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NIH funding notice RFA-CA-15-009

Research Answers to NCI's Provocative Questions (R21)

Closed on October 28, 2016.

Posted
March 27, 2015
Close date
October 28, 2016
Activity codes
Not stated on the notice page
Institutes taking part
Not stated on the notice page

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

Its page was not saved, so the notices it replaced are not known.

Who won it before

29 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $5,683,463 in first-year total cost, median $198,578.

Most frequent study sections

  1. Special Emphasis Panel[ZCA1 RPRB-F (M1)]2
  2. Special Emphasis Panel[ZCA1 RPRB-M (M1)]2
  3. Special Emphasis Panel[ZCA1 RPRB-M (M2)]2
  4. Special Emphasis Panel[ZCA1 RPRB-M (M5)]2
  5. Special Emphasis Panel[ZCA1 RTRB-F (J2)]2

Most frequent institutions

  1. UNIVERSITY OF TX MD ANDERSON CAN CTR3
  2. INDIANA UNIVERSITY INDIANAPOLIS2
  3. UNIVERSITY OF MICHIGAN AT ANN ARBOR2
  4. BAYLOR COLLEGE OF MEDICINE1
  5. BRIGHAM AND WOMEN'S HOSPITAL1
Competing awards under RFA-CA-15-009 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2017Sequence variation in mtDNA and extreme survival in glioblastoma1R21CA216227-01EGAN, KATHLEEN M.WILLIAMS, SION LLEWELYNH. LEE MOFFITT CANCER CTR & RES INST, FL$249,944ZCA1
2017(PQ 5) Roles of mitochondrial heterogeneity in cell survival and oncogenesis1R21CA216304-01NEWMEYER, DONALD DAVIDLA JOLLA INSTITUTE FOR IMMUNOLOGY, CA$234,900ZCA1
2017Uncovering Gene Expression Differences between Benign and Premalignant Colorectal Polyps1R21CA208461-01A1VILAR SANCHEZ, EDUARDOUNIVERSITY OF TX MD ANDERSON CAN CTR, TX$219,902ZCA1
2017(PQ1) Cellular senescence as an initiating event in malignant transformation1R21CA206013-01A1DAVID, GREGORYNEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY$203,400ZCA1
2017Investigating developmental Hox programs as determinants of sarcomagenesis1R21CA215968-01LAWLOR, ELIZABETH RWELLIK, DENEEN MUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$202,275ZCA1
2017(PQ#9): Altered mitochondrial transport and chemotherapy-induced peripheral neuropathy1R21CA215985-01CHANG, KAREN TUNIVERSITY OF SOUTHERN CALIFORNIA, CA$198,000ZCA1
2017Determining the Influence Genomic Instability During Embryogenesis has on Tumor Penetrance1R21CA219546-01PARANT, JOHN MUNIVERSITY OF ALABAMA AT BIRMINGHAM, AL$193,793ZCA1
2017(PQ7) A multi-fluorescent intravital microscopy approach to study osteosarcoma1R21CA208618-01A1INTINI, GIUSEPPEHARVARD MEDICAL SCHOOL, MA$191,221ZCA1
2017Telomere-related Genomic Instability in Early Colorectal Carcinogenesis1R21CA205434-01A1TANAKA, HIROMIINDIANA UNIVERSITY INDIANAPOLIS, IN$187,200ZCA1
2017PQ-10: Microbial metabolite, Urolithin A is a potent immunomodulator and chemosensitizing adjuvant in treating colon cancer.1R21CA216090-01JALA, VENKATAKRISHNA RAOUNIVERSITY OF LOUISVILLE, KY$167,475ZCA1
2017Impact of macrophage PCSK9 on breast cancer1R21CA216230-01FAN, DAPINGUNIVERSITY OF SOUTH CAROLINA AT COLUMBIA, SC$160,200ZCA1
2017(6) Molecular mechanisms explaining premalignant changes in the etiology of melanoma1R21CA208736-01A1MURPH, MANDI MUNIVERSITY OF GEORGIA, GA$146,000ZCA1
