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NIH funding notice RFA-CA-17-017

Research Answers to NCI's Provocative Questions (R01)

Closed on January 23, 2018.

Posted
March 3, 2017
Close date
January 23, 2018
Activity codes
Not stated on the notice page
Institutes taking part
Not stated on the notice page

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

Its page was not saved, so the notices it replaced are not known.

Who won it before

31 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $14,522,358 in first-year total cost, median $444,969.

Most frequent study sections

  1. Special Emphasis Panel[ZCA1 SRB-A (J1)]8
  2. Special Emphasis Panel[ZCA1 SRB-K (M2)]8
  3. Special Emphasis Panel[ZCA1 SRB-A (M1)]5
  4. Special Emphasis Panel[ZCA1 SRB-K (J1)]4
  5. Special Emphasis Panel[ZCA1 SRB-5 (J2)]3

Most frequent institutions

  1. DANA-FARBER CANCER INST3
  2. NEW YORK UNIVERSITY SCHOOL OF MEDICINE2
  3. THOMAS JEFFERSON UNIVERSITY2
  4. UNIVERSITY OF TX MD ANDERSON CAN CTR2
  5. YALE UNIVERSITY2
Competing awards under RFA-CA-17-017 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2018(8) Genetics of Immune Related Adverse Events and Response to Immunotherapy1R01CA227466-01ZIV, ELADUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$699,062ZCA1
2018(PQ3) A functional genomic approach to identification and interpretation of germline-tumor genetic interactions1R01CA227237-01GUSEV, ALEXANDERZAITLEN, NOAH ADANA-FARBER CANCER INST, MA$686,519ZCA1
2018(PQ5) Mitochondrial Heterogeneity in Melanoma Tumor and Immune Responses1R01CA216101-01A1KAECH, SUSAN MSHADEL, GERALDSALK INSTITUTE FOR BIOLOGICAL STUDIES, CA$670,933ZCA1
2018(PQ3) UNDERSTANDING THE INTERACTIONS BETWEEN GERMLINE AND SOMATIC ALTERATIONS in the PATHOGENESIS OF GLIOMAS1R01CA230712-01JENKINS, ROBERT B.MAYO CLINIC ROCHESTER, MN$633,992ZCA1
2018(8) Genomic determinants of the T-cell regulome in immune checkpoint blockade1R01CA227505-01KIRCHHOFF, TOMASWEBER, JEFFREY SNEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY$620,860ZCA1
2018(PQ2) PD-L1/PD-1 signals in aged hosts undergoing cancer immunotherapy1R01CA231325-01CURIEL, TYLER J.SHEN-ORR, SHAI SHLOMOUNIVERSITY OF TEXAS HLTH SCIENCE CENTER, TX$582,917ZCA1
2018(8) Mechanisms of autoimmune endocrine diseases in patients receiving checkpoint inhibitors1R01CA227473-01HEROLD, KEVAN CKLUGER, HARRIET M.YALE UNIVERSITY, CT$580,767ZCA1
2018(PQ4) Novel tools for in vivo study of genetic interactions in cancer progression1R01CA231112-01CHEN, SIDIYALE UNIVERSITY, CT$576,627ZCA1
2018(PQ5) Contribution of mitochondrial pathways to metabolic heterogeneity in molecular subtypes of Diffuse Large B Cell Lymphoma1R01CA219850-01A1DANIAL, NIKA NMARTO, JARROD A.DANA-FARBER CANCER INST, MA$558,022ZCA1
2018(PQ #8) Biomarkers of efficacy and adverse events due to treatment with immune checkpoint inhibitors1R01CA231291-01ATKINS, MICHAEL BENJAMINWELLSTEIN, ANTONGEORGETOWN UNIVERSITY, DC$533,211ZCA1
2018(PQ1) Adaptive immune and microbial mechanisms regulating Lynch syndrome penetrance1R01CA231283-01LIPKIN, STEVEN MWEILL MEDICAL COLL OF CORNELL UNIV, NY$501,220ZCA1
2018(PQ8) Predicting immune-related toxicity in the adjuvant melanoma setting with checkpoint inhibition1R01CA231295-01OSMAN, IMANWEBER, JEFFREY SNEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY$481,288ZCA1
2018(PQ4) Quantitative and multiplexed analysis of gene function in cancer in vivo1R01CA231253-01PETROV, DMITRIWINSLOW, MONTE MEIERSTANFORD UNIVERSITY, CA$471,700ZCA1
