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NIH funding notice RFA-CA-22-022

Early-Stage Development of Informatics Technologies for Cancer Research and Management (U01 Clinical Trial Optional)

Closed on November 17, 2022.

Posted
March 24, 2022
Close date
November 17, 2022
Activity codes
U01
Institutes taking part
NCI

The notices it replaced

3 notices since 2019, oldest first, each with its awards since FY2014.

  1. Posted 2019RFA-CA-19-0395 awards
  2. Posted 2020RFA-CA-20-0086 awards
  3. Posted 2020RFA-CA-21-0146 awards
  4. Posted 2022RFA-CA-22-022This notice, closed · 6 awards

Replaced by RFA-CA-23-015.

Who won it before

Competing awards, new and renewals, since FY2014, under this notice and the notices it replaced.

Past awards
23
23 new
Median first-year cost
$402,077
$9,325,103 in all
Institutions
20
23 contact PIs
Patents
6
from 1 funded project

Awards by fiscal year

Fiscal years 2014 to 2026.

Most frequent institutions

  1. JOHNS HOPKINS UNIVERSITY3
  2. UNIVERSITY OF PENNSYLVANIA2
  3. AUBURN UNIVERSITY AT AUBURN1
  4. BOSTON UNIVERSITY MEDICAL CAMPUS1
  5. CASE WESTERN RESERVE UNIVERSITY1

and 15 other institutions

Most frequent study sections

  1. Special Emphasis Panel (ZCA1 TCRB-T (J1))5
  2. Special Emphasis Panel (ZCA1 RTRB-R (M3))4
  3. Special Emphasis Panel (ZCA1 SRB-X (J1))4
  4. Special Emphasis Panel (ZCA1 TCRB-5 (J2))3
  5. Special Emphasis Panel (ZCA1 TCRB-J (M2))3

and 2 other study sections

23 awards under RFA-CA-22-022 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
FY2023Visual Analytics for Exploration and Hypothesis Generation Using Highly MultiplexedSpatial Data of Tissues and Tumors1U01CA284207-01Pfister, HanspeterSantagata, SandroHARVARD MEDICAL SCHOOL, MAFirst-year cost $415,436Study section ZCA1
FY2023Robust privacy preserving distributed analysis platform for cancer research: addressing data bias and disparities1U01CA274576-01A1Jiang, XiaoqianLong, QiUNIVERSITY OF PENNSYLVANIA, PAFirst-year cost $411,901Study section ZCA1
FY2023m6A-suite: an informatics pipeline and resource for elucidating roles of m6A epitranscriptome in cancer1U01CA279618-01Huang, YufeiUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PAFirst-year cost $408,557Study section ZCA1
FY2023Matching genotypes with personalized therapies: Development of a decision support infrastructure to augment the value of precision medicine1U01CA274631-01A1Anagnostou, ValsamoBotsis, TaxiarchisJOHNS HOPKINS UNIVERSITY, MDFirst-year cost $407,738Study section ZCA1
FY2023Inferring Kinase Activity from Tumor Phosphoproteomic Data1U01CA284193-01Naegle, Kristen MUNIVERSITY OF VIRGINIA, VAFirst-year cost $404,886Study section ZCA1
FY2023Personalization of graphical models using multi-omics data for subtype discovery and prognosis1U01CA274573-01A1Luu, Hung NNguyen, Tin CAUBURN UNIVERSITY AT AUBURN, ALFirst-year cost $392,740Study section ZCA1
FY2022GEARBOx - a multisite clinical trial matching tool for children with relapsed or refractory cancer1U01CA269420-01 · under RFA-CA-21-014Volchenboum, SamuelUNIVERSITY OF CHICAGO, ILFirst-year cost $531,117Study section ZCA1
FY2022Analytical tools for studying the tumor microenvironment leveraging spatial transcriptomics1U01CA274489-01 · under RFA-CA-21-014Fridley, Brooke LH. LEE MOFFITT CANCER CTR & RES INST, FLFirst-year cost $415,728Study section ZCA1
FY2022muMS2: an open source R package for analyzing and integrating multi-omics datasets to improve early detection and understanding of colorectal cancer1U01CA264071-01A1 · under RFA-CA-21-014Balunas, Marcy JSchloss, Patrick DavidUNIVERSITY OF MICHIGAN AT ANN ARBOR, MIFirst-year cost $408,122Study section ZCA1
FY2022Developing informatics tools for optimized MRS for brain cancer research1U01CA269110-01 · under RFA-CA-21-014Marjanska, MalgorzataUNIVERSITY OF MINNESOTA, MNFirst-year cost $380,671Study section ZCA1
FY2022A data-driven bioinformatics platform for the design and analysis of multiplexed antibody-based cytometry experiments in cancer research1U01CA269409-01A1 · under RFA-CA-21-014Gonzalez Camara, PabloUNIVERSITY OF PENNSYLVANIA, PAFirst-year cost $359,378Study section ZCA1
FY2022Development of Small Area Interactive Risk Maps for Cancer Control Efforts1U01CA258400-01A1 · under RFA-CA-21-014Oleson, JacobUNIVERSITY OF IOWA, IAFirst-year cost $349,606Study section ZCA1
FY2021Advanced development of Lancet, an emerging tool for complex variant calling in cancer genomics1U01CA253405-01A1 · under RFA-CA-20-008Narzisi, GiuseppeNEW YORK GENOME CENTER, NYFirst-year cost $506,507Study section ZCA1
FY2021Informatics Tools To Analyze And Model Whole Slide Image Data At The Single Cell Level1U01CA249245-01A1 · under RFA-CA-20-008Xiao, GuanghuaUT SOUTHWESTERN MEDICAL CENTER, TXFirst-year cost $407,930Study section ZCA1
FY2021PROTEAN-CR: Proteomics Toolkit for Ensemble Analysis in Cancer Research1U01CA258512-01 · under RFA-CA-20-008Kavraki, Lydia E.Lizee, Gregory ARICE UNIVERSITY, TXFirst-year cost $402,077Study section ZCA1
FY2021Utilizing Bayesian modeling to improve mutational signature inference in large-scale datasets1U01CA253500-01A1 · under RFA-CA-20-008Campbell, Joshua DYajima, MasanaoBOSTON UNIVERSITY MEDICAL CAMPUS, MAFirst-year cost $401,917Study section ZCA1
FY2021An informatics bridge over the valley of death for cancer Phase I trials of drug-combination therapies1U01CA248240-01A1 · under RFA-CA-20-008Li, LangOHIO STATE UNIVERSITY, OHFirst-year cost $387,617Study section ZCA1
FY2021Integrative genomic and epigenomic analysis of cancer using long read sequencing1U01CA253481-01A1 · under RFA-CA-20-008Schatz, MichaelJOHNS HOPKINS UNIVERSITY, MDFirst-year cost $383,463Study section ZCA1
FY2020Single-cell and imaging data integration software to spatially resolve the tumor microenvironment1U01CA253403-01 · under RFA-CA-19-039Fertig, ElanaJOHNS HOPKINS UNIVERSITY, MDFirst-year cost $405,874Study section ZCA1
FY2020Informatics for Functional Integration of Heterogeneous Cancer Genome and Transcriptome Sequencing Data1U01CA247760-01 · under RFA-CA-19-039Chen, KenUNIVERSITY OF TX MD ANDERSON CAN CTR, TXFirst-year cost $398,399Study section ZCA1
FY2020Informatics tools for identification, prioritization and clinical application of neoantigens1U01CA248235-01 · under RFA-CA-19-039Griffith, MalachiWASHINGTON UNIVERSITY, MOFirst-year cost $391,732Study section ZCA1
FY2020RadxTools for assessing tumor treatment response on imaging1U01CA248226-01 · under RFA-CA-19-039Tiwari, PallaviViswanath, Satish EaswarCASE WESTERN RESERVE UNIVERSITY, OHFirst-year cost $383,017Study section ZCA1
FY2020Technology for efficient simulation of cancer cell transport1U01CA253511-01 · under RFA-CA-19-039Randles, Amanda EDUKE UNIVERSITY, NCFirst-year cost $370,690Study section ZCA1
Newest fiscal year first, then first-year cost.

