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NIH funding notice RFA-DK-19-004

Silvio O. Conte Digestive Diseases Research Core Centers (P30 Clinical Trial Optional)

Closed on July 1, 2021.

Posted
March 13, 2019
Close date
July 1, 2021
Activity codes
P30
Institutes taking part
NIDDK

The notices it replaced

10 notices, oldest first, each with its awards since FY2014.

  1. Year not statedRFA-DK-06-017None since FY2014
  2. Year not statedRFA-DK-08-002None since FY2014
  3. Posted 2009RFA-DK-09-005None since FY2014
  4. Posted 2011RFA-DK-11-003None since FY2014
  5. Posted 2011RFA-DK-11-022None since FY2014
  6. Posted 2013RFA-DK-12-0237 awards
  7. Posted 2014RFA-DK-14-0125 awards
  8. Posted 2016RFA-DK-16-0194 awards
  9. Posted 2016RFA-DK-17-0012 awards
  10. Posted 2017RFA-DK-18-0017 awards
  11. Posted 2019RFA-DK-19-004This notice, closed · 8 awards

Replaced by RFA-DK-21-026.

Who won it before

Competing awards, new and renewals, since FY2014, under this notice and the notices it replaced.

Past awards
33
5 new, 28 renewals
Median first-year cost
$1,185,000
$39,126,400 in all
Institutions
22
25 contact PIs
Patents
90
from 16 funded projects

Awards by fiscal year

Fiscal years 2014 to 2026.

Most frequent institutions

  1. BOSTON CHILDREN'S HOSPITAL2
  2. CASE WESTERN RESERVE UNIVERSITY2
  3. CINCINNATI CHILDRENS HOSP MED CTR2
  4. MASSACHUSETTS GENERAL HOSPITAL2
  5. MAYO CLINIC ROCHESTER2

and 17 other institutions

Most frequent study sections

  1. Special Emphasis Panel (ZDK1 GRB-8 (M2))9
  2. Special Emphasis Panel (ZDK1 GRB-2 (O3))4
  3. Special Emphasis Panel (ZDK1 GRB-7 (J4))4
  4. Special Emphasis Panel (ZDK1 GRB-7 (M4))4
  5. Special Emphasis Panel (ZDK1 GRB-8 (J1))4

