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NIH funding notice RFA-HL-16-024

NHLBI Outstanding Investigator Award (OIA) (R35)

Closed on April 15, 2018.

Posted
December 10, 2015
Close date
April 15, 2018
Activity codes
R35
Institutes taking part
NHLBI

Read the notice on Grants.gov ยท NIH Guide page

The notices it replaced

Its page names no earlier notice: it is new, or it does not say.

Replaced by RFA-HL-20-011.

Who won it before

69 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $57,673,073 in first-year total cost, median $910,734.

Most frequent study sections

  1. Special Emphasis Panel[ZHL1 CSR-R (O3)]37
  2. Special Emphasis Panel[ZHL1 CSR-I (O1)]32

Most frequent institutions

  1. COLUMBIA UNIVERSITY HEALTH SCIENCES5
  2. UNIVERSITY OF CALIFORNIA LOS ANGELES4
  3. YALE UNIVERSITY4
  4. UNIVERSITY OF CALIFORNIA, SAN DIEGO3
  5. UNIVERSITY OF MICHIGAN AT ANN ARBOR3
Competing awards under RFA-HL-16-024 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2019Molecular and Translational Studies in Hematologic Disorders1R35HL145262-01LOPEZ, JOSE ARONBLOODWORKS, WA$1,105,665ZHL1
2019Toward a Mechanism-Based Approach to Treating Cardiac Arrhythmia1R35HL144980-01KNOLLMANN, BJORN CVANDERBILT UNIVERSITY MEDICAL CENTER, TN$1,020,000ZHL1
2019Airway epithelial cell gene regulation: new mechanisms and therapeutic strategies1R35HL145235-01ERLE, DAVID JUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$961,617ZHL1
2019A Mechanistic and Translational Research Program Linking Impaired Resolution, Defective Efferocytosis, and Clonal Hematopoiesis to the Formation of Clinically Dangerous Atherosclerotic Plaques1R35HL145228-01TABAS, IRA ACOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$955,996ZHL1
2019Defining and Controlling Airway Disease1R35HL145242-01HOLTZMAN, MICHAEL JWASHINGTON UNIVERSITY, MO$939,000ZHL1
2019Novel Functions of Lung Macrophages and Fibroblasts in Pulmonary Inflammation and Fibrosis1R35HL144979-01PETERS-GOLDEN, MARC LUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$928,378ZHL1
2019Vascular macrophages and T cells in atherosclerosis1R35HL145241-01LEY, KLAUS F.LA JOLLA INSTITUTE FOR IMMUNOLOGY, CA$927,585ZHL1
2019PPARG-dependent Mechanisms Control Endothelial-Smooth Muscle Coordination, Arterial Pressure, Vasomotor Function and Arterial Stiffness1R35HL144807-01SIGMUND, CURT DANIELMEDICAL COLLEGE OF WISCONSIN, WI$924,000ZHL1
2019Organizational strategies for improving evidence-uptake in intensive care1R35HL144804-01KAHN, JEREMY MUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$922,387ZHL1
2019Capillaries as a Sensory Web that Controls Cerebral Blood Flow in Health and Disease1R35HL140027-01NELSON, MARK TUNIVERSITY OF VERMONT & ST AGRIC COLLEGE, VT$919,963ZHL1
2019Role of the giant protein titin in cardiac health and disease1R35HL144998-01GRANZIER, HENK L.UNIVERSITY OF ARIZONA, AZ$884,369ZHL1
2019Renewing the heart: cardiomyocyte cell cycle regulation1R35HL144984-01EVANS, SYLVIA MUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$865,334ZHL1
2019Immunobiology of Lung Injury and Fibrosis1R35HL144481-01MOORE, BETHANY B.UNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$847,613ZHL1
2019Cilia in Heart Development and Disease1R35HL145249-01BRUECKNER, MARTINAYALE UNIVERSITY, CT$726,127ZHL1
2019Small GTPases in the biology of platelets and megakaryocytes1R35HL144976-01BERGMEIER, WOLFGANGUNIV OF NORTH CAROLINA CHAPEL HILL, NC$561,180ZHL1
2019Translational Control of Megakaryocyte and Platelet Gene Expression in Disease1R35HL145237-01WEYRICH, ANDREW SUNIVERSITY OF UTAH, UT$253,797ZHL1
2018Insights into the Molecular and Cellular Mechanisms governing Endothelial Function1R35HL139945-01SESSA, WILLIAM CYALE UNIVERSITY, CT$1,005,000ZHL1
2018Embryonic origins of endothelial heterogeneity1R35HL140017-01LAWSON, NATHAN DUNIV OF MASSACHUSETTS MED SCH WORCESTER, MA$1,005,000ZHL1