2016(PQ10) Do microbiota alter the epigenetic landscape in human genome1R21CA208464-01STRONGIN, ALEX YSANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE, CA$254,475ZCA1
2016(PQ9) Dual Action RSK Inhibitor: Targeting Metastasis and Providing Cardioprotection1R21CA208631-01LANNIGAN, DEBORAHVANDERBILT UNIVERSITY MEDICAL CENTER, TN$251,120ZCA1
2016(1) Intestinal Organoid Models for APC LOH1R21CA208638-01GIARDINA, CHARLES A.UNIVERSITY OF CONNECTICUT STORRS, CT$232,195ZCA1
2016Novel Mouse Models to define Genetic Drivers of Aggressive Prostate Cancer1R21CA205627-01ELLIS, LEIGHROSWELL PARK CANCER INSTITUTE CORP, NY$223,808ZCA1
2016(PQ4) Elucidating Determinants of Susceptibility to Tumorigenesis in the Skin1R21CA208298-01RAMSEY, MATTHEW ROBERTBRIGHAM AND WOMEN'S HOSPITAL, MA$217,016ZCA1
2016(PQ 6) Exploiting Frequent Alterations in the PRC2 Complex to Distinguish Benign Neurofibromas from Malignant Peripheral Nerve Sheath Tumors1R21CA208723-01BETTEGOWDA, CHETANJOHNS HOPKINS UNIVERSITY, MD$212,824ZCA1
2016(PQ4) Mutations in the histone chaperone DAXX drive pancreatic neuroendocrine tumors not ductal adenocarcinomas1R21CA208463-01LOZANO, GUILLERMINAUNIVERSITY OF TX MD ANDERSON CAN CTR, TX$208,800ZCA1
2016The Role of Mitochondrial Heterogeneity in Pyruvate Flux in Prostate Cancer Progression1R21CA205257-01MCGUIRE, SEAN EBAYLOR COLLEGE OF MEDICINE, TX$206,843ZCA1
2016Unlocking Tumor Immunophenotype in Responders versus Non-Responders in Metastatic Uveal Melanoma Patients Receiving Immune Checkpoint Blockade1R21CA208609-01PATEL, SAPNAUNIVERSITY OF TX MD ANDERSON CAN CTR, TX$203,580ZCA1
2016(PQ3) Modulation of Osteosarcoma Biology by Inflammation and Immunity Defined through a ComparativeApproach1R21CA208529-01MODIANO, JAIME F.UNIVERSITY OF MINNESOTA, MN$198,578ZCA1
2016(PQ9) Prevention of Bleomycin-induced Pulmonary Toxicity by Dichloroacetate (DCA)1R21CA208746-01KIM, JUNG-WHANUNIVERSITY OF TEXAS DALLAS, TX$198,485ZCA1
2016Pax2 loss in fallopian tube lesions and strategies for restoration in serous cancer1R21CA208610-01BURDETTE, JOANNA EUNIVERSITY OF ILLINOIS AT CHICAGO, IL$196,475ZCA1
2016PQ3: Age-related immune deviation and cancer outcome1R21CA205430-01KUMMAR, SHIVAANIMAECKER, HOLDEN T.STANFORD UNIVERSITY, CA$171,825ZCA1
2016(10.) The Gut Microbiome and Responses to Neoadjuvant Chemoradiation in Rectal Cancer Patients1R21CA205636-01CHEN, GRACE Y.UNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$168,563ZCA1
2016(PQ11) Reversing exosome-mediated immune suppression - a novel strategy for cancer therapy1R21CA205644-01BOYIADZIS, MICHAELWHITESIDE, THERESA L.UNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$167,475ZCA1
2016"(PQ8) BONE MARROW-ON-A-CHIP":AN INVITRO 3D MODEL OF BREAST CANCER DORMANCY1R21CA208519-01GEORGE, STEVEN CARLWASHINGTON UNIVERSITY, MO$165,844ZCA1
2016(PQ9) Novel therapeutic approaches to chemotherapy-induced muscle.1R21CA205437-01WANING, DAVID LINDIANA UNIVERSITY INDIANAPOLIS, IN$51,247ZCA1

Data: Grants.gov's daily extract and NIH's notice pages and award files, in ScienceGraph release conductgrants-2026-11-10-0.1.1. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.

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