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NIH funding notice RFA-CA-24-008

Innovative Molecular and Cellular Analysis Technologies for Basic and Clinical Cancer Research (R61 Clinical Trial Not Allowed)

Closed on October 1, 2024.

Posted
November 28, 2023
Close date
October 1, 2024
Activity codes
R61
Institutes taking part
NCI

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

  1. Reissues: RFA-CA-23-002 Innovative Molecular and Cellular Analysis Technologies for Basic and Clinical Cancer Research (R61 Clinical Trial Not Allowed)
  2. 2 steps back: RFA-CA-22-001 Innovative Molecular and Cellular Analysis Technologies for Basic and Clinical Cancer Research (R61 Clinical Trial Not Allowed)

Replaced by RFA-CA-25-001.

Who won it before

35 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $10,444,778 in first-year total cost, median $224,863.

Most frequent study sections

  1. Special Emphasis Panel[ZCA1 TCRB-D (O1)]8
  2. Special Emphasis Panel[ZCA1 TCRB-Q (J1)]8
  3. Special Emphasis Panel[ZCA1 TCRB-D (M2)]6
  4. Special Emphasis Panel[ZCA1 TCRB-Q (O1)]5
  5. Special Emphasis Panel[ZCA1 TCRB-5 (M1)]4

Most frequent institutions

  1. STANFORD UNIVERSITY3
  2. BROAD INSTITUTE, INC.2
  3. COLUMBIA UNIV NEW YORK MORNINGSIDE2
  4. ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI2
  5. UNIVERSITY OF PENNSYLVANIA2
Competing awards under RFA-CA-24-008 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2025Ultra-sensitive mass spectrometry-based immunopeptidomics using digital microfluidics.1R61CA297867-01A1CARON, ETIENNEYALE UNIVERSITY, CT$672,371ZCA1
2025High throughput multidimensional chemoproteomics for function-directed covalent target discovery1R61CA302550-01BACKUS, KERIANN MARIEUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$649,181ZCA1
2025"Charting cellular attraction-based interactome with Multivalent Adhesive Probe AFM (MAPA)"1R61CA291213-01A1GACZYNSKA, MARIA EOSMULSKI, PAWEL A.UNIVERSITY OF TEXAS HLTH SCIENCE CENTER, TX$635,749ZCA1
2025Development of Personalized Intact Proteome Map for Ovarian Cancer Patients Using Ultrasensitive Multiplexed Top-down Proteomics1R61CA297964-01A1BURGETT, ANTHONY W.G.WU, SIUNIVERSITY OF ALABAMA IN TUSCALOOSA, AL$631,621ZCA1
2025Defining Intercellular Heterogeneity in Cell Cycle Quiescence1R61CA302625-01COOK, JEANETTE GOWENUNIV OF NORTH CAROLINA CHAPEL HILL, NC$627,676ZCA1
2025High-throughput and multiplex single-molecule quantification and sorting of single EV1R61CA302620-01ISSADORE, DAVID AARONUNIVERSITY OF PENNSYLVANIA, PA$625,756ZCA1
2025High-throughput single-cell joint RNA and DNA methylation mapping of Acute Myeloid Leukemia1R61CA297881-01MA, SAIICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY$237,023ZCA1
2025Enriching and Base-Resolution Profiling of 5-Methylcytosine in Degraded Clinical Samples1R61CA297947-01TANG, WEIXINUNIVERSITY OF CHICAGO, IL$230,010ZCA1
2025Mapping Dynamic Changes in Protein Interactome using Proximity Labeling with High Temporal Resolution1R61CA297953-01ADIBEKIAN, ALEXANDERKARGINOV, ANDREI VUNIVERSITY OF ILLINOIS AT CHICAGO, IL$224,863ZCA1
2025An enabling approach for deep metaproteomic characterization ofmicrobial contributors to tumorigenesis in clinical samples1R61CA291168-01A1GRIFFIN, TIMOTHY J.HUNTER, RYAN COULSONJAGTAP, PRATIK DUNIVERSITY OF MINNESOTA, MN$221,456ZCA1
2025Red-light driven targeted degradation of cancer proteins1R61CA297882-01ROVIS, TOMISLAVSHAH, NEEL HCOLUMBIA UNIV NEW YORK MORNINGSIDE, NY$218,886ZCA1
2024Bioreactor for Manufacturing Chemotactically Competent Immune Cell Therapies1R61CA281785-01A1 · under RFA-CA-23-002LIU, XIAOHESRI INTERNATIONAL, CA$375,016ZCA1
2024New Chemical Tools for Covalent Drug Discovery1R61CA278449-01A1 · under RFA-CA-23-002KIM, JUSTINMARTO, JARROD A.DANA-FARBER CANCER INST, MA$249,647ZCA1
2024A multiplexed high-throughput platform to report pharmacologic alteration of cancer stem cell membrane potential and cell cycle state1R61CA278458-01A1 · under RFA-CA-23-002ROSTOMILY, ROBERT CST-PIERRE, FRANCOISMETHODIST HOSPITAL RESEARCH INSTITUTE, TX$240,484ZCA1
2024Multiplexed, Continuous Reporting of Gene Expression via CRISPR-mediated Transcriptional Activation1R61CA291201-01 · under RFA-CA-23-002ISHIZUKA, JEFFREY J.YALE UNIVERSITY, CT$234,919ZCA1