2018Imaging organ system interfaces in ischemic heart disease1R35HL139598-01NAHRENDORF, MATTHIASMASSACHUSETTS GENERAL HOSPITAL, MA$987,881ZHL1
2018Basic Investigation and Translational Applications Concerning the Cell and Molecular Biology of Blood and Vascular Cells1R35HL139937-01NEWMAN, PETER JVERSITI WISCONSIN, INC., WI$986,967ZHL1
2018Cardiac lineage determination and nuclear architecture1R35HL140018-01EPSTEIN, JONATHAN A.UNIVERSITY OF PENNSYLVANIA, PA$957,952ZHL1
2018CaMKII signaling in physiology, heart failure and arrhythmias1R35HL140034-01ANDERSON, MARK EJOHNS HOPKINS UNIVERSITY, MD$950,658ZHL1
2018Tie2-driven vascular control in critical illness1R35HL139424-01PARIKH, SAMIR MBETH ISRAEL DEACONESS MEDICAL CENTER, MA$939,488ZHL1
2018Mechanisms of vascular and valvular calcification1R35HL139602-01GIACHELLI, CECILIA MUNIVERSITY OF WASHINGTON, WA$931,250ZHL1
2018Eating, Activity, and Weight-Related Problems Across the Life Course in Diverse Populations1R35HL139853-01NEUMARK-SZTAINER, DIANNE RUNIVERSITY OF MINNESOTA, MN$927,214ZHL1
2018Vascular Growth and Regeneration1R35HL140014-01IRUELA-ARISPE, M. LUISAUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$924,642ZHL1
2018MOLECULAR AND CELLULAR CONTROL OF ANGIOGENESIS1R35HL139950-01BAUTCH, VICTORIA LUNIV OF NORTH CAROLINA CHAPEL HILL, NC$922,296ZHL1
2018Potassium Channels and Control of Cardiovascular Function1R35HL140024-01NICHOLS, COLIN GWASHINGTON UNIVERSITY, MO$915,000ZHL1
2018CD4_T-cell_Immunity_in_the_Lung1R35HL139930-01KOLLS, JAY KTULANE UNIVERSITY OF LOUISIANA, LA$860,539ZHL1
2018Variant Hemoglobin and Cardiorespiratory Regulation in Humans1R35HL139854-01JOYNER, MICHAEL JMAYO CLINIC ROCHESTER, MN$806,184ZHL1
2018Biochemistry and Pathophysiology of Factor XI and Contact Activation1R35HL140025-01GAILANI, DAVIDVANDERBILT UNIVERSITY MEDICAL CENTER, TN$790,000ZHL1
2018Genomics of Pulmonary Vascular Disease1R35HL140019-01ALDRED, MICHEALA AINDIANA UNIVERSITY INDIANAPOLIS, IN$777,434ZHL1
2018Investigating Mechanisms for Lipid Transport in Health and Disease1R35HL139725-01YOUNG, STEPHEN G.UNIVERSITY OF CALIFORNIA LOS ANGELES, CA$775,320ZHL1
2018Deconvoluting the Vascular Adhesome1R35HL139947-01GINSBERG, MARK HOWARDUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$774,183ZHL1
2018Controlling Influences of Oxygen Tension and CD26/DPP4 Enzymatic Activity on Regulation of Hematopoietic Stem/Progenitor Cells and Hematopoiesis During Health, Ageing, and Disease1R35HL139599-01BROXMEYER, HAL E.INDIANA UNIVERSITY INDIANAPOLIS, IN$768,104ZHL1
2018Mechanisms of Immune Activation in Hypertension1R35HL140016-01HARRISON, DAVID GVANDERBILT UNIVERSITY MEDICAL CENTER, TN$767,077ZHL1
2018Molecular mechanism and targeting of chronic pain in sickle cell disease1R35HL140031-01WANG, ZAIJIE JIMUNIVERSITY OF ILLINOIS AT CHICAGO, IL$661,398ZHL1
2018SOD3 regulation of redox sensitive signaling in pulmonary vascular diseases1R35HL139726-01NOZIK, EVA S.UNIVERSITY OF COLORADO DENVER, CO$571,435ZHL1
2017Phenotypic and Molecular Signatures for Sleep Apnea and Related Morbidities1R35HL135818-01REDLINE, SUSAN S.BRIGHAM AND WOMEN'S HOSPITAL, MA$1,057,510ZHL1
2017The Identification and characterization of genetic variants underlying cardiovascular diseases1R35HL135767-01MANI, ARYAYALE UNIVERSITY, CT$1,005,000ZHL1
2017Leveraging Protein Kinase G-1 Nanodomain Control and Molecular Targeting to Enhance its Therapeutic Use Against Myocardial Disease1R35HL135827-01KASS, DAVID ALANJOHNS HOPKINS UNIVERSITY, MD$994,861ZHL1
2017Beyond the barrier: alveolar epithelial cell biology in health and disease1R35HL135747-01BOROK, ZEAUNIVERSITY OF SOUTHERN CALIFORNIA, CA$990,000ZHL1
2017Phenotyping Genetic Disorders of Hepatic Lipid and Lipoprotein Metabolism in Cells, Mice, and Men1R35HL135833-01GINSBERG, HENRY NCOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$953,882ZHL1
2017KLF control of aging and age-associated cardiovascular disease1R35HL135789-01JAIN, MUKESH KUMARCASE WESTERN RESERVE UNIVERSITY, OH$951,000ZHL1
