in all
Institutions
8
8 contact PIs
Patents
1
from 1 funded project

Awards by fiscal year

Fiscal years 2014 to 2026.

Most frequent institutions

  1. BECKMAN RESEARCH INSTITUTE/CITY OF HOPE1
  2. BOSTON UNIVERSITY MEDICAL CAMPUS1
  3. BUCK INSTITUTE FOR RESEARCH ON AGING1
  4. DUKE UNIVERSITY1
  5. SCRIPPS RESEARCH INSTITUTE, THE1

and 3 other institutions

Most frequent study sections

  1. Special Emphasis Panel (ZAG1 ZIJ-U (A2))7
  2. ZAG1-ZIJ-U(A2)1
8 awards under RFA-AG-18-022 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
FY2018Identification of a missing key element underlying apoE2 neuroprotection in Alzheimer's disease and the aging brain1RF1AG061872-01Han, XianlinSeshadri, SudhaUNIVERSITY OF TEXAS HLTH SCIENCE CENTER, TXFirst-year cost $3,382,940Study section ZAG1
FY2018ApoE2 in Alzheimer's disease: the neuroprotective effects and mechanisms1RF1AG061794-01Shi, YanhongBECKMAN RESEARCH INSTITUTE/CITY OF HOPE, CAFirst-year cost $3,134,935Study section ZAG1
FY2018Resilience pathways modeling human longevity-promoting ApoE variants in induced pluripotent stem cells1R01AG061879-01Ellerby, Lisa MMelov, SimonBUCK INSTITUTE FOR RESEARCH ON AGING, CAFirst-year cost $879,592Study section ZAG1
FY2018ApoE2 and protective molecular signatures in Alzheimer's disease and aging1R01AG061853-01Kulminski, Alexander MDUKE UNIVERSITY, NCFirst-year cost $781,190Study section ZAG1
FY2018APOE Orchestrated Molecular Signatures in Aging Brain and AD-the Contribution of APOE21R01AG057565-01A1Koldamova, RadosvetaLefterov, IliyaUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PAFirst-year cost $634,993Study section ZAG1
FY2018Sleep and ApoE2 Interactions in Alzheimer Disease1R56AG061867-01Veasey, Sigrid CUNIVERSITY OF PENNSYLVANIA, PAFirst-year cost $594,698Study section ZAG1
FY2018Neuroprotective Mechanisms of S-Nitrosylated ApoE2 in Aging and Alzheimer's Disease1R01AG061845-01Nakamura, TomohiroSCRIPPS RESEARCH INSTITUTE, THE, CAFirst-year cost $483,750Study section ZAG1
FY2018Protein Signatures of APOE2 and Cognitive Aging1R01AG061844-01Perls, Thomas TSebastiani, PaolaBOSTON UNIVERSITY MEDICAL CAMPUS, MAFirst-year cost $482,496Study section ZAG1
Newest fiscal year first, then first-year cost.

Patents from its funded projects

1 patent names 1 of the 8 funded projects.

  1. US 12,502,562 (opens the patent at USPTO, a PDF, in a new tab)HUMAN iPSC-DERIVED BRAIN ORGANOIDS AND USES THEREOFGranted December 23, 2025 to CITY OF HOPERF1AG061794 · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE, CA

Each number opens the patent at USPTO, beside the project NIH ties it to and that project's institution. NIH ties a patent to a project, not to a year of its funding, and says its list is incomplete. The grant date and the owners are USPTO's: the organizations the patent names as assignees on the day it was granted. Source: United States Patent and Trademark Office, www.uspto.gov, which does not endorse ScienceDex.

Data: Grants.gov's daily extract and NIH's notice pages, award files and patents file, in ScienceGraph release conductgrants-2026-11-15-0.3.4. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.

ScienceDex for departments

Open NIH notices that fit your faculty

See which open NIH funding notices fit each faculty member's CV, why each fits, and who won before.