2018(PQ12) Enhancement of DNA repair in neurons via a targeted APE1 small molecule modifier to decrease and reverse chemotherapy-induced peripheral neuropathy (CIPN)1R01CA231267-01FEHRENBACHER, JILL CKELLEY, MARK R.INDIANA UNIVERSITY INDIANAPOLIS, IN$460,814ZCA1
2018(PQ10) The impact of the gut microbiome on the anti-tumor effects of radiotherapy1R01CA219871-01A1FACCIABENE, ANDREAKOUMENIS, CONSTANTINOSUNIVERSITY OF PENNSYLVANIA, PA$451,326ZCA1
2018Role of GPR120 and Macrophages in Dietary Omega-3 Fatty Acid Inhibition of Prostate Cancer1R01CA231219-01ARONSON, WILLIAM JCOHEN, PINCHASUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$444,969ZCA1
2018(PQ6)Nuclear receptor mechanisms in circadian disruption induced hepatocarcinogenesis1R01CA230848-01FU, LONING NONEMOORE, DAVID DBAYLOR COLLEGE OF MEDICINE, TX$442,560ZCA1
2018(PQ10) Enhancing responses to immune checkpoint blockade in melanoma via modulation of the microbiome1R01CA219896-01A1WARGO, JENNIFER A.UNIVERSITY OF TX MD ANDERSON CAN CTR, TX$429,943ZCA1
2018(PQ 12) Targeting SMPDL3b to Prevent Radiation-Induced Nephrotoxicity1R01CA227493-01FORNONI, ALESSIAMARPLES, BRIANUNIVERSITY OF MIAMI SCHOOL OF MEDICINE, FL$427,990ZCA1
2018(PQ5) Relevance of VDAC2 heterogeneity for hepatic tumor growth and targeting1R01CA216254-01A1HAJNOCZKY, GYORGYTHOMAS JEFFERSON UNIVERSITY, PA$413,916ZCA1
2018Integrative Somatic and Germline Computational Biology to Redefine Clinical Actionability in Solid Tumors1R01CA227388-01VAN ALLEN, ELIEZER MDANA-FARBER CANCER INST, MA$407,175ZCA1
2018(PQ1) The role of cell-to-cell variation in the penetrance of heritable mutant RAS hypodermal neoplasias1R01CA219460-01A1MENDENHALL, ALEXANDER RICHARDUNIVERSITY OF WASHINGTON, WA$397,573ZCA1
2018TP53 Germline Mutations: Beyond LFS1R01CA219556-01A1LI, YONGCLEVELAND CLINIC LERNER COM-CWRU, OH$377,037ZCA1
2018(PQ4) - Tools for simultaneous disruption of multiple epigenetically silenced genes for studying their roles in tumorigenesis using ex vivo human and mouse colon organoid and in vivo mouse models1R01CA230995-01BAYLIN, STEPHEN B.EASWARAN, HARIHARANJOHNS HOPKINS UNIVERSITY, MD$374,578ZCA1
2018PQ12 Targeting HDAC6 for Chemotherapy-Induced Neuropathy and Chemobrain1R01CA227064-01HEIJNEN, COBI JKAVELAARS, ANNEMIEKEUNIVERSITY OF TX MD ANDERSON CAN CTR, TX$366,766ZCA1
2018Exosomes and platinum-induced peripheral neuropathy1R01CA219829-01A1ZHANG, ZHENG GANGHENRY FORD HEALTH SYSTEM, MI$358,545ZCA1
2018(11) Diet Modification to Augment Radiation for Breast Cancer Brain Metastases1R01CA227479-01SIMONE, NICOLE LTHOMAS JEFFERSON UNIVERSITY, PA$351,726ZCA1
2018PQ2 Obesity-induced fibrocytes promote breast cancer progression1R01CA227542-01ARENDT, LISA MUNIVERSITY OF WISCONSIN-MADISON, WI$349,988ZCA1
2018Genomic Prediction of Doxorubicin-Induced Cardiotoxicity1R01CA220002-01A1BURRIDGE, PAUL W.STRANGER, BARBARA ENORTHWESTERN UNIVERSITY AT CHICAGO, IL$339,052ZCA1
2018(PQ12) Peroxisome proliferator-activated receptor alpha agonists as potential treatment for chemotherapy-induced peripheral neuropathy1R01CA219637-01A1DAMAJ, M. IMADGEWIRTZ, DAVID A.VIRGINIA COMMONWEALTH UNIVERSITY, VA$281,441ZCA1
2018(PQ9) Developing EZH2 Degraders for Treating Triple-Negative Breast Cancer1R01CA230854-01JIN, JIANPARSONS, RAMON EICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY$249,841ZCA1

Data: Grants.gov's daily extract and NIH's notice pages and award files, in ScienceGraph release conductgrants-2026-11-11-0.1.2. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.

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