2017Mechanisms Controlling Expansion and Lineage Specification of Airway Progenitors in Development and Disease1R35HL135834-01CARDOSO, WELLINGTON V.COLUMBIA UNIVERSITY HEALTH SCIENCES, NY$948,730ZHL1
2017AIBP therapy1R35HL135737-01MILLER, YURYUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$930,000ZHL1
2017Mechanisms of sphingolipid signaling in vascular health and disease1R35HL135821-01HLA, TIMOTHY TUNBOSTON CHILDREN'S HOSPITAL, MA$926,656ZHL1
2017S-glutathionylation chemistry in fibrotic lung remodeling1R35HL135828-01JANSSEN-HEININGER, YVONNE M. W.UNIVERSITY OF VERMONT & ST AGRIC COLLEGE, VT$923,815ZHL1
2017THE MITOCHONDRIAL DYNAMISM/FITNESS/BIOGENESIS INTERACTOME IN CARDIAC DISEASE1R35HL135736-01DORN, GERALD W.WASHINGTON UNIVERSITY, MO$915,000ZHL1
2017Signaling mechanisms and functions related to patho-physiology of vascular, lung and blood systems1R35HL135805-01WU, DIANQINGYALE UNIVERSITY, CT$912,314ZHL1
2017Omics Phenotyping for Identifying Molecular Signatures of the Healthy and Failing Heart: An Integrated Data Science Platform1R35HL135772-01PING, PEIPEIUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$910,734ZHL1
2017Defining novel mechanisms for human arrhythmia1R35HL135754-01MOHLER, PETER J.OHIO STATE UNIVERSITY, OH$908,050ZHL1
2017How inflammation and thrombosis fuel disease and aging: Focus on NETs1R35HL135765-01WAGNER, DENISA DBOSTON CHILDREN'S HOSPITAL, MA$885,000ZHL1
2017A Novel Exosomal Inflammatory Pathway1R35HL135710-01BLALOCK, J EDWINUNIVERSITY OF ALABAMA AT BIRMINGHAM, AL$877,566ZHL1
2017Pneumonia Biology1R35HL135756-01MIZGERD, JOSEPH PBOSTON UNIVERSITY MEDICAL CAMPUS, MA$868,938ZHL1
2017Pediatric Heart Disease: Getting from Mutations to Therapeutics1R35HL135742-01GELB, BRUCE DICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY$856,106ZHL1
2017Non-coding RNA regulation of cholesterol homeostasis and atherosclerosis1R35HL135799-01MOORE, KATHRYN JNEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY$823,175ZHL1
2017Emergency Myelopoiesis Pathways in the Control of Blood Production1R35HL135763-01PASSEGUE, EMMANUELLECOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$816,806ZHL1
2017A Gata456 Pipeline of Discovery1R35HL135778-01EVANS, TODD RWEILL MEDICAL COLL OF CORNELL UNIV, NY$810,723ZHL1
2017Innate Immune Clearance of Host-Adapted Pulmonary Pathogens1R35HL135800-01PRINCE, ALICE SCOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$796,640ZHL1
2017Neural control of breathing1R35HL135779-01FELDMAN, JACK LUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$781,655ZHL1
2017Role of LDL receptor family members in protecting the vasculature1R35HL135743-01STRICKLAND, DUDLEY K.UNIVERSITY OF MARYLAND BALTIMORE, MD$770,872ZHL1
2017Ion Channels and Membrane Receptors in Pulmonary Arterial Hypertension1R35HL135807-01YUAN, JASON X JUNIVERSITY OF ARIZONA, AZ$767,500ZHL1
2017The Molecular Genetics of Hemostasis1R35HL135793-01GINSBURG, DAVIDUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$578,742ZHL1
2017Thiol Isomerases in Hemostasis and Thrombosis1R35HL135775-01FLAUMENHAFT, ROBERT CBETH ISRAEL DEACONESS MEDICAL CENTER, MA$432,500ZHL1
2017Macrophages in homeostasis and cardiovascular disease1R35HL135752-01SWIRSKI, FILIP KMASSACHUSETTS GENERAL HOSPITAL, MA$427,500ZHL1
2017Structure-Function and Roles of Protease-Activated Receptors1R35HL135755-01COUGHLIN, SHAUN R.UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$396,250ZHL1
2017Therapeutic Implications of Molecular Defects in Bone Marrow Failure1R35HL135795-01MACIEJEWSKI, JAROSLAW P.CLEVELAND CLINIC LERNER COM-CWRU, OH$396,250ZHL1
2017Mechanisms in Blood Clotting1R35HL135823-01MORRISSEY, JAMES H.UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN, IL$311,265ZHL1

Data: Grants.gov's daily extract and NIH's notice pages and award files, in ScienceGraph release conductgrants-2026-11-10-0.1.1. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.

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