2024A Real-Time AI-Driven High-Throughput Proteomics Data Acquisition Method for Clinical Applications1R61CA287026-01 · under RFA-CA-23-002HAAS, WILHELMSEQUIST, LECIA V.MASSACHUSETTS GENERAL HOSPITAL, MA$234,218ZCA1
2024Proximity epigenomics for context-specific analysis of complex chromatin features1R61CA278503-01A1 · under RFA-CA-23-002OBERDOERFFER, PHILIPPJOHNS HOPKINS UNIVERSITY, MD$229,659ZCA1
2024Spatially resolved multi-omics sequencing of FFPE tissues at cellular level1R61CA287408-01A1 · under RFA-CA-23-002DENG, YANXIANGUNIVERSITY OF PENNSYLVANIA, PA$227,906ZCA1
2024Quantitative analysis and manipulation of chromosome dynamics in cancer organoids1R61CA278518-01A1 · under RFA-CA-23-002WITTMANN, TORSTENUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$226,505ZCA1
2024Development of A Directed Evolution Platform for RNA Methyltransferases.1R61CA291202-01 · under RFA-CA-23-002NIU, JIAZHOU, HUIQINGBOSTON COLLEGE, MA$217,388ZCA1
2024Tumor Metabolic Profiling by Multiplexed Single-Cell Lipid and mRNA Imaging1R61CA278450-01A1 · under RFA-CA-23-002HEILSHORN, SARAH CSTANFORD UNIVERSITY, CA$216,546ZCA1
2024Evolved Molecules that Destroy Cancer Relevant Proteins1R61CA291117-01 · under RFA-CA-23-002BIONDI, ELISAFOUNDATION FOR APPLIED MOLECULAR EVOLUTN, FL$215,564ZCA1
2024Profiling and perturbing the inheritance of drug-induced metabolic states in cancer with Inheritance-Seq1R61CA278536-01A1 · under RFA-CA-23-002BLAINEY, PAUL CLARKBROAD INSTITUTE, INC., MA$207,092ZCA1
2023Vesicle Epitope Transcript sequencing (VET-seq): Droplet-based Multiomic Profiling Platform for Single Vesicle Analysis1R61CA278559-01 · under RFA-CA-22-001LU, YUEUNIVERSITY OF UTAH, UT$243,486ZCA1
2023Development of methods for highly multiplexed quantification of cancer proteomes using large-scale nanobody libraries1R61CA281807-01 · under RFA-CA-22-001HACOHEN, NIRBROAD INSTITUTE, INC., MA$221,595ZCA1
2023High-throughput, purification-free, and ultrasensitive transmembrane nanosensor arrays for digital counting of microRNA biomarkers of intact exosomes1R61CA278558-01 · under RFA-CA-22-001HARIADI, RIZAL FAJARYAN, HAOARIZONA STATE UNIVERSITY-TEMPE CAMPUS, AZ$220,193ZCA1
2023Integrated Imaging Tools for Intercellular Chemokine Signalling1R61CA281657-01 · under RFA-CA-22-001LUKER, GARY DUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$218,790ZCA1
2023Program the Immune System against RAS-driven Cancer1R61CA278398-01 · under RFA-CA-22-001GAO, XIAOJING JWINSLOW, MONTE MEIERSTANFORD UNIVERSITY, CA$217,992ZCA1
2023Intersectional genetics-based biosensors for dormant cancer cells1R61CA278402-01 · under RFA-CA-22-001BRAVO-CORDERO, JOSE JAVIERICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY$217,772ZCA1
2023A Novel Assay to Individualize Resensitization of Iodine-Refractory Thyroid Cancer1R61CA278459-01 · under RFA-CA-22-001PRATX, GUILLEMSTANFORD UNIVERSITY, CA$216,862ZCA1
2023Microfluidic technology to isolate tumoricidal T-cells from peripheral blood1R61CA278531-01 · under RFA-CA-22-001SHIRURE, VENKTESHUNIVERSITY OF CALIFORNIA AT DAVIS, CA$216,584ZCA1
2023Triboelectric Ambient Mass Spectrometry Imaging of Renal Cell Carcinomas1R61CA281667-01 · under RFA-CA-22-001FERNANDEZ, FACUNDO MARTINGEORGIA INSTITUTE OF TECHNOLOGY, GA$215,136ZCA1
2023A novel multimodal ECM analysis platform for tumor characterization combining morphological and spectrochemical tissue imaging approaches.1R61CA281795-01 · under RFA-CA-22-001CAMPAGNOLA, PAUL JYESILKOY, FILIZUNIVERSITY OF WISCONSIN-MADISON, WI$208,402ZCA1
2023Single-Molecule High-Confidence Detection of miRNA Cancer Biomarkers1R61CA278445-01 · under RFA-CA-22-001DHAKAL, SOMAVIRGINIA COMMONWEALTH UNIVERSITY, VA$204,831ZCA1
2023A Generalizable Photo-Crosslinking Strategy to Identify Tyrosine Phosphatase Substrates1R61CA278452-01 · under RFA-CA-22-001SHAH, NEEL HCOLUMBIA UNIV NEW YORK MORNINGSIDE, NY$193,599ZCA1

Data: Grants.gov's daily extract and NIH's notice pages and award files, in ScienceGraph release conductgrants-2026-11-12-0.1.3. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.

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