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NIH funding notice RFA-AI-20-076

New Technologies for the In vivo Delivery of Gene Therapeutics for an HIV Cure (R01 Clinical Trial Not Allowed)

Closed on March 17, 2023.

Posted
October 20, 2020
Close date
March 17, 2023
Activity codes
Not stated on the notice page
Institutes taking part
Not stated on the notice page

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

Its page was not saved, so the notices it replaced are not known.

Who won it before

13 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $9,841,859 in first-year total cost, median $769,737.

Most frequent study sections

  1. Special Emphasis Panel[ZAI1 BJM-A (S1)]5
  2. Special Emphasis Panel[ZAI1 KSW-A (S1)]4
  3. Special Emphasis Panel[ZAI1 LK-A (S2)]4

Most frequent institutions

  1. ALBERT EINSTEIN COLLEGE OF MEDICINE1
  2. BOSTON CHILDREN'S HOSPITAL1
  3. FLORIDA INTERNATIONAL UNIVERSITY1
  4. FRED HUTCHINSON CANCER CENTER1
  5. FRED HUTCHINSON CANCER RESEARCH CENTER1
Competing awards under RFA-AI-20-076 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2024Vectored HIV Immunotherapy via in vivo B cell editing1R01AI174270-01A1CURIEL, DAVID TERRYFARZAN, MICHAEL R.MARTINS, MAURICIO DE AGUIARWASHINGTON UNIVERSITY, MO$1,289,517ZAI1
2024Eliminating the Immunogenicity of AAV Vectored HIV Antibody Delivery1R01AI174276-01A1BALAZS, ALEJANDRO BENJAMINMASSACHUSETTS GENERAL HOSPITAL, MA$822,056ZAI1
2024Capsid-engineered AAV vectors with Brec1-based gene therapeutics for inactivating the HIV reservoir1R01AI181053-01KUMAR, PRITILANGE, ULRIKE C.YALE UNIVERSITY, CT$769,737ZAI1
2024Developing and evaluating cell-specific lentivectors capable of selective in vivo generation of anti-HIV T cells to cure HIV1R01AI174275-01A1GOLDSTEIN, HARRISALBERT EINSTEIN COLLEGE OF MEDICINE, NY$734,317ZAI1
2024A CRISP(e)R way to silence HIV1R01AI174269-01A1UNWALLA, HOSHANG JEHANGIRFLORIDA INTERNATIONAL UNIVERSITY, FL$365,159ZAI1
2023Lentivirus-like particle specific delivery of Cas12 ribonucleoprotein (RNP) to HIV reservoir cells in vivo for an HIV cure1R01AI174301-01HU, WENHUILI, QINGSHENGTEMPLE UNIV OF THE COMMONWEALTH, PA$915,099ZAI1
2023In vivo transformation of chimeric antigen receptor B cells for a functional cure of HIV1R01AI174277-01CHOE, HYERYUNFARZAN, MICHAEL R.BOSTON CHILDREN'S HOSPITAL, MA$790,719ZAI1
2023Eliminating the latent reservoir by targeted in vivo delivery of HIV-specific CARs1R01AI167061-01A1PARHIZ, HAMIDEHRILEY, JAMES L.UNIVERSITY OF PENNSYLVANIA, PA$689,181ZAI1
2023In vivo HSC gene therapy using a multi-modular HDAd vector for HIV cure1R01AI174304-01KIEM, HANS-PETERLIEBER, ANDRE MICHAELUNIVERSITY OF WASHINGTON, WA$685,904ZAI1
2022Evolving Novel AAV Vectors for Gene Therapy to Cure HIV1R01AI166969-01ASOKAN, ARAVINDSACHA, JONAH B.OREGON HEALTH & SCIENCE UNIVERSITY, OR$985,350ZAI1
2022In vivo CRISPR engineering of B cells to produce anti-HIV broadly neutralizing antibodies using novel nanoparticles1R01AI167009-01ADAIR, JENNIFER EILEENTAYLOR, JUSTIN JFRED HUTCHINSON CANCER CENTER, WA$877,927ZAI1
2022In vivo engineering of B cells for the secretion of HIV broadly neutralizing antibodies1R01AI167003-01BARZEL, ADICANNON, PAULA MVOSS, JAMES EVENSCRIPPS RESEARCH INSTITUTE, THE, CA$645,746ZAI1
2022In Vivo Gene Editing of B cells with NICE-AAV Vectors1R01AI167004-01PETERSON, CHRISTOPHER WFRED HUTCHINSON CANCER RESEARCH CENTER, WA$271,147ZAI1

Data: Grants.gov's daily extract and NIH's notice pages and award files, in ScienceGraph release conductgrants-2026-11-09-0.1.0. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.

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