and 3 other study sections

33 awards under RFA-DK-19-004 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
FY2022Molecular and Cellular Basis for Digestive Diseases2P30DK058404-21Peek, Richard M.VANDERBILT UNIVERSITY MEDICAL CENTER, TNFirst-year cost $1,309,283Study section ZDK1
FY2022The Columbia University Digestive and Liver Disease Research Center1P30DK132710-01Schwabe, Robert F.COLUMBIA UNIVERSITY HEALTH SCIENCES, NYFirst-year cost $1,229,895Study section ZDK1
FY2022Center for Molecular Studies in Digestive and Liver Diseases2P30DK050306-26Wu, Gary D.UNIVERSITY OF PENNSYLVANIA, PAFirst-year cost $1,218,750Study section ZDK1
FY2022Digestive Health Center (DHC): Bench to Bedside Research in Pediatric Digestive Disease2P30DK078392-16Denson, Lee ArmisteadCINCINNATI CHILDRENS HOSP MED CTR, OHFirst-year cost $1,192,500Study section ZDK1
FY2021Integrated Epithelial and Muscosal Biology2P30DK034854-36Lencer, Wayne IBOSTON CHILDREN'S HOSPITAL, MAFirst-year cost $1,325,678Study section ZDK1
FY2021Center for the Study of Inflammatory Bowel Disease at Massachusetts General Hospital2P30DK043351-31Xavier, Ramnik JMASSACHUSETTS GENERAL HOSPITAL, MAFirst-year cost $1,270,598Study section ZDK1
FY2021Yale Liver Center2P30DK034989-36A1Nathanson, Michael HYALE UNIVERSITY, CTFirst-year cost $1,256,250Study section ZDK1
FY2021Center for Interdisciplinary Study of Inflammatory Intestinal DIsorders (C-IID)2P30DK042086-31Jabri, BanaUNIVERSITY OF CHICAGO, ILFirst-year cost $1,230,000Study section ZDK1
FY2020The Cleveland Digestive Diseases Research Core Center (DDRCC)2P30DK097948-06 · under RFA-DK-18-001Cominelli, FabioCASE WESTERN RESERVE UNIVERSITY, OHFirst-year cost $1,164,000Study section ZDK1
FY2020Center for Gastrointestinal Biology and Disease2P30DK034987-35 · under RFA-DK-18-001Sandler, Robert S.UNIV OF NORTH CAROLINA CHAPEL HILL, NCFirst-year cost $1,154,222Study section ZDK1
FY2020Host-environment interactions in the pathophysiology of digestive disease2P30DK052574-21 · under RFA-DK-18-001Davidson, Nicholas O.WASHINGTON UNIVERSITY, MOFirst-year cost $1,144,102Study section ZDK1
FY2020MUSC Digestive Disease Research Core Center1P30DK123704-01 · under RFA-DK-18-001Rockey, Don C.MEDICAL UNIVERSITY OF SOUTH CAROLINA, SCFirst-year cost $1,087,617Study section ZDK1
FY2019San Diego Digestive Diseases Research Center1P30DK120515-01 · under RFA-DK-18-001Eckmann, LarsSchnabl, Bernd G.UNIVERSITY OF CALIFORNIA, SAN DIEGO, CAFirst-year cost $1,181,250Study section ZDK1
FY2019Mayo Center for Cell Signaling in Gastroenterology2P30DK084567-11 · under RFA-DK-18-001Larusso, Nicholas F.MAYO CLINIC ROCHESTER, MNFirst-year cost $1,179,780Study section ZDK1
FY2019Pittsburgh Liver Research Center1P30DK120531-01 · under RFA-DK-18-001Monga, Satdarshan SinghUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PAFirst-year cost $1,170,620Study section ZDK1
FY2018UCSF Liver Center2P30DK026743-36 · under RFA-DK-17-001Maher, Jacquelyn J.UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CAFirst-year cost $1,175,692Study section ZDK1
FY2018Texas Medical Center Digestive Diseases Center2P30DK056338-16 · under RFA-DK-17-001Burrin, Douglas GEl-Serag, Hashem BBAYLOR COLLEGE OF MEDICINE, TXFirst-year cost $1,159,541Study section ZDK1
FY2017MOLECULAR AND CELLULAR BASIS FOR DIGESTIVE DISEASES2P30DK058404-16 · under RFA-DK-16-019Peek, Richard M.VANDERBILT UNIVERSITY MEDICAL CENTER, TNFirst-year cost $1,213,071Study section ZDK1
FY2017Center for Molecular Studies in Digestive and Liver Diseases2P30DK050306-21 · under RFA-DK-16-019Rustgi, Anil KUNIVERSITY OF PENNSYLVANIA, PAFirst-year cost $1,207,500Study section ZDK1
FY2017Digestive Health Center (DHC): Bench to Bedside Research in Pediatric Digestive Disease2P30DK078392-11 · under RFA-DK-16-019Bezerra, Jorge A.CINCINNATI CHILDRENS HOSP MED CTR, OHFirst-year cost $1,192,500Study section ZDK1
FY2017University of Michigan Center for Gastrointestinal Research2P30DK034933-31A1 · under RFA-DK-16-019Owyang, ChungUNIVERSITY OF MICHIGAN AT ANN ARBOR, MIFirst-year cost $972,429Study section ZDK1
FY2016Integrated Epithelial and Mucosal Biology2P30DK034854-31 · under RFA-DK-14-012Lencer, Wayne IBOSTON CHILDREN'S HOSPITAL, MAFirst-year cost $1,384,348Study section ZDK1
FY2016Center for the Study of Inflammatory Bowel Disease at Massachusetts General Hospital2P30DK043351-26 · under RFA-DK-14-012Xavier, Ramnik JMASSACHUSETTS GENERAL HOSPITAL, MAFirst-year cost $1,292,657Study section ZDK1
FY2016Hopkins Digestive Diseases Basic & Translational Research Core Center2P30DK089502-06 · under RFA-DK-14-012Donowitz, MarkJOHNS HOPKINS UNIVERSITY, MDFirst-year cost $1,189,912Study section ZDK1
FY2016IBD and Mucosal Inflammation, Immunology and Microbiology and the GI Tract2P30DK042086-26 · under RFA-DK-14-012Chang, Eugene BUNIVERSITY OF CHICAGO, ILFirst-year cost $1,185,000Study section ZDK1
FY2016USC Research Center for Liver Disease2P30DK048522-21A1 · under RFA-DK-14-012Kaplowitz, NeilUNIVERSITY OF SOUTHERN CALIFORNIA, CAFirst-year cost $1,161,965Study section ZDK1
FY2015Regulatory Factors in the GI Tract2P30DK052574-16 · under RFA-DK-12-023Davidson, Nicholas O.WASHINGTON UNIVERSITY, MOFirst-year cost $1,143,750Study section ZDK1
FY2015The Cleveland Digestive Diseases Research Core Center (DDRCC)1P30DK097948-01A1 · under RFA-DK-12-023Cominelli, FabioCASE WESTERN RESERVE UNIVERSITY, OHFirst-year cost $1,110,993Study section ZDK1
FY2015Center for Gastrointestinal Biology and Disease2P30DK034987-30 · under RFA-DK-12-023Sandler, Robert S.UNIV OF NORTH CAROLINA CHAPEL HILL, NCFirst-year cost $1,102,766Study section ZDK1
FY2015CURE: Digestive Diseases Research Center2P30DK041301-26 · under RFA-DK-12-023Rozengurt, Juan EnriqueUNIVERSITY OF CALIFORNIA LOS ANGELES, CAFirst-year cost $936,455Study section ZDK1
FY2014Liver Pathobiology and Gene Therapy Research Core Center2P30DK041296-26 · under RFA-DK-12-023Wolkoff, Allan WALBERT EINSTEIN COLLEGE OF MEDICINE, NYFirst-year cost $1,252,500Study section ZDK1
FY2014Mayo Center for Cell Signaling in Gastroenterology2P30DK084567-06 · under RFA-DK-12-023Larusso, Nicholas F.MAYO CLINIC ROCHESTER, MNFirst-year cost $1,192,500Study section ZDK1
FY2014Silvio O. Conte Digestive Diseases Research Core Centers2P30DK034989-31 · under RFA-DK-12-023Nathanson, Michael HYALE UNIVERSITY, CTFirst-year cost $1,138,276Study section ZDK1
Newest fiscal year first, then first-year cost.