Patents from its funded projects

6 patents name 1 of the 23 funded projects. The newest 5, by patent number.

  1. US 12,755,841 (opens the patent at USPTO, a PDF, in a new tab)MULTI-SITE CROSS-ORGAN CALIBRATED DEEP LEARNING (MUSCID) METHOD AND APPARATUSGranted October 6, 2026 to Case Western Reserve University, Emory University and 2 othersU01CA248226 · CASE WESTERN RESERVE UNIVERSITY, OH
  2. US 12,530,770 (opens the patent at USPTO, a PDF, in a new tab)DEEP-LEARNING-BASED HEPATIC FAT ASSESSMENTGranted January 20, 2026 to Case Western Reserve University, Emory University and University Hospitals Cleveland Medical CenterU01CA248226 · CASE WESTERN RESERVE UNIVERSITY, OH
  3. US 12,400,327 (opens the patent at USPTO, a PDF, in a new tab)HYBRID CONVOLUTIONAL WAVELET NETWORKS FOR PREDICTING TREATMENT RESPONSE VIA RADIOLOGICAL IMAGES OF BOWEL DISEASEGranted August 26, 2025 to Case Western Reserve UniversityU01CA248226 · CASE WESTERN RESERVE UNIVERSITY, OH
  4. US 12,159,403 (opens the patent at USPTO, a PDF, in a new tab)COMBINATION OF FEATURES FROM BIOPSIES AND SCANS TO PREDICT PROGNOSIS IN SCLCGranted December 3, 2024 to The United States Government as Represented by the Department of Veteran AffairsU01CA248226 · CASE WESTERN RESERVE UNIVERSITY, OH
  5. US 12,073,560 (opens the patent at USPTO, a PDF, in a new tab)COMPUTATIONAL FEATURES OF TUMOR-INFILTRATING LYMPHOCYTE (TIL) ARCHITECTUREGranted August 27, 2024 to University of Pittsburgh—Of the Commonwealth System of Higher EducationU01CA248226 · CASE WESTERN RESERVE UNIVERSITY, OH

Each number opens the patent at USPTO, beside the project NIH ties it to and that project's institution. NIH ties a patent to a project, not to a year of its funding, and says its list is incomplete. The grant date and the owners are USPTO's: the organizations the patent names as assignees on the day it was granted. Source: United States Patent and Trademark Office, www.uspto.gov, which does not endorse ScienceDex.

Data: Grants.gov's daily extract and NIH's notice pages, award files and patents file, in ScienceGraph release conductgrants-2026-11-12-0.3.1. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.

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