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NIH funding notice RFA-ES-21-006

CCRP Initiative: Chemical Threat Agent-induced Pulmonary and Ocular Pathophysiological Mechanisms (R01 Clinical Trial Not Allowed)

Closed on September 20, 2023.

Posted
June 25, 2021
Close date
September 20, 2023
Activity codes
Not stated on the notice page
Institutes taking part
Not stated on the notice page

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

Its page was not saved, so the notices it replaced are not known.

Who won it before

24 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $11,251,104 in first-year total cost, median $467,882.

Most frequent study sections

  1. Special Emphasis Panel[ZES1 LWJ-D (CA)]11
  2. ZES1-LWJ-D(CA)7
  3. Special Emphasis Panel[ZES1 LWJ-D (R1)]6

Most frequent institutions

  1. UNIVERSITY OF ALABAMA AT BIRMINGHAM3
  2. SAINT LOUIS UNIVERSITY2
  3. SCHEPENS EYE RESEARCH INSTITUTE2
  4. UNIVERSITY OF COLORADO DENVER2
  5. WAKE FOREST UNIVERSITY HEALTH SCIENCES2
Competing awards under RFA-ES-21-006 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2024Immune Mechanisms of Chronic Ocular Damage after Acute Exposure to Nitrogen Mustard1R01EY035215-01A1CHEN, YIHESCHEPENS EYE RESEARCH INSTITUTE, MA$589,071ZES1
2024Pathophysiology of Chronic and Delayed Mustard Gas Keratopathy1R01EY035221-01A1DJALILIAN, ALI RUNIVERSITY OF ILLINOIS AT CHICAGO, IL$480,990ZES1
2024Ocular mustard keratopathy elicits induced autophagy, which is detrimental to the cornea1R56EY036320-01PENG, HANNORTHWESTERN UNIVERSITY AT CHICAGO, IL$468,734ZES1
2024Role of proteolytic extracellular vesicles in halogen gas dependent chronic lung injury1R01ES036518-01GENSCHMER, KRISTOPHER R.PATEL, RAKESH P.UNIVERSITY OF ALABAMA AT BIRMINGHAM, AL$445,500ZES1
2023Mechanisms underlying mustard gas-induced conjunctival injury and use of lipid mediators as medical countermeasures1R56EY035213-01DARTT, DARLENE AMASLI, SHARMILASCHEPENS EYE RESEARCH INSTITUTE, MA$583,250ZES1
2023Mitochondria and Mustard Damage at the Ocular Surface1R01EY035220-01FINI, M ELIZABETHTUFTS MEDICAL CENTER, MA$537,448ZES1
2023Pathophysiological Mechanisms of Chemical-Induced Acute Lung Injury1R01ES034490-01A1LEIKAUF, GEORGE DOUGLASUNIVERSITY OF CINCINNATI, OH$499,348ZES1
2023Unraveling the corneal and retinal mechanisms of chemical injury1R56EY035219-01MOHAN, ROYCEUNIVERSITY OF CONNECTICUT SCH OF MED/DNT, CT$498,248ZES1
2023Discovery of phosgene and chlorine gas modes of action and therapeutic targets using chemoproteomic profiling strategies1R56ES035364-01ACHANTA, SATYANARAYANALIN, VIVIAN SBATTELLE PACIFIC NORTHWEST LABORATORIES, WA$494,162ZES1
2023Soluble epoxide hydrolase and epoxide fatty acid involvement in corneal injury after ammonia exposure: Mechanisms of injury and potential therapeutics using sEH inhibitors and biostable EpFA mimics.1R01EY035222-01HAMMOCK, BRUCE DWATSKY, MITCHELL AAUGUSTA UNIVERSITY, GA$484,200ZES1
2023Mechanistic Understanding of Mustard Gas Toxicity in the Retina using a Minipig Model1R56EY035223-01CHAURASIA, SHYAM SUNDERMOHAN, RAJIV RAVINDRAMEDICAL COLLEGE OF WISCONSIN, WI$482,242ZES1
2023Understanding Mustard Vesicants Distribution and Toxicity in the Eye Using In Vivo and In Silico Models1R01EY034140-01A1GERMAN, CARRIETEWARI-SINGH, NEERAMICHIGAN STATE UNIVERSITY, MI$467,030ZES1
2023Vascular injury and repair predict divergent late onset cardiovascular morbidities after chlorine and sulfur mustard exposure1R01ES035431-01VERESS, LIVIA AGNESUNIVERSITY OF COLORADO DENVER, CO$462,958ZES1
2023Mast Cell Activation as a Common Mechanism of Pulmonary Toxicity by Chemical Threat Agents1R56ES034386-01A1BAUER, ALISON KBROWN, JARED MICHAELUNIVERSITY OF COLORADO DENVER, CO$462,501ZES1
2023Pulmonary Pathophysiologic Mechanisms of Chloropicrin and Phosgene1R01ES034419-01A1VAN WINKLE, LAURA SUNIVERSITY OF CALIFORNIA AT DAVIS, CA$453,213ZES1
2023Extracellular vesicles as mediators of injury in inhaled exposures to toxic chemicals.1R56ES034423-01A1AHMAD, AFTABAHMAD, SHAMAUNIVERSITY OF ALABAMA AT BIRMINGHAM, AL$445,500ZES1
2023Characterizing chemical threat agent exposures using a lung-on-a-chip platform and multi-omic analysis of common pathophysiological mechanisms1R01ES034416-01A1MURPHY, SEAN VINCENTWAKE FOREST UNIVERSITY HEALTH SCIENCES, NC$310,000ZES1
2023Lipid and metabolic mechanisms responsible for phosgene and phosphorus trichloride exposure toxicity1R01ES035365-01EDWARDS, JAMES LFORD, DAVID A.SAINT LOUIS UNIVERSITY, MO$303,000ZES1
2022Pulmonary cell fate and lung repair in rodent and porcine models of chlorine and phosgene inhalation injuries1R01ES034387-01ACHANTA, SATYANARAYANAJORDT, SVEN-ERICDUKE UNIVERSITY, NC$482,024ZES1
2022The Role of Master Epigenetic Regulators in Ocular Chemical Injury1R01EY034266-01MOTAMEDI, MASSOUDZHANG, WENBOUNIVERSITY OF TEXAS MED BR GALVESTON, TX$480,000ZES1
2022Late/chronic corneal injury following threat chemical exposure1R01EY034319-01GUPTA, SUNEELMOHAN, RAJIV RAVINDRATRIPATHI, RATNAKARUNIVERSITY OF MISSOURI-COLUMBIA, MO$465,287ZES1
2022Halolipid-Neutrophil Extracellular Trap Axis in Halogen Lung Injury1R01ES034383-01FORD, DAVID A.PATEL, RAKESH P.SAINT LOUIS UNIVERSITY, MO$462,883ZES1
2022Toxic Mechanisms of Vesicating Chemicals in the Eye1R01EY034139-01MCNUTT, PATRICK MICHAELWAKE FOREST UNIVERSITY HEALTH SCIENCES, NC$448,015ZES1
2022The mechanism of vesicant-induced ocular injury1R01EY034110-01GORBATYUK, MARINAUNIVERSITY OF ALABAMA AT BIRMINGHAM, AL$445,500ZES1

Data: Grants.gov's daily extract and NIH's notice pages and award files, in ScienceGraph release conductgrants-2026-11-10-0.1.1. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.

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RFA-ES-21-006: CCRP Initiative: Chemical Threat Agent-induced Pulmonary and Ocular Pathophysiological Mechanisms (R01 Clinical Trial Not Allowed) | ScienceDex | ConductScience