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NIH funding notice RFA-CA-22-028

Cancer Adoptive Cellular Therapy Network (Can-ACT) for Adult Cancers (UG3/UH3 Clinical Trial Required)

Closed on June 30, 2023.

Posted
August 24, 2022
Close date
June 30, 2023
Activity codes
Not stated on the notice page
Institutes taking part
Not stated on the notice page

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

Its page was not saved, so the notices it replaced are not known.

Who won it before

5 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $7,070,333 in first-year total cost, median $1,413,547.

Most frequent study sections

  1. Special Emphasis Panel[ZCA1 RTRB-Y (M1)]3
  2. Special Emphasis Panel[ZCA1 RTRB-U (J2)]2

Most frequent institutions

  1. UNIVERSITY OF PENNSYLVANIA2
  2. MASSACHUSETTS GENERAL HOSPITAL1
  3. SLOAN-KETTERING INST CAN RESEARCH1
  4. UNIVERSITY OF TX MD ANDERSON CAN CTR1
Competing awards under RFA-CA-22-028 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2024CD28-KITv CAR T cells with PD-1 dominant negative receptor1UG3CA290241-01ADUSUMILLI, PRASAD S.SLOAN-KETTERING INST CAN RESEARCH, NY$1,491,519ZCA1
2024Dual-targeted DOTA CAR T cells with image-guided monitoring for solid tumor treatment1UG3CA290451-01FARWELL, MICHAEL DAVIDPOWELL, DANIEL J.UNIVERSITY OF PENNSYLVANIA, PA$1,453,091ZCA1
2023CAR T cells targeting mesothelin and secreting bispecific antibodies targeting fibroblasts in pancreatic cancer1UG3CA283619-01MAUS, MARCELA VALDERRAMAMASSACHUSETTS GENERAL HOSPITAL, MA$1,413,547ZCA1
2023HORMAD-specific TGF-beta resistant memory T cells for treatment of patients with Gastro-esophageal Cancer1UG3CA283615-01MORELLI, MARIA PIARAI, KUNALYEE, CASSIANUNIVERSITY OF TX MD ANDERSON CAN CTR, TX$1,406,916ZCA1
2023Next generation T cell therapies for mutant KRAS solid tumors1UG3CA283652-01CARRENO, BEATRIZ M.JUNE, CARL H.LINETTE, GERALD PUNIVERSITY OF PENNSYLVANIA, PA$1,305,260ZCA1

Data: Grants.gov's daily extract and NIH's notice pages and award files, in ScienceGraph release conductgrants-2026-11-10-0.1.1. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.

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