Patents from its funded projects

90 patents name 16 of the 22 funded projects. The newest 5, by patent number.

  1. US 12,617,755 (opens the patent at USPTO, a PDF, in a new tab)COMPOSITIONS AND METHODS FOR TREATING METABOLIC DISEASEGranted May 5, 2026 to The Regents of the University of CaliforniaP30DK041301 · UNIVERSITY OF CALIFORNIA LOS ANGELES, CA
  2. US 12,612,617 (opens the patent at USPTO, a PDF, in a new tab)MITOCHONDRIAL GENOME EDITING METHODSGranted April 28, 2026 to Mayo Foundation for Medical Education and ResearchP30DK084567 · MAYO CLINIC ROCHESTER, MN
  3. US 12,590,288 (opens the patent at USPTO, a PDF, in a new tab)METHOD OF TREATING AN INFLAMMATORY DISEASE BY ADMINISTERING AN AGENT WHICH BINDS A SURFACE RECEPTOR ON A TUFT CELL THAT INDUCES AN ILC CLASS 2 INFLAMMATORY RESPONSEGranted March 31, 2026 to The Broad Institute, Inc., Massachusetts Institute of Technology and The General Hospital CorporationP30DK043351 · MASSACHUSETTS GENERAL HOSPITAL, MA
  4. US 12,577,273 (opens the patent at USPTO, a PDF, in a new tab)SMALL MOLECULE MODULATORS OF GUT BACTERIAL BILE ACID METABOLISMGranted March 17, 2026 to President and Fellows of Harvard CollegeP30DK034854 · BOSTON CHILDREN'S HOSPITAL, MA
  5. US 12,474,353 (opens the patent at USPTO, a PDF, in a new tab)METHODS AND MATERIALS FOR ASSESSING AND TREATING OBESITYGranted November 18, 2025 to Mayo Foundation for Medical Education and ResearchP30DK084567 · MAYO CLINIC ROCHESTER, MN

Each number opens the patent at USPTO, beside the project NIH ties it to and that project's institution. NIH ties a patent to a project, not to a year of its funding, and says its list is incomplete. The grant date and the owners are USPTO's: the organizations the patent names as assignees on the day it was granted. Source: United States Patent and Trademark Office, www.uspto.gov, which does not endorse ScienceDex.

Data: Grants.gov's daily extract and NIH's notice pages, award files and patents file, in ScienceGraph release conductgrants-2026-11-12-0.3.1